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Reproductive Technology
Reproductive technology encompasses all current and anticipated uses of technology in human and animal reproduction, including assisted reproductive technology (ART), contraception and others. It is also termed Assisted Reproductive Technology, where it entails an array of appliances and procedures that enable the realization of safe, improved and healthier reproduction. While this is not true of all people, for an array of married couples, the ability to have children is vital. But through the technology, infertile couples have been provided with options that would allow them to conceive children. Overview Assisted reproductive technology Assisted reproductive technology (ART) is the use of reproductive technology to treat low fertility or infertility. Modern technology can provide infertile couples with assisted reproductive technologies. The natural method of reproduction has become only one of many new techniques used today. There are millions of couples that do not have the ab ...
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Contraception
Birth control, also known as contraception, anticonception, and fertility control, is the use of methods or devices to prevent pregnancy. Birth control has been used since ancient times, but effective and safe methods of birth control only became available in the 20th century. Planning, making available, and using human birth control is called family planning. Some cultures limit or discourage access to birth control because they consider it to be morally, religiously, or politically undesirable. The World Health Organization and United States Centers for Disease Control and Prevention provide guidance on the safety of birth control methods among women with specific medical conditions. The most effective methods of birth control are sterilization by means of vasectomy in males and tubal ligation in females, intrauterine devices (IUDs), and contraceptive implant, implantable birth control. This is followed by a number of hormonal contraceptive, hormone-based methods includin ...
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Embryo Transfer
Embryo transfer refers to a step in the process of assisted reproduction in which embryos are placed into the uterus of a female with the intent to establish a pregnancy. This technique - which is often used in connection with in vitro fertilization (IVF) - may be used in humans or in other animals, in which situations and goals may vary. Embryo transfer can be done at day two or day three, or later in the blastocyst stage, which was first performed in 1984. Factors that can affect the success of embryo transfer include the endometrial receptivity, embryo quality, and embryo transfer technique. Fresh versus frozen Embryos can be either "fresh" from fertilized egg cells of the same menstrual cycle, or "frozen", that is they have been generated in a preceding cycle and undergone embryo cryopreservation, and are thawed just prior to the transfer, which is then termed "frozen embryo transfer" (FET). The outcome from using cryopreserved embryos has uniformly been positive wit ...
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Ovarian Reserve
Ovarian reserve is a term that is used to determine the capacity of the ovary to provide egg cells that are capable of fertilization resulting in a healthy and successful pregnancy. With advanced maternal age, the number of egg cell that can be successfully recruited for a possible pregnancy declines, constituting a major factor in the inverse correlation between age and female fertility. While there is no known method for assessing the ovarian reserve of individual women, indirect determination of ovarian reserve is important in the treatment of infertility. Establishment The ovary is generally thought of as an egg bank from which the woman draws during her reproductive life. The human ovary contains a population of primordial follicles. At 18–22 weeks post-conception, the female ovary contains its peak number of follicles (about 300,000 in the average case, but individual peak populations range from 35,000 to 2.5 million). The size of the initial ovarian reserve is strongly i ...
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Family Planning
Family planning is the consideration of the number of children a person wishes to have, including the choice to have no children, and the age at which they wish to have them. Things that may play a role on family planning decisions include marital situation, career or work considerations, or financial situations. If sexually active, family planning may involve the use of Birth control, contraception (birth control) and other techniques to control the timing of Human reproduction, reproduction. Other aspects of family planning aside from contraception include sex education, prevention and management of sexually transmitted infections, pre-conception counseling and pregnancy#Management, management, and infertility management.World Health Organization. (n.d.)Sexual and Reproductive Health. Retrieved on 30 October 2019. Family planning, as defined by the United Nations and the World Health Organization, encompasses services leading up to conception. Abortion is another form of family ...
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Yale University
Yale University is a Private university, private Ivy League research university in New Haven, Connecticut, United States. Founded in 1701, Yale is the List of Colonial Colleges, third-oldest institution of higher education in the United States, and one of the nine colonial colleges chartered before the American Revolution. Yale was established as the Collegiate School in 1701 by Congregationalism in the United States, Congregationalist clergy of the Connecticut Colony. Originally restricted to instructing ministers in theology and sacred languages, the school's curriculum expanded, incorporating humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first Doctor of Philosophy, PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew rapidly after 1890 due to the expansion of the physical campus and its scientif ...
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University Of Southern California
The University of Southern California (USC, SC, or Southern Cal) is a Private university, private research university in Los Angeles, California, United States. Founded in 1880 by Robert M. Widney, it is the oldest private research university in California, and has an enrollment of more than 49,000 students. The university is composed of one Liberal arts education, liberal arts school, the University of Southern California academics, Dornsife College of Letters, Arts and Sciences, and 22 Undergraduate education, undergraduate, Graduate school, graduate, and professional schools, enrolling roughly 21,000 undergraduate and 28,500 Postgraduate education, post-graduate students from all fifty U.S. states and more than 115 countries. It is a member of the Association of American Universities, which it joined in 1969. USC sponsors a variety of intercollegiate sports and competes in the National Collegiate Athletic Association (NCAA) and the Big Ten Conference. Members of USC's sports ...
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University Of Texas Health Science Center At Houston
The University of Texas Health Science Center at Houston (UTHealth Houston) is a public academic health science center in Houston, Texas, United States. It was created in 1972 by The University of Texas System Board of Regents. It is located in the Texas Medical Center, the largest medical center in the world. It is composed of six schools: McGovern Medical School, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, UTHealth School of Dentistry, Cizik School of Nursing, UTHealth School of Biomedical Informatics and UTHealth School of Public Health. About Established in 1972 by The University of Texas System Board of Regents, The University of Texas Health Science Center at Houston (UTHealth) is Houston's Health University and Texas' resource for health care education, innovation, scientific discovery, and excellence in patient care. The most comprehensive academic health center in The UT System and the U.S. Gulf Coast regi ...
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Vanderbilt University
Vanderbilt University (informally Vandy or VU) is a private university, private research university in Nashville, Tennessee, United States. Founded in 1873, it was named in honor of shipping and railroad magnate Cornelius Vanderbilt, who provided the school its initial $1 million endowment in the hopes that his gift and the greater work of the university would help to heal the sectional wounds inflicted by the American Civil War. Vanderbilt is a founding member of the Southeastern Conference and has been the conference's only private school since 1966. The university comprises ten schools and enrolls nearly 13,800 students from the US and 70 foreign countries. Vanderbilt is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Several research centers and institutes are affiliated with the university, including the Robert Penn Warren, Robert Penn Warren Center for the Humanities, the Freedom Foru ...
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Norfolk
Norfolk ( ) is a Ceremonial counties of England, ceremonial county in England, located in East Anglia and officially part of the East of England region. It borders Lincolnshire and The Wash to the north-west, the North Sea to the north and east, Cambridgeshire to the west, and Suffolk to the south. The largest settlement is the city of Norwich. The county has an area of and a population of 859,400. It is largely rural with few large towns: after Norwich (147,895), the largest settlements are King's Lynn (42,800) in the north-west, Great Yarmouth (38,693) in the east, and Thetford (24,340) in the south. For local government purposes Norfolk is a non-metropolitan county with seven districts. The centre of Norfolk is gently undulating lowland. To the east are the Broads, a network of rivers and lakes which extend into Suffolk and which are protected by the Broads Authority, which give them a similar status to a National parks of England and Wales, national park. To the west the ...
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Preimplantation Genetic Diagnosis
Preimplantation genetic diagnosis (PGD or PIGD) is the genetic profiling of embryos prior to implantation (as a form of embryo profiling), and sometimes even of oocytes prior to fertilization. PGD is considered in a similar fashion to prenatal diagnosis. When used to screen for a specific genetic disease, its main advantage is that it avoids selective abortion, as the method makes it highly likely that the baby will be free of the disease under consideration. PGD thus is an adjunct to assisted reproductive technology, and requires in vitro fertilization (IVF) to obtain oocytes or embryos for evaluation. Embryos are generally obtained through blastomere or blastocyst biopsy. The latter technique has proved to be less deleterious for the embryo, therefore it is advisable to perform the biopsy around day 5 or 6 of development. The world's first PGD was performed by Handyside, Kontogianni and Winston at the Hammersmith Hospital in London. "Female embryos were selectively transfer ...
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In Vitro Generated Gametes
A gamete ( ) is a haploid cell that fuses with another haploid cell during fertilization in organisms that reproduce sexually. Gametes are an organism's reproductive cells, also referred to as sex cells. The name gamete was introduced by the German cytologist Eduard Strasburger in 1878. Gametes of both mating individuals can be the same size and shape, a condition known as isogamy. By contrast, in the majority of species, the gametes are of different sizes, a condition known as anisogamy or heterogamy that applies to humans and other mammals. The human ovum has approximately 100,000 times the volume of a single human sperm cell. The type of gamete an organism produces determines its sex and sets the basis for the sexual roles and sexual selection. In humans and other species that produce two morphologically distinct types of gametes, and in which each individual produces only one type, a female is any individual that produces the larger type of gamete called an ovum, and ...
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Intracytoplasmic Sperm Injection
Intracytoplasmic sperm injection (ICSI ) is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus. With this method, the acrosome reaction is skipped. There are several differences between classic IVF and ICSI. However, the steps to be followed before and after insemination are the same. In terms of insemination, ICSI needs only one sperm cell per oocyte, while IVF needs 50,000–100,000. This is because the acrosome reaction has to take place and thousands of sperm cells have to be involved in IVF. Once fertilized, the egg is transformed into a pre-embryo and it has to be transferred to the uterus to continue its development. The first human pregnancy generated by ICSI was carried out in 1991 by Gianpiero Palermo and his team. Round spermatid injection (ROSI) Round spermatid injecti ...
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