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Rauvolfia
''Rauvolfia'' (sometimes spelled ''Rauwolfia'') is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae. The genus is named to honor Leonhard Rauwolf. The genus can mainly be found in Tropics, tropical regions of Africa, Asia, Latin America, and various oceanic islands. Spelling The International Code of Nomenclature for algae, fungi, and plants stipulates that the genus name was established by Carl Linnaeus in his 1753 book ''Species Plantarum'', which cites his earlier description which states in Botanical Latin#Alphabet, Botanical Latin that the name is dedicated "to Leonhard Rauwolf": "''Leon. Rauvolfio''". Although some subsequent authors hypercorrection, hypercorrected the Classical Latin letter "v" to a modern "w", this is not accepted by the code of nomenclature. Chemical constituents ''Rauvolfia serpentina'', commonly known as Indian snakeroot or ''sarpagandha'', contains many indole alkaloids. Medicinal uses Reserpine i ...
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Rauvolfia Amsoniifolia
''Rauvolfia'' (sometimes spelled ''Rauwolfia'') is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae. The genus is named to honor Leonhard Rauwolf. The genus can mainly be found in tropical regions of Africa, Asia, Latin America, and various oceanic islands. Spelling The International Code of Nomenclature for algae, fungi, and plants stipulates that the genus name was established by Carl Linnaeus in his 1753 book ''Species Plantarum'', which cites his earlier description which states in Botanical Latin that the name is dedicated "to Leonhard Rauwolf": "''Leon. Rauvolfio''". Although some subsequent authors hypercorrected the Classical Latin letter "v" to a modern "w", this is not accepted by the code of nomenclature. Chemical constituents '' Rauvolfia serpentina'', commonly known as Indian snakeroot or ''sarpagandha'', contains many indole alkaloids. Medicinal uses Reserpine is an alkaloid first isolated from '' R. serpent ...
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Rauvolfia Tetraphylla
''Rauvolfia tetraphylla'' is a plant in the family Apocynaceae, growing as a bush or small tree. It is commonly known as the be still tree or devil-pepper. The plant is native to Mexico, Central America, West Indies, and northern South America. It has been cultivated widely as both an ornamental and for use in traditional medicine. It is now naturalized throughout the tropics including Australasia, Indochina, and India. ''Rauvolfia tetraphylla'' fruits are called devil-peppers and hold an important position in the Indian traditional system of medicine. The plant has various significances and it is widely used by South Indian tribes. Asima Chatterjee initiated chemical investigation of alkaloids in ''Rauvolfia tetraphylla'' then known as ''Rauwolfia canescens''. Indole alkaloids including Serpentine (alkaloid), serpentine, reserpine, serpentinine, and other Rauwolfia alkaloids were identified in phytochemical study. Image Gallery File:Rauvolfia tetraphylla-devil-pepper- u ...
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Rauvolfia Afra
''Rauvolfia afra'' is a tree in the family Apocynaceae. It is commonly known as the quinine tree. These trees are distributed from the Eastern Cape of South Africa to tropical Africa and are found in low-lying forests near rivers and streams, or on floodplain A floodplain or flood plain or bottomlands is an area of land adjacent to a river. Floodplains stretch from the banks of a river channel to the base of the enclosing valley, and experience flooding during periods of high Discharge (hydrolog ...s. Taxonomy The original etymology of the species name ''caffra'' is related to kaffir, an ethnic slur used towards black people in Africa. At the July 2024 International Botanical Congress, a vote was held with the result that "''caffra''" related names will be amended to ''afra'' related ones, with this being implemented at the end of July 2024. Gallery Image:Rauvolfia_caffra_leaves_fruit.JPG, Image:Quininetree (Rauvolfia caffra) (11452988133).jpg, Image:Rauvolfia c ...
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Rauvolfia Vomitoria
''Rauvolfia vomitoria'', the poison devil's-pepper, is a plant species in the genus ''Rauvolfia''. It is native from Senegal east to Sudan and Tanzania, south to Angola; and naturalized in China, Bangladesh, different ranges of Himalayan and Puerto Rico. The plant contains a number of compounds of interest to the pharmaceutical industry and is widely used in traditional medicine. Description ''Rauvolfia vomitoria'' is a small tree or large shrub, growing to 26 ft (8m)high. The branches grow in whorls, and the leaves grow from swollen nodes in groups of three. The leaf blades are broadly lanceolate or elliptical, tapering to a long point. The small, fragrant flowers are followed by globular red fruit. All parts of the plant, except the mature wood, contain latex. Ecology This is a fast-growing tree that produces large quantities of seeds which are dispersed by birds. The seedlings and saplings are tolerant of shade and the tree regenerates after cutting or burning, soon forming d ...
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Rauvolfia Serpentina
''Rauvolfia serpentina'', the Indian snakeroot, devil pepper, serpentine wood, Sarpagandha (as known locally) or Chandrika, is a species of flower in the milkweed family Apocynaceae. It is native to the Indian subcontinent and East Asia (from India to Indonesia). ''Rauvolfia'' is a perennial undershrub widely distributed in India in the sub-Himalayan regions up to . Sarpagandha is used in folk medicine in India for centuries to treat a wide variety of maladies, including snake and insect bites, febrile conditions, malaria, abdominal pain, and dysentery. It was also used as a uterine stimulant, febrifuge, and cure for insanity. The plant was mentioned in Hindu manuscripts as long ago as 1000 BCE. Chemical composition ''Rauvolfia serpentina'' contains dozens of alkaloids of the indole alkaloid family, including ajmaline, ajmalicine, reserpine, and serpentine, among others. Research A 2016 review found that reserpine reduced systolic blood pressure (SBP) by about 8 mmHg com ...
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Apocynaceae
Apocynaceae (, from '' Apocynum'', Greek for "dog-away") is a family of flowering plants that includes trees, shrubs, herbs, stem succulents, and vines, commonly known as the dogbane family, because some taxa were used as dog poison. Notable members of the family include oleander, dogbanes, milkweeds, and periwinkles. The family is native to the European, Asian, African, Australian, and American tropics or subtropics, with some temperate members as well. The former family Asclepiadaceae (now known as Asclepiadoideae) is considered a subfamily of Apocynaceae and contains 348 genera. A list of Apocynaceae genera may be found here. Many species are tall trees found in tropical forests, but some grow in tropical dry ( xeric) environments. Also perennial herbs from temperate zones occur. Many of these plants have milky latex, and many species are poisonous if ingested, the family being rich in genera containing alkaloids and cardiac glycosides, those containing the latter oft ...
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Rauvolfia Sandwicensis
''Rauvolfia sandwicensis'', the devil's-pepper, also known as ''hao'' in the Hawaiian language, is a species of flowering plant in the milkweed family, Apocynaceae, that is endemic to Hawaii. It is a shrub, a small tree reaching in height, or, rarely, a medium-sized tree up to tall with a trunk diameter of . ''Hao'' inhabits coastal mesic and mixed mesic forests at elevations of . Significance The Hao is one of the few rare species of plant in Hawai’i along with the ''Antidesma pulvinatum'' or Hame, '' Mvoporum sandwicense'' or Naio, ''Reynoldsia sandwicensis'' or ‘Ohe, ''Santalum paniculatum'' or ‘Iliahi, '' Senna gaudichaudii'' or Kolomona, and '' Xylosma hawaiiense'' or Maua. Within all the Hawaiian Islands but Kaho’olawe, the Hao grows in dry- or shrub-land forests within lower elevations as the tree is part of the Dogbane or Apocynaceae family. The Hao does not have any known religious or cultural significance, or usefulness as forage, food, medicine, or ...
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Indole Alkaloid
Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids. History The action of some indole alkaloids has been known for ages. Aztecs used the psilocybin mushrooms which contain alkaloids psilocybin and psilocin. The flowering plant ''Rauvolfia serpentina'' which contains reserpine was a common medicine in India around 1000 BC. Africans used the roots of the perennial rainforest shrub Iboga, which contain ibogaine, as a stimulant. An infusion of Calabar bean seeds was given to people accused of crime in Nigeria: its rejection by stomach was regarded as a sign of ...
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Reserpine
Reserpine is a drug that is used for the treatment of hypertension, high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces mortality of people with hypertension. Although the use of reserpine as a solo drug has declined since it was first approved by the FDA in 1955, the combined use of reserpine and a thiazide diuretic or vasodilator is still recommended in patients who do not achieve adequate lowering of blood pressure with first-line drug treatment alone. The reserpine-hydrochlorothiazide combo pill was the 17th most commonly prescribed of the 43 combination antihypertensive pills available in 2012. The antihypertensive actions of reserpine are largely due to its antinoradrenergic effects, which are a result of its ability to deplete catecholamines (among other monoamine neurotransmitters) from peripheral nervous system, peripheral sympathetic ...
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Leonhard Rauwolf
Leonhard Rauwolf (also spelled Leonhart Rauwolff) (21 June 1535 – 15 September 1596) was a German physician, botanist, and traveller. His main notability arises from a trip he made through the Levant and Mesopotamia in 1573–75. The motive of the trip was to search for herbal medicine supplies. Shortly after he returned, he published a set of new botanical descriptions with an herbarium. Later he published a general travel narrative about his visit. Early years The young Rauwolff studied initially at University of Wittenberg and then studied botany and medicine at two universities in southern France, University of Montpellier and University of Valence. He was a pupil of Guillaume Rondelet in Montpellier in 1560. In 1564 he had the benefit of visiting the renowned botanist Carolus Clusius (who once had been a student of Rondelet too). In 1565 he set up a medical practice in his hometown, Augsburg, in Bavaria. In that year he married. Travel through Levant and Mesopotamia Rauw ...
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Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ...
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