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RAP2A
Ras-related protein Rap-2a is a protein that in humans is encoded by the ''RAP2A'' gene. RAP2A is a member of the Ras-related protein family. Interactions RAP2A has been shown to interact with RUNDC3A, RASSF5 and RALGDS Ral guanine nucleotide dissociation stimulator is a protein that is encoded by the ''RALGDS'' gene in humans. Interactions RALGDS has been shown to interact with: * Arrestin beta 1, * Arrestin beta 2, * HRAS, * KRAS, * MRAS, * RAP1A, * .... References Further reading * * * * * * * * * * * * * * * * * {{gene-13-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rap GTP-binding Protein
Rap GTP-binding protein also known as Ras-related proteins or simply RAP is a type of small GTPase, similar in structure to Ras. These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. RAP counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Family members Human genes that encode Ras-related proteins include: * RAP1A, RAP1B Ras-related protein Rap-1b, also known as GTP-binding protein smg p21B, is a protein that in humans is encoded by the ''RAP1B'' gene In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian u ... * RAP2A, RAP2B, RAP1C * RAB5C References External links * EC 3.6.5 Peripheral membrane ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RUNDC3A
RUN domain-containing protein 3A is a protein that in humans is encoded by the ''RUNDC3A'' gene. Interactions RUNDC3A has been shown to interact with RAP2A Ras-related protein Rap-2a is a protein that in humans is encoded by the ''RAP2A'' gene. RAP2A is a member of the Ras-related protein family. Interactions RAP2A has been shown to interact with RUNDC3A, RASSF5 and RALGDS Ral guanine nucleotid .... See also * RUN domain References Further reading * * * * * * {{gene-17-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RASSF5
Ras association domain-containing protein 5 is a protein that in humans is encoded by the ''RASSF5 or F5'' gene. Function This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. Interactions RASSF5 has been shown to interact Advocates for Informed Choice, dba interACT or interACT Advocates for Intersex Youth, is a 501(c)(3) nonprofit organization using innovative strategies to advocate for the legal and human rights of children with intersex traits. The organizat ... with RRAS, RAP2A, MRAS and RASSF1. References Further readi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid resid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
