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Quinolizidine
Quinolizidine (norlupinane, octahydro-2''H''-quinolizine) is a nitrogen-containing heterocyclic compound. Some alkaloids (e.g. cytisine and sparteine) are derivatives of quinolizidine. Quinolizidine alkaloids Quinolizidine alkaloids, such as nupharine and related chemicals, can be found in ''Nymphaea lotus'' and other species in the family Nymphaeaceae. Quinolizidine alkaloids are also found in genistoid legumes A legume () is a plant in the family Fabaceae (or Leguminosae), or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock fo .... External links * * Synthesis: {{heterocyclic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sparteine
Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in ''Lupinus mutabilis'', and is thought to chelate the bivalent cations calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughan Williams classification of antiarrhythmic drugs. It is also used as a chiral ligand in organic chemistry, especially in syntheses involving organolithium reagents. Biosynthesis Sparteine is a lupin alkaloid containing a tetracyclic bis-quinolizidine ring system derived from three C5 chains of lysine, or more specifically, L-lysine. The first intermediate in the biosynthesis is cadaverine, the decarboxylation product of lysine catalyzed by the enzyme lysine decarboxylase (LDC). Three units of cadaverine are used to form the quinolizidine skeleton. The mechanism of formation has been studied enzymatically, as well as with ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alkaloid
Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.Chemical Encyclopedia: alkaloids xumuk.ru Alkaloids are produced by a large variety of organisms including , , Medicinal plant, plants, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytisine
Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as ''Laburnum'' and ''Cytisus'' of the family Fabaceae. It has been used medically to help with smoking cessation. Although widely used for smoking cessation in Eastern Europe, cytisine remains relatively unknown beyond it. However, it has been found effective in several randomized clinical trials, including some in the United States and a large one in New Zealand, and is being investigated in additional trials in the United States (being conducted by Achieve Life Sciences) and a non-inferiority trial in Australia in which it is being compared head-to-head with the smoking cessation aid varenicline (sold in the United States as Chantix). It has also been used entheogenically via mescalbeans by some Native American groups, historically in the Rio Grande Valley predating even peyote. Sources Cytisine is extracted from the seeds of ''Cytisus la ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterocyclic Compound
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of these heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of heterocyclic chemistry focuses especially on unsaturated derivatives, and the preponderance of work and applications involves unstrained 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of pyridine, thiophene, pyrrole, and furan are quinol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nymphaea Lotus
''Nymphaea lotus'', the white Egyptian lotus, tiger lotus, white lotus or Egyptian white water-lily, is a flowering plant of the family Nymphaeaceae. Distribution It grows in various parts of East Africa and Southeast Asia. The ''Nymphaea lotus'' var. ''thermalis'' is a Tertiary relict variety endemic to the thermal waters of Europe, for example the Peţa River in Romania or the Hévíz lake in Hungary . Cultivation It was introduced into Western cultivation in 1802 by Loddiges Nursery. Eduard Ortgies crossed ''Nymphaea lotus'' (''N. dentata'') with ''Nymphaea pubescens'' (''N. rubra'') to produce the first '' Nymphaea'' hybrid, illustrated in ''Flore des serres'' 8 t. 775, 776 under the name ''Nymphaea ortgiesiano-rubra''. It is a popular ornamental aquatic plant in Venezuela. Description This species of water lily has lily pads which float on the water and blossoms which rise above the water. It is a perennial, growing to 45 cm in height. The flower is white, someti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genistoids
The Genistoids are one of the major radiations in the plant family Fabaceae. Members of this phylogenetic clade are primarily found in the Southern hemisphere. Some genera are pollinated by birds. The genistoid clade is consistently resolved as monophyletic in molecular phylogenetic analyses. It is estimated to have arisen 56.4 ± 0.2 million years ago (in the Paleocene). A node-based definition for the genistoids is: "the MRCA of '' Poecilanthe parviflora'' and ''Lupinus argenteus''." One morphological synapomorphy has been tentatively identified: production of quinolizidine alkaloids. Some genera also accumulate pyrrolizidine. A new genus, to be segregated from '' Clathrotropis'', has also been proposed to occupy an undetermined position within the genistoid clade. Core Genistoids The core genistoids, also known as the genistoids ''sensu stricto'', comprise most of the tribes of the genistoids ''sensu lato'', and are found mainly in Africa and Eurasia. This subclade is al ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Legumes
A legume () is a plant in the family Fabaceae (or Leguminosae), or the fruit or seed of such a plant. When used as a dry grain, the seed is also called a pulse. Legumes are grown agriculturally, primarily for human consumption, for livestock forage and silage, and as soil-enhancing green manure. Well-known legumes include beans, soybeans, chickpeas, peanuts, lentils, lupins, mesquite, carob, tamarind, alfalfa, and clover. Legumes produce a botanically unique type of fruit – a simple dry fruit that develops from a simple carpel and usually dehisces (opens along a seam) on two sides. Legumes are notable in that most of them have symbiotic nitrogen-fixing bacteria in structures called root nodules. For that reason, they play a key role in crop rotation. Terminology The term ''pulse'', as used by the United Nations' Food and Agriculture Organization (FAO), is reserved for legume crops harvested solely for the dry seed. This excludes green beans and green peas, which ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
