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Promethease
SNPedia (pronounced "snipedia") is a wiki-based bioinformatics web site that serves as a database of single nucleotide polymorphisms (SNPs). Each article on a SNP provides a short description, links to scientific articles and personal genomics web sites, as well as microarray information about that SNP. Thus SNPedia may support the interpretation of results of personal genotyping from, e.g., 23andMe and similar companies. SNPedia is a semantic wiki, powered by MediaWiki and the Semantic MediaWiki extension. SNPedia was created, and is run by, geneticist Greg Lennon and programmer Mike Cariaso, who at the time of the site's founding were both located in Bethesda, Maryland. , the website has 537 medical conditions and 109,729 SNPs in its database. The number of SNPs in SNPedia has doubled roughly once every 14 months since August 2007. On 7 September 2019, MyHeritage announced that they acquired both SNPedia and Promethease. All non-European raw genetic data files previously uplo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
SNPedia
SNPedia (pronounced "snipedia") is a wiki-based bioinformatics web site that serves as a database of single nucleotide polymorphisms (SNPs). Each article on a SNP provides a short description, links to scientific articles and personal genomics web sites, as well as microarray information about that SNP. Thus SNPedia may support the interpretation of results of personal genotyping from, e.g., 23andMe and similar companies. SNPedia is a semantic wiki, powered by MediaWiki and the Semantic MediaWiki extension. SNPedia was created, and is run by, geneticist Greg Lennon and programmer Mike Cariaso, who at the time of the site's founding were both located in Bethesda, Maryland. , the website has 537 medical conditions and 109,729 SNPs in its database. The number of SNPs in SNPedia has doubled roughly once every 14 months since August 2007. On 7 September 2019, MyHeritage announced that they acquired both SNPedia and Promethease. All non-European raw genetic data files previously uploa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MyHeritage
MyHeritage is an online genealogy platform with web, mobile, and software products and services, introduced by the Israeli company MyHeritage in 2003. Users of the platform can obtain their family trees, upload and browse through photos, and search through over 14 billion historical records, among other features. As of 2020, the service supports 42 languages and has more than 50 million users worldwide who have built around 52 million family trees. In 2016, it launched a genetic testing service called MyHeritage DNA. The company is headquartered in Or Yehuda, Israel, with additional offices in Tel Aviv, Israel, Lehi, Utah, Kyiv, Ukraine, and Burbank, California. History 2003–2007: Foundation and early years MyHeritage was founded in 2003 by Israeli entrepreneur Gilad Japhet (who continues to serve as the company's CEO). Japhet started the company from his living room in Bnei Atarot, Israel. For a long time, the company's headquarters were located in a family farmhouse in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Semantic Wikis
Semantics (from grc, σημαντικός ''sēmantikós'', "significant") is the study of reference, meaning, or truth. The term can be used to refer to subfields of several distinct disciplines, including philosophy, linguistics and computer science. History In English, the study of meaning in language has been known by many names that involve the Ancient Greek word (''sema'', "sign, mark, token"). In 1690, a Greek rendering of the term ''semiotics'', the interpretation of signs and symbols, finds an early allusion in John Locke's ''An Essay Concerning Human Understanding'': The third Branch may be called [''simeiotikí'', "semiotics"], or the Doctrine of Signs, the most usual whereof being words, it is aptly enough termed also , Logick. In 1831, the term is suggested for the third branch of division of knowledge akin to Locke; the "signs of our knowledge". In 1857, the term ''semasiology'' (borrowed from German ''Semasiologie'') is attested in Josiah W. Gibbs' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MediaWiki Websites
MediaWiki is a free and open-source wiki software. It is used on Wikipedia and almost all other Wikimedia websites, including Wiktionary, Wikimedia Commons and Wikidata; these sites define a large part of the requirement set for MediaWiki. It was developed for use on Wikipedia in 2002, and given the name "MediaWiki" in 2003. MediaWiki was originally developed by Magnus Manske and improved by Lee Daniel Crocker. Magnus Manske's announcement of "PHP Wikipedia", wikipedia-l, August 24, 2001 Its development has since then been coordinated by the Wikimedia Foundation. MediaWiki is written in the PHP programming language and stores all text content into a database. The software is optimized to efficiently handle large projects, which can have terabytes of content and hundreds of thousands of views per second. Because Wikipedia is one of the world's largest websites, achieving scalability through multiple layers of caching and database replication has been a major concern fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genomics Companies
Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advances in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Webcast
A webcast is a media presentation distributed over the Internet using streaming media technology to distribute a single content source to many simultaneous listeners/viewers. A webcast may either be distributed live or on demand. Essentially, webcasting is "broadcasting" over the Internet. The largest "webcasters" include existing radio and TV stations, who "simulcast" their output through online TV or online radio streaming, as well as a multitude of Internet-only "stations". Webcasting usually consists of providing non-interactive linear streams or events. Rights and licensing bodies offer specific "webcasting licenses" to those wishing to carry out Internet broadcasting using copyrighted material. Overview Webcasting is used extensively in the commercial sector for investor relations presentations (such as annual general meetings), in e-learning (to transmit seminars), and for related communications activities. However, webcasting does not bear much, if any, relationship to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Full Genome Sequencing
Whole genome sequencing (WGS), also known as full genome sequencing, complete genome sequencing, or entire genome sequencing, is the process of determining the entirety, or nearly the entirety, of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of gene sequencing at SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. Whole genome sequencing should not be confused with DNA pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Online Mendelian Inheritance In Man
Online Mendelian Inheritance in Man (OMIM) is a continuously updated catalog of human genes and genetic disorders and traits, with a particular focus on the gene-phenotype relationship. , approximately 9,000 of the over 25,000 entries in OMIM represented phenotypes; the rest represented genes, many of which were related to known phenotypes. Versions and history OMIM is the online continuation of Dr. Victor A. McKusick's ''Mendelian Inheritance in Man'' (MIM), which was published in 12 editions between 1966 and 1998.McKusick, V. A. ''Mendelian Inheritance in Man. Catalogs of Autosomal Dominant, Autosomal Recessive and X-Linked Phenotypes.'' Baltimore, MD: Johns Hopkins University Press, 1st ed, 1996; 2nd ed, 1969; 3rd ed, 1971; 4th ed, 1975; 5th ed, 1978; 6th ed, 1983; 7th ed, 1986; 8th ed, 1988; 9th ed, 1990; 10th ed, 1992. Nearly all of the 1,486 entries in the first edition of MIM discussed phenotypes. MIM/OMIM is produced and curated at the Johns Hopkins School of Medici ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DbSNP
The Single Nucleotide Polymorphism Database (dbSNP) is a free public archive for genetic variation within and across different species developed and hosted by the National Center for Biotechnology Information (NCBI) in collaboration with the National Human Genome Research Institute (NHGRI). Although the name of the database implies a collection of one class of polymorphisms only (i.e., single nucleotide polymorphisms (SNPs)), it in fact contains a range of molecular variation: (1) SNPs, (2) short deletion and insertion polymorphisms ( indels/DIPs), (3) microsatellite markers or short tandem repeats (STRs), (4) multinucleotide polymorphisms (MNPs), (5) heterozygous sequences, and (6) named variants. The dbSNP accepts apparently neutral polymorphisms, polymorphisms corresponding to known phenotypes, and regions of no variation. It was created in September 1998 to supplement GenBank, NCBI’s collection of publicly available nucleic acid and protein sequences. In 2017, NCBI stopped ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reason (magazine)
''Reason'' is an American libertarian monthly magazine published by the Reason Foundation. The magazine has a circulation of around 50,000 and was named one of the 50 best magazines in 2003 and 2004 by the ''Chicago Tribune''. History ''Reason'' was founded in 1968 by Lanny Friedlander (1947–2011), a student at Boston University, as a more-or-less monthly mimeographed publication. In 1970 it was purchased by Robert W. Poole Jr., Manuel S. Klausner, and Tibor R. Machan, who set it on a more regular publishing schedule. As the monthly print magazine of "free minds and free markets", it covers politics, culture, and ideas with a mix of news, analysis, commentary, and reviews. During the 1970s and 80s, the magazine's contributors included Milton Friedman, Murray Rothbard, Thomas Szasz, and Thomas Sowell. In 1978, Poole, Klausner, and Machan created the associated Reason Foundation, in order to expand the magazine's ideas into policy research. Marty Zupan joined ''Reason'' in 197 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
