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Patellar Reflex
The patellar reflex, also called the knee reflex or knee-jerk, is a stretch reflex which tests the L2, L3, and L4 segments of the spinal cord. Mechanism Striking of the patellar tendon with a reflex hammer just below the patella stretches the muscle spindle in the quadriceps muscle. This produces a signal which travels back to the spinal cord and synapses (without interneurons) at the level of L3 or L4 in the spinal cord, completely independent of higher centres. From there, an alpha motor neuron conducts an efferent impulse back to the quadriceps femoris muscle, triggering contraction. This contraction, coordinated with the relaxation of the antagonistic flexor hamstring muscle causes the leg to kick. There is a latency of around 18 ms between stretch of the patellar tendon and the beginning of contraction of the quadriceps femoris muscle. This is a reflex of proprioception which helps maintain posture and balance, allowing to keep one's balance with little effort or cons ...
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Interneuron
Interneurons (also called internuncial neurons, relay neurons, association neurons, connector neurons, intermediate neurons or local circuit neurons) are neurons that connect two brain regions, i.e. not direct motor neurons or sensory neurons. Interneurons are the central nodes of neural circuits, enabling communication between sensory or motor neurons and the central nervous system (CNS). They play vital roles in reflexes, neuronal oscillations, and neurogenesis in the adult mammalian brain. Interneurons can be further broken down into two groups: local interneurons and relay interneurons. Local interneurons have short axons and form circuits with nearby neurons to analyze small pieces of information. Relay interneurons have long axons and connect circuits of neurons in one region of the brain with those in other regions. However, interneurons are generally considered to operate mainly within local brain areas. The interaction between interneurons allow the brain to perform ...
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The Coshocton Tribune
''Coshocton Tribune'' is a daily newspaper that serves the community of Coshocton, Ohio, United States, and the surrounding Coshocton County. History The ''Coshocton Tribune'' was founded in 1909 by William J. Bahmer, a former teacher. The paper was independently owned until 1960, when it was sold to Thompson Newspapers. In 2000, it was sold to Gannett Gannett Co., Inc. () is an American mass media holding company headquartered in McLean, Virginia, in the Washington, D.C., metropolitan area.


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Physiology
Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical and physical functions in a living system. According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. ''Physiological state'' is the condition of normal function. In contrast, '' pathological state'' refers to abnormal conditions, including human diseases. The Nobel Prize in Physiology or Medicine is awarded by the Royal Swedish Academy of Sciences for exceptional scientific achievements in physiology related to the field of medicine. Foundations Cells Although there a ...
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Michael Foster (physiologist)
Sir Michael Foster (8 March 1836 – 29 January 1907) was an English physiologist. He was instrumental in organizing the Cambridge Biological School and acted as Secretary of the Royal Society. Biography Foster was born in Huntingdon, Huntingdonshire, in March 1836, the son of Michael Foster, FRCS. He was educated at Huntingdon Grammar school and University College School, London. After graduating in medicine in 1859, he began to practise in his native town, but in 1867 he returned to London as teacher of practical physiology at University College London, where two years afterwards he became professor. In 1870 he was appointed by Trinity College, Cambridge, to its praelectorship in physiology, and thirteen years later he became the first occupant of the newly created chair of physiology in the university, holding it till 1903. One of his most famous students at Cambridge was Charles Scott Sherrington who went on to win the Nobel Prize in 1932. He married first, in 1864, Geo ...
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Carl Friedrich Westphal
Carl may refer to: * Carl, Georgia, city in USA * Carl, West Virginia, an unincorporated community *Carl (name), includes info about the name, variations of the name, and a list of people with the name * Carl², a TV series * "Carl", an episode of television series ''Aqua Teen Hunger Force'' * An informal nickname for a student or alum of Carleton College CARL may refer to: * Canadian Association of Research Libraries * Colorado Alliance of Research Libraries See also *Carle (other) *Charles *Carle, a surname * Karl (other) *Karle (other) Karle may refer to: Places * Karle (Svitavy District), a municipality and village in the Czech Republic * Karli, India, a town in Maharashtra, India ** Karla Caves, a complex of Buddhist cave shrines * Karle, Belgaum, a settlement in Belgaum di ... {{disambig ja:カール zh:卡尔 ...
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Wilhelm Heinrich Erb
Wilhelm Heinrich Erb (30 November 1840 – 29 October 1921) was a German neurologist. He was born in Winnweiler, and died in Heidelberg. Academic career In 1864 he received his medical degree from the University of Heidelberg, where for several years he served as an assistant to pathologist Nikolaus Friedreich (1825-1882). As a young man, he also worked for a period of time under Ludwig von Buhl (1816-1880) in Munich. In 1880 Erb attained the chair of special pathology at the University of Leipzig, where he was also appointed head of its policlinic. In 1883 he succeeded Friedreich at the University of Heidelberg, where he worked until his retirement in 1907. Psychiatrist Emil Kraepelin (1856-1926) and neurologists Ernst Julius Remak (1849-1911), Max Nonne (1861-1959) and Paul Julius Möbius (1853–1907)
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Infant
An infant or baby is the very young offspring of human beings. ''Infant'' (from the Latin word ''infans'', meaning 'unable to speak' or 'speechless') is a formal or specialised synonym for the common term ''baby''. The terms may also be used to refer to juveniles of other organisms. A newborn is, in colloquial use, an infant who is only hours, days, or up to one month old. In medical contexts, a newborn or neonate (from Latin, ''neonatus'', newborn) is an infant in the first 28 days after birth; the term applies to premature, full term, and postmature infants. Before birth, the offspring is called a fetus. The term ''infant'' is typically applied to very young children under one year of age; however, definitions may vary and may include children up to two years of age. When a human child learns to walk, they are called a toddler instead. Other uses In British English, an '' infant school'' is for children aged between four and seven. As a legal term, ''infancy'' is more ...
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Hyperthyroidism
Hyperthyroidism is the condition that occurs due to excessive production of thyroid hormones by the thyroid gland. Thyrotoxicosis is the condition that occurs due to excessive thyroid hormone of any cause and therefore includes hyperthyroidism. Some, however, use the terms interchangeably. Signs and symptoms vary between people and may include irritability, muscle weakness, sleeping problems, a fast heartbeat, heat intolerance, diarrhea, enlargement of the thyroid, hand tremor, and weight loss. Symptoms are typically less severe in the elderly and during pregnancy. An uncommon complication is thyroid storm in which an event such as an infection results in worsening symptoms such as confusion and a high temperature and often results in death. The opposite is hypothyroidism, when the thyroid gland does not make enough thyroid hormone. Graves' disease is the cause of about 50% to 80% of the cases of hyperthyroidism in the United States. Other causes include multinodu ...
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Upper Motor Neuron Lesion
An upper motor neuron lesion (also known as pyramidal insufficiency) Is an injury or abnormality that occurs in the neural pathway above the anterior horn cell of the spinal cord or motor nuclei of the cranial nerves. Conversely, a lower motor neuron lesion affects nerve fibers traveling from the anterior horn of the spinal cord or the cranial motor nuclei to the relevant muscle(s). Upper motor neuron lesions occur in the brain or the spinal cord as the result of stroke, multiple sclerosis, traumatic brain injury, cerebral palsy, atypical parkinsonisms, multiple system atrophy, and amyotrophic lateral sclerosis. Symptoms Changes in muscle performance can be broadly described as the upper motor neuron syndrome. These changes vary depending on the site and the extent of the lesion, and may include: * Muscle weakness. known as 'pyramidal weakness' * Decreased control of active movement, particularly slowness * Spasticity, a velocity-dependent change in muscle tone * Clas ...
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Cerebellar Diseases
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebellum plays an important role in motor control. It may also be involved in some cognitive functions such as attention and language as well as emotional control such as regulating fear and pleasure responses, but its movement-related functions are the most solidly established. The human cerebellum does not initiate movement, but contributes to coordination, precision, and accurate timing: it receives input from sensory systems of the spinal cord and from other parts of the brain, and integrates these inputs to fine-tune motor activity. Cerebellar damage produces disorders in fine movement, equilibrium, posture, and motor learning in humans. Anatomically, the human cerebellum has the appearance of a separate structure attached to the b ...
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Lower Motor Neuron Lesion
A lower motor neuron lesion is a lesion which affects nerve fibers traveling from the lower motor neuron(s) in the anterior horn/ anterior grey column of the spinal cord, or in the motor nuclei of the cranial nerves, to the relevant muscle(s). One major characteristic used to identify a lower motor neuron lesion is flaccid paralysis – paralysis accompanied by loss of muscle tone. This is in contrast to an upper motor neuron lesion, which often presents with spastic paralysis – paralysis accompanied by severe hypertonia. Signs and symptoms * Muscle paresis or paralysis * Fibrillations * Fasciculations – caused by increased receptor concentration on muscles to compensate for lack of innervation. * Hypotonia or atonia – Tone is not velocity dependent. * Hyporeflexia - Along with deep reflexes even cutaneous reflexes are also decreased or absent. * Strength – weakness is limited to segmental or focal pattern, Root innervated pattern The extensor plantar refle ...
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