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Pierre Eugène Ménétrier
Pierre Eugène Ménétrier (7 December 1859 – 22 August 1935) was a French pathologist from Paris. He is remembered for his description of a rare gastric disorder that was later to become known as Ménétrier's disease. In 1888 Ménétrier first described the disorder while performing post-mortem studies, noticing hyperplastic changes of the gastric mucosa in cadavers. At the time, he named the disease ''polyadenomes en nappe''. Although Ménétrier understood the debilitative factors of the disease, it wouldn't be until years later that the associated protein-losing enteropathic aspects of the disorder were realized. Other names for "Ménétrier's disease" are "hyperplastic hypersecretory gastropathy" and "giant hypertrophic gastritis". He published his findings in a treatise titled ''Des polyadenomes gastriques et de leurs rapports avec le cancer de l’estomac''. Ménétrier published writings on Byzantine and Greco-Roman medicine, and was a member of the International S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathologist
Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area that includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue and human cell samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"). The suffix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomyopathy) and psychological conditions (such as ps ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paris
Paris () is the Capital city, capital and List of communes in France with over 20,000 inhabitants, largest city of France. With an estimated population of 2,048,472 residents in January 2025 in an area of more than , Paris is the List of cities in the European Union by population within city limits, fourth-most populous city in the European Union and the List of cities proper by population density, 30th most densely populated city in the world in 2022. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, culture, Fashion capital, fashion, and gastronomy. Because of its leading role in the French art, arts and Science and technology in France, sciences and its early adoption of extensive street lighting, Paris became known as the City of Light in the 19th century. The City of Paris is the centre of the Île-de-France region, or Paris Region, with an official estimated population of 12,271,794 inhabitants in January 2023, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ménétrier's Disease
Ménétrier disease is a rare, acquired, premalignant disease of the stomach characterized by massive gastric folds, gastric hyperplasia, excessive mucus production with resultant Hypoalbuminemia, protein loss, and little or no Stomach acid, acid production (achlorhydria). The disorder is associated with excessive secretion of transforming growth factor alpha (TGF-α). It is named after French physician Pierre Eugène Ménétrier (1859–1935). Signs and symptoms Individuals with the disease present with upper abdominal (epigastric) pain, at times accompanied by nausea, vomiting, Anorexia (symptom), loss of appetite, Peripheral edema, edema, weakness, and weight loss. A small amount of gastrointestinal bleeding may occur, which is typically due to superficial mucosal erosions; large volume bleeding is rare. 20% to 100% of patients, depending on time of presentation, develop a Protein losing enteropathy, protein-losing gastropathy accompanied by hypoalbuminemia, low blood albumi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperplasia
Hyperplasia (from ancient Greek ὑπέρ ''huper'' 'over' + πλάσις ''plasis'' 'formation'), or hypergenesis, is an enlargement of an organ or tissue caused by an increase in the amount of Tissue (biology), organic tissue that results from cell proliferation. It may lead to the Gross anatomy, gross enlargement of an organ, and the term is sometimes confused with benign neoplasia or benign tumor. Hyperplasia is a common preneoplastic response to stimulus. Microscopically, cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). Hyperplasia is different from hypertrophy in that the Cellular adaptation, adaptive cell change in hypertrophy is an increase in the cell size, ''size'' of cells, whereas hyperplasia involves an increase in the ''number'' of cells. Causes Hyperplasia may be due to any number of causes, including proliferation of basal layer of epidermis to compensate skin loss, Chronic inflammation, chr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastric Mucosa
The gastric mucosa is the mucous membrane layer of the stomach, which contains the gastric pits, to which the gastric glands empty. In humans, it is about one mm thick, and its surface is smooth, soft, and velvety. It consists of simple secretory columnar epithelium, an underlying supportive layer of loose connective tissue called the lamina propria, and the muscularis mucosae, a thin layer of muscle that separates the mucosa from the underlying submucosa. Description In its fresh state, it is of a pinkish tinge at the pyloric end and of a red or reddish-brown color over the rest of its surface. In infancy it is of a brighter hue, the vascular redness being more marked. It is thin at the cardiac extremity, but thicker toward the pylorus. During the contracted state of the stomach it is thrown into numerous folds or rugae, which, for the most part, have a longitudinal direction. They are most marked toward the pyloric end of the stomach, and along the greater curvature, and are e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cadaver
A cadaver, often known as a corpse, is a Death, dead human body. Cadavers are used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue (biology), tissue to repair a defect in a living human being. Students in medical school study and dissect cadavers as a part of their education. Others who study cadavers include archaeologists and arts students. In addition, a cadaver may be used in the development and evaluation of surgical instruments. The term ''cadaver'' is used in courts of law (and, to a lesser extent, also by media outlets such as newspapers) to refer to a dead body, as well as by recovery teams searching for bodies in natural disasters. The word comes from the Latin word ''cadere'' ("to fall"). Related terms include ''cadaverous'' (resembling a cadaver) and ''cadaveric spasm'' (a muscle spasm causing a dead body to twitch or jerk). A cadaver graft (also called “postmortem graft”) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Losing Enteropathy
Protein losing enteropathy (PLE) is a syndrome in which Blood protein, blood proteins are lost excessively via the gastrointestinal tract, gastrointestinal (GI) tract. It may be caused by many different underlying diseases that damage the lining of the GI tract (Mucous membrane, mucosa) or cause blockage of its Lymphatic system, lymphatic drainage. Signs and symptoms The signs and symptoms of protein losing enteropathy include diarrhea, fever, and general abdominal discomfort. Swelling of the legs due to peripheral edema can also occur; however, if the PLE is related to a systemic disease such as congestive heart failure or constrictive pericarditis, then these symptoms could be due directly to the underlying illness. In severe cases, anasarca, a generalized form of edema, may develop. Causes The causes of protein-losing enteropathy can include GI conditions (among other causes), like the following: Mechanism The pathophysiology of protein losing enteropathy is a result of pla ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gastritis
Gastritis is the inflammation of the lining of the stomach. It may occur as a short episode or may be of a long duration. There may be no symptoms but, when symptoms are present, the most common is upper abdominal pain (see dyspepsia). Other possible symptoms include nausea and vomiting, bloating, loss of appetite and heartburn. Complications may include stomach bleeding, stomach ulcers, and stomach tumors. When due to autoimmune problems, low red blood cells due to not enough vitamin B12 may occur, a condition known as pernicious anemia. Common causes include infection with '' Helicobacter pylori'' and use of nonsteroidal anti-inflammatory drugs ( NSAIDs). When caused by ''H. pylori'' this is now termed ''Helicobacter pylori'' induced gastritis, and included as a listed disease in ICD11. Less common causes include alcohol, smoking, cocaine, severe illness, autoimmune problems, radiation therapy and Crohn's disease. Endoscopy, a type of X-ray known as an upper gast ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Byzantine Medicine
Byzantine medicine encompasses the common medical practices of the Byzantine Empire from c. 400 AD to 1453 AD. Byzantine medicine was notable for building upon the knowledge base developed by its Greco-Roman predecessors. In preserving medical practices from antiquity, Byzantine medicine influenced Islamic medicine and fostered the Western rebirth of medicine during the Renaissance. The concept of the hospital appeared in Byzantine Empire as an institution to offer medical care and possibility of a cure for the patients because of the ideals of Christian charity. Byzantine physicians often compiled and standardized medical knowledge into textbooks. Their records tended to include both diagnostic explanations and technical drawings. The Medical Compendium in Seven Books, written by the leading physician Paul of Aegina, survived as a particularly thorough source of medical knowledge. This compendium, written in the late seventh century, remained in use as a standard textbook for th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society For The History Of Medicine
The International Society for the History of Medicine is a non profit international society devoted to the academic study of the history of medicine, including the organization of international congresses. The Society was founded in 1920 in Belgium. The society is present in 50 countries, holds delegations in 38 countries, and has about 800 members. It is affiliated with national societies in many countries, among which are Argentina, Australia, Belgium, Brazil, Canada, Chile, China, Finland, France, Georgia, Germany, Greece, Italy, Latvia, Mexico, Morocco, Portugal, Romania, Spain, Tunisia, Turkey, the United States, and the United Kingdom. Membership is open to both physicians and historians. International congresses The society holds a biennial International Congress, and, beginning in 2001, an international meeting in the years the main conference is not held. Communications to the international congresses are peer reviewed.Brief of the Globe Foundations,vol 13: " 1990, to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lisieux
Lisieux () is a Communes of France, commune in the Calvados (department), Calvados Departments of France, department in the Normandy (administrative region), Normandy Regions of France, region in northwestern France. It is the capital of the Pays d'Auge area, which is characterised by valleys and hedged farmland. Name The name of the town derives from the ("Noviomagus of the Lexovii"). The town was originally known in Common Celtic, Celtic as ("New Field", "New Market"), which was Latinization of names, Latinized as . Owing to the large number of similarly named cities, however, it was necessary to specify where this one was located. The local French demonym derives from the Latin as well. History Antiquity Lisieux was the capital of the Lexovii. In his work, ''Commentaries on the Gallic War'', Caesar mentions a Gallic ''oppidum'', a term which refers to Celtic towns located on the tops of hills. The oppidum has been pinpointed to a place referred to as ''le Castellier op ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1859 Births
Events January–March * January 21 – José Mariano Salas (1797–1867) becomes Conservative interim President of Mexico. * January 24 ( O. S.) – Under the rule of Alexandru Ioan Cuza, the provinces of Wallachia and Moldavia are united under the jurisdiction of the Ottoman Empire. It would be a principal step in forming the modern state of Romania. * January 28 – The city of Olympia is incorporated in the Washington Territory of the United States of America. * February 2 – Miguel Miramón (1832–1867) becomes Conservative interim President of Mexico. * February 4 – German scholar Constantin von Tischendorf rediscovers the '' Codex Sinaiticus'', a 4th-century uncial manuscript of the Greek Bible, in Saint Catherine's Monastery on the foot of Mount Sinai, in the Khedivate of Egypt and arranges for its presentation to his patron, Tsar Alexander II of Russia at Saint Petersburg. * February 14 – Oregon is admitted as the 33rd U.S. state. * February 12 – ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
