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Pharmacologist
Pharmacology is the science of drugs and medications, including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals. The field encompasses drug composition and properties, functions, sources, synthesis and drug design, molecular and cellular mechanisms, organ/systems mechanisms, signal transduction/cellular communication, molecular diagnostics, interactions, chemical biology, therapy, and medical applications and antipathogenic capabilities. The two main areas of pharmacology are pharmacodynamics and pharmacokinetics. Pharmacodynamics studies the effects of a drug on biological systems, and pharmacokinetics studies the effects of biological systems on a drug. In broad terms, pharmacodynamics ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacodynamics
Pharmacodynamics (PD) is the study of the biochemistry, biochemical and physiology, physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Constant Tempertature Bath For Isolated Organs Wellcome M0013241
Constant or The Constant may refer to: Mathematics * Constant (mathematics), a non-varying value * Mathematical constant, a special number that arises naturally in mathematics, such as pi, or Other concepts * Control variable or scientific constant, in experimentation the unchanging or constant variable * Physical constant, a physical quantity generally believed to be universal and unchanging * Constant (computer programming), a value that, unlike a variable, cannot be reassociated with a different value * Logical constant, a symbol in symbolic logic that has the same meaning in all models, such as the symbol "=" for "equals" People * Constant (given name) * Constant (surname) * John, Elector of Saxony (1468–1532), known as John the Constant * Constant Nieuwenhuys (1920-2005), better known as Constant Places * Constant, Barbados, a populated place Arts and entertainment * "The Constant", a 2008 episode of the television show ''Lost'' * The Constant (Story of the Year a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient Greek
Ancient Greek (, ; ) includes the forms of the Greek language used in ancient Greece and the classical antiquity, ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Greek Dark Ages, Dark Ages (), the Archaic Greece, Archaic or Homeric Greek, Homeric period (), and the Classical Greece, Classical period (). Ancient Greek was the language of Homer and of fifth-century Athens, fifth-century Athenian historians, playwrights, and Ancient Greek philosophy, philosophers. It has contributed many words to English vocabulary and has been a standard subject of study in educational institutions of the Western world since the Renaissance. This article primarily contains information about the Homeric Greek, Epic and Classical periods of the language, which are the best-attested periods and considered most typical of Ancient Greek. From the Hellenistic period (), Ancient Greek was followed by Koine Greek, which is regar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Raw Opium
Opium (also known as poppy tears, or Lachryma papaveris) is the dried latex obtained from the seed capsules of the opium poppy ''Papaver somniferum''. Approximately 12 percent of opium is made up of the analgesic alkaloid morphine, which is processed chemically to produce heroin and other synthetic opioids for medicinal use and for the illegal drug trade. Opium's main psychoactive alkaloids, primarily morphine, act on μ-opioid receptors, causing analgesia and addiction with long-term use leading to tolerance, dependence, and increased cancer risk. The latex also contains the closely related opiates codeine and thebaine, and non-analgesic alkaloids such as papaverine and noscapine. The traditional, labor-intensive method of obtaining the latex is to scratch ("score") the immature seed pods (fruits) by hand; the latex leaks out and dries to a sticky yellowish residue that is later scraped off and dehydrated. The English word for opium is borrowed from Latin, which i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monoamine Oxidase
Monoamine oxidases (MAO) () are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group. They are found bound to the outer membrane of mitochondria in most cell types of the body. The first such enzyme was discovered in 1928 by Mary Bernheim in the liver and was named tyramine oxidase. The MAOs belong to the protein family of flavin-containing amine oxidoreductases. MAOs are important in the breakdown of monoamines ingested in food, and also serve to inactivate monoamine neurotransmitters. Because of the latter, they are involved in a number of psychiatric and neurological diseases, some of which can be treated with monoamine oxidase inhibitors (MAOIs) which block the action of MAOs. Subtypes and tissue distribution In humans there are two types of MAO: MAO-A and MAO-B. * Both are found in neurons and astroglia. * Outside the central nervous system: ** MAO-A is also found in the liver, pulmonary vascular end ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Enzyme
An enzyme () is a protein that acts as a biological catalyst by accelerating chemical reactions. The molecules upon which enzymes may act are called substrate (chemistry), substrates, and the enzyme converts the substrates into different molecules known as product (chemistry), products. Almost all metabolism, metabolic processes in the cell (biology), cell need enzyme catalysis in order to occur at rates fast enough to sustain life. Metabolic pathways depend upon enzymes to catalyze individual steps. The study of enzymes is called ''enzymology'' and the field of pseudoenzyme, pseudoenzyme analysis recognizes that during evolution, some enzymes have lost the ability to carry out biological catalysis, which is often reflected in their amino acid sequences and unusual 'pseudocatalytic' properties. Enzymes are known to catalyze more than 5,000 biochemical reaction types. Other biocatalysts include Ribozyme, catalytic RNA molecules, also called ribozymes. They are sometimes descr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Receptor Antagonist
A receptor antagonist is a type of receptor ligand or drug that blocks or dampens a biological response by binding to and blocking a receptor rather than activating it like an agonist. Antagonist drugs interfere in the natural operation of receptor proteins.Pharmacology Guide: In vitro pharmacology: concentration-response curves ." '' GlaxoWellcome.'' Retrieved on December 6, 2007. They are sometimes called blockers; examples include alpha blockers, beta b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Agonists
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the agonist, while an inverse agonist causes an action opposite to that of the agonist. Etymology The word originates from the Greek word (''agōnistēs''), "contestant; champion; rival" < (''agōn''), "contest, combat; exertion, struggle" < (''agō''), "I lead, lead towards, conduct; drive." Types of agonists Receptors can be activated by either endogenous agonists (such as |
Endogenous
Endogeny, in biology, refers to the property of originating or developing from within an organism, tissue, or cell. For example, ''endogenous substances'', and ''endogenous processes'' are those that originate within a living system (e.g. an organism or a cell). For instance, estradiol is an endogenous estrogen hormone A hormone (from the Ancient Greek, Greek participle , "setting in motion") is a class of cell signaling, signaling molecules in multicellular organisms that are sent to distant organs or tissues by complex biological processes to regulate physio ... produced within the body, whereas ethinylestradiol is an exogenous synthetic estrogen, commonly used in birth control pills. In contrast, '' exogenous substances'' and ''exogenous'' ''processes'' are those that originate from outside of an organism. References External links *{{Wiktionary-inline, endogeny Biology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient Greek Religion
Religious practices in ancient Greece encompassed a collection of beliefs, rituals, and Greek mythology, mythology, in the form of both popular public religion and Cult (religious practice), cult practices. The application of the modern concept of "religion" to ancient cultures has been questioned as anachronistic. The Ancient Greece, ancient Greeks did not have a word for 'religion' in the modern sense. Likewise, no Greek writer is known to have classified either the gods or the cult practices into separate 'religions'. Instead, for example, Herodotus speaks of the Hellenes as having "common shrines of the gods and sacrifices, and the same kinds of customs". Most ancient Greeks recognized the Twelve Olympians, twelve major Olympian gods and goddesses—Zeus, Hera, Poseidon, Demeter, Athena, Ares, Aphrodite, Apollo, Artemis, Hephaestus, Hermes, and either Hestia or Dionysus—although philosophies such as Stoicism and some forms of Platonism used language that seems to assume a s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scapegoat
In the Bible, a scapegoat is one of a pair of kid goats that is released into the wilderness, taking with it all sins and impurities, while the other is sacrificed. The concept first appears in the Book of Leviticus, in which a goat is designated to be cast into the desert to carry away the sins of the community. Practices with some similarities to the scapegoat ritual also appear in Ancient Greece and Ebla. Origins Some scholars have argued that the scapegoat ritual can be traced back to Ebla around 2400 BC, whence it spread throughout the ancient Near East. Etymology The word "scapegoat" is an English translation of the Hebrew (), which occurs in Leviticus 16:8: The Brown–Driver–Briggs Hebrew Lexicon gives () as a reduplicative intensive of the stem , "remove", hence , "for entire removal". This reading is supported by the Septuagint, Greek Old Testament translation as "the sender away (of sins)". The lexicographer Wilhelm Gesenius, Gesenius takes to mean "averter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmakos
A pharmakós (, plural ''pharmakoi'') in Ancient Greek religion was the ritualistic sacrifice or exile of a human scapegoat or victim. Ritual A slave, a cripple, or a criminal was chosen and expelled from the community at times of disaster (famine, invasion or plague) or at times of calendrical crisis. It was believed that this would bring about purification. On the first day of the Thargelia, a festival of Apollo at Athens, two men, the ''pharmakoi'', were led out as if to be sacrificed as an expiation. Some scholia state that ''pharmakoi'' were actually sacrificed (thrown from a cliff or burned), but many modern scholars reject this, arguing that the earliest source for the ''pharmakos'' (the iambic satirist Hipponax) shows the ''pharmakoi'' being beaten and stoned, but not executed. A more plausible explanation would be that sometimes they were executed and sometimes not, depending on the attitude of the victim. For instance, a deliberate unrepentant murderer would most likely ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
