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Periostitis
Periostitis, also known as periostalgia, is a medical condition caused by inflammation of the periosteum, a layer of connective tissue that surrounds bone. The condition is generally chronic and is marked by tenderness and swelling of the bone and pain. Causes Acute periostitis is due to infection, characterized by diffuse formation of pus, severe pain, and constitutional symptoms, and usually results in necrosis. It can be caused by excessive physical activity as well, as in the case of medial tibial stress syndrome (also referred to as tibial periostalgia, soleus periostalgia, or shin splints). Congenital infection with syphilis can also cause periostitis in newborn infants. Hypertrophic osteoarthropathy Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component Cell (biology), cells. It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number. Al ... can also cause periostit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medial Tibial Stress Syndrome
A shin splint, also known as medial tibial stress syndrome, is pain along the inside edge of the shinbone (tibia) due to inflammation of tissue in the area. Generally this is between the middle of the lower leg and the ankle. The pain may be dull or sharp, and is generally brought on by high-impact exercise that overloads the tibia. It generally resolves during periods of rest. Complications may include stress fractures. Shin splints typically occur due to excessive physical activity. Groups that are commonly affected include runners, dancers, gymnasts, and military personnel. The underlying mechanism is not entirely clear. Diagnosis is generally based on the symptoms, with medical imaging done to rule out other possible causes. Shin splints are generally treated by rest followed by a gradual return to exercise over a period of weeks. Other measures such as nonsteroidal anti-inflammatory drugs (NSAIDs), cold packs, physical therapy, and compression may be used. Shoe insoles ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periosteal Reaction
A periosteal reaction is the formation of new bone in response to injury or other stimuli of the periosteum surrounding the bone. It is most often identified on X-ray films of the bones. Cause A periosteal reaction can result from a large number of causes, including injury and chronic irritation due to a medical condition such as hypertrophic osteopathy, bone healing in response to fracture, chronic stress injuries, subperiosteal hematomas, osteomyelitis, and cancer of the bone. It may also occur as part of thyroid acropachy, a severe sign of the autoimmune thyroid disorder Graves' disease. Other causes include Menkes disease and hypervitaminosis A. It can take about three weeks to appear. Diagnosis The morphological appearance can be helpful in determining the cause of a periosteal reaction (for example, if other features of periostitis are present), but is usually not enough to be definitive. Diagnosis can be helped by establishing if bone formation is localized to a sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inflammation
Inflammation (from ) is part of the biological response of body tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin ''calor'', ''dolor'', ''rubor'', ''tumor'', and ''functio laesa''). Inflammation is a generic response, and therefore is considered a mechanism of innate immunity, whereas adaptive immunity is specific to each pathogen. Inflammation is a protective response involving immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out damaged cells and tissues, and initiate tissue repair. Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. However inflammation can also have negative effects. Too much inflammation, in the form of chronic inflammation, is associated with variou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Periosteum
The periosteum is a membrane that covers the outer surface of all bones, except at the articular surfaces (i.e. the parts within a joint space) of long bones. (At the joints of long bones the bone's outer surface is lined with "articular cartilage", a type of hyaline cartilage.) Endosteum lines the inner surface of the medullary cavity of all long bones. Structure The periosteum consists of an outer fibrous layer, and an inner ''cambium layer'' (or osteogenic layer). The fibrous layer is of dense irregular connective tissue, containing fibroblasts, while the cambium layer is highly cellular containing progenitor cells that develop into osteoblasts. These osteoblasts are responsible for increasing the width of a long bone (the length of a long bone is controlled by the epiphyseal plate) and the overall size of the other bone types. After a bone fracture A bone fracture (abbreviated FRX or Fx, Fx, or #) is a medical condition in which there is a partial or complete break ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connective Tissue
Connective tissue is one of the four primary types of animal tissue, a group of cells that are similar in structure, along with epithelial tissue, muscle tissue, and nervous tissue. It develops mostly from the mesenchyme, derived from the mesoderm, the middle embryonic germ layer. Connective tissue is found in between other tissues everywhere in the body, including the nervous system. The three meninges, membranes that envelop the brain and spinal cord, are composed of connective tissue. Most types of connective tissue consists of three main components: elastic and collagen fibers, ground substance, and cells. Blood and lymph are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the body water. The cells of connective tissue include fibroblasts, adipocytes, macrophages, mast cells and leukocytes. The term "connective tissue" (in German, ) was introduced in 1830 by Johannes Peter Müller. The tissue was already recognized as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Infection
An infection is the invasion of tissue (biology), tissues by pathogens, their multiplication, and the reaction of host (biology), host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable disease, is an Disease#Terminology, illness resulting from an infection. Infections can be caused by a wide range of pathogens, most prominently pathogenic bacteria, bacteria and viruses. Hosts can fight infections using their immune systems. Mammalian hosts react to infections with an Innate immune system, innate response, often involving inflammation, followed by an Adaptive immune system, adaptive response. Treatment for infections depends on the type of pathogen involved. Common medications include: * Antibiotics for bacterial infections. * Antivirals for viral infections. * Antifungals for fungal infections. * Antiprotozoals for protozoan infections. * Antihelminthics for infections caused by parasi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Necrosis
Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. The term "necrosis" came about in the mid-19th century and is commonly attributed to German pathologist Rudolf Virchow, who is often regarded as one of the founders of modern pathology. Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated digestion of cell components. In contrast, ''apoptosis'' is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides beneficial effects to the organism, necrosis is almost always detrimental and can be fatal. Cellular death due to necrosis does not follow the apoptotic signal transduction pathway, but rather various receptors are activated and result in the loss of cell membrane integrity and an uncontrolled release of products of cell death into the extracellular space. This initiates an inflammatory response in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypertrophic Osteoarthropathy
Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component Cell (biology), cells. It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number. Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormone, hormonally induced proliferation and enlargement of the cells of the uterus during pregnancy. Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle of heart. Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel). Gallery Gould Pyle 234.jpg, Breast hypertrophy, Breasts Hypertrophied clitoris.jpg, Clitoromegaly, Clitoris Head o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paleopathology
Paleopathology, also spelled palaeopathology, is the study of ancient diseases and injuries in organisms through the examination of fossils, mummified tissue, skeletal remains, and analysis of coprolites. Specific sources in the study of ancient human diseases may include early documents, illustrations from early books, painting and sculpture from the past. All these objects provide information on the evolution of diseases as well as how past civilizations treated conditions. Studies have historically focused on humans, although there is no evidence that humans are more prone to pathologies than any other animal. The word paleopathology is derived from the Ancient Greek roots of ''palaios'' meaning "old", ''pathos'' () meaning "experience" or "suffering", and ''-logia'' (), "study". Paleopathology is an interdisciplinary science, meaning it involves knowledge from many sectors including (but not limited to) "clinical pathology, human osteology, epidemiology, social anthropology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Borealosuchus Formidabilis
''Borealosuchus'' (meaning "northern crocodile") is an extinct genus of crocodyliforms that lived from the Late Cretaceous to the Eocene in North America. It was named by Christopher Brochu in 1997 for several species that had been assigned to ''Leidyosuchus''. The species assigned to it are: ''B. sternbergii'', the type species, from the Maastrichtian (Late Cretaceous) of Colorado, Montana, North Dakota, South Dakota, and Wyoming; ''B. acutidentatus'', from the Paleocene of Saskatchewan; ''B. formidabilis'', from the Paleocene of North Dakota; ''B. griffithi'', from the Paleocene of Alberta; and ''B. wilsoni'', from the Eocene of Wyoming. ''B. formidabilis'' is particularly well-known, represented by the remains of many individuals from the Wannagan Creek site in North Dakota. An indeterminate species is known from the Late Cretaceous Demopolis Chalk in Alabama. ''Borealosuchus'' was a mid-sized crocodyliform, with ''B. wilsoni'' measuring approximately long. Taxonomy Six spe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leidyosuchus
''Leidyosuchus'' (meaning " Leidy's crocodile") is an extinct genus of eusuchian, either an alligatoroid crocodilian or a stem-group crocodilian, from the Late Cretaceous of Alberta. It was named in 1907 by Lawrence Lambe, and the type species is ''L. canadensis''. It is known from a number of specimens from the middle Campanian age Dinosaur Park Formation. It was a medium-sized alligatoroid, with a maximum skull length greater than 40 centimeters (16 in). A number of species had been assigned to this genus over the years, including: ''L. acutidentatus'' ( Sternberg, 1932), from the Paleocene of Saskatchewan; ''L. formidabilis'' ( Erickson, 1976), from the Paleocene of North Dakota and Wyoming; ''L. gilmorei'' (Mook, 1942), from the Campanian of Alberta; ''L. multidentatus'' (Mook, 1930); ''L. riggsi'' (Schmidt, 1938); ''L. sternbergii'' ( Gilmore, 1910), from the Maastrichtian (Late Cretaceous) of Colorado, Montana, North Dakota, South Dakota, and Wyoming; and ''L. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sauropod
Sauropoda (), whose members are known as sauropods (; from '' sauro-'' + '' -pod'', 'lizard-footed'), is a clade of saurischian ('lizard-hipped') dinosaurs. Sauropods had very long necks, long tails, small heads (relative to the rest of their body), and four thick, pillar-like legs. They are notable for the enormous sizes attained by some species, and the group includes the largest animals to have ever lived on land. Well-known genera include '' Apatosaurus'', '' Argentinosaurus'', '' Alamosaurus'', ''Brachiosaurus'', '' Camarasaurus'', '' Diplodocus,'' and '' Mamenchisaurus''. The oldest known unequivocal sauropod dinosaurs are known from the Early Jurassic. '' Isanosaurus'' and '' Antetonitrus'' were originally described as Triassic sauropods, but their age, and in the case of ''Antetonitrus'' also its sauropod status, were subsequently questioned. Sauropod-like sauropodomorph tracks from the Fleming Fjord Formation (Greenland) might, however, indicate the occurrence of the g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
