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Paraldehyde Metaldehyde Synthesis
Paraldehyde is the cyclic trimer of acetaldehyde molecules. Formally, it is a derivative of 1,3,5-trioxane, with a methyl group substituted for a hydrogen atom at each carbon. The corresponding tetramer is metaldehyde. A colourless liquid, it is sparingly soluble in water and highly soluble in ethanol. Paraldehyde slowly oxidizes in air, turning brown and producing an odour of acetic acid. It quickly reacts with most plastics and rubber. Paraldehyde was first observed in 1835 by the German chemist Justus Liebig; its empirical formula was determined in 1838 by Liebig's student Hermann Fehling. The German chemist Valentin Hermann Weidenbusch (1821–1893), another of Liebig's students, synthesized paraldehyde in 1848 by treating acetaldehyde with acid (either sulfuric or nitric acid) and cooling to 0°C. He found it quite remarkable that when paraldehyde was ''heated'' with a trace of the same acid, the reaction went the other way, recreating acetaldehyde. Paraldehyde has uses in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trimer (chemistry)
In chemistry, a trimer (; ) is a molecule or polyatomic anion formed by combination or association of three molecules or ions of the same substance. In technical jargon, a trimer is a kind of oligomer derived from three identical precursors often in competition with polymerization. Examples Alkyne trimerisation In 1866, Marcellin Berthelot reported the first example of cyclotrimerization, the conversion of acetylene to benzene. This process was commercialized: : Nitrile trimerization Symmetrical 1,3,5-triazines are prepared by trimerization of certain nitriles such as cyanogen chloride or cyanimide. Cyanogen chloride and cyanogen bromide each trimerize at elevated temperatures over a carbon catalyst. The chloride gives cyanuric chloride: : The bromide has an extended shelflife when refrigerated. Like the chloride, it undergoes ab exothermic trimerisation to form cyanuric bromide. This reaction is catalyzed by traces of bromine, metal salts, acids and bases. For ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vincenzo Cervello
Vincenzo is an Italian male given name, derived from the Latin name Vincentius (the verb ''vincere'' means to win or to conquer). Notable people with the name include: Art *Vincenzo Amato (born 1966), Italian actor and sculptor *Vincenzo Bellavere (c.1540-1541 – 1587), Italian composer *Vincenzo Bellini (1801–1835), Italian composer *Vincenzo Camuccini (1771–1844), Italian academic painter *Vincenzo Catena (c. 1470 – 1531), Italian painter *Vincenzo Cerami (1940–2013), Italian screenwriter *Vincenzo Consolo (1933–2012), Italian writer *Vincenzo Coronelli (1650–1718), Franciscan friar, cosmographer, cartographer, publisher, and encyclopedist *Vincenzo Crocitti (1949–2010), Italian cinema and television actor *Vincenzo Dimech (1768–1831), Maltese sculptor *Vincenzo Galilei (1520–1591), composer, lutenist, and music theorist, father of Galileo *Vincenzo Marra (born 1972), Italian filmmaker *Vincenzo Migliaro (1858–1938), Italian painter *Vincenzo Natali (bo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Convulsion
A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is sometimes used as a synonym for ''seizure''. However, not all epileptic seizures lead to convulsions, and not all convulsions are caused by epileptic seizures. Convulsions are also consistent with an electric shock and improper enriched air scuba diving. Non-epileptic convulsions have no relation with epilepsy, and are caused by non-epileptic seizures. Convulsion is a common term generally describing uncontrollable muscle contractions. The term convulsion has been used interchangeably with the word "seizure". Seizures may cause a person to have convulsions, but this is not always the case. Convulsion is a type of seizure that involves bursts of electrical activity in the brain. Occasionally the reason for a convulsion is unfamiliar. A convulsion may be caus ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Geriatrics
Geriatrics, or geriatric medicine, is a medical specialty focused on providing care for the unique health needs of older adults. The term ''geriatrics'' originates from the Greek γέρων ''geron'' meaning "old man", and ιατρός ''iatros'' meaning "healer". It aims to promote health by preventing, diagnosing and treating disease in older adults. There is no defined age at which patients may be under the care of a geriatrician, or geriatric physician, a physician who specializes in the care of elderly people. Rather, this decision is guided by individual patient need and the caregiving structures available to them. This care may benefit those who are managing multiple chronic conditions or experiencing significant age-related complications that threaten quality of daily life. Geriatric care may be indicated if caregiving responsibilities become increasingly stressful or medically complex for family and caregivers to manage independently. There is a distinction between ger ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychiatric Hospital
Psychiatric hospitals, also known as mental health hospitals, behavioral health hospitals, are hospitals or wards specializing in the treatment of severe mental disorders, such as schizophrenia, bipolar disorder, eating disorders, dissociative identity disorder, major depressive disorder and many others. Psychiatric hospitals vary widely in their size and grading. Some hospitals may specialize only in short-term or outpatient therapy for low-risk patients. Others may specialize in the temporary or permanent containment of patients who need routine assistance, treatment, or a specialized and controlled environment due to a psychiatric disorder. Patients often choose voluntary commitment, but those whom psychiatrists believe to pose significant danger to themselves or others may be subject to involuntary commitment and involuntary treatment. Psychiatric hospitals may also be called psychiatric wards/units (or "psych" wards/units) when they are a subunit of a regular hospit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Delirium Tremens
Delirium tremens (DTs) is a rapid onset of confusion usually caused by withdrawal from alcohol. When it occurs, it is often three days into the withdrawal symptoms and lasts for two to three days. Physical effects may include shaking, shivering, irregular heart rate, and sweating. People may also hallucinate. Occasionally, a very high body temperature or seizures (colloquially known as "rum fits") may result in death. Alcohol is one of the most dangerous drugs to withdraw from. Delirium tremens typically only occurs in people with a high intake of alcohol for more than a month. A similar syndrome may occur with benzodiazepine and barbiturate withdrawal. Withdrawal from stimulants such as cocaine do not have major medical complications. In a person with delirium tremens it is important to rule out other associated problems such as electrolyte abnormalities, pancreatitis, and alcoholic hepatitis. Prevention is by treating withdrawal symptoms. If delirium tremens occur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Bodkin Adams
John Bodkin Adams (21 January 18994 July 1983) was an Irish-born British general practitioner, convicted fraudster, and suspected serial killer. Between 1946 and 1956, 163 of his patients died while in comas, which was deemed to be worthy of investigation. In addition, 132 out of 310 patients had left Adams money or items in their wills. Adams was tried and acquitted for the murder of one patient in 1957, while another count of murder was withdrawn by the prosecution in what was later described as "an abuse of process" by the presiding judge Patrick Devlin, Baron Devlin, causing questions to be asked in Parliament of the United Kingdom about the prosecution's handling of events. Adams was found guilty in a subsequent trial of thirteen offences of prescription drug fraud, lying on cremation forms, obstruction of justice during a police search, and failing to keep a dangerous drugs register. He was struck off by the General Medical Council in 1957 and reinstated in 1961 after t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edith Alice Morrell
Edith Alice Morrell (20 June 1869 – 13 November 1950) was a resident of Eastbourne, East Sussex, England, and patient of Dr John Bodkin Adams. Although Adams was acquitted in 1957 of her murder, the question of Adams' role in Morrell's death excited considerable interest at the time and continues to do so. This is partly because of negative pre-trial publicity which remains in the public record, partly because of the several dramatic incidents in the trial and partly as Adams declined to give evidence in his own defence. The trial featured in headlines around the worldNot Guilty '''', 22 April 1957. and was described at the time as "one of t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placebo Effect
A placebo ( ) is a substance or treatment which is designed to have no therapeutic value. Common placebos include inert tablets (like sugar pills), inert injections (like saline), sham surgery, and other procedures. In general, placebos can affect how patients perceive their condition and encourage the body's chemical processes for relieving pain and a few other symptoms, but have no impact on the disease itself. Improvements that patients experience after being treated with a placebo can also be due to unrelated factors, such as regression to the mean (a statistical effect where an unusually high or low measurement is likely to be followed by a less extreme one). The use of placebos in clinical medicine raises ethical concerns, especially if they are disguised as an active treatment, as this introduces dishonesty into the doctor–patient relationship and bypasses informed consent. While it was once assumed that this deception was necessary for placebos to have any effect, ther ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cough Medicine
Cold medicines are a group of medications taken individually or in combination as a treatment for the symptoms of the common cold and similar conditions of the upper respiratory tract. The term encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. It also includes drugs which are marketed as cough suppressants or antitussives, but their effectiveness in reducing cough symptoms is unclear or minimal. While they have been used by 10% of American children in any given week, they are not recommended in Canada or the United States in children six years or younger because of lack of evidence showing effect and concerns of harm. In 2020, one version containing codeine and guaifenesin was the 377th most commonly prescribed medication in the United States with more than 400thousand prescriptions. Types There are a number of different cough and cold medications, which may be used for various coughing symptoms. The commercial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sedative
A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but the majority of them affect the neurotransmitter gamma-aminobutyric acid (GABA). In spite of the fact that each sedative acts in its own way, most produce relaxing effects by increasing GABA activity. This group is related to hypnotics. The term ''sedative'' describes drugs that serve to calm or relieve anxiety, whereas the term ''hypnotic'' describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness) they are often referred to collectively as ''sedative-hypnotic'' drugs. Sedatives can be used to produce an overly-calming effect ( alcohol being th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hypnotic
Hypnotic (from Greek ''Hypnos'', sleep), or soporific drugs, commonly known as sleeping pills, are a class of (and umbrella term for) psychoactive drugs whose primary function is to induce sleep (or surgical anesthesiaWhen used in anesthesia to produce and maintain unconsciousness, "sleep" is metaphorical as there are no regular sleep stages or cyclical natural states; patients rarely recover from anesthesia feeling refreshed and with renewed energy. The word is also used in art.) and to treat insomnia (sleeplessness). This group of drugs is related to sedatives''. ''Whereas the term sedative describes drugs that serve to calm or relieve anxiety, the term hypnotic generally describes drugs whose main purpose is to initiate, sustain, or lengthen sleep. Because these two functions frequently overlap, and because drugs in this class generally produce dose-dependent effects (ranging from anxiolysis to loss of consciousness), they are often referred to collectively as sedative- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
