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Papillary Thyroid Cancer
Papillary thyroid cancer (papillary thyroid carcinoma, PTC) is the most common type of thyroid cancer, representing 75 percent to 85 percent of all thyroid cancer cases.Chapter 20 in: 8th edition. It occurs more frequently in women and presents in the 20–55 year age group. It is also the predominant cancer type in children with thyroid cancer, and in patients with thyroid cancer who have had previous radiation to the head and neck. It is often well- differentiated, slow-growing, and localized, although it can metastasize. Diagnosis Papillary thyroid carcinoma is usually discovered on routine examination as an asymptomatic thyroid nodule that appears as a neck mass. In some instances, the mass may have produced local symptoms. This mass is normally referred to a fine needle aspiration biopsy (FNA) for investigation. FNA accuracy is very high and it is a process widely used in these cases. Other investigation methods include ultrasound imaging and nuclear scan. The ultrasound is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pap Stain
Papanicolaou stain (also Papanicolaou's stain and Pap stain) is a multichromatic (multicolored) cytological staining technique developed by George Papanicolaou in 1942. The Papanicolaou stain is one of the most widely used stains in cytology, where it is used to aid pathologists in making a diagnosis. Although most notable for its use in the detection of cervical cancer in the Pap test or Pap smear, it is also used to stain non- gynecological specimen preparations from a variety of bodily secretions and from small needle biopsies of organs and tissues. Papanicolaou published three formulations of this stain in 1942, 1954, and 1960. Usage Pap staining is used to differentiate cells in smear preparations (in which samples are spread or smeared onto a glass microscope slide) from various bodily secretions and needle biopsies; the specimens may include gynecological smears ( Pap smears), sputum, brushings, washings, urine, cerebrospinal fluid, abdominal fluid, pleural fluid, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papillary Carcinoma Of The Thyroid
Papilla (Latin, 'nipple') or papillae may refer to: In animals * Papilla (fish anatomy), in the mouth of fish * Papilla (worms), small bumps on the surface of certain worms * Basilar papilla, a sensory organ of lizards, amphibians and fish * Dental papilla, in a developing tooth * Dermal papillae, part of the skin structure * Major duodenal papilla, in the duodenum * Minor duodenal papilla, in the duodenum * Genital papilla, a feature of the external genitalia of some animals * Mammary papilla or nipple, a raised region of tissue on the surface of the breast * Interdental papilla, part of the gums * Lacrimal papilla, on the bottom eyelid * Lingual papillae, small structures on the upper surface of the tongue * Renal papilla, part of the kidney * Tumor papilla, consisting of tumor cells surrounding a fibrovascular core In plants and fungi * Papilla (mycology), a nipple-shaped protrusion in the center of the cap * Stigmatic papilla, part of the stigma (botany) See also * * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitochondria
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'', meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 ''Scientific American'' article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). The multicellular animal '' Henneguya salminicola'' is known to have retained mitochondrion-related organelles despite a complete loss of their mitochondrial genome. A large number of unicellular organisms, such as microspo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Snowflake
A snowflake is a single ice crystal that is large enough to fall through the Earth's atmosphere as snow.Knight, C.; Knight, N. (1973). Snow crystals. Scientific American, vol. 228, no. 1, pp. 100–107.Hobbs, P.V. 1974. Ice Physics. Oxford: Clarendon Press. Snow appears white in color despite being made of clear ice. This is because the many small crystal facets of the snowflakes scatter the sunlight between them. Each flake begins by forming around a tiny particle, called its nucleus, accumulating water droplets, which freeze and slowly form a crystal. Complex shapes emerge as the flake moves through differing temperature and humidity zones in the atmosphere, and possibly combines with other snowflakes. Because of this, snowflakes tend to look very different from one another. However, they may be categorized in eight broad classifications and at least 80 individual variants. The main constituent shapes for ice crystals, from which combinations may occur, are ''needle'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lungs
The lungs are the primary organs of the respiratory system in many animals, including humans. In mammals and most other tetrapods, two lungs are located near the backbone on either side of the heart. Their function in the respiratory system is to extract oxygen from the atmosphere and transfer it into the bloodstream, and to release carbon dioxide from the bloodstream into the atmosphere, in a process of gas exchange. Respiration is driven by different muscular systems in different species. Mammals, reptiles and birds use their musculoskeletal systems to support and foster breathing. In early tetrapods, air was driven into the lungs by the pharyngeal muscles via buccal pumping, a mechanism still seen in amphibians. In humans, the primary muscle that drives breathing is the diaphragm. The lungs also provide airflow that makes vocalisation including speech possible. Humans have two lungs, a right lung and a left lung. They are situated within the thoracic cavity of the c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Vessels
Blood vessels are the tubular structures of a circulatory system that transport blood throughout many animals’ bodies. Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body. They also take waste and carbon dioxide away from the tissues. Some tissues such as cartilage, epithelium, and the lens and cornea of the eye are not supplied with blood vessels and are termed ''avascular''. There are five types of blood vessels: the arteries, which carry the blood away from the heart; the arterioles; the capillaries, where the exchange of water and chemicals between the blood and the tissues occurs; the venules; and the veins, which carry blood from the capillaries back towards the heart. The word ''vascular'', is derived from the Latin ''vas'', meaning ''vessel'', and is mostly used in relation to blood vessels. Etymology * artery – late Middle English; from Latin ''arteria'', from Greek ''artēria'', probably from ''airein'' ("raise ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lymphatics
The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels (tubes), structured like blood vessels, that carry lymph. As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vessels are lined by endothelial cells, and have a thin layer of smooth muscle, and adventitia that binds the lymph vessels to the surrounding tissue. Lymph vessels are devoted to the propulsion of the lymph from the lymph capillaries, which are mainly concerned with the absorption of interstitial fluid from the tissues. Lymph capillaries are slightly bigger than their counterpart capillaries of the vascular system. Lymph vessels that carry lymph to a lymph node are called afferent lymph vessels, and those that carry it from a lymph node are called efferent lymph vessels, from where the lymph may travel to another lymph node, may be returned to a vein, or may travel to a larger lymph duct. Lymph ducts drain the lymph into one of the subclavian ve ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noninvasive Follicular Thyroid Neoplasm With Papillary-like Nuclear Features
Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is an indolent thyroid tumor that was previously classified as an encapsulated follicular variant of papillary thyroid carcinoma, necessitating a new classification as it was recognized that encapsulated tumors without invasion have an indolent behavior, and may be over-treated if classified as a type of cancer. Signs and symptoms The clinical presentation of the patients is identical to other thyroid tumors, where there is usually a painless, asymptomatic, mobile thyroid gland nodule or enlargement. Depending on the size, additional symptoms of hoarseness, difficulty swallowing, or other compression symptoms may be experienced. In nearly all cases, the patients do not have any thyroid hormone dysfunction (hyperthyroidism or hypothyroidism – respectively, excessive or low hormone levels). Genetics This tumor shows a very high association with other follicular-pattern tumors, with Ras gene, RAS m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Active Surveillance Of Low-risk Papillary Thyroid Microcarcinoma
Active surveillance is an observational management being increasingly accepted as an alternative over immediate surgery due to low-risk papillary thyroid microcarcinoma with no evidence of extension or metastatic spread. Patients on active surveillance are observed with periodical ultrasound examinations and thyroid function tests. If disease progression is detected, patients are treated with surgery. The chances of thyroid cancer increased during the past 3 decades in many countries, mostly due to increased detection of small papillary thyroid carcinoma, without associated increase in mortality from thyroid cancer. Therefore, researchers declared a warning of increased overdiagnosis and overtreatment for thyroid cancerAkira Miyauchiproposed active surveillance management in 1993, when he was an associate professor of Department of Surgery, Kagawa Medical University (now Kagawa University Faculty of Medicine) and a registered doctor at Kuma Hospital (Kobe, Hyogo Prefecture, Jap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hematogenous
Bloodstream infections (BSIs) are infections of blood caused by blood-borne pathogens. The detection of microbes in the blood (most commonly accomplished by blood cultures) is always abnormal. A bloodstream infection is different from sepsis, which is characterized by severe inflammatory or immune responses of the host organism to pathogens. Bacteria can enter the bloodstream as a severe complication of infections (like pneumonia or meningitis), during surgery (especially when involving mucous membranes such as the gastrointestinal tract), or due to catheters and other foreign bodies entering the arteries or veins (including during intravenous drug abuse). Transient bacteremia can result after dental procedures or brushing of teeth. Bacteremia can have several important health consequences. Immune responses to the bacteria can cause sepsis and septic shock, which, particularly if severe sepsis and then septic shock occurs, have high mortality rates, especially if not treated q ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psammoma
A psammoma body is a round collection of calcium, seen microscopically. The term is derived . Cause Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from, # Infarction and calcification of papillae tips. # Calcification of intralymphatic tumor thrombi. Association with lesions Psammoma bodies are commonly seen in certain tumors such as: * Papillary thyroid carcinoma * Papillary renal cell carcinoma * Ovarian papillary serous cystadenoma and cystadenocarcinoma * Endometrial adenocarcinomas (papillary serous carcinoma ~3%-4%) * Meningiomas, in the central nervous system * Peritoneal and pleural mesothelioma * Somatostatinoma (pancreas) * Prolactinoma of the pituitary *Glucagonoma * Micropapillary subtype of lung adenocarcinoma Benign lesions Psammoma bodies may be seen in: * Endosalpingiosis * Psammomatous melanotic schwannoma * Melanocytic nevusRapini, Ronald. ''Practical Dermatopathology''. Elsevier Mosby, 2005, p. 1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Staining
Staining is a technique used to enhance contrast in samples, generally at the Microscope, microscopic level. Stains and dyes are frequently used in histology (microscopic study of biological tissue (biology), tissues), in cytology (microscopic study of cell (biology), cells), and in the medical fields of histopathology, hematology, and cytopathology that focus on the study and diagnoses of diseases at the microscopic level. Stains may be used to define biological tissues (highlighting, for example, muscle fibers or connective tissue), cell (biology), cell populations (classifying different blood cells), or organelles within individual cells. In biochemistry, it involves adding a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound. Staining and fluorescent tagging can serve similar purposes. Biological staining is also used to mark cells in flow cytometry, and to flag proteins or nucleic acids in gel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
