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Oxfendazole
Oxfendazole is a broad spectrum benzimidazole anthelmintic. Its main use is for protecting livestock against roundworm, strongyles and pinworms. Oxfendazole is the sulfoxide metabolite of fenbendazole. Oxfendazole is an anthelmintic (wormer) compound used in veterinary practice. It comes under the chemical class of the benzimidazoles. This drug is barely used in horses, goats, sheep, and cattle. It is very scarcely applied on dogs and cats. The drug for livestock is majorly available in the form of pills, tablets, drenches, bolus, etc. They are meant for oral consumption. Several drenches are allowed for intraruminal injection in some of the countries. Few countries also prefer injectables and pour-ons. For pet dogs, the drug is available in the form of drenches. Efficacy Both oxfendazole and fenbendazole are efficacious against gastrointestinal lungworms and roundworms of livestock, adults, and L4-larvae of the significant species for example, of the genera ''Bunostomum'', '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fenbendazole
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus '' Taenia'' (but not effective against ''Dipylidium caninum'', a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals. Drug interactions Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions in cattle and death in sheep have been reported after using these medications together. Abortions in domestic ruminants have been associated with concurrent use of anti-trematode therapeutic agents. Toxicity Fenbendazole is poorly absorbed from the gastrointestinal tract in most species. The in laboratory animals exceeds 10 g/kg when administered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benzimidazole
Benzimidazole is a heterocyclic aromatic organic compound. This bicyclic compound may be viewed as fused rings of the aromatic compounds benzene and imidazole. It is a colorless solid. Preparation Benzimidazole is produced by condensation of o-phenylenediamine with formic acid,. or the equivalent trimethyl orthoformate: :C6H4(NH2)2 + HC(OCH3)3 → C6H4N(NH)CH + 3 CH3OH 2-substituted derivatives are obtained when the condensation is conducted with aldehydes in place of formic acid, followed by oxidation.Robert A. Smiley "Phenylene- and Toluenediamines" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. Reactions Benzimidazole is a base: :C6H4N(NH)CH + H+ → [C6H4(NH)2CH]+ It can also be deprotonated with stronger bases: :C6H4N(NH)CH + LiH → Li [C6H4N2CH] + H2 The imine can be alkylated and also serves as a ligand in coordination chemistry. The most prominent benzimidazole complex features ''N''-ribosyl-dimethylbenzimidazole as found ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oesophagostomum
''Oesophagostomum'' is a genus of parasitic nematodes (roundworms) of the family Strongylidae. These worms occur in Africa, Brazil, China, Indonesia and the Philippines. The majority of human infection with ''Oesophagostomum'' is localized to northern Togo and Ghana. Because the eggs may be indistinguishable from those of the hookworms (which are widely distributed and can also rarely cause helminthomas), the species causing human helminthomas are rarely identified with accuracy. ''Oesophagostomum'', especially ''O. bifurcum'', are common parasites of livestock and animals like goats, pigs and non-human primates, although it seems that humans are increasingly becoming favorable hosts as well. The disease they cause, oesophagostomiasis, is known for the nodule formation it causes in the intestines of its infected hosts, which can lead to more serious problems such as dysentery. Although the routes of human infection have yet to be elucidated sufficiently, it is believed that transm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sulfoxides
In organic chemistry, a sulfoxide, also called a sulphoxide, is an organosulfur compound containing a sulfinyl () functional group attached to two carbon atoms. It is a polar functional group. Sulfoxides are oxidized derivatives of sulfides. Examples of important sulfoxides are alliin, a precursor to the compound that gives freshly crushed garlic its aroma, and dimethyl sulfoxide (DMSO), a common solvent. Structure and bonding Sulfoxides feature relatively short S–O distances. In DMSO, the S–O distance is 1.531 Å. The sulfur center is pyramidal; the sum of the angles at sulfur is about 306°.. Sulfoxides are generally represented with the structural formula R−S(=O)−R', where R and R' are organic groups. The bond between the sulfur and oxygen atoms is intermediate of a dative bond and a polarized double bond. The double-bond resonance form implies 10 electrons around sulfur (10-S-3 in N-X-L notation). The double-bond character of the S−O bond may be accounted ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthelmintics
Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may also be called vermifuges (those that stun) or vermicides (those that kill). Anthelmintics are used to treat people who are infected by helminths, a condition called helminthiasis. These drugs are also used to treat infected animals. Pills containing anthelmintics are used in mass deworming campaigns of school-aged children in many developing countries. The drugs of choice for soil-transmitted helminths are mebendazole and albendazole; for schistosomiasis and tapeworms it is praziquantel. Types Antiparasitics that specifically target worms of the genus ''Ascaris'' are called ascaricides. * Benzimidazoles: ** Albendazole – effective against threadworms, roundworms, whipworms, tapeworms, hookworms ** Mebendazole – effective against va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trichuris
''Trichuris'', often referred to as whipworms (which typically refers to ''T. trichiura'' only in medicine, and to any other species in veterinary medicine), is a genus of parasitic worms from the roundworm family Trichuridae, which are helminths. The name whipworm refers to the shape of the worm; they look like whips with wider "handles" at the posterior end. The name ''Trichocephalus'' is sometimes used for this genus. Species The genus ''Trichuris'' includes over 20 species, which infect the large intestine of their host, including: * ''Trichuris trichiura'' (sometimes ''Trichocephalus trichiurus'') – causes trichuriasis in humans * ''Trichuris campanula'' (cat whipworm) * '' Trichuris serrata'' (cat whipworm) * ''Trichuris suis'' (pig whipworm) * ''Trichuris muris'' (mouse whipworm) * ''Trichuris vulpis'' (dog whipworm) A new species – as yet unnamed – has been identified in François’ leaf monkey ('' Trachypithecus francoisi''). Other species in this genus includ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dictyocaulus
''Dictyocaulus'' is a genus of nematode parasites of the bronchial tree of horses, sheep, goats, deer, and cattle. ''Dictyocaulus arnfieldi'' is the lungworm of horses, and ''Dictyocaulus viviparus'' is the lungworm affecting ruminants. ''Dictyocaulus viviparus'': lungworm of cattle, deer ''Dictyocaulus viviparus'' is the most common lungworm of cattle; the infection is also known as ''husk'' or '' parasitic bronchitis''. Although classified as the same parasite, some people believe that the ''D. viviparus'' of deer and elk should be reclassified as a different species, including ''D. eckertii'' in New Zealand. However, both species have been shown capable of cross-infecting cattle and cervids (at least in New Zealand) . The parasite has a simple but interesting life cycle, with dispersal facilitated by a fungus. Adult ''D. viviparus'' worms reside in the bronchial tree of the animal's lungs. They lay eggs into the airways (bronchi). These eggs are coughed up and subsequ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trichostrongylus
''Trichostrongylus'' species are nematodes (round worms), which are ubiquitous among herbivores worldwide, including cattle, sheep, donkeys, goats, deer, and rabbits.Garcia LS, editor. Diagnostic Medical Parasitology. 5 ed. Washington, DC: ASM Press; 2007.Strickland GT, editor. Hunter's Tropical Medicine and Emerging Infectious Diseases. 8 ed. Philadelphia, PA: WB Saunders Company; 2000. At least 10 ''Trichostrongylus'' species have been associated with human infections. Infections occur via ingestion of infective larvae from contaminated vegetables or water. Epidemiological studies indicate a worldwide distribution of ''Trichostrongylus'' infections in humans, with the highest prevalence rates observed in individuals from regions with poor sanitary conditions, in rural areas, or who are farmers / herders. Human infections are most prevalent in the Middle East and Asia, with a worldwide estimated prevalence of 5.5 million people. Life cycle Eggs are passed through the feces of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cooperia (nematode)
''Cooperia'' is a genus of nematode from the Cooperiidae family that is one of the most common intestinal parasitic nematodes in cattle in temperate regions. Infections with ''Cooperia'' may result in mild clinical symptoms, but can lead to weight loss and damage of the small intestine, especially when co-infections with other nematodes such as '' Ostertagia ostertagi'' occur. Infections are usually treated with broad-spectrum anthelmintics such as benzimidazole, but resistance to these drugs has developed in the last decades and is now very common. ''Cooperia'' has a direct life cycle. Infective larvae are ingested by the host. The larvae grow to adults, which reproduce in the small intestines. Eggs are shed onto the pasture with the faeces, which leads to new infections. Co-infections with other gastro-intestinal nematodes such as '' O. ostertagi'' and ''Haemonchus contortus ''Haemonchus contortus'', also known as the barber's pole worm, is a very common parasite and one of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Teladorsagia
''Teladorsagia'' is a genus of nematodes belonging to the family Trichostrongylidae Trichostrongylidae is a family of nematode in the suborder Strongylida. Genera Genera: * '' Africanastrongylus'' Hoberg, Abrams & Ezenwa, 2008 * '' Amidostomoides'' Petrova, 1987 * '' Arnfieldia'' Sarwar, 1957 * '' Ashworthius'' Le Roux, 1930 * ' .... The genus has cosmopolitan distribution. Species: *'' Teladorsagia circumcincta'' *'' Teladorsagia davtiani'' *'' Teladorsagia trifurcata'' References {{Taxonbar, from=Q10692538 Nematodes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nematodirus
Trichostrongyloidea is a superfamily of nematodes under the order Strongylida. Includes genera such as ''Ostertagia'', ''Teladorsagia'', ''Trichostrongylus'', ''Haemonchus'', '' Cooperia'', ''Nematodirus'', ''Dictyocaulus ''Dictyocaulus'' is a genus of nematode parasites of the bronchial tree of horses, sheep, goats, deer, and cattle. ''Dictyocaulus arnfieldi'' is the lungworm of horses, and ''Dictyocaulus viviparus'' is the lungworm affecting ruminants. ''Dict ...''. References Strongylida Animal superfamilies {{Rhabditida-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ostertagia
''Ostertagia'' is a genus of nematodes belonging to the family Trichostrongylidae. The genus has cosmopolitan distribution. Species: *'' Ostertagia antipini'' *''Ostertagia arctica'' *'' Ostertagia buriatica'' *''Ostertagia dahurica'' *'' Ostertagia drozdzi'' *'' Ostertagia gruehneri'' *'' Ostertagia kolchida'' *''Ostertagia lasensis'' *''Ostertagia leptospicularis'' *''Ostertagia lyrataeformis'' *''Ostertagia mossi'' *''Ostertagia murmani'' *''Ostertagia nemorhaedi'' *''Ostertagia orloffi'' *''Ostertagia ostertagi'' *''Ostertagia skrjabini'' *''Ostertagia trifurcata'' *''Ostertagia volgaensis ''Ostertagia'' is a genus of nematodes belonging to the family Trichostrongylidae. The genus has cosmopolitan distribution. Species: *''Ostertagia antipini'' *''Ostertagia arctica'' *''Ostertagia buriatica'' *''Ostertagia dahurica'' *''Oste ...'' References {{Taxonbar, from=Q5267925 Nematodes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
