National Psychosis Unit
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National Psychosis Unit
The National Psychosis Unit is a national treatment centre for patients with schizophrenia and other psychotic disorders, in the United Kingdom. The unit is a tertiary referral centre in the National Health Service. It is located at the Bethlem Royal Hospital, part of the South London and Maudsley NHS Foundation Trust. It is closely affiliated to the Institute of Psychiatry, King's College London, and forms part of the Psychosis Clinical Academic Group of King's Health Partners. History The Unit was set up in the early 1990s. It was one of the first units in the UK to offer the antipsychotic drug clozapine, following its reintroduction in the UK in 1990. Staff The service has a multidisciplinary team of doctors, nurses, pharmacists and psychologists, many of whom work part of their time as clinical scientists and researchers, investigating the causes of psychotic disorders, and the effectiveness of both existing and new treatments. * Sir Robin Murray, Professor of Psychi ...
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London Borough Of Bromley
The London Borough of Bromley () is the southeasternmost of the London boroughs that make up Greater London, bordering the ceremonial county of Kent, which most of Bromley was part of before 1965. The borough's population is an estimated 332,336. It is named after Bromley, its principal town; other major towns are Penge, Hayes, West Wickham, Chislehurst, Beckenham and Orpington. The local authority is Bromley London Borough Council. Geography The borough is the largest in Greater London by area and occupies . The majority of the borough is Metropolitan Green Belt, including nearly all of the land south of the A232-A21 route between West Wickham and Pratt's Bottom. Consequently, it is also perhaps the most rural borough and contains more of the North Downs than any other, as that escarpment is broad between Bromley and Banstead. This is also reflected in its population density, which is the lowest of the 32 London boroughs. Most of the population lives in the north and west of t ...
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Psychiatric Hospital
Psychiatric hospitals, also known as mental health hospitals, behavioral health hospitals, are hospitals or wards specializing in the treatment of severe mental disorders, such as schizophrenia, bipolar disorder, eating disorders, dissociative identity disorder, major depressive disorder and many others. Psychiatric hospitals vary widely in their size and grading. Some hospitals may specialize only in short-term or outpatient therapy for low-risk patients. Others may specialize in the temporary or permanent containment of patients who need routine assistance, treatment, or a specialized and controlled environment due to a psychiatric disorder. Patients often choose voluntary commitment, but those whom psychiatrists believe to pose significant danger to themselves or others may be subject to involuntary commitment and involuntary treatment. Psychiatric hospitals may also be called psychiatric wards/units (or "psych" wards/units) when they are a subunit of a regular hospital. ...
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Institute Of Psychiatry
The Institute of Psychiatry, Psychology and Neuroscience (IoPPN) is a research institution dedicated to discovering what causes mental illness and diseases of the brain. In addition, its aim is to help identify new treatments for them and ways to prevent them in the first place. The IoPPN is a faculty of King's College London, England, previously known as the Institute of Psychiatry (IoP). The institute works closely with South London and Maudsley NHS Foundation Trust. Many senior academic staff also work as honorary consultants for the trust in clinical services such as the National Psychosis Unit at Bethlem Royal Hospital. The impact of the institute's work was judged to be 100% 'world-leading' or 'internationally-excellent' in the Research Excellence Framework (REF 2014). The research environment of the institute was also rated 100% 'world-leading'. King's College London was rated the second for research in Psychology, Psychiatry and Neuroscience in REF 2014. According to ...
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Schizophrenia
Schizophrenia is a mental disorder characterized by continuous or relapsing episodes of psychosis. Major symptoms include hallucinations (typically hearing voices), delusions, and disorganized thinking. Other symptoms include social withdrawal, decreased emotional expression, and apathy. Symptoms typically develop gradually, begin during young adulthood, and in many cases never become resolved. There is no objective diagnostic test; diagnosis is based on observed behavior, a history that includes the person's reported experiences, and reports of others familiar with the person. To be diagnosed with schizophrenia, symptoms and functional impairment need to be present for six months (DSM-5) or one month (ICD-11). Many people with schizophrenia have other mental disorders, especially substance use disorders, depressive disorders, anxiety disorders, and obsessive–compulsive disorder. About 0.3% to 0.7% of people are diagnosed with schizophrenia during their lifetime. In 2 ...
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United Kingdom
The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It comprises England, Scotland, Wales and Northern Ireland. The United Kingdom includes the island of Great Britain, the north-eastern part of the island of Ireland, and many smaller islands within the British Isles. Northern Ireland shares a land border with the Republic of Ireland; otherwise, the United Kingdom is surrounded by the Atlantic Ocean, the North Sea, the English Channel, the Celtic Sea and the Irish Sea. The total area of the United Kingdom is , with an estimated 2020 population of more than 67 million people. The United Kingdom has evolved from a series of annexations, unions and separations of constituent countries over several hundred years. The Treaty of Union between the Kingdom of England (which included Wales, annexed in 1542) and the Kingdom of Scotland in 170 ...
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Bethlem Royal Hospital
Bethlem Royal Hospital, also known as St Mary Bethlehem, Bethlehem Hospital and Bedlam, is a psychiatric hospital in London. Its famous history has inspired several horror books, films and TV series, most notably '' Bedlam'', a 1946 film with Boris Karloff. The hospital is closely associated with King's College London and, in partnership with the Institute of Psychiatry, Psychology and Neuroscience, is a major centre for psychiatric research. It is part of the King's Health Partners academic health science centre and the National Institute for Health and Care Research (NIHR) Biomedical Research Centre for Mental Health. Founded in 1247, the hospital was originally near Bishopsgate just outside the walls of the City of London. It moved a short distance to Moorfields in 1676, and then to St George's Fields in Southwark in 1815, before moving to its current location in Monks Orchard in 1930. The word " bedlam", meaning uproar and confusion, is derived from the hospital's nickn ...
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South London And Maudsley NHS Foundation Trust
South London and Maudsley NHS Foundation Trust, also known as SLaM, is an NHS foundation trust based in London, England, which specialises in mental health. It comprises four psychiatric hospitals (Bethlem Royal Hospital, Lambeth Hospital and the Maudsley Hospital), the Ladywell Unit based at University Hospital Lewisham, and over 100 community sites and 300 clinical teams. SLaM forms part of the institutions that make up King's Health Partners, an academic health science centre. In its most recent inspection of the Trust, the CQC gave SLaM a 'good' rating overall, but a 'requires improvement' rating in area of safety. In 2019, Southwark Coroner's Court ruled that SLaM was guilty of "neglect and serious failures" in relation to the death of a patient in 2018. In 2020, a further investigation into the Trust's conduct was opened following the death of a patient in its care. Overview Each year the South London and Maudsley NHS Foundation Trust provides about 5,000 people with h ...
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King's Health Partners
King's Health Partners is an academic health science centre located in London, United Kingdom. It comprises King's College London, Guy's and St Thomas' NHS Foundation Trust, King's College Hospital NHS Foundation Trust and South London and Maudsley NHS Foundation Trust. King's Health Partners' member organisations have a combined annual turnover of around £3.7 billion, treat over 4.8 million patients each year, employ approximately 40,000 staff and teach nearly 30,000 students. It forms one of the largest centres for healthcare education in Europe. History The four partners announced their intention to form an academic health science centre in April 2008. On 9 March 2009 the UK Department of Health announced that King's Health Partners would be one of six academic health science centres established in England. Research King's Health Partners incorporates some Medical Research Council centres, including the following: * MRC-Asthma UK Centre in Allergic Mechanisms o ...
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Clozapine
Clozapine is a psychiatric medication and is the first atypical antipsychotic (also called second-generation antipsychotic). It is primarily used to treat people with schizophrenia and schizoaffective disorders who have had an inadequate response to other antipsychotics or who have been unable to tolerate other drugs due to extrapyramidal side effects. It is also used for the treatment of psychosis in Parkinson's disease. Clozapine is regarded as the gold-standard treatment when other medication has been insufficiently effective and its use is recommended by multiple international treatment guidelines, after resistance to earlier neuroleptic treatment is established. The role of clozapine in treatment-resistant schizophrenia was established by a 1988 landmark study in which clozapine showed marked benefits compared to chlorpromazine in a group of patients with protracted psychosis who had already shown an inadequate response to other antipsychotics. While there are significan ...
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Robin Murray
Sir Robin MacGregor Murray FRS (born 31 January 1944 in Glasgow) is a Scottish psychiatrist, Professor of Psychiatric Research at the Institute of Psychiatry, King's College London. He has treated patients with schizophrenia and bipolar illness referred to the National Psychosis Unit of the South London and Maudsley NHS Trust because they fail to respond to treatment, or cannot get appropriate treatment, locally; he sees patients privately if they are unable to obtain an NHS referral. Education and career Robin Murray trained in medicine at the University of Glasgow. After qualifying, he researched chronic renal failure induced by the massive abuse of a local headache powder, Askit Powders. Then he started training in psychiatry at the Maudsley Hospital in London, and has remained there ever since apart from one year at the National Institute of Mental Health in the USA. He has been Dean of the Institute of Psychiatry, King's College London, and Professor of Psychiatry t ...
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Bipolar Disorder
Bipolar disorder, previously known as manic depression, is a mental disorder characterized by periods of depression and periods of abnormally elevated mood that last from days to weeks each. If the elevated mood is severe or associated with psychosis, it is called mania; if it is less severe, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy or irritable, and they often make impulsive decisions with little regard for the consequences. There is usually also a reduced need for sleep during manic phases. During periods of depression, the individual may experience crying and have a negative outlook on life and poor eye contact with others. The risk of suicide is high; over a period of 20 years, 6% of those with bipolar disorder died by suicide, while 30–40% engaged in self-harm. Other mental health issues, such as anxiety disorders and substance use disorders, are commonly associated with bipolar disorder. While the causes of ...
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National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the "NHS" name ( NHS England, NHS Scotland and NHS Wales). Health and Social Care in Northern Ireland was created separately and is often locally referred to as "the NHS". The four systems were established in 1948 as part of major social reforms following the Second World War. The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care. In England, NHS patients have to pay prescription charges; some, such as those aged over 60 and certain state ben ...
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