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Naphthylpropylaminopentane
1-(2-Naphthyl)-2-propylaminopentane (NPAP), also known as 2-naphthyl-α,''N''-dipropylphenethylamine, is a monoaminergic activity enhancer (MAE) of the α-propylphenethylamine and substituted naphthylaminopropane, naphthylaminopropane families related to phenylpropylaminopentane (PPAP). It is the structural analog, analogue of PPAP in which the phenyl ring has been replaced with a naphthalene ring (chemistry), ring. MAEs are agents that enhance the action potential-mediated neurotransmitter release, release of monoamine neurotransmitters. NPAP is a MAE of norepinephrine and dopamine but not of serotonin. Its potency (pharmacology), potency is similar to that of PPAP. As with PPAP, the (–)-enantiomer of NPAP is more potent as a MAE. Like PPAP, it is inactive as a classical monoamine releasing agent. NPAP was developed by József Knoll and colleagues and was first described in 2001. See also * Methylenedioxyphenylpropylaminopentane (MPAP) * Benzofuranylpropylaminopentane (BPAP) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Naphthylaminopropane
The substituted naphthylethylamines are a class of chemical compounds based on naphthalene. Many naphthylethylamines are naphthylaminopropanes (also known as naphthylisopropylamines) due to the presence of a methyl group at the alpha carbon of the alkyl chain. The naphthylethylamines are derivatives of the phenethylamines, while the naphthylaminopropanes are derivatives of the amphetamines. There are two types of naphthylethylamines based on positional isomerism: 1-naphthylethylamines and 2-naphthylethylamines. Examples of these include 1-naphthylaminopropane (1-NAP) and 2-naphthylaminopropane (2-NAP), respectively. List of substituted naphthylethylamines The substituted napthylethylamines include the following compounds: Additional naphthylethylamines include 4-NEMD, centanafadine (EB-1020), nafimidone, naphazoline, and xaliproden (SR-57746). Some synthetic cannabinoids such as THJ-018 and THJ-2201 are also naphthylethylamines. Related compounds Some related compound ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
