Minoru Shirota
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Minoru Shirota
was a Japanese microbiologist. In the 1930 Shirota identified a strain of lactic acid bacteria that is part of normal gut flora that he originally called ''Lactobacillus casei Shirota,'' which appeared to help contain the growth of harmful bacteria in the gut. The strain was later reclassified as '' Lactobacillus paracasei Shirota''. Lay summary: He founded the company Yakult Honsha in 1935 to sell beverages containing the strain branded Yakult. He died in Tokyo Tokyo (; ja, 東京, , ), officially the Tokyo Metropolis ( ja, 東京都, label=none, ), is the capital and largest city of Japan. Formerly known as Edo, its metropolitan area () is the most populous in the world, with an estimated 37.468 ..., Japan in 1982. References {{DEFAULTSORT:Shirota, Minoru 1899 births 1982 deaths Japanese military doctors Japanese microbiologists People from Iida, Nagano Japanese inventors ...
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Iida, Nagano
is a city in Nagano Prefecture, Japan. , Iida had an estimated population of 101,536, and a population density of 154 persons per km2. The total area of the city is . Iida is an , a municipality designated by the Japanese government to be a model for making large cuts in greenhouse gas emissions towards a low-carbon society. Geography Iida is the southernmost city of Nagano Prefecture. Mount Hijiri at is the highest elevation in the city. Iida lies 90 minutes northeast of the major city of Nagoya by automobile via the Chūō Expressway. The same expressway also provides access to Tokyo, about four hours to the east. The nearest large metropolis to Iida is Nagoya, which is easily accessible by bus (about 2 hours). The larger cities of Matsumoto and Nagano in central and northern Nagano Prefecture are also accessible by bus and train. There is also a bus service to Shinjuku, Tokyo, which takes about four hours. Surrounding municipalities *Nagano Prefecture ** Kamiina District: ...
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Tokyo
Tokyo (; ja, 東京, , ), officially the Tokyo Metropolis ( ja, 東京都, label=none, ), is the capital and largest city of Japan. Formerly known as Edo, its metropolitan area () is the most populous in the world, with an estimated 37.468 million residents ; the city proper has a population of 13.99 million people. Located at the head of Tokyo Bay, the prefecture forms part of the Kantō region on the central coast of Honshu, Japan's largest island. Tokyo serves as Japan's economic center and is the seat of both the Japanese government and the Emperor of Japan. Originally a fishing village named Edo, the city became politically prominent in 1603, when it became the seat of the Tokugawa shogunate. By the mid-18th century, Edo was one of the most populous cities in the world with a population of over one million people. Following the Meiji Restoration of 1868, the imperial capital in Kyoto was moved to Edo, which was renamed "Tokyo" (). Tokyo was devastate ...
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Yakult
is a Japanese sweetened probiotic milk beverage fermented with the bacteria strain '' Lacticaseibacillus casei'' Shirota. It is sold by Yakult Honsha, based in Tokyo. It is distributed through convenience stores and supermarkets in single-serving containers of (depending on the manufacturer) or , often in single-row packs of five or ten. Ingredients Yakult ingredients are water, skimmed milk, glucose-fructose syrup, sucrose, and live ''Lactobacillus casei Shirota'' bacteria. The strain was originally classified as being ''Lactobacillus casei'' but in 2008 it was reclassified as belonging to ''L. paracasei''. Yakult is prepared by adding glucose to skimmed milk and heating the mixture at 90 to 95 °C for about 30 minutes. After letting it cool down to 45 °C, the mixture is inoculated with the lactobacillus and incubated for 6 to 7 days at 37 to 38 °C. After fermentation, water, sugar, gums and lactic acid are added. Health claims In 2006, a panel appoi ...
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Lactic Acid Bacteria
Lactobacillales are an order of gram-positive, low-GC, acid-tolerant, generally nonsporulating, nonrespiring, either rod-shaped (bacilli) or spherical (cocci) bacteria that share common metabolic and physiological characteristics. These bacteria, usually found in decomposing plants and milk products, produce lactic acid as the major metabolic end product of carbohydrate fermentation, giving them the common name lactic acid bacteria (LAB). Production of lactic acid has linked LAB with food fermentations, as acidification inhibits the growth of spoilage agents. Proteinaceous bacteriocins are produced by several LAB strains and provide an additional hurdle for spoilage and pathogenic microorganisms. Furthermore, lactic acid and other metabolic products contribute to the organoleptic and textural profile of a food item. The industrial importance of the LAB is further evidenced by their generally recognized as safe (GRAS) status, due to their ubiquitous appearance in food and thei ...
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Gut Flora
Gut microbiota, gut microbiome, or gut flora, are the microorganisms, including bacteria, archaea, fungi, and viruses that live in the digestive tracts of animals. The gastrointestinal metagenome is the aggregate of all the genomes of the gut microbiota. The gut is the main location of the human microbiome. The gut microbiota has broad impacts, including effects on colonization, resistance to pathogens, maintaining the intestinal epithelium, metabolizing dietary and pharmaceutical compounds, controlling immune function, and even behavior through the gut–brain axis. The microbial composition of the gut microbiota varies across regions of the digestive tract. The colon contains the highest microbial density recorded in any habitat on Earth, representing between 300 and 1000 different species. Bacteria are the largest and to date, best studied component and 99% of gut bacteria come from about 30 or 40 species. Up to 60% of the dry mass of feces is bacteria. Over 99% of the bac ...
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Lactobacillus Casei
''Lacticaseibacillus casei ''is an organism that belongs to the largest genus in the family ''Lactobacillaceae'', a lactic acid bacteria (LAB), that was previously classified as ''Lactobacillus casei-01''. This bacteria has been identified as facultatively anaerobic or microaerophilic, acid-tolerant, non-spore-forming bacteria. The taxonomy of this group has been debated for several years because researchers struggled to differentiate between the strains of ''L. casei'' and ''L. paracasei''. It has recently been accepted as a single species with five subspecies: ''L. casei'' subsp. ''rhamnosus'', ''L. casei'' subsp. ''alactosus'', ''L. casei'' subsp. ''casei'', ''L. casei'' subsp. ''tolerans'', and ''L. casei'' subsp. ''pseudoplantarum''. The taxonomy of this genus was determined according to the phenotypic, physiological, and biochemical similarities. This species is a non-sporing, rod-shaped, gram positive microorganism that can be found within the reproductive and digestive tra ...
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Lactobacillus Paracasei
''Lacticaseibacillus paracasei '' (commonly abbreviated as ''Lc. paracasei'') is a gram-positive, homofermentative species of lactic acid bacteria that are commonly used in dairy product fermentation and as probiotic cultures. ''Lc. paracasei'' is a bacterium that operates by commensalism. It is commonly found in many human habitats such as human intestinal tracts and mouths as well as sewages, silages, and previously mentioned dairy products. The name includes morphology, a rod-shaped (bacillus shape) bacterium with a width of 2.0 to 4.0μm and length of 0.8 to 1.0μm. Strains of ''L. paracasei'' have been isolated from a variety of environments including dairy products, plants or plant fermentations, and from the human and animal gastrointestinal tracts. A protracted refrigeration period before in vitro gastrointestinal transit (GIT) did not affect or influenced very weakly cell resistance . ''Lacticaseibacillus paracasei'' is genotypically and phenotypically closely related ...
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Yakult Honsha
Yakult Honsha is a Japanese company founded in 1955 to sell its flagship product, Yakult—a beverage made using industrial lactic milk, a bacterial strain discovered by Minoru Shirota in the 1920s. Yakult Honsha is a multinational corporation that sells various other products and owns the Tokyo Yakult Swallows baseball team, in addition to the Roaring Raymonds. The company regularly promotes what the ''Financial Times'' called its "idiosyncratic philosophy of 'Shirota-ism'", namely that it should sell its products at an affordable price, and that a healthy intestine promotes longer life. History Since 1963, Yakult has employed women known as "Yakult ladies" (ヤクルトレディー; ''Yakuruto redī'') or "Yakult aunties" (ヤクルトおばさん; ''Yakuruto obasan'') to sell or deliver the products to individuals at their homes while traveling on bicycles or motorcycles. The initiative, meant to utilize Japanese women in the workforce, is responsible for up to 60% of all ...
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1899 Births
Events January 1899 * January 1 ** Spanish rule ends in Cuba, concluding 400 years of the Spanish Empire in the Americas. ** Queens and Staten Island become administratively part of New York City. * January 2 – **Bolivia sets up a customs office in Puerto Alonso, leading to the Brazilian settlers there to declare the Republic of Acre in a revolt against Bolivian authorities. **The first part of the Jakarta Kota–Anyer Kidul railway on the island of Java is opened between Batavia Zuid ( Jakarta Kota) and Tangerang. * January 3 – Hungarian Prime Minister Dezső Bánffy fights an inconclusive duel with his bitter enemy in parliament, Horánszky Nándor. * January 4 – **U.S. President William McKinley's declaration of December 21, 1898, proclaiming a policy of benevolent assimilation of the Philippines as a United States territory, is announced in Manila by the U.S. commander, General Elwell Otis, and angers independence activists who had fought against ...
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1982 Deaths
__NOTOC__ Year 198 (CXCVIII) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar. At the time, it was known as the Year of the Consulship of Sergius and Gallus (or, less frequently, year 951 ''Ab urbe condita''). The denomination 198 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire *January 28 **Publius Septimius Geta, son of Septimius Severus, receives the title of Caesar. **Caracalla, son of Septimius Severus, is given the title of Augustus. China *Winter – Battle of Xiapi: The allied armies led by Cao Cao and Liu Bei defeat Lü Bu; afterward Cao Cao has him executed. By topic Religion * Marcus I succeeds Olympianus as Patriarch of Constantinople (until 211). Births * Lu Kai (or Jingfeng), Chinese official and general (d. 269) * Quan Cong, Chinese general and advisor (d ...
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Japanese Military Doctors
Japanese may refer to: * Something from or related to Japan, an island country in East Asia * Japanese language, spoken mainly in Japan * Japanese people, the ethnic group that identifies with Japan through ancestry or culture ** Japanese diaspora, Japanese emigrants and their descendants around the world * Japanese citizens, nationals of Japan under Japanese nationality law ** Foreign-born Japanese, naturalized citizens of Japan * Japanese writing system, consisting of kanji and kana * Japanese cuisine, the food and food culture of Japan See also * List of Japanese people * * Japonica (other) * Japonicum * Japonicus * Japanese studies Japanese studies (Japanese: ) or Japan studies (sometimes Japanology in Europe), is a sub-field of area studies or East Asian studies involved in social sciences and humanities research on Japan. It incorporates fields such as the study of Japanese ... {{disambiguation Language and nationality disambiguation pages ...
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Japanese Microbiologists
Japanese may refer to: * Something from or related to Japan, an island country in East Asia * Japanese language, spoken mainly in Japan * Japanese people, the ethnic group that identifies with Japan through ancestry or culture ** Japanese diaspora, Japanese emigrants and their descendants around the world * Japanese citizens, nationals of Japan under Japanese nationality law ** Foreign-born Japanese, naturalized citizens of Japan * Japanese writing system, consisting of kanji and kana * Japanese cuisine, the food and food culture of Japan See also * List of Japanese people * * Japonica (other) * Japonicum * Japonicus * Japanese studies Japanese studies (Japanese: ) or Japan studies (sometimes Japanology in Europe), is a sub-field of area studies or East Asian studies involved in social sciences and humanities research on Japan. It incorporates fields such as the study of Japanese ... {{disambiguation Language and nationality disambiguation pages ...
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