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Mieczysław Mąkosza
Mieczysław Józef Mąkosza (born 16 November 1934) is a Polish chemist specializing in organic synthesis and investigation of organic mechanisms. Along with Jerzy Winiarski he is credited for the discovery of the aromatic vicarious nucleophilic substitution, VNS. He also contributed to the discovery of phase transfer catalysis reactions. From 1979 to 2005 he was director of the Institute of Organic Chemistry of the Polish Academy of Sciences The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars a .... References 1934 births 20th-century Polish chemists Living people Recipients of the State Award Badge (Poland) 21st-century Polish chemists {{Poland-scientist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organic Synthesis
Organic synthesis is a branch of chemical synthesis concerned with the construction of organic compounds. Organic compounds are molecules consisting of combinations of covalently-linked hydrogen, carbon, oxygen, and nitrogen atoms. Within the general subject of organic synthesis, there are many different types of synthetic routes that can be completed including total synthesis, Enantioselective synthesis, stereoselective synthesis, automated synthesis, and many more. Additionally, in understanding organic synthesis it is necessary to be familiar with the methodology, techniques, and applications of the subject. Total synthesis A total synthesis refers to the complete chemical synthesis of molecules from simple, Precursor (chemistry), natural precursors. Total synthesis is accomplished either via a linear or convergent approach. In a Linear synthesis, ''linear'' synthesis—often adequate for simple structures—several steps are performed sequentially until the molecule is com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Warsaw University Of Technology
The Warsaw University of Technology () is one of the leading institutes of technology in Poland and one of the largest in Central Europe. It employs 2,453 teaching faculty, with 357 professors (including 145 titular professors). The student body numbers 36,156 (as of 2011), mostly full-time. Its 19 Faculty (division), faculties (divisions) covering almost all fields of science and technology are located in Warsaw, with the exception of one, which is in Płock. The Warsaw University of Technology has about 5,000 graduates per year. According to the 2008 ''Rzeczpospolita (newspaper), Rzeczpospolita'' newspaper survey, engineers govern Polish companies. Warsaw Tech alums make up the highest percentage of Polish managers and executives. Every ninth president among the top 500 corporations in Poland is a graduate of the Warsaw University of Technology. Professor Kurnik, the rector, explained that the school provides a solid basis for the performance of managers by equipping its student ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polish Academy Of Sciences
The Polish Academy of Sciences (, PAN) is a Polish state-sponsored institution of higher learning. Headquartered in Warsaw, it is responsible for spearheading the development of science across the country by a society of distinguished scholars and a network of research institutes. It was established in 1951, during the early period of the Polish People's Republic following World War II. History The Polish Academy of Sciences is a Polish state-sponsored institution of higher learning, headquartered in Warsaw, that was established by the merger of earlier science societies, including the Polish Academy of Learning (''Polska Akademia Umiejętności'', abbreviated ''PAU''), with its seat in Kraków, and the Warsaw Society of Friends of Learning (Science), which had been founded in the late 18th century. The Polish Academy of Sciences functions as a learned society acting through an elected assembly of leading scholars and research institutions. The Academy has also, operating throug ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leningrad University
Saint Petersburg State University (SPBGU; ) is a public university, public research university in Saint Petersburg, Russia, and one of the oldest and most prestigious universities in Russia. Founded in 1724 by a decree of Peter the Great, the university from the beginning has had a focus on fundamental research in science, engineering and humanities. During the Soviet period, it was known as Leningrad State University (). It was renamed after Andrei Zhdanov in 1948 and was officially called "Leningrad State University, named after A. A. Zhdanov and decorated with the Order of Lenin and the Order of the Red Banner of Labour." Zhdanov's was removed in 1989 and Leningrad in the name was officially replaced with Saint Petersburg in 1992. It is made up of 24 specialized faculties (departments) and institutes, the Academic Gymnasium, the Medical College, the College of Physical Culture and Sports, Economics and Technology. The university has two primary campuses: one on Vasilievsky Isl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vicarious Nucleophilic Substitution
In organic chemistry, the vicarious nucleophilic substitution is a special type of nucleophilic aromatic substitution in which a nucleophile replaces a hydrogen atom on the aromatic ring and not leaving groups such as halogen substituents which are ordinarily encountered in SNAr. This reaction type was reviewed in 1987 by Polish chemists Mieczysław Mąkosza and Jerzy Winiarski.''Synthesis of heterocyclic compounds via vicarious nucleophilic substitution of hydrogen'' Mieczysław Mąkosza Pure Appl. Chem., Vol. 69, No. 3, pp. 559-564, 1997''Article link It is typically encountered with nitroarenes and especially with nucleophiles, resulting in alkylated arenes: the new substituent can take the ''ortho'' or ''para'' positions, reversing the selectivity for the ''meta'' position that is usually observed with such compounds under electrophilic substitution. Carbon nucleophiles carry an electron-withdrawing group and a leaving group: the nucleophile attacks the aromatic ring, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phase Transfer Catalysis
In chemistry, a phase-transfer catalyst or PTC is a catalyst that facilitates the transition of a reactant from one phase into another phase where reaction occurs. Phase-transfer catalysis is a special form of catalysis and can act through homogeneous catalysis or heterogeneous catalysis methods depending on the catalyst used. Ionic reactants are often soluble in an aqueous phase but insoluble in an organic phase in the absence of the phase-transfer catalyst. The catalyst functions like a detergent for solubilizing the salts into the organic phase. Phase-transfer catalysis refers to the acceleration of the reaction upon the addition of the phase-transfer catalyst. PTC is widely exploited industrially.Marc Halpern "Phase-Transfer Catalysis" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. Polyesters for example are prepared from acyl chlorides and bisphenol-A. Phosphothioate-based pesticides are generated by PTC-catalyzed alkylation of phosphothioates ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polish People
Polish people, or Poles, are a West Slavic ethnic group and nation who share a common History of Poland, history, Culture of Poland, culture, the Polish language and are identified with the country of Poland in Central Europe. The preamble to the Constitution of the Republic of Poland defines the Polish nation as comprising all the citizenship, citizens of Poland, regardless of heritage or ethnicity. The majority of Poles adhere to Roman Catholicism. The population of self-declared Poles in Poland is estimated at 37,394,000 out of an overall population of 38,512,000 (based on the 2011 census), of whom 36,522,000 declared Polish alone. A wide-ranging Polish diaspora (the ''Polish diaspora, Polonia'') exists throughout Eurasia, the Americas, and Australasia. Today, the largest urban concentrations of Poles are within the Warsaw metropolitan area and the Katowice urban area. Ethnic Poles are considered to be the descendants of the ancient West Slavic Lechites and other tribes t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a graduated scientist trained in the study of chemistry, or an officially enrolled student in the field. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of Chemistry#Subdisciplines, subdisciplines of chemistry. Materials science, Materials scientists and metallurgists sha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vicarious Nucleophilic Substitution
In organic chemistry, the vicarious nucleophilic substitution is a special type of nucleophilic aromatic substitution in which a nucleophile replaces a hydrogen atom on the aromatic ring and not leaving groups such as halogen substituents which are ordinarily encountered in SNAr. This reaction type was reviewed in 1987 by Polish chemists Mieczysław Mąkosza and Jerzy Winiarski.''Synthesis of heterocyclic compounds via vicarious nucleophilic substitution of hydrogen'' Mieczysław Mąkosza Pure Appl. Chem., Vol. 69, No. 3, pp. 559-564, 1997''Article link It is typically encountered with nitroarenes and especially with nucleophiles, resulting in alkylated arenes: the new substituent can take the ''ortho'' or ''para'' positions, reversing the selectivity for the ''meta'' position that is usually observed with such compounds under electrophilic substitution. Carbon nucleophiles carry an electron-withdrawing group and a leaving group: the nucleophile attacks the aromatic ring, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phase Transfer Catalysis
In chemistry, a phase-transfer catalyst or PTC is a catalyst that facilitates the transition of a reactant from one phase into another phase where reaction occurs. Phase-transfer catalysis is a special form of catalysis and can act through homogeneous catalysis or heterogeneous catalysis methods depending on the catalyst used. Ionic reactants are often soluble in an aqueous phase but insoluble in an organic phase in the absence of the phase-transfer catalyst. The catalyst functions like a detergent for solubilizing the salts into the organic phase. Phase-transfer catalysis refers to the acceleration of the reaction upon the addition of the phase-transfer catalyst. PTC is widely exploited industrially.Marc Halpern "Phase-Transfer Catalysis" in Ullmann's Encyclopedia of Industrial Chemistry 2002, Wiley-VCH, Weinheim. Polyesters for example are prepared from acyl chlorides and bisphenol-A. Phosphothioate-based pesticides are generated by PTC-catalyzed alkylation of phosphothioates ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gazeta Wyborcza
(; ''The Electoral Gazette'' in English) is a Polish nationwide daily newspaper based in Warsaw, Poland. It was launched on 8 May 1989 on the basis of the Polish Round Table Agreement and as a press organ of the Solidarity (Polish trade union), trade union "Solidarity" in the election campaign before the Contract Sejm. Initially created to cover Poland's first partially free parliamentary elections, it rapidly grew into a major publication, reaching a circulation of over 500,000 copies at its peak in the 1990s. It is published by Agora (company), Agora, with its original editor-in-chief Adam Michnik, appointed by Lech Wałęsa, is one of Poland's newspaper of record, newspapers of record, covering the gamut of political, international and general news from a Leftism, left-Liberalism, liberal perspective. ''Gazeta Wyborcza'' also publishes thematic supplements addressing topics such as economy, law, education, and health, including ''Duży Format'', ''Co Jest Grane 24'', and ''Wys ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1934 Births
Events January–February * January 1 – The International Telecommunication Union, a specialist agency of the League of Nations, is established. * January 15 – The 8.0 1934 Nepal–Bihar earthquake, Nepal–Bihar earthquake strikes Nepal and Bihar with a maximum Mercalli intensity scale, Mercalli intensity of XI (''Extreme''), killing an estimated 6,000–10,700 people. * February 6 – 6 February 1934 crisis, French political crisis: The French far-right leagues rally in front of the Palais Bourbon, in an attempted coup d'état against the French Third Republic, Third Republic. * February 9 ** Gaston Doumergue forms a new government in France. ** Second Hellenic Republic, Greece, Kingdom of Romania, Romania, Turkey and Kingdom of Yugoslavia, Yugoslavia form the Balkan Pact. * February 12–February 15, 15 – Austrian Civil War: The Fatherland Front (Austria), Fatherland Front consolidates its power in a series of clashes across the country. * February 16 – The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
