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Midgut
The midgut is the portion of the human embryo from which almost all of the small intestine and approximately half of the large intestine develop. After it bends around the superior mesenteric artery, it is called the "midgut loop". It comprises the portion of the alimentary canal from the end of the foregut at the opening of the bile duct to the hindgut, about two-thirds of the way through the transverse colon. In addition to representing an important distinction in embryologic development, the tissues derived from the midgut additionally have distinct vascular supply and innervation patterns in the adult gastrointestinal system. In the embryo During standard human embryonic development, the midgut undergoes a process known as physiological herniation around week 6, when rapid growth forces the midgut to temporarily exit the abdominal cavity and reside in the extra-abdominal umbilical cord. At this stage, the midgut begins its initial counterclockwise rotation around the ...
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Intestinal Malrotation
Intestinal malrotation is a congenital anomaly of rotation of the midgut. It occurs during the first trimester as the fetal gut undergoes a complex series of growth and development. Malrotation can lead to a dangerous complication called volvulus, in which cases emergency surgery is indicated. Malrotation can refer to a spectrum of abnormal intestinal positioning, often including: * The small intestine found predominantly on the right side of the abdomen * The cecum displaced from its usual position in the right lower quadrant into the epigastrium or right hypochondrium * An absent or displaced ligament of Treitz * Fibrous peritoneal bands called bands of Ladd running across the vertical portion of the duodenum * An unusually narrow, stalk-like mesentery The position of the intestines, narrow mesentery and Ladd's bands can contribute to several severe gastrointestinal conditions. The narrow mesentery predisposes some cases of malrotation to midgut volvulus, a twisting of the enti ...
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Mesentery
In human anatomy, the mesentery is an Organ (anatomy), organ that attaches the intestines to the posterior abdominal wall, consisting of a double fold of the peritoneum. It helps (among other functions) in storing Adipose tissue, fat and allowing blood vessels, lymphatics, and nerves to supply the intestines. The (the part of the mesentery that attaches the colon to the abdominal wall) was formerly thought to be a fragmented structure, with all named parts—the ascending, transverse, descending, and sigmoid mesocolons, the mesoappendix, and the mesorectum—separately terminating their insertion into the posterior abdominal wall. However, in 2012, new microscopy, microscopic and electron microscope, electron microscopic histology, examinations showed the mesocolon to be a single structure derived from the duodenojejunal flexure and extending to the distal mesorectal layer. Thus the mesentery is an internal organ. Structure The mesentery of the small intestine arises from th ...
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Duodenum
The duodenum is the first section of the small intestine in most vertebrates, including mammals, reptiles, and birds. In mammals, it may be the principal site for iron absorption. The duodenum precedes the jejunum and ileum and is the shortest part of the small intestine. In humans, the duodenum is a hollow jointed tube about long connecting the stomach to the jejunum, the middle part of the small intestine. It begins with the duodenal bulb, and ends at the duodenojejunal flexure marked by the suspensory muscle of duodenum. The duodenum can be divided into four parts: the first (superior), the second (descending), the third (transverse) and the fourth (ascending) parts. Overview The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear, and the terms ''anterior intestine'' or ''proximal intestine'' may be used instead of duodenum. In mammals the d ...
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Cecum
The cecum ( caecum, ; plural ceca or caeca, ) is a pouch within the peritoneum that is considered to be the beginning of the large intestine. It is typically located on the right side of the body (the same side of the body as the appendix (anatomy), appendix, to which it is joined). The term stems from the Latin ''wikt:caecus, caecus'', meaning "blindness, blind". It receives chyme from the ileum, and connects to the ascending colon of the large intestine. It is separated from the ileum by the ileocecal valve (ICV), also called Bauhin's valve. It is also separated from the Large intestine#Structure, colon by the cecocolic junction. While the cecum is usually intraperitoneal, the ascending colon is Retroperitoneal space, retroperitoneal. In herbivores, the cecum stores food material where bacteria are able to break down the cellulose. In humans, the cecum is involved in absorption of Salt (chemistry), salts and Electrolyte, electrolytes and lubricates the solid waste that pas ...
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Foregut
The foregut in humans is the anterior part of the alimentary canal, from the distal esophagus to the first half of the duodenum, at the entrance of the bile duct. Beyond the stomach, the foregut is attached to the abdominal walls by mesentery. The foregut arises from the endoderm, developing from the folding primitive gut, and is developmentally distinct from the midgut and hindgut. Although the term “foregut” is typically used in reference to the anterior section of the primitive gut, components of the adult gut can also be described with this designation. Pain in the epigastric region, just below the intersection of the ribs, typically refers to structures in the adult foregut. Adult foregut Components * Esophagus * Respiratory tract (lower respiratory tract) * Stomach * Duodenum (up to ampulla of vater) * Liver * Gallbladder * Pancreas * Spleen – The spleen arises from the mesodermal dorsal mesentery (the foregut arises from the endoderm not mesoderm). But the sp ...
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Small Intestine
The small intestine or small bowel is an organ (anatomy), organ in the human gastrointestinal tract, gastrointestinal tract where most of the #Absorption, absorption of nutrients from food takes place. It lies between the stomach and large intestine, and receives bile and pancreatic juice through the pancreatic duct to aid in digestion. The small intestine is about long and folds many times to fit in the abdomen. Although it is longer than the large intestine, it is called the small intestine because it is narrower in diameter. The small intestine has three distinct regions – the duodenum, jejunum, and ileum. The duodenum, the shortest, is where preparation for absorption through small finger-like protrusions called intestinal villus, intestinal villi begins. The jejunum is specialized for the absorption through its lining by enterocytes: small nutrient particles which have been previously digested by enzymes in the duodenum. The main function of the ileum is to absorb vitami ...
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Large Intestine
The large intestine, also known as the large bowel, is the last part of the gastrointestinal tract and of the Digestion, digestive system in tetrapods. Water is absorbed here and the remaining waste material is stored in the rectum as feces before being removed by defecation. The Colon (anatomy), colon (progressing from the ascending colon to the transverse colon, transverse, the descending colon, descending and finally the sigmoid colon) is the longest portion of the large intestine, and the terms "large intestine" and "colon" are often used interchangeably, but most sources define the large intestine as the combination of the cecum, colon, rectum, and anal canal. Some other sources exclude the anal canal. In humans, the large intestine begins in the right iliac region of the pelvis, just at or below the waist, where it is joined to the end of the small intestine at the cecum, via the ileocecal valve. It then continues as the colon ascending colon, ascending the abdomen, across t ...
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Ileum
The ileum () is the final section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms posterior intestine or distal intestine may be used instead of ileum. Its main function is to absorb vitamin B12, vitamin B12, bile salts, and whatever products of digestion that were not absorbed by the jejunum. The ileum follows the duodenum and jejunum and is separated from the cecum by the ileocecal valve (ICV). In humans, the ileum is about 2–4 m long, and the pH is usually between 7 and 8 (neutral or slightly base (chemistry), basic). ''Ileum'' is derived from the Greek word εἰλεός (eileós), referring to a medical condition known as ileus. Structure The ileum is the third and final part of the small intestine. It follows the jejunum and ends at the ileocecal junction, where the wikt:terminal, terminal ileum communicates with the cecum of the large intestine thro ...
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Vermiform Appendix
The appendix (: appendices or appendixes; also vermiform appendix; cecal (or caecal, cæcal) appendix; vermix; or vermiform process) is a finger-like, blind-ended tube connected to the cecum, from which it develops in the embryo. The cecum is a pouch-like structure of the large intestine, located at the junction of the small and the large intestines. The term " vermiform" comes from Latin and means "worm-shaped". The appendix was once considered a vestigial organ, but this view has changed since the early 2000s. Research suggests that the appendix may serve as a reservoir for beneficial gut bacteria. Structure The human appendix averages in length, ranging from . The diameter of the appendix is , and more than is considered a thickened or inflamed appendix. The longest appendix ever removed was long. The appendix is usually located in the lower right quadrant of the abdomen, near the right hip bone. The base of the appendix is located beneath the ileocecal valve tha ...
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Hepatic Flexure
In the anatomy of the human digestive tract, there are two colic flexures, or curvatures in the transverse colon. The right colic flexure is also known as the hepatic flexure, and the left colic flexure is also known as the splenic flexure. Structure Right colic flexure The right colic flexure or hepatic flexure (as it is next to the liver) is the sharp bend between the ascending colon and the transverse colon. The hepatic flexure lies in the right upper quadrant of the human abdomen The abdomen (colloquially called the gut, belly, tummy, midriff, tucky, or stomach) is the front part of the torso between the thorax (chest) and pelvis in humans and in other vertebrates. The area occupied by the abdomen is called the abdominal .... It receives blood supply from the superior mesenteric artery. Left colic flexure The left colic flexure or splenic flexure (as it is close to the spleen) is the sharp bend between the transverse colon and the descending colon. The splenic ...
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Transverse Colon
In human anatomy, the transverse colon is the longest and most movable part of the Large intestine#Structure, colon. Anatomical position It crosses the abdomen from the ascending colon at the right colic flexure (hepatic flexure) with a downward convexity to the descending colon where it curves sharply on itself beneath the lower end of the spleen forming the left colic flexure (splenic flexure). In its course, it describes an arch, the concavity of which is directed backward and a little upward. Toward its splenic end there is often an abrupt U-shaped curve which may descend lower than the main curve. It is almost completely invested by the peritoneum, and is connected to the inferior border of the pancreas by a large and wide duplicature of that membrane, the transverse mesocolon. It is in relation, by its upper surface, with the liver and gall-bladder, the greater curvature of the stomach, and the lower end of the spleen; by its under surface, with the small intestine; by its ...
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