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MDBZ
Methylenedioxybenzylamphetamine, abbreviated MDBZ, and systematically named 3,4-methylenedioxy-''N''-benzylamphetamine, is a Psychedelics, dissociatives and deliriants, psychedelic drug. It is the ''N''-benzyl derivative of 3,4-methylenedioxyamphetamine (MDA). MDBZ was first synthesized by Alexander Shulgin. In his book ''PiHKAL, PiHKAL (Phenethylamines i Have Known And Loved)'', the minimum dosage is listed as 150 mg, and the duration unknown. Very few data exist about the pharmacological properties, metabolism, and toxicity of MDBZ. In an episode of the British spoof documentary TV show ''Brass Eye'', David Amess MP was fooled into recording a warning against a fictitious new drug called "cake". When asked a parliamentary question about it, the Home Office incorrectly assumed Amess was referring to MDBZ. Legality United Kingdom MDBZ is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act#Class A drugs, Drugs controlled by the UK Misuse of Drugs Act. See a ...
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Methylenedioxyphenethylamines
The substituted methylenedioxyphenethylamines (abbreviated as MDxx) represent a diverse chemical class of compounds derived from phenethylamines. This category encompasses numerous Psychoactive drug, psychoactive substances with Empathogen, entactogenic, Psychedelic drug, psychedelic, and/or stimulant properties, in addition to entheogens. These compounds find application as research chemicals, designer drugs, and recreational substances. The base chemical compound, compound of the MDxx class is methylenedioxyphenethylamine, 3,4-methylenedioxyphenethylamine (MDPEA), and the prototypical agent of this class is MDMA, 3,4-methylenedioxy-''N''-methylamphetamine (MDMA; "ecstasy"). Other notable MDxx class substances include 3,4-methylenedioxyamphetamine (MDA), methylenedioxyethylamphetamine, 3,4-methylenedioxy-''N''-ethylamphetamine (MDEA; "Eve"), methylbenzodioxolylbutanamine, ''N''-methyl-1,3-benzodioxolylbutanamine (MBDB; "Eden"), and methylenedioxymethcathinone, 3,4-methylenedioxy- ...
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PiHKAL
''PiHKAL: A Chemical Love Story'' is a book by Alexander Shulgin and Ann Shulgin published in 1991. The subject of the work is Psychoactive drug, psychoactive phenethylamine Derivative (chemistry), chemical derivatives, notably those that act as psychedelic drug, psychedelics and/or empathogen-entactogens. The main title, PiHKAL, is an acronym that stands for "Phenethylamines I Have Known and Loved". The book is arranged into two parts, the first part being a fictionalized autobiography of the couple and the second part describing 179 different psychedelic compounds (most of which Shulgin discovered himself), including detailed synthesis instructions, bioassays, dosages, and other commentary. The second part was made freely available by Shulgin on Erowid while the first part is available only in the printed text. While the reactions described are beyond the ability of people with a basic chemistry education, some tend to emphasize techniques that do not require difficult-to-ob ...
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Benzylone
Benzylone (also known as 3,4-Methylenedioxy-N-benzylcathinone or BMDP), is a recreational designer drug from the substituted cathinone family, with stimulant effects. It has been commonly encountered in seizures of street drug samples but appears to have relatively low potency on its own, being mainly found as a component of mixtures with other related drugs. See also * Benzedrone * Benzphetamine * MDBZ * Methylone Methylone, also known as 3,4-methylenedioxy-''N''-methylcathinone (MDMC), is an entactogen and stimulant drug of the amphetamine, cathinone, and benzodioxole families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is th ... * Ethylone * Butylone * Eutylone * Pentylone * Ephylone * Isohexylone * N-Ethylhexylone References Cathinones Designer drugs {{nervous-system-drug-stub ...
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Psychedelics, Dissociatives And Deliriants
Hallucinogens, also known as psychedelics, entheogens, or historically as psychotomimetics, are a large and diverse class of psychoactive drugs that can produce altered states of consciousness characterized by major alterations in thought, mood, and perception as well as other changes. Hallucinogens are often categorized as either being psychedelics, dissociatives, or deliriants, but not all hallucinogens fall into these three classes. Examples of hallucinogens include psychedelics or serotonin 5-HT2A receptor agonists like LSD, psilocybin, mescaline, and DMT; dissociatives or NMDA receptor antagonists like ketamine, PCP, DXM, and nitrous oxide; deliriants or antimuscarinics like scopolamine and diphenhydramine; cannabinoids or cannabinoid CB1 receptor agonists like THC, nabilone, and JWH-018; κ-opioid receptor agonists like salvinorin A and pentazocine; GABAA receptor agonists like muscimol and gaboxadol; and oneirogens like ibogaine and harmaline, among ...
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Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. He is acknowledged to have introduced to broader use, in the late 1970s, the previously-synthesized compound MDMA ("ecstasy"), in research psychopharmacology and in combination with conventional therapy, the latter through presentations and academic publications, including to psychologists; and for the rediscovery, occasional discovery, and regular synthesis and personal use and distribution, of possibly hundreds of Psychoactive drug, psychoactive compounds (for their Psychedelic drug, psychedelic and MDMA-like empathogenic bioactivity, bioactivities). As such, Shulgin is seen both as a pioneering and a controversi ...
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Brass Eye
''Brass Eye'' (stylised as brassEYE) is a British satirical television series parodying current affairs news programming. A series of six episodes aired on Channel 4 in 1997, and a further episode in 2001. The series was created and presented by Chris Morris, written by Morris, David Quantick, Peter Baynham, Jane Bussmann, Arthur Mathews, Graham Linehan and Charlie Brooker and directed by Michael Cumming. Overview Originally planned as a spin-off from '' The Day Today'' (1994), the pilot (then called ''Torque tv™'') was passed on by the BBC. Channel 4 commissioned a new pilot, which would be called ''Brass Eye''. The name mixes together the titles of two popular current affairs shows, ('' Brass Tacks'' and ''Public Eye''), while the term "brass eye" is also British slang for the anus. The series satirised media portrayal of social ills, in particular sensationalism, unsubstantiated establishmentarian theory masquerading as fact, and creation of moral panics, and is a ...
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David Amess
Sir David Anthony Andrew Amess ( ; 26 March 1952 – 15 October 2021) was a British politician who served as Member of Parliament (United Kingdom), Member of Parliament (MP) for Southend West from 1997 until Murder of David Amess, his murder in 2021. He previously served as MP for Basildon (UK Parliament constituency), Basildon from 1983 to 1997. A member of the Conservative Party (UK), Conservative Party, he was a Catholic Church in England and Wales, Catholic with socially conservative political views, and was in favour of Britain leaving the European Union. Born and raised in Essex, Amess studied economics and government at Bournemouth University and then had short careers as a primary school teacher, underwriter and recruitment consultant. He was elected a Conservative councillor for London Borough of Redbridge, Redbridge in 1982 and MP for Basildon at the 1983 United Kingdom general election, 1983 general election. His position was seen as a Bellwether#United Kingdom, bellw ...
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Hansard
''Hansard'' is the transcripts of parliamentary debates in Britain and many Commonwealth of Nations, Commonwealth countries. It is named after Thomas Curson Hansard (1776–1833), a London printer and publisher, who was the first official printer to the Parliament of the United Kingdom, Parliament at Westminster. Origins Though the history of the ''Hansard'' began in the British Parliament, each of Britain's colonies developed a separate and distinctive history. Before 1771, the British Parliament had long been a highly secretive body. The official record of the actions of the House was publicly available but there was no record of the debates. The publication of remarks made in the House became a breach of parliamentary privilege, punishable by the two Houses of Parliament (UK), Houses of Parliament. As the populace became interested in parliamentary debates, more independent newspapers began publishing unofficial accounts of them. The many penalties implemented by the governmen ...
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Drugs Controlled By The UK Misuse Of Drugs Act
The Misuse of Drugs Act 1971 (c. 38) is an act of the Parliament of the United Kingdom. It represents action in line with treaty commitments under the Single Convention on Narcotic Drugs, the Convention on Psychotropic Substances, and the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances. Offences under the act include: * Possession of a controlled drug unlawfully * Possession of a controlled drug with intent to supply it * Supplying or offering to supply a controlled drug (even where no charge is made for the drug) * Allowing premises you occupy or manage to be used unlawfully for the purpose of producing or supplying controlled drugs The act establishes the Home Secretary as the principal authority in a drug licensing system. Therefore, for example, various opiates are available legally as prescription-only medicines, and cannabis (hemp) may be grown under licence for 'industrial purposes'. The ( SI 2001/3998), created under ...
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Benzphetamine
Benzphetamine, sold under the brand name Didrex among others, is an amphetamine-type stimulant and appetite suppressant used short-term for weight loss along with a doctor-approved, reduced-calorie diet, exercise, and behavioral program. It is prescribed for obesity to people who have been unable to lose weight through exercise and dieting alone. It is a prodrug of dextromethamphetamine and dextroamphetamine. Mechanism of Action Benzphetamine promotes weight loss by reducing appetite and slightly increasing metabolism. It is the parent compound of clobenzorex, the latter of which is not subject to the Federal Analogue Act, nor scheduled per the Controlled Substances Act of 1970. Contraindications Benzphetamine is contraindicated in patients with advanced arteriosclerosis, symptomatic cardiovascular disease, moderate to severe hypertension, hyperthyroidism, known hypersensitivity or idiosyncrasy to sympathomimetic amines, and glaucoma, or who have recently used a monoami ...
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Phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter in the human central nervous system. In mammals, phenethylamine is produced from the amino acid L-phenylalanine by the enzyme aromatic L-amino acid decarboxylase via enzymatic decarboxylation. In addition to its presence in mammals, phenethylamine is found in many other organisms and foods, such as chocolate, especially after microbial fermentation. Phenethylamine is sold as a dietary supplement for purported mood and weight loss-related therapeutic benefits; however, in orally ingested phenethylamine, a significant amount is metabolized in the small intestine by mon ...
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