KRT72
KRT72 is a keratin gene. It is responsible for hair formation, and it encodes a protein present in the inner root sheath of hair follicle The hair follicle is an organ found in mammalian skin. It resides in the dermal layer of the skin and is made up of 20 different cell types, each with distinct functions. The hair follicle regulates hair growth via a complex interaction betwe ...s. References * "KRT72 Gene - GeneCards , K2C72 Protein , K2C72 Antibody". ''www.genecards.org''. Retrieved 2022-05-19 {{gene-12-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Keratin
Keratin () is one of a family of structural fibrous proteins also known as ''scleroproteins''. Alpha-keratin (α-keratin) is a type of keratin found in vertebrates. It is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin among vertebrates. Keratin also protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals. Excessive keratinization participate in fortification of certain tissues such as in horns of cattle and rhinos, and armadillos' osteoderm. The only other biological matter known to approximate the toughness of keratinized tissue is chitin. Keratin comes in two types, the primitive, softer forms found in all vertebrates and harder, derived forms found only ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Inner Root Sheath
The inner root sheath or internal root sheath of the hair follicle is located between the outer root sheath and the hair shaft.James, William; Berger, Timothy; Elston, Dirk (2005) ''Andrews' Diseases of the Skin: Clinical Dermatology'' (10th ed.). Saunders. Page 8. . It is made of three layers: Henle's layer, Huxley's layer, and the cuticle. Henle's layer is the outermost layer of the inner root sheath, consisting of a single row of cubical cells. During his original examination Henle believed the layer lacked nuclei because he viewed it at a level where it had already cornified. Huxley's layer is in the middle, made up of approximately two rows of flattened cells with granular protoplasm Protoplasm (; ) is the living part of a cell that is surrounded by a plasma membrane. It is a mixture of small molecules such as ions, monosaccharides, amino acid, and macromolecules such as proteins, polysaccharides, lipids, etc. In some defin .... The cuticle of the root sheath is in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |