|
Joseph Bienaimé Caventou
Joseph Bienaimé Caventou (; 30 June 1795 – 5 May 1877) was a French pharmacist. He was a professor at the École de Pharmacie (School of Pharmacy) in Paris. He collaborated with Pierre-Joseph Pelletier in a Parisian laboratory located behind an apothecary. He was a pioneer in the use of mild solvents to isolate a number of active ingredients from plants, making a study of alkaloids from vegetables. Among their successes were the isolation of the following compounds: Quinine sulfate later proved to be an important remedy for the disease malaria. Quinine is the active anti-malarial ingredient in the bark of cinchona tree. Neither of the partners chose to patent their discovery of this compound, releasing it for everybody to use. In 1823 they discovered nitrogen in alkaloid compounds. Other compounds they discovered include colchicine and veratrine. The crater Caventou on the Moon The Moon is Earth's only natural satellite. It Orbit of the Moon, orbits around E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saint-Omer
Saint-Omer (; ; Picard: ''Saint-Onmé'') is a commune and sub-prefecture of the Pas-de-Calais department in France. It is west-northwest of Lille on the railway to Calais, and is located in the Artois province. The town is named after Saint Audomar, who brought Christianity to the area. The canalised section of the river Aa begins at Saint-Omer, reaching the North Sea at Gravelines in northern France. Below its walls, the Aa connects with the Neufossé Canal, which ends at the river Lys. History Saint-Omer first appeared in the writings during the 7th century under the name of Sithiu (Sithieu or Sitdiu), around the Saint-Bertin abbey founded on the initiative of Audomar, (Odemaars or Omer). Omer, bishop of Thérouanne, in the 7th century established the Abbey of Saint Bertin, from which that of Notre-Dame was an offshoot. Rivalry and dissension, which lasted till the French Revolution, soon sprang up between the two monasteries, becoming especially virulent when ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinchonine
Cinchonine is an alkaloid found in ''Cinchona officinalis''. It is used in asymmetric synthesis in organic chemistry. It is a stereoisomer and pseudo-enantiomer of cinchonidine. It is structurally similar to quinine, an antimalarial drug. It is a GLP-1 receptor agonist and therefore has potential as a possible treatment for obesity, type 2 diabetes, and non-alcoholic fatty liver disease. References [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1877 Deaths
Events January * January 1 – Queen Victoria is proclaimed Empress of India by the Royal Titles Act 1876, introduced by Benjamin Disraeli, the Prime Minister of the United Kingdom . * January 8 – Great Sioux War of 1876: Battle of Wolf Mountain – Crazy Horse and his warriors fight their last battle with the United States Cavalry in Montana. * January 20 – The Conference of Constantinople ends, with Ottoman Turkey rejecting proposals of internal reform and Balkan provisions. * January 29 – The Satsuma Rebellion, a revolt of disaffected samurai in Japan, breaks out against the new imperial government; it lasts until September, when it is crushed by a professionally led army of draftees. February * February 17 – Major General Charles George Gordon of the British Army is appointed Governor-General of the Sudan. March * March 2 – Compromise of 1877: The 1876 United States presidential election is resolved with the selection of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1795 Births
Events January–June * January – Central England records its coldest ever month, in the CET records dating back to 1659. * January 14 – The University of North Carolina opens to students at Chapel Hill, becoming the first state university in the United States. * January 16 – War of the First Coalition: Flanders campaign: The French occupy Utrecht, Netherlands. * January 18 – Batavian Revolution in Amsterdam: William V, Prince of Orange, Stadtholder of the Dutch Republic (Republic of the Seven United Netherlands), flees the country. * January 19 – The Batavian Republic is proclaimed in Amsterdam, ending the Dutch Republic (Republic of the Seven United Netherlands). * January 20 – French troops enter Amsterdam. * January 23 – Flanders campaign: Capture of the Dutch fleet at Den Helder: The Dutch fleet, frozen in Zuiderzee, is captured by the French 8th Hussars. * February 7 – The Eleventh Amendment to the United Sta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Saint-Omer
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determination, as i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moon
The Moon is Earth's only natural satellite. It Orbit of the Moon, orbits around Earth at Lunar distance, an average distance of (; about 30 times Earth diameter, Earth's diameter). The Moon rotation, rotates, with a rotation period (lunar day) that is synchronized to its orbital period (Lunar month#Synodic month, lunar month) of 29.5 Earth days. This is the product of Earth's gravitation having tidal forces, tidally pulled on the Moon until one part of it stopped rotating away from the near side of the Moon, near side, making always the same lunar surface face Earth. Conversley, the gravitational pull of the Moon, on Earth, is the main driver of Earth's tides. In geophysical definition of planet, geophysical terms, the Moon is a planetary-mass object or satellite planet. Its mass is 1.2% that of the Earth, and its diameter is , roughly one-quarter of Earth's (about as wide as the contiguous United States). Within the Solar System, it is the List of Solar System objects by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caventou (crater)
Caventou is a tiny lunar impact crater located in the western part of the Mare Imbrium. It is a circular, cup-shaped formation surrounded by the lunar mare. It was named after French chemist Joseph B. Caventou in 1976. Prior to that, it had the designation La Hire D, being associated with the mountain Mons La Hire to the southeast. References * * * * * * * * * * * External links LTO-40A1 Caventou— L&PI topographic map In modern mapping, a topographic map or topographic sheet is a type of map characterized by large- scale detail and quantitative representation of relief features, usually using contour lines (connecting points of equal elevation), but histori ... - partial map undisplayed {{Craters on the Moon: C-F Impact craters on the Moon Mare Imbrium ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Veratrine
Veratridine is a steroidal alkaloid found in plants of the lily family, specifically the genera ''Veratrum'' and ''Schoenocaulon''. Upon absorption through the skin or mucous membranes, it acts as a neurotoxin by binding to and preventing the inactivation of voltage-gated sodium ion channels in heart, nerve, and skeletal muscle cell membranes. Veratridine increases nerve excitability and intracellular Ca2+ concentrations. Isolation Veratridine has been isolated from the seeds of ''Schoenocaulon officinale'' and from the rhizomes of '' Veratrum album.'' Like the other steroidal alkaloids found in these plants and similar ones in the Melanthiaceae family, it is present as part of a glycosidal combination, bonded to carbohydrate moieties. Early isolation methods relied on formation of the nitrate salt and then precipitation of the insoluble sulfate form. Accounts of these efforts date back to 1878, but the first true purification of veratridine is the one carried out in 1953 by Ku ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colchicine
Colchicine is a medication used to prevent and treat gout, to treat familial Mediterranean fever and Behçet's disease, and to reduce the risk of myocardial infarction. The American College of Rheumatology recommends colchicine, nonsteroidal anti-inflammatory drugs (NSAIDs) or steroids in the treatment of gout. Other uses for colchicine include the management of pericarditis. Colchicine is taken by mouth. The injectable route of administration for colchicine can be toxic. In 2008, the US Food and Drug Administration removed all injectable colchicine from the US market. Colchicine has a narrow therapeutic index, so overdosing is a significant risk. Common side effects of colchicine include gastrointestinal upset, particularly at high doses. Severe side effects may include pancytopenia (low blood cell counts) and rhabdomyolysis (damage to skeletal muscle), and the medication can be deadly in overdose. Whether colchicine is safe for use during pregnancy is unclear, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nitrogen
Nitrogen is a chemical element; it has Symbol (chemistry), symbol N and atomic number 7. Nitrogen is a Nonmetal (chemistry), nonmetal and the lightest member of pnictogen, group 15 of the periodic table, often called the Pnictogen, pnictogens. It is a common element in the universe, estimated at Abundance of the chemical elements, seventh in total abundance in the Milky Way and the Solar System. At standard temperature and pressure, two atoms of the element chemical bond, bond to form N2, a colourless and odourless diatomic molecule, diatomic gas. N2 forms about 78% of Atmosphere of Earth, Earth's atmosphere, making it the most abundant chemical species in air. Because of the volatility of nitrogen compounds, nitrogen is relatively rare in the solid parts of the Earth. It was first discovered and isolated by Scottish physician Daniel Rutherford in 1772 and independently by Carl Wilhelm Scheele and Henry Cavendish at about the same time. The name was suggested by French chemist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a Mosquito-borne disease, mosquito-borne infectious disease that affects vertebrates and ''Anopheles'' mosquitoes. Human malaria causes Signs and symptoms, symptoms that typically include fever, Fatigue (medical), fatigue, vomiting, and headaches. In severe cases, it can cause jaundice, Epileptic seizure, seizures, coma, or death. Symptoms usually begin 10 to 15 days after being bitten by an infected ''Anopheles'' mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial Immunity (medical), resistance disappears over months to years if the person has no continuing exposure to malaria. The mosquitoes themselves are harmed by malaria, causing reduced lifespans in those infected by it. Malaria is caused by protozoa, single-celled microorganisms of the genus ''Plasmodium''. It is spread exclusively through bites of infected female ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caffeine
Caffeine is a central nervous system (CNS) stimulant of the methylxanthine chemical classification, class and is the most commonly consumed Psychoactive drug, psychoactive substance globally. It is mainly used for its eugeroic (wakefulness promoting), ergogenic (physical performance-enhancing), or nootropic (cognitive-enhancing) properties. Caffeine acts by blocking the binding of adenosine at a number of adenosine receptor types, inhibiting the centrally depressant effects of adenosine and enhancing the release of acetylcholine. Caffeine has a three-dimensional structure similar to that of adenosine, which allows it to bind and block its receptors. Caffeine also increases Cyclic adenosine monophosphate, cyclic AMP levels through nonselective Phosphodiesterase inhibitor, inhibition of phosphodiesterase, increases calcium release from intracellular stores, and Receptor antagonist, antagonizes GABA receptor, GABA receptors, although these mechanisms typically occur at concentrati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
