|
Jakub PaÅ›
Jakub Paś (born 27 September 1977) is a Polish scientist and developer. He is a doctor of chemistry at the Faculty of Chemistry of Adam Mickiewicz University in Poznań. Early years Paś was born in 1977 in Śrem. He attended No. 4 Primary School in Śrem and the Józef Wybicki High School in Śrem; at that time, he succeeded as a laureate of Polish Mathematics Olympiad. In 2001, he was awarded the MSc in Biotechnology title at the Faculty of Biochemistry of Adam Mickiewicz University in Poznań; his thesis ''Sequential and structural analysis of proteins related to the BcFA (methyl branched-chain fatty acids)'', supervised by Leszek Rychlewski, was awarded distinction in of that year. In 2013, he defended his PhD thesis in chemistry, ''Application and implementation of probabilistic profile-profile comparison methods for protein fold recognition'' (under the supervision of Marcin Hoffmann). He also completed IT Project Management postgradual study on WSB School of Banking ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Åšrem
Śrem () is a town on the Warta river in central Poland. It is the seat of Śrem County in the Greater Poland Voivodeship. As of 1995, the population of Śrem was 29,800. Śrem is to the south of Poznań, a local road junction on the road from Poznań to Rawicz; other roads lead from the town to Września, Leszno and Głuchowo, Kościan County, Głuchowo. The Śrem District has a population of 39,672, of which about 31,000 live in the town of Śrem. History Śrem was founded in the second half of the 10th century in the cradle of the emerging Polish state, when a Gord (archaeology), fortified settlement, which protected the ford across the Warta on an important trade route from Silesia to Poznań, was erected on the right bank of the Warta river, and soon a trade settlement developed on the left bank. It is numbered among the oldest Lechitic languages, Lechitic settlements. Śrem received municipal rights from dukes Bolesław the Pious and Przemysł I of Greater Poland in 1253 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Planck Institute For Molecular Genetics
The Max Planck Institute for Molecular Genetics is a research institute for molecular genetics based in Berlin, Germany. It is part of the Max Planck Institute network of the Max Planck Society for the Advancement of Science. Departments and research groups * Department of Developmental Genetics (Bernhard Herrmann) *Department of Genome Regulation (Alexander Meissner) **Genome Regulation Group (Alexander Meissner) **Stem Cell Chromatin Group (Aydan Bulut-Karslioglu) **Lab for Human Brain & Neural Stem Cell Studies (Yechiel Elkabetz) **Precision Gene Control group (Denes Hnisz) **Cellular Phenotyping Group (Franz-Josef Müller) *Department of Computational Molecular Biology (Martin Vingron) **Transcriptional Regulation Group (Martin Vingron) **Mechanisms of Transcriptional Regulation Group (Sebastiaan H. Meijsing) **Chromatin Structure and Function Group (Sarah Kinkley) **Bioinformatics Group (Ralf Herwig) **Research Group Evolutionary Genomics (Peter Arndt) * Otto Warburg Labor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CI/CD
In software engineering, CI/CD or CICD is the combined practices of continuous integration (CI) and continuous delivery (CD) or, less often, continuous deployment. They are sometimes referred to collectively as continuous development or continuous software development. Components ;Continuous integration: Frequent merging of several small changes into a main branch. ; Continuous delivery: Producing software in short cycles with high speed and frequency so that reliable software can be released at any time, with a simple and repeatable deployment process when deciding to deploy. ; Continuous deployment: Automatic rollout of new software functionality. When these three processes occur in order, they may be described as a "CI/CD pipeline". Motivation CI/CD bridges the gaps between development and operation activities and teams by enforcing automation in building, testing and deployment of applications. CI/CD services compile the incremental code changes made by developers, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intermolecular Force
An intermolecular force (IMF; also secondary force) is the force that mediates interaction between molecules, including the electromagnetic forces of attraction or repulsion which act between atoms and other types of neighbouring particles (e.g. atoms or ions). Intermolecular forces are weak relative to intramolecular forces – the forces which hold a molecule together. For example, the covalent bond, involving sharing electron pairs between atoms, is much stronger than the forces present between neighboring molecules. Both sets of forces are essential parts of force fields frequently used in molecular mechanics. The first reference to the nature of microscopic forces is found in Alexis Clairaut's work ''Théorie de la figure de la Terre,'' published in Paris in 1743. Other scientists who have contributed to the investigation of microscopic forces include: Laplace, Gauss, Maxwell, Boltzmann and Pauling. Attractive intermolecular forces are categorized into the following ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Geometry
Molecular geometry is the three-dimensional arrangement of the atoms that constitute a molecule. It includes the general shape of the molecule as well as bond lengths, bond angles, torsional angles and any other geometrical parameters that determine the position of each atom. Molecular geometry influences several properties of a substance including its reactivity, polarity, phase of matter, color, magnetism and biological activity. The angles between bonds that an atom forms depend only weakly on the rest of a molecule, i.e. they can be understood as approximately local and hence transferable properties. Determination The molecular geometry can be determined by various spectroscopic methods and diffraction methods. IR, microwave and Raman spectroscopy can give information about the molecule geometry from the details of the vibrational and rotational absorbance detected by these techniques. X-ray crystallography, neutron diffraction and electron diffraction can g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogeny
A phylogenetic tree or phylogeny is a graphical representation which shows the evolutionary history between a set of species or Taxon, taxa during a specific time.Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA. In other words, it is a branching diagram or a tree (graph theory), tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. In evolutionary biology, all life on Earth is theoretically part of a single phylogenetic tree, indicating common ancestry. Phylogenetics is the study of phylogenetic trees. The main challenge is to find a phylogenetic tree representing optimal evolutionary ancestry between a set of species or taxa. computational phylogenetics, Computational phylogenetics (also phylogeny inference) focuses on the algorithms involved in finding optimal phylogenetic tree in the phylogenetic landscape. Phylogene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fold Recognition
In molecular biology, protein threading, also known as fold recognition, is a method of protein modeling which is used to model those proteins which have the same fold as proteins of known structures, but do not have homologous proteins with known structure. It differs from the homology modeling method of structure prediction as it (protein threading) is used for proteins which do not have their homologous protein structures deposited in the Protein Data Bank (PDB), whereas homology modeling is used for those proteins which do. Threading works by using statistical knowledge of the relationship between the structures deposited in the PDB and the sequence of the protein which one wishes to model. The prediction is made by "threading" (i.e. placing, aligning) each amino acid in the target sequence to a position in the template structure, and evaluating how well the target fits the template. After the best-fit template is selected, the structural model of the sequence is built base ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Structure Prediction
Protein structure prediction is the inference of the three-dimensional structure of a protein from its amino acid sequence—that is, the prediction of its Protein secondary structure, secondary and Protein tertiary structure, tertiary structure from Protein primary structure, primary structure. Structure prediction is different from the inverse problem of protein design. Protein structure prediction is one of the most important goals pursued by computational biology and addresses Levinthal's paradox. Accurate structure prediction has important applications in medicine (for example, in drug design) and biotechnology (for example, in novel enzyme design). Starting in 1994, the performance of current methods is assessed biannually in the ''Critical Assessment of Structure Prediction'' (CASP) experiment. A continuous evaluation of protein structure prediction web servers is performed by the community project ''Continuous Automated Model EvaluatiOn'' (CAMEO3D). Protein structure a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GSK Plc
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British Multinational corporation, multinational Pharmaceutics, pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a Mergers and acquisitions, merger of Glaxo Wellcome and SmithKline Beecham, which was itself a merger of a number of pharmaceutical companies around the Smith, Kline & French firm. GSK is the tenth largest pharmaceutical company and No. 294 on the 2022 Fortune Global 500, ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm (company), Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck & Co., Merck Sharp & Dohme. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. As of February 2024, it had a Market capitalization, market capitalisation of £69 billion, the eighth largest on the London Stock Exchange. The company developed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marie Skłodowska-Curie Actions
Marie Skłodowska-Curie Actions (MSCA) is a set of major research fellowships created by the European Union/European Commission to support research in the European Research Area (ERA). The Marie Skłodowska-Curie Actions are among Europe's most competitive and prestigious research and innovation fellowships. Established in 1996 as Marie Curie Actions and known since 2014 as Marie Skłodowska-Curie Actions, they aim to foster the career development and further training of researchers at all career stages. The Marie Skłodowska-Curie Actions promote interdisciplinary research and international collaborations, supporting scientists from not only within Europe but also across the globe. Marie Skłodowska-Curie Actions are currently financed through the ninth Framework Programme for Research and Technological Development (called Horizon Europe) and belong to the so-called 'first pillar' of Horizon: "Excellent Science." Through this funding scheme, the European Research Executive Agen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
GPGPU
General-purpose computing on graphics processing units (GPGPU, or less often GPGP) is the use of a graphics processing unit (GPU), which typically handles computation only for computer graphics, to perform computation in applications traditionally handled by the central processing unit (CPU). The use of multiple video cards in one computer, or large numbers of graphics chips, further parallelizes the already parallel nature of graphics processing. Essentially, a GPGPU pipeline is a kind of parallel processing between one or more GPUs and CPUs that analyzes data as if it were in image or other graphic form. While GPUs operate at lower frequencies, they typically have many times the number of cores. Thus, GPUs can process far more pictures and graphical data per second than a traditional CPU. Migrating data into graphical form and then using the GPU to scan and analyze it can create a large speedup. GPGPU pipelines were developed at the beginning of the 21st century for grap ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Supercomputing Conference
The ISC High Performance, formerly known as the International Supercomputing Conference, is a yearly conference on supercomputing which has been held in Europe since 1986. It stands as the oldest supercomputing conference in the world. History In 1986 Professor Dr. Hans Werner Meuer, director of the computer centre and professor for computer science at the University of Mannheim (Germany) co-founded and organized the "Mannheim Supercomputer Seminar" which had 81 participants. This was held yearly and became the annual International Supercomputing Conference and Exhibition (ISC). In 2015, the name was officially changed to ISC High Performance. The conference is attended by speakers, vendors, and researchers from all over the world. Since 1993 the conference has been the venue for one of the twice yearly TOP500 announcements where the fastest 500 supercomputers in the world are named. The other annual announcement is in November at the '' SC Conference'' (The International Confer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
