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Iris Sphincter Muscle
The iris sphincter muscle (pupillary sphincter, pupillary constrictor, circular muscle of iris, circular fibers) is a muscle in the part of the eye called the iris. It encircles the pupil of the iris, appropriate to its function as a constrictor of the pupil. Comparative anatomy This structure is found in vertebrates and in some cephalopods. General structure All the myocytes are of the smooth muscle type. Its dimensions are about 0.75 mm wide by 0.15 mm thick. Mode of action In humans, it functions to constrict the pupil in bright light ( pupillary light reflex) or during accommodation. In lower animals, the muscle cells themselves are photosensitive causing iris action without brain input. Innervation It is controlled by parasympathetic fibers of the muscarinic acetylcholine receptor (M3) that originate from the Edinger–Westphal nucleus, travel along the oculomotor nerve (CN III), synapse in the ciliary ganglion, and then enter the eye through the short c ...
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Iris (anatomy)
In humans and most mammals and birds, the iris (plural: ''irides'' or ''irises'') is a thin, annular structure in the eye, responsible for controlling the diameter and size of the pupil, and thus the amount of light reaching the retina. Eye color is defined by the iris. In optical terms, the pupil is the eye's aperture, while the iris is the diaphragm. Structure The iris consists of two layers: the front pigmented fibrovascular layer known as a stroma and, beneath the stroma, pigmented epithelial cells. The stroma is connected to a sphincter muscle ( sphincter pupillae), which contracts the pupil in a circular motion, and a set of dilator muscles ( dilator pupillae), which pull the iris radially to enlarge the pupil, pulling it in folds. The sphincter pupillae is the opposing muscle of the dilator pupillae. The pupil's diameter, and thus the inner border of the iris, changes size when constricting or dilating. The outer border of the iris does not change size. The constr ...
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Accommodation Reflex
Accommodation may refer to: * A dwelling * A place for temporary lodging * The technique of adaptation to local cultures that the Jesuits used in their missions to spread Christianity among non-Christian peoples. * Reasonable accommodation, a legal doctrine protecting religious minorities or people with disabilities * Accommodation (religion), a theological principle linked to divine revelation within the Christian church * Accommodationism, a judicial interpretation with respect to Church and state issues * Accommodation bridge, a bridge provided to re-connect private land, separated by a new road or railway * Accommodation (law), a term used in US contract law * Accommodation (geology), the space available for sedimentation * Accommodation (eye), the process by which the eye increases optical power to maintain a clear image (focus) on an object as it draws near * Accommodation in psychology, the process by which existing mental structures and behaviors are modified to adapt to ...
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Miosis
Miosis, or myosis (), is excessive constriction of the pupil.Farlex medical dictionary
citing: Mosby's Medical Dictionary, 8th ed. The opposite condition, , is the dilation of the pupil. Anisocoria is the condition of one being more dilated than the other.


Causes


Age

* Senile miosis (a reduction in the size of a person's pupil in old age)


Diseases

* ...
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Iris Dilator Muscle
The iris dilator muscle (pupil dilator muscle, pupillary dilator, radial muscle of iris, radiating fibers), is a smooth muscle of the eye, running radially in the iris and therefore fit as a dilator. The pupillary dilator consists of a spokelike arrangement of modified contractile cells called myoepithelial cells. These cells are stimulated by the sympathetic nervous system. When stimulated, the cells contract, widening the pupil and allowing more light to enter the eye. Structure Innervation It is innervated by the sympathetic system, which acts by releasing noradrenaline, which acts on α1-receptors. page 163 Thus, when presented with a threatening stimulus that activates the fight-or-flight response, this innervation contracts the muscle and dilates the pupil, thus temporarily letting more light reach the retina. The dilator muscle is innervated more specifically by postganglionic sympathetic nerves arising from the superior cervical ganglion as the sympathetic root of cil ...
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Choroid
The choroid, also known as the choroidea or choroid coat, is a part of the uvea, the vascular layer of the eye, and contains connective tissues, and lies between the retina and the sclera. The human choroid is thickest at the far extreme rear of the eye (at 0.2 mm), while in the outlying areas it narrows to 0.1 mm. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract. The structure of the choroid is generally divided into four layers (classified in order of furthest away from the retina to closest): *Haller's layer - outermost layer of the choroid consisting of larger diameter blood vessels; * Sattler's layer - layer of medium diameter blood vessels; *Choriocapillaris - layer of capillaries; and * Bruch's membrane (synonyms: Lamina basalis, Complexus basalis, Lamina vitra) - innermost layer of the choroid. Blood supply There are two circulations of the eye: the r ...
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Sclera
The sclera, also known as the white of the eye or, in older literature, as the tunica albuginea oculi, is the opaque, fibrous, protective, outer layer of the human eye containing mainly collagen and some crucial elastic fiber. In humans, and some other vertebrates, the whole sclera is white, contrasting with the coloured iris, but in most mammals, the visible part of the sclera matches the colour of the iris, so the white part does not normally show while other vertebrates have distinct colors for both of them. In the development of the embryo, the sclera is derived from the neural crest. In children, it is thinner and shows some of the underlying pigment, appearing slightly blue. In the elderly, fatty deposits on the sclera can make it appear slightly yellow. People with dark skin can have naturally darkened sclerae, the result of melanin pigmentation. The human eye is relatively rare for having a pale sclera (relative to the iris). This makes it easier for one individual t ...
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Ciliary Ganglion
The ciliary ganglion is a bundle of nerve parasympathetic ganglion located just behind the eye in the posterior orbit. It is 1–2 mm in diameter and in humans contains approximately 2,500 neurons. The ganglion contains postganglionic parasympathetic neurons. These neurons supply the pupillary sphincter muscle, which constricts the pupil, and the ciliary muscle which contracts to make the lens more convex. Both of these muscles are involuntary since they are controlled by the parasympathetic division of the autonomic nervous system. The ciliary ganglion is one of four parasympathetic ganglia of the head. The others are the submandibular ganglion, pterygopalatine ganglion, and otic ganglion. Structure The ciliary ganglion contains postganglionic parasympathetic neurons that supply the ciliary muscle and the pupillary sphincter muscle. Because of the much larger size of the ciliary muscle, 95% of the neurons in the ciliary ganglion innervate it compared to the pupillary sphin ...
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Oculomotor Nerve
The oculomotor nerve, also known as the third cranial nerve, cranial nerve III, or simply CN III, is a cranial nerve that enters the orbit through the superior orbital fissure and innervates extraocular muscles that enable most movements of the eye and that raise the eyelid. The nerve also contains fibers that innervate the intrinsic eye muscles that enable pupillary constriction and accommodation (ability to focus on near objects as in reading). The oculomotor nerve is derived from the basal plate of the embryonic midbrain. Cranial nerves IV and VI also participate in control of eye movement. Structure The oculomotor nerve originates from the third nerve nucleus at the level of the superior colliculus in the midbrain. The third nerve nucleus is located ventral to the cerebral aqueduct, on the pre-aqueductal grey matter. The fibers from the two third nerve nuclei located laterally on either side of the cerebral aqueduct then pass through the red nucleus. From the red n ...
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Edinger–Westphal Nucleus
The Edinger–Westphal nucleus (accessory oculomotor nucleus, or visceral oculomotor nucleus) is one of two nuclei of the oculomotor nerve. It is located in the midbrain. It contributes the autonomic parasympathetic (i.e. visceral) component to the oculomotor nerve, providing innervation to the iris sphincter muscle and ciliary muscle to mediate the pupillary light reflex and accommodation, respectively. It is composed of parasympathetic pre-ganglionic cell bodies that synapse in the ciliary ganglion. The term "Edinger–Westphal nucleus" also referred to what is now known as the centrally-projecting Edinger–Westphal nucleus, intermingled population of non-preganglionic neurons that do not project to the ciliary ganglion but to various regions throughout the central nervous system.. Anatomy Centrally-projecting Edinger–Westphal nucleus Alternatively, the term Edinger–Westphal nucleus is often used to refer to the adjacent population of non-preganglionic neurons that ...
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Muscarinic Acetylcholine Receptor
Muscarinic acetylcholine receptors, or mAChRs, are acetylcholine receptors that form G protein-coupled receptor complexes in the cell membranes of certain neurons and other cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. Muscarinic receptors are so named because they are more sensitive to muscarine than to nicotine. Their counterparts are nicotinic acetylcholine receptors (nAChRs), receptor ion channels that are also important in the autonomic nervous system. Many drugs and other substances (for example pilocarpine and scopolamine) manipulate these two distinct receptors by acting as selective agonists or antagonists. Function Acetylcholine (ACh) is a neurotransmitter found in the brain, neuromuscular junctions and the autonomic ganglia. Muscarinic receptors are used in the following roles: Recovery receptors ACh is always ...
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Parasympathetic Nervous System
The parasympathetic nervous system (PSNS) is one of the three divisions of the autonomic nervous system, the others being the sympathetic nervous system and the enteric nervous system. The enteric nervous system is sometimes considered part of the autonomic nervous system, and sometimes considered an independent system. The autonomic nervous system is responsible for regulating the body's unconscious actions. The parasympathetic system is responsible for stimulation of "rest-and-digest" or "feed and breed" activities that occur when the body is at rest, especially after eating, including sexual arousal, salivation, lacrimation (tears), urination, digestion, and defecation. Its action is described as being complementary to that of the sympathetic nervous system, which is responsible for stimulating activities associated with the fight-or-flight response. Nerve fibres of the parasympathetic nervous system arise from the central nervous system. Specific nerves include sev ...
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Phys
Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which relates to the order of nature, or, in other words, to the regular succession of events." Physics is one of the most fundamental scientific disciplines, with its main goal being to understand how the universe behaves. "Physics is one of the most fundamental of the sciences. Scientists of all disciplines use the ideas of physics, including chemists who study the structure of molecules, paleontologists who try to reconstruct how dinosaurs walked, and climatologists who study how human activities affect the atmosphere and oceans. Physics is also the foundation of all engineering and technology. No engineer could design a flat-screen TV, an interplanetary spacecraft, or even a better mousetrap without first understanding the basic laws of physics. ...
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