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Irene Tracey
Irene Mary Carmel Tracey (born 30 October 1966) is Vice-Chancellor of the University of Oxford and former Warden of Merton College, Oxford. She is also Professor of Anaesthetic Neuroscience in the Nuffield Department of Clinical Neurosciences and formerly Pro-Vice-Chancellor (without portfolio) at the University of Oxford. She is a co-founder of the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB) now the Wellcome Centre for Human Neuroimaging. Her team’s research is focused on the neuroscience of pain, specifically pain perception and analgesia as well as how anaesthetics produce altered states of consciousness. Her team uses multidisciplinary approaches including neuroimaging. Early life and education Tracey was born at the Radcliffe Infirmary in Oxford and educated at St. Thomas More R.C. Primary School and Gosford Hill School in Kidlington. She completed her undergraduate and graduate studies at Merton College, Oxford in Biochemistry under ...
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Oxford
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to dom ...
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Merton College, Oxford
Merton College (in full: The House or College of Scholars of Merton in the University of Oxford) is one of the constituent colleges of the University of Oxford in England. Its foundation can be traced back to the 1260s when Walter de Merton, chancellor to Henry III and later to Edward I, first drew up statutes for an independent academic community and established endowments to support it. An important feature of de Merton's foundation was that this "college" was to be self-governing and the endowments were directly vested in the Warden and Fellows. By 1274, when Walter retired from royal service and made his final revisions to the college statutes, the community was consolidated at its present site in the south east corner of the city of Oxford, and a rapid programme of building commenced. The hall and the chapel and the rest of the front quad were complete before the end of the 13th century. Mob Quad, one of Merton's quadrangles, was constructed between 1288 and 1378, and ...
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Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio waves to generate images of the organs in the body. MRI does not involve X-rays or the use of ionizing radiation, which distinguishes it from CT and PET scans. MRI is a medical application of nuclear magnetic resonance (NMR) which can also be used for imaging in other NMR applications, such as NMR spectroscopy. MRI is widely used in hospitals and clinics for medical diagnosis, staging and follow-up of disease. Compared to CT, MRI provides better contrast in images of soft-tissues, e.g. in the brain or abdomen. However, it may be perceived as less comfortable by patients, due to the usually longer and louder measurements with the subject in a long, confining tube, though "Open" MRI designs mostly relieve this. Additionally, implants and ...
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Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, in the United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of one of the predecessors of GlaxoSmithKline) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of £29.1 billion in 2020, making it the fourth wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the ''Financial Times'' as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of the largest providers in the world. According to their annual report, the Wellcome Trust spent GBP £1.1Bn on charitable activities across their 2019/2020 financial year. According to the OECD, the Wellcome Trust's financing for 2019 development increased by 22% to US$327 millio ...
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First Class Degree
The British undergraduate degree classification system is a grading structure for undergraduate degrees or bachelor's degrees and integrated master's degrees in the United Kingdom. The system has been applied (sometimes with significant variations) in other countries and regions. History The classification system as currently used in the United Kingdom was developed in 1918. Honours were then a means to recognise individuals who demonstrated depth of knowledge or originality, as opposed to relative achievement in examination conditions. Concern exists about possible grade inflation. It is claimed that academics are under increasing pressure from administrators to award students good marks and grades with little regard for those students' actual abilities, in order to maintain their league table rankings. The percentage of graduates who receive a First (First Class Honours) has grown from 7% in 1997 to 26% in 2017, with the rate of growth sharply accelerating toward the end of ...
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George Radda
Sir George Charles Radda ( hu, György Károly Radda; born 9 June 1936) is a Hungarian - British chemist. In 1957, he attended Merton College, Oxford, to study chemistry, having set aside an earlier interest in literary criticism. His early work was concerned with the development and use of fluorescent probes for the study of structure and function of membranes and enzymes. He became interested in using spectroscopic methods including nuclear magnetic resonance (NMR) to study complex biological material. In 1974, his research paper was the first to introduce the use of NMR to study tissue metabolites. In 1981, he and his colleagues published the first scientific report on the clinical application of his work. This resulted in the installation of a magnet large enough to accommodate the whole human body for NMR investigations in 1983 at the John Radcliffe Hospital in Oxford. In 1982, Radda published about the relationship between deoxygenated haemoglobin and the NMR signal. F ...
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Eric Newsholme
Eric Arthur Newsholme (19 May 1935 - 17 March 2011) was a biochemist who specialised in human metabolism. He was a fellow of Merton College, Oxford, from 1973 until his retirement in 1995, and published a number of seminal textbooks and research papers. Life and career Newsholme was born in Liverpool on 19 May 1935, and was brought up in the city's West Derby suburb. In 1955 he went up to Magdalene College, Cambridge to read Natural Sciences, and then to study for his PhD in Biochemistry under the supervision of Philip Randle. In 1961 he published his first full paper in the ''Biochemical Journal'' (on the regulation of glucose uptake by muscle, co-authored with Philip Randle); this was to be followed by more than 100 papers published in that journal, around 20 of these have gone on to be recognized as seminal papers by the research community. After completing his doctorate, in 1964 he moved to the University of Oxford as a researcher with Sir Hans Krebs. In 1973 he was made a f ...
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Kidlington
Kidlington is a major village and civil parish in Oxfordshire, England, between the River Cherwell and the Oxford Canal, north of Oxford and 7 miles (12 km) south-west of Bicester. It remains officially a village despite its size. The 2011 census put the parish population at 13,723. History Kidlington's toponym derives from the Old English ''Cudelinga tun'': the ''tun'' (settlement) of the "Kidlings" (sons) of Cydel-hence. The Domesday Book in 1086 records ''Chedelintone''. By 1214 the spelling ''Kedelinton'' appears in a Calendar of Bodleian Charters. The Church of England parish church of St Mary the Virgin dates from 1220, but there is evidence of a church on the site since 1073. St Mary's has fine medieval stained glass and a spire known as "Our Lady's Needle". It is a Grade I listed building. The tower has a ring of eight bells. Richard III Chandler of Drayton Parslow, Buckinghamshire, cast the seventh bell in 1700. Abraham I Rudhall of Gloucester cast the tenor ...
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Radcliffe Infirmary
The Radcliffe Infirmary was a hospital in central north Oxford, England, located at the southern end of Woodstock Road on the western side, backing onto Walton Street. History The initial proposals to build a hospital in Oxford were put forward at a meeting of the Radcliffe Trustees, who were administering John Radcliffe's estate valued at £4,000, in 1758. The facility was constructed on land given by Thomas Rowney, one of the two members of parliament for Oxford. The foundation stone was laid on 27 August 1761 and the new facility was officially opened on 18 October 1770. A fountain of the Greek god Triton was placed in front of the main infirmary building in 1858 and the Oxford Eye Hospital was established on the site in 1886.A brief history of the Nuffield Laboratory of Ophthalmology
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owi ...
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Nociception
Nociception (also nocioception, from Latin ''nocere'' 'to harm or hurt') is the Somatosensory system, sensory nervous system's process of encoding Noxious stimulus, noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal in order to trigger an appropriate defense response. In nociception, intense chemical (e.g., capsaicin present in Chili pepper or Cayenne pepper), mechanical (e.g., cutting, crushing), or thermal (heat and cold) stimulation of sensory neurons called nociceptors produces a signal that travels along a chain of nerve fibers via the spinal cord to the brain. Nociception triggers a variety of physiological and behavioral responses to protect the organism against an aggression and usually results in a subjective experience, or perception, of pain in Sentience, sentient beings. Detection of noxious stimuli Potentially damaging mecha ...
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British Neuroscience Association
The British Neuroscience Association (BNA) is a scientific society with around 2,500 members. Starting out as an informal gathering of scientists meeting at the Black Hourse Public House in London to discuss brain-related topics (the 'London Black Horse Group'), on the 23rd of February 1968 it was formerly established as the Brain Research Association, and subsequently relaunched as the British Neuroscience Association in 1997. The BNA is the largest UK organisation of its kind, supporting and promoting neuroscience and neuroscientists. Charitable objects It is a registered charity (number 1103852), with charitable objects as follows: ''‘To preserve and protect health and advance public education in neurosciences related to health and disease (in particular but not exclusively) by:’'' # ''Promoting on a multidisciplinary basis the study of the development structure and function of the nervous system in health and disease.'' # ''Promoting the dissemination of information ...
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