Iberogast
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Iberogast
Iberogast, also known as STW5, is a liquid formulation of nine herbs used for functional dyspepsia and irritable bowel syndrome. A proprietary blend, it was developed in Germany in 1961 and is available (without prescription) in other countries. Named after the genus (Iberis) of one of its ingredients, it is also claimed to possess anti-inflammatory, antioxidative and free radical-inhibiting properties as well as the ability to reduce gastric acid secretion. Iberogast is a mixture of extracts from bitter candytuft (''Iberis amara''), angelica root ('' Angelicae radix''), milk thistle fruit ('' Silybi mariani fructus''), celandine herb (''Chelidonium majus''), caraway fruit ('' Carvi fructus''), liquorice root ('' Liquiritiae radix''), peppermint herb ('' Menthae piperitae folium''), balm leaf ('' Melissae folium'') and chamomile flower ('' Matricariae flos''). Medical uses A 2004 meta-analysis comprising three randomized placebo-controlled studies with a total of 173 patients ...
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Chelidonium Majus
''Chelidonium majus'', the greater celandine, is a perennial herbaceous flowering plant in the poppy family Papaveraceae. One of two species in the genus ''Chelidonium'', it is native to Europe and western Asia and introduced widely in North America. The plant known as lesser celandine (''Ficaria verna'') is not closely related, as it belongs to the buttercup family Ranunculaceae. Description Greater celandine is a perennial herbaceous plant with an erect habit, and reaches high. The blue-green leaves are pinnate with lobed and wavy margins, up to long. When injured, the plant exudes a yellow to orange latex. The flowers consist of four yellow petals, each about long, with two sepals. A double-flowered variety occurs naturally. The flowers appear from late spring to summer, May to September (in the UK), in umbelliform cymes of about 4 flowers. The seeds are small and black, borne in a long, cylindrical capsule. Each has an elaiosome, which attracts ants to disperse the s ...
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Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a "disorder of gut-brain interaction" characterized by a group of symptoms that commonly include abdominal pain and or abdominal bloating and changes in the consistency of bowel movements. These symptoms may occur over a long time, sometimes for years. IBS can negatively affect quality of life and may result in missed school or work (absenteeism) or reduced productivity at work (presenteeism). Disorders such as anxiety, major depression, and chronic fatigue syndrome are common among people with IBS.The cited review is based on sources ranging from 1988 to 2001 and is probably biased relative to a more recent research. The causes of IBS may well be multi-factorial. Theories include combinations of "gut–brain axis" problems, alterations in gut motility, visceral hypersensitivity, infections including small intestinal bacterial overgrowth, neurotransmitters, genetic factors, and food sensitivity. Onset may be triggered by an intestinal infec ...
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Herb
In general use, herbs are a widely distributed and widespread group of plants, excluding vegetables and other plants consumed for macronutrients, with savory or aromatic properties that are used for flavoring and garnishing food, for medicinal purposes, or for fragrances. Culinary use typically distinguishes herbs from spices. ''Herbs'' generally refers to the leafy green or flowering parts of a plant (either fresh or dried), while ''spices'' are usually dried and produced from other parts of the plant, including seeds, bark, roots and fruits. Herbs have a variety of uses including culinary, medicinal, aromatic and in some cases, spiritual. General usage of the term "herb" differs between culinary herbs and medicinal herbs; in medicinal or spiritual use, any parts of the plant might be considered as "herbs", including leaves, roots, flowers, seeds, root bark, inner bark (and cambium), resin and pericarp. The word "herb" is pronounced in Commonwealth English, but is common am ...
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Peppermint
Peppermint (''Mentha'' × ''piperita'') is a hybrid species of mint, a cross between watermint and spearmint. Indigenous to Europe and the Middle East, the plant is now widely spread and cultivated in many regions of the world.Euro+Med Plantbase Project''Mentha'' × ''piperita''/ref> It is occasionally found in the wild with its parent species.Flora of NW Europe''Mentha'' × ''piperita'' Although the genus ''Mentha'' comprises more than 25 species, the one in most common use is peppermint. While Western peppermint is derived from ''Mentha × piperita'', Chinese peppermint, or ''bohe'', is derived from the fresh leaves of ''M. haplocalyx''. ''M. × piperita'' and ''M. haplocalyx'' are both recognized as plant sources of menthol and menthone, and are among the oldest herbs used for both culinary and medicinal products. Botany Peppermint was first described in 1753 by Carl Linnaeus from specimens that had been collected in England; he treated it as a species,Linnaeus, C. (17 ...
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Drugs Developed By Bayer
A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to treat, cure, prevent, or diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a regular basis for chronic disorders. Pharmaceutical drugs are often classified into drug classes—groups of related drugs ...
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Bayer
Bayer AG (, commonly pronounced ; ) is a German multinational corporation, multinational pharmaceutical and biotechnology company and one of the largest pharmaceutical companies in the world. Headquartered in Leverkusen, Bayer's areas of business include pharmaceuticals; consumer healthcare products, agricultural chemicals, seeds and biotechnology products. The company is a component of the Euro Stoxx 50 stock market index. Bayer was founded in 1863 in Barmen as a partnership between dye salesman Friedrich Bayer and dyer Friedrich Weskott. As was common in this era, the company was established as a dyestuffs producer. The versatility of aniline chemistry led Bayer to expand their business into other areas, and in 1899 Bayer launched the compound acetylsalicylic acid under the trademarked name Aspirin. In 1904 Bayer received a trademark for the "Bayer Cross" logo, which was subsequently stamped onto each aspirin tablet, creating an iconic product that is still sold by Bayer. Ot ...
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Gastroesophageal Reflux Disease
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is one of the upper gastrointestinal chronic diseases where stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. Symptoms include dental corrosion, dysphagia, heartburn, odynophagia, regurgitation, non-cardiac chest pain, extraesophageal symptoms such as chronic cough, hoarseness, reflux-induced laryngitis, or asthma. On the long term, and when not treated, complications such as esophagitis, esophageal stricture, and Barrett's esophagus may arise. Risk factors include obesity, pregnancy, smoking, hiatal hernia, and taking certain medications. Medications that may cause or worsen the disease include benzodiazepines, calcium channel blockers, tricyclic antidepressants, NSAIDs, and certain asthma medicines. Acid reflux is due to poor closure of the lower esophageal sphincter, which is at the junction between the stomach and the esoph ...
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Case–control Study
A case–control study (also known as case–referent study) is a type of observational study in which two existing groups differing in outcome are identified and compared on the basis of some supposed causal attribute. Case–control studies are often used to identify factors that may contribute to a medical condition by comparing subjects who have that condition/disease (the "cases") with patients who do not have the condition/disease but are otherwise similar (the "controls"). They require fewer resources but provide less evidence for causal inference than a randomized controlled trial. A case–control study produces only an odds ratio, which is an inferior measure of strength of association compared to relative risk. Definition The case–control is a type of epidemiological observational study. An observational study is a study in which subjects are not randomized to the exposed or unexposed groups, rather the subjects are ''observed'' in order to determine both their expos ...
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Meta-analysis
A meta-analysis is a statistical analysis that combines the results of multiple scientific studies. Meta-analyses can be performed when there are multiple scientific studies addressing the same question, with each individual study reporting measurements that are expected to have some degree of error. The aim then is to use approaches from statistics to derive a pooled estimate closest to the unknown common truth based on how this error is perceived. Meta-analytic results are considered the most trustworthy source of evidence by the evidence-based medicine literature.Herrera Ortiz AF., Cadavid Camacho E, Cubillos Rojas J, Cadavid Camacho T, Zoe Guevara S, Tatiana Rincón Cuenca N, Vásquez Perdomo A, Del Castillo Herazo V, & Giraldo Malo R. A Practical Guide to Perform a Systematic Literature Review and Meta-analysis. Principles and Practice of Clinical Research. 2022;7(4):47–57. https://doi.org/10.21801/ppcrj.2021.74.6 Not only can meta-analyses provide an estimate of the un ...
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Matricaria Chamomilla
''Matricaria chamomilla'' (synonym: ''Matricaria recutita''), commonly known as chamomile (also spelled camomile), German chamomile, Hungarian chamomile (kamilla), wild chamomile, blue chamomile, or scented mayweed, is an annual plant of the composite family Asteraceae. Commonly, the name ''M. recutita'' is applied to the most popular source of the herbal product chamomile, although other species are also used as chamomile. Chamomile is known mostly for its use against gastrointestinal problems; additionally, it can be used to treat irritation of the skin. Description ''Matricaria chamomilla'' is a member of the Asteraceae family, native to southern and eastern Europe. Today the plant can be found on all continents. It has a branched, erect and smooth stem, which grows to a height of . The long and narrow leaves are bipinnate or tripinnate. The flowers are borne in paniculate flower heads (capitula). The white ray florets are furnished with a ligule, while the disc florets ...
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Melissa (plant)
''Melissa'' is a genus of perennial herbs in the Lamiaceae, native to Europe and Asia but cultivated and naturalized in many other places. The name ''Melissa'' is derived from the Greek word (''mélissa'') meaning "honeybee", owing to the abundance of nectar in the flowers. The stems are square, like most other plants in the mint family. The leaves are borne in opposite pairs on the stems, and are usually ovate or heart-shaped and emit a lemony scent when bruised. Axillary spikes of white or yellowish flowers appear in the summer. The most commonly grown species of this genus is ''Melissa officinalis'', commonly known in the United States as lemon balm, and as balm in England. Species # ''Melissa axillaris'' (Benth.) Bakh.f. - China (incl. Tibet + Taiwan), Himalayas, Indochina, Sumatra, Java # ''Melissa flava'' Benth. ex Wall. - Tibet, Nepal, Bhutan, Himalayas of northern + Eastern India # ''Melissa officinalis'' L. - Mediterranean, southwestern + central Asia from Portugal ...
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Caraway
Caraway, also known as meridian fennel and Persian cumin (''Carum carvi''), is a biennial plant in the family Apiaceae, native to western Asia, Europe, and North Africa. Etymology The etymology of "caraway" is unclear. Caraway has been called by many names in different regions, with names deriving from the Latin ''cuminum'' ( cumin), the Greek ''karon'' (again, cumin), which was adapted into Latin as ''carum'' (now meaning caraway), and the Sanskrit ''karavi'', sometimes translated as "caraway", but other times understood to mean "fennel".Katzer's Spice PagesCaraway Caraway (''Carum carvi'' L.)/ref> English use of the term caraway dates to at least 1440, possibly having Arabic origin.Walter William Skeat, Principles of English Etymology, Volume 2, page 319. 189Words of Arabic Origin/ref> Description The plant is similar in appearance to other members of the carrot family, with finely divided, feathery leaves with thread-like divisions, growing on stems. The main flow ...
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