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INAH 3
INAH-3 is the short form for the third interstitial nucleus of the anterior hypothalamus, and is the sexually dimorphic nucleus of humans. The INAH-3 is significantly larger in males than in females regardless of age and larger in heterosexual males than in homosexual males and heterosexual females. Research The term INAH (interstitial nuclei of the anterior hypothalamus), first proposed in 1989 by a group of the University of California at Los Angeles, refers to 4 previously undescribed cell groups of the preoptic-anterior hypothalamic area (PO-AHA) of the human brain, which is a structure that influences gonadotropin secretion, maternal behavior, and sexual behavior in several mammalian species. There are four nuclei in the PO-AHA (INAH1-4). One of these nuclei, INAH-3, was found to be 2.8 times larger in the male brain than in the female brain regardless of age. A study authored by Simon LeVay and published in the journal ''Science'' suggests that the region is an important b ...
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Interstitial
An interstitial space or interstice is a space between structures or objects. In particular, interstitial may refer to: Biology * Interstitial cell tumor * Interstitial cell, any cell that lies between other cells * Interstitial collagenase, enzyme that breaks the peptide bonds in collagen * Interstitial cystitis * Interstitium, the contiguous fluid-filled space existing between the skin and body organs * Interstitial fluid, a solution that bathes and surrounds the cells of multicellular animals * Interstitial granulomatous dermatitis * Interstitial infusion * Interstitial keratitis * Interstitial lung disease * Interstitial nephritis * Interstitial pregnancy Other uses To describe the spaces within particulate matter such sands, gravels, cobbles, grain, etc. that lie between the discrete particles. * Interstitial art * Interstitial condensation, in construction * Interstitial site, in chemistry * Interstitial defect, in chemistry * Interstitial television show ...
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Sexual Orientation
Sexual orientation is an enduring pattern of romantic or sexual attraction (or a combination of these) to persons of the opposite sex or gender, the same sex or gender, or to both sexes or more than one gender. These attractions are generally subsumed under heterosexuality, homosexuality, and bisexuality, while asexuality (the lack of sexual attraction to others) is sometimes identified as the fourth category. These categories are aspects of the more nuanced nature of sexual identity and terminology. For example, people may use other labels, such as '' pansexual'' or '' polysexual'', or none at all. According to the American Psychological Association, sexual orientation "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions". ''Androphilia'' and ''gynephilia'' are terms used in behavioral science to describe sexual orientation as an alternative to a gender binary conc ...
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Dick Swaab
Dick Ferdinand Swaab (born 17 December 1944) is a Dutch physician and neurobiologist (brain researcher). He is a professor of neurobiology at the University of Amsterdam and was until 2005 Director of the Netherlands Institute for Brain Research (Nederlands Instituut voor Hersenonderzoek) of the Royal Netherlands Academy of Arts and Sciences (Koninklijke Nederlandse Akademie van Wetenschappen). Life Swaab graduated at the Amsterdams Lyceum in 1963. He received his doctorate of medicine at the University of Amsterdam in 1968, and his Ph.D. in 1970 with professor J. Ariëns Kappers on a neuroendocrine thesis, and in 1972 he received his medical degree. He was from 1978 the director of the Netherlands Institute for Brain Research. In 1979 he was appointed professor of neurobiology at the University of Amsterdam. In 1985 he founded the Nederlandse Hersenbank—known in English as The Netherlands Brain Bank—to facilitate international research on brain diseases. Swaab is an atheist ...
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Transgender
A transgender (often abbreviated as trans) person is someone whose gender identity or gender expression does not correspond with their sex assigned at birth. Many transgender people experience dysphoria, which they seek to alleviate through transitioning, often adopting a different name and set of pronouns in the process. Additionally, they may undergo sex reassignment therapies such as hormone therapy and sex reassignment surgery to more closely align their primary and secondary sex characteristics with their gender identity. Not all transgender people desire these treatments, however, and others may be unable to access them for financial or medical reasons. Those who do desire to medically transition to another sex may identify as transsexual. ''Transgender'' is an umbrella term. In addition to trans men and trans women, it may also include people who are non-binary or genderqueer. Other definitions of ''transgender'' also include people who belong to a third gender, ...
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Confounding Variable
In statistics, a confounder (also confounding variable, confounding factor, extraneous determinant or lurking variable) is a variable that influences both the dependent variable and independent variable, causing a spurious association. Confounding is a causal concept, and as such, cannot be described in terms of correlations or associations.Pearl, J., (2009). Simpson's Paradox, Confounding, and Collapsibility In ''Causality: Models, Reasoning and Inference'' (2nd ed.). New York : Cambridge University Press. The existence of confounders is an important quantitative explanation why correlation does not imply causation. Confounds are threats to internal validity. Definition Confounding is defined in terms of the data generating model. Let ''X'' be some independent variable, and ''Y'' some dependent variable. To estimate the effect of ''X'' on ''Y'', the statistician must suppress the effects of extraneous variables that influence both ''X'' and ''Y''. We say that ''X'' and ...
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Neuron
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body ( soma), dendrites, and a single axon. The soma is a compact structure, and the axo ...
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Heterosexual
Heterosexuality is romantic attraction, sexual attraction or sexual behavior between people of the opposite sex or gender. As a sexual orientation, heterosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to people of the opposite sex; it "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions." Someone who is heterosexual is commonly referred to as ''straight.'' Along with bisexuality and homosexuality, heterosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Across cultures, most people are heterosexual, and heterosexual activity is by far the most common type of sexual activity. Scientists do not know the exact cause of sexual orientation, but they theorize that it is caused by a complex interplay of genetic, hormonal, and environmental influences, and do not view it as ...
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Homosexual
Homosexuality is romantic attraction, sexual attraction, or sexual behavior between members of the same sex or gender. As a sexual orientation, homosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to people of the same sex. It "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions." Along with bisexuality and heterosexuality, homosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Scientists do not yet know the exact cause of sexual orientation, but they theorize that it is caused by a complex interplay of genetic, hormonal, and environmental influences and do not view it as a choice. Although no single theory on the cause of sexual orientation has yet gained widespread support, scientists favor biologically based theories. There is considerably more evidence support ...
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Neural Substrate
A neural substrate is a term used in neuroscience to indicate the part of the central nervous system (i.e., brain and spinal cord) that underlies a specific behavior, cognitive process, or psychological state. ''Neural'' is an adjective relating to "a nerve or the nervous system", while a ''substrate'' is an "underlying substance or layer". Some examples are the neural substrates of language acquisition, memory, prediction and reward, pleasure Pleasure refers to experience that feels good, that involves the enjoyment of something. It contrasts with pain or suffering, which are forms of feeling bad. It is closely related to value, desire and action: humans and other conscious animals ..., facial recognition, envisioning the future, intentional empathy, religious experience, spontaneous musical performance, and anxiety. See also * Neural correlate References Neuroscience {{neuroscience-stub ...
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Nucleus (neuroanatomy)
In neuroanatomy, a nucleus (plural form: nuclei) is a cluster of neurons in the central nervous system, located deep within the cerebral hemispheres and brainstem. The neurons in one nucleus usually have roughly similar connections and functions. Nuclei are connected to other nuclei by tracts, the bundles (fascicles) of axons (nerve fibers) extending from the cell bodies. A nucleus is one of the two most common forms of nerve cell organization, the other being layered structures such as the cerebral cortex or cerebellar cortex. In anatomical sections, a nucleus shows up as a region of gray matter, often bordered by white matter. The vertebrate brain contains hundreds of distinguishable nuclei, varying widely in shape and size. A nucleus may itself have a complex internal structure, with multiple types of neurons arranged in clumps (subnuclei) or layers. The term "nucleus" is in some cases used rather loosely, to mean simply an identifiably distinct group of neurons, even if they ...
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Science (journal)
''Science'', also widely referred to as ''Science Magazine'', is the peer-reviewed academic journal of the American Association for the Advancement of Science (AAAS) and one of the world's top academic journals. It was first published in 1880, is currently circulated weekly and has a subscriber base of around 130,000. Because institutional subscriptions and online access serve a larger audience, its estimated readership is over 400,000 people. ''Science'' is based in Washington, D.C., United States, with a second office in Cambridge, UK. Contents The major focus of the journal is publishing important original scientific research and research reviews, but ''Science'' also publishes science-related news, opinions on science policy and other matters of interest to scientists and others who are concerned with the wide implications of science and technology. Unlike most scientific journals, which focus on a specific field, ''Science'' and its rival ''Nature'' cover the full r ...
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Simon LeVay
Simon LeVay (born 28 August 1943 in Oxford, England) is a British-American neuroscientist. He received a bachelor's degree in natural sciences from the University of Cambridge in 1966, a Ph.D. in Neuroanatomy at the University of Göttingen in Germany, and completed his post doctoral fellowship at Harvard Medical School in 1974. LeVay held positions in neurobiology at the Harvard Medical School from 1974 to 1984. He then worked at the Salk Institute for Biological Studies from 1984 to 1993 while holding an Associate Professorship in Biology at the University of California, San Diego. Much of his early work focused on the visual cortex in animals. While working at the Salk Institute for Biological Studies, LeVay published an article in Science that compared the size of the "Interstitial Nucleus of the Anterior Hypothalamus" ( INAH3) in a group of gay men to a group of straight men and women. This was the first scientific study ever published that showed brain differences based ...
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