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Instituto Gulbenkian De Ciência
The Instituto Gulbenkian de Ciência (IGC) was an international centre for biological and biomedical research and graduate training based in Oeiras, Portugal. Founded by the Calouste Gulbenkian Foundation (FCG) in 1961, and was supported by the Foundation until it merged with Instituto de Medicina Molecular to become Gulbenkian Institute of Molecular Medicine on October 1st 2024. The IGC was organised in small independent research groups that work in an environment designed to encourage interactions with minimal hierarchical structure. The scientific programme covered a wide range of domains and was at the interface of different disciplines. These included cell and developmental biology, evolutionary biology, immunology and host-pathogen interaction, plant biology, sociobiology, computational biology and biophysics. All resources were at the disposal of all IGC scientists equally, and common services and equipment were also open to external users. The IGC hosted a number of gr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oeiras Municipality, Portugal
Oeiras () is a town and municipality in the western part of Lisbon metropolitan area, located within the Portuguese Riviera, in continental Portugal. The municipality is part of the urban agglomeration of Lisbon and the town of Oeiras is about 16 km from Lisbon downtown. The population in 2011 was 172,120 living in an area of 45.88 km2, making the municipality the fifth-most densely populated in Portugal. Oeiras is an important economic hub, being one of the most highly developed municipalities of Portugal and Europe. It has the highest GDP per capita in the country, being also the second highest-ranking municipality (immediately after Lisbon) in terms of purchasing power as well as the second highest-ranking in the country as far as tax collection is concerned. These economic indicators also reflect the education level of its inhabitants, as Oeiras is the municipality with the highest concentration of population by tertiary education attainment in the country, their e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
António Coutinho
António Manuel Pinto Amaral Coutinho (born 8 October 1946, Aveiro, Portugal) is a Portuguese immunologist.He got his MD from Lisbon University Medical School in 1969, and his PhD in Medical Microbiology (supervisor Göran Möller) from the Karolinska Institute (Stockholm) in 1974, where he gained the Associate Professor title (1974). In 1975, he joined the Basel Institute of Immunology, directed by Niels K. Jerne, where he stayed until 1979. In 1978, he was appointed "special investigator" at the Swedish Medical Research Council, and in 1979, Professor of Immunology and Director of the Immunology Department in the Medical School at the University of Umea (Sweden). In 1980, he was appointed Research Director at the CNRS (France), and in 1982 he moved to the Pasteur Institute, where he was made Professor and created and directed the research Unit of Immunobiology, at the Department of Immunology. Antonio Coutinho stayed at the Pasteur Institute until 1998; meanwhile he was appoin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrophage
Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. This self-protection method can be contrasted with that employed by Natural killer cell, Natural Killer cells. This process of engulfment and digestion is called phagocytosis; it acts to defend the host against infection and injury. Macrophages are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adapti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature Medicine
''Nature Medicine'' is a monthly peer-reviewed medical journal published by Nature Portfolio covering all aspects of medicine. It was established in 1995. The journal seeks to publish research papers that "demonstrate novel insight into disease processes, with direct evidence of the physiological relevance of the results". As with other ''Nature'' journals, there is no external editorial board, with editorial decisions being made by an in-house team, although peer review by external expert referees forms a part of the review process. The editor-in-chief is João Monteiro. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor of 58.7, ranking it 1st out of 296 journals in the category "Biochemistry & Molecular Biology". The table below provides a detailed overview of recent bibliometric indicators for ''Nature Medicine'': Abstracting and indexing ''Nature Medicine'' is abstracted and indexed in: * Science Citation Index Expanded * Web of Scie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ana Domingos
Ana I. Domingos is a Portuguese neuroscientist specialising in the treatment of obesity independently of food intake. Domingos is a full Professor of Neuroscience at the Department of Physiology, Anatomy and Genetics of the University of Oxford in the United Kingdom. Domingos is also a fellow, tutor and the director of studies in medicine at Lady Margaret Hall, Oxford. A trained mathematician, Domingos began her research career by pursuing a Ph.D in neurobiology at Rockefeller University. Supervised by Leslie B. Vosshall, Leslie Voshall, Domingos studied the sensory systems facilitating our sense of smell. As a post-doctoral research scientist, Domingos worked under Jeffrey M. Friedman, Jeffrey Friedman, investigating how ones metabolism can influence the brain circuitry involved in sweetener cravings. Domingos founded her own laboratory in thGulbenkian Institutein Portugal where she made a number of key discoveries. Firstly, her laboratory discovered that a hormone produced by f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific Reports
''Scientific Reports'' is a peer-reviewed open-access scientific mega journal published by Nature Portfolio, covering all areas of the natural sciences. The journal was established in 2011. The journal states that their aim is to assess solely the scientific validity of a submitted paper, rather than its perceived importance, significance, or impact. In September 2016, the journal became the largest in the world by number of articles, overtaking '' PLOS ONE''. Abstracting and indexing The journal is abstracted and indexed in the Chemical Abstracts Service, the Science Citation Index Expanded, and selectively in Index Medicus/MEDLINE/PubMed. According to the ''Journal Citation Reports'', the journal has a 2023 impact factor 3.8. Reviewing policy The ''Guide to Referees'' states that to be published, "a paper must be scientifically valid and technically sound in methodology and analysis", and reviewers have to ensure manuscripts "are not assessed based on their perceived impor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Google Trends
Google Trends is a website by Google that analyzes the popularity of top search queries in Google Search across various regions and languages. The website uses graphs to compare the search volume of different queries over a certain period of time. On August 5, 2008, Google launched Google Insights for Search, a more sophisticated and advanced service displaying search trends data. On September 27, 2012, Google merged Google Insights for Search into Google Trends. History 2000s Originally, Google neglected updating Google Trends on a regular basis. In March 2007, internet bloggers noticed that Google had not added new data since November 2006, and Trends was updated within a week. Google did not update Trends from March until July 30, and only after it was blogged about, again. Google now claims to be "updating the information provided by Google Trends daily; Hot Trends is updated hourly." As of April 2025, data on the Google Trends website shows updates every minute, with a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Twitter
Twitter, officially known as X since 2023, is an American microblogging and social networking service. It is one of the world's largest social media platforms and one of the most-visited websites. Users can share short text messages, images, and videos in Microblogging, short posts commonly known as "Tweet (social media), tweets" (officially "posts") and Like button, like other users' content. The platform also includes direct message, direct messaging, video and audio calling, bookmarks, lists, communities, a chatbot (Grok (chatbot), Grok), job search, and Spaces, a social audio feature. Users can vote on context added by approved users using the Community Notes feature. Twitter was created in March 2006 by Jack Dorsey, Noah Glass, Biz Stone, and Evan Williams (Internet entrepreneur), Evan Williams, and was launched in July of that year. Twitter grew quickly; by 2012 more than 100 million users produced 340 million daily tweets. Twitter, Inc., was based in San Francisco, C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cilium
The cilium (: cilia; ; in Medieval Latin and in anatomy, ''cilium'') is a short hair-like membrane protrusion from many types of eukaryotic cell. (Cilia are absent in bacteria and archaea.) The cilium has the shape of a slender threadlike projection that extends from the surface of the much larger cell body. Eukaryotic flagella found on sperm cells and many protozoans have a similar structure to motile cilia that enables swimming through liquids; they are longer than cilia and have a different undulating motion. There are two major classes of cilia: ''motile'' and ''non-motile'' cilia, each with two subtypes, giving four types in all. A cell will typically have one primary cilium or many motile cilia. The structure of the cilium core, called the axoneme, determines the cilium class. Most motile cilia have a central pair of single microtubules surrounded by nine pairs of double microtubules called a 9+2 axoneme. Most non-motile cilia have a 9+0 axoneme that lacks the centr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ciliopathy
Ciliopathies are a group of genetically diverse disorders caused by defects in the structure or function of the primary cilium, a highly specialized and evolutionarily conserved organelle found in nearly all eukaryotic cells. The primary cilium plays a central role in regulating signal transduction and making it essential for numerous developmental and physiological processes. Because of the widespread presence of primary cilia in different tissues, dysfunction can lead to a broad spectrum of clinical features. Syndromic ciliopathies, such as Bardet-Biedl syndrome (BBS), typically involve multiple organ systems, including the retina, kidneys, central nervous system, and skeletal system These manifestations highlight the importance of cilia in embryonic development, sensory perception, and tissue homeostasis. The genetic basis of ciliopathies is complex, with significant allelic heterogeneity and pleiotropy, meaning the same gene may cause different disorders, while diff ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature Cell Biology
''Nature Cell Biology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. It was established in 1999. The founding editor was Annette Thomas. The current editor-in-chief is Christina Kary. According to the Nature Cell Biology, the journal has a 2023 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 26.6. References External links * Academic journals established in 1999 Nature Research academic journals Monthly journals Molecular and cellular biology journals {{molec-cell-biology-journal-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Cologne
The University of Cologne () is a university in Cologne, Germany. It was established in 1388. It closed in 1798 before being re-established in 1919. It is now one of the largest universities in Germany with around 45,187 students. The University of Cologne is a member of the U15 (German universities), German U15 association of major research-intensive universities and was a university of excellence as part of the German Universities Excellence Initiative from 2012 to 2019. It is constantly ranked among top 20 German universities in the world rankings. The University of Cologne has 5 Clusters of Excellence: CECAD Cluster of Excellence for Aging Research, Cluster of Excellence ECONtribute: Markets & Public Policy, CEPLAS Cluster of Excellence for Plant Sciences, ML4Q Cluster of Excellence Matter and Light for Quantum Information and DYNAVERSE Cluster of Excellence. As of 2025, among its notable alumni, faculty and researchers are 5 List of Nobel laureates, Nobel Laureates, 11 Le ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
