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Huntingdon Life Sciences
Huntingdon Life Sciences (HLS) was a contract research organisation (CRO) founded in 1951 in Cambridgeshire, England. It had two laboratories in the United Kingdom and one in the United States. With over 1,600 staff, it was until 2015 the largest non-clinical CRO in Europe. In September 2015, Huntingdon Life Sciences, Harlan Laboratories, GFA, NDA Analytics and LSR associates merged into Envigo, which later sold off the CRO part. In 2009, HLS was bought outright and is now in private ownership. Prior to this, the latest annual report (2008) showed that the company had revenues of $US242.4m and an operating profit of 14.8%. Although HLS is the third-largest non-clinical CRO in the world, it is probably better known to the general public as the target of a high-profile animal rights campaign. The campaign, in the main, has been orchestrated by the animal rights group Stop Huntingdon Animal Cruelty (SHAC). Locations HLS has two facilities in the UK (Huntingdon, Cambridgeshire and ...
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Brian Cass
Brian Cass is the managing director of Huntingdon Life Sciences, a contract research organisation company based in Huntingdon in the United Kingdom and New Jersey in the United States. Before moving to Huntingdon Life Sciences, Cass was the managing director of Covance Laboratories Ltd. He was appointed a CBE in 2002.Animal test chief's CBE 'is for firm'
''Telegraph''; accessed 23 February 2014.


Career

He was appointed to the Board of Huntingdon as Managing Director/Chief Operating Officer in 1998. He became a Director and Managing Director/President of LSR Inc in 2002.Huntingdon Life Sciences Annual Report 2000, p. 67 He has held directorships with North Yorkshire Training & Enterprise Council Ltd and Business ...
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New York Stock Exchange
The New York Stock Exchange (NYSE, nicknamed "The Big Board") is an American stock exchange in the Financial District of Lower Manhattan in New York City. It is by far the world's largest stock exchange by market capitalization of its listed companies at US$30.1 trillion as of February 2018. The average daily trading value was approximately 169 billion in 2013. The NYSE trading floor is at the New York Stock Exchange Building on 11 Wall Street and 18 Broad Street and is a National Historic Landmark. An additional trading room, at 30 Broad Street, was closed in February 2007. The NYSE is owned by Intercontinental Exchange, an American holding company that it also lists (). Previously, it was part of NYSE Euronext (NYX), which was formed by the NYSE's 2007 merger with Euronext. History The earliest recorded organization of securities trading in New York among brokers directly dealing with each other can be traced to the Buttonwood Agreement. Previously, sec ...
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Mammals
Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or hair, and three middle ear bones. These characteristics distinguish them from reptiles (including birds) from which they diverged in the Carboniferous, over 300 million years ago. Around 6,400 extant species of mammals have been described divided into 29 orders. The largest orders, in terms of number of species, are the rodents, bats, and Eulipotyphla ( hedgehogs, moles, shrews, and others). The next three are the Primates (including humans, apes, monkeys, and others), the Artiodactyla (cetaceans and even-toed ungulates), and the Carnivora ( cats, dogs, seals, and others). In terms of cladistics, which reflects evolutionary history, mammals are the only living members of the Synapsida (synapsids); this clade, together with S ...
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Bird
Birds are a group of warm-blooded vertebrates constituting the class Aves (), characterised by feathers, toothless beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart, and a strong yet lightweight skeleton. Birds live worldwide and range in size from the bee hummingbird to the ostrich. There are about ten thousand living species, more than half of which are passerine, or "perching" birds. Birds have whose development varies according to species; the only known groups without wings are the extinct moa and elephant birds. Wings, which are modified forelimbs, gave birds the ability to fly, although further evolution has led to the loss of flight in some birds, including ratites, penguins, and diverse endemic island species. The digestive and respiratory systems of birds are also uniquely adapted for flight. Some bird species of aquatic environments, particularly seabirds and some waterbirds, have further evolved for swim ...
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Fish
Fish are aquatic, craniate, gill-bearing animals that lack limbs with digits. Included in this definition are the living hagfish, lampreys, and cartilaginous and bony fish as well as various extinct related groups. Approximately 95% of living fish species are ray-finned fish, belonging to the class Actinopterygii, with around 99% of those being teleosts. The earliest organisms that can be classified as fish were soft-bodied chordates that first appeared during the Cambrian period. Although they lacked a true spine, they possessed notochords which allowed them to be more agile than their invertebrate counterparts. Fish would continue to evolve through the Paleozoic era, diversifying into a wide variety of forms. Many fish of the Paleozoic developed external armor that protected them from predators. The first fish with jaws appeared in the Silurian period, after which many (such as sharks) became formidable marine predators rather than just the prey of arthropods. ...
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Mouse
A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not taxonomically specific. Typical mice are classified in the genus ''Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, ''Peromyscus''. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding a ...
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Understanding Animal Research
Understanding Animal Research (UAR) is a British membership organisation formed in late 2008 through the merger of the Research Defence Society and the Coalition for Medical Progress. Its main aims are to "explain why animals are used in medical and scientific research. We aim to achieve a broad understanding of the humane use of animals in medical, veterinary, scientific and environmental research in the UK". History The Research Defence Society (RDS) was founded in 1908 "to make known the facts as to experiments on animals in this country; the immense importance to the welfare of mankind of such experiments and the great saving of human life and health directly attributable to them". Within a year, the society had over 2000 members with branches across the country organising lectures and debates. Over the next century the RDS campaigned against animal rights extremism including lobbying for a strengthened version of the Criminal Justice and Public Order Bill in 1994 and settin ...
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Fund For The Replacement Of Animals In Medical Experiments
Fund for the Replacement of Animals in Medical Experiments (FRAME) is a charity based in Nottingham, UK. FRAME promotes consideration of the ethical and scientific issues involved in the use of laboratory animals for medical research, and the adoption of the Three Rs strategy of alternatives to animal testing. The Three Rs The Three Rs (Replacement, Reduction, Refinement) strategy was first suggested by zoologist William Russell and microbiologist Rex Burch, with Replacement being the ultimate goal. FRAME campaigns for the replacement of animal testing methods with alternatives that do not use animals. If there is no valid alternative, FRAME believes the number of animals involved should be reduced as far as possible, and the procedures applied should be refined to minimise potential pain and distress. The FRAME research programme involves both office-based and laboratory-based research. Staff at the Nottingham city offices and the FRAME Alternatives Laboratory at The Univ ...
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Association For Assessment And Accreditation Of Laboratory Animal Care
The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Laboratory Animal Care, or AAALAC. In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). The name change reflects the organization's growth in other countries, and its commitment to enhancing life sciences and quality animal care around the world. Today, more than 900 organizations worldwide are accredited. Along with meeting all applicable local and national regulations, AAALAC accredited institutions must also demonstrate that they are achieving the standards outlined in the Guide for the Care and Use of Laborator ...
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Association Of The British Pharmaceutical Industry
The Association of the British Pharmaceutical Industry (ABPI) is the trade association for over 120 companies in the UK producing prescription medicines for humans, founded in 1891.Healthcare Distribution Association: Our History
HDA UK (Accessed Jan 2020)
It is the British equivalent of America's PhRMA; however, the member companies research, develop, manufacture and supply 80% of the medicines prescribed through the

Crop Protection
Crop protection is the science and practice of managing plant diseases, weeds, and other pests (both vertebrate and invertebrate) that damage crops and forestry. Crops include field crops (maize, wheat, rice, etc.), vegetable crops ( potatoes, cabbages, etc.), and fruits. The crops in the field are exposed to many factors. The crop plants may be damaged by insects, birds, rodents, bacteria, etc. Crop protection encompasses: *All practical aspects of pest, disease, and weed control, including the following topics: *Control of animal pests of world crops. *Control of diseases of crop plants caused by microorganisms. *Control of weeds and integrated management. * Economic considerations. See also * CAB International * CropLife International * Integrated pest management * Vive Crop Protection Vive Crop Protection is a privately held company based in Toronto, Canada, that develops new products based on existing active ingredients for pesticides using its patented Allosperse techno ...
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Contract Research Organization
In the life sciences, a contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. A CRO may provide such services as biopharmaceutical development, biological assay development, commercialization, clinical development, clinical trials management, pharmacovigilance, outcomes research, and Real world evidence. CROs are designed to reduce costs for companies developing new medicines and drugs in niche markets. They aim to simplify entry into drug markets, and simplify development, as the need for large pharmaceutical companies to do everything ‘in house’ is now redundant. CROs also support foundations, research institutions, and universities, in addition to governmental organizations (such as the NIH, EMA, etc.). Many CROs specifically provide clinical-study and clinical-trial support for drugs and/or medical devices. However ...
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