Honor Smith
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Honor Smith
Honor Mildred Vivian Smith (13 November 1908 – 18 January 1995) was an English neurologist who specialised in the treatment of tuberculous meningitis. She worked and taught at the teaching hospitals of the University of Oxford, and was appointed OBE in 1962. Early life and education Honor Smith was born in Chigwell, Essex. She was the sixth of seven children born to Vivian Smith, 1st Baron Bicester, and Lady Sybil Mary McDonnell, the daughter of William Randal McDonnell, 6th Earl of Antrim. She had a passion for hunting, inspired by her father, but she decided to pursue a career in medicine, influenced by her mother, instead of becoming master of hounds for the Bicester hunt. She enrolled at the London School of Medicine for Women, where her mother's friend Lady Florence Barrett was dean. She received a BSc in 1937 and graduated from the Royal Free Hospital School of Medicine as MBBS in 1941. Career Smith began her medical career at the Elizabeth Garrett Anderson Hospital i ...
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Chigwell
Chigwell is a town and civil parish in the Epping Forest District of Essex, England. It is part of the urban and metropolitan area of London, and is adjacent to the northern boundary of Greater London. It is on the Central line of the London Underground. History Toponymy According to P. H. Reaney's ''Place-Names of Essex'' the name means 'Cicca's well', Cicca being an Anglo-Saxon personal name. In medieval sources the name appears with a variety of spellings including "Cinghe uuella" and Chikewelle". Folk etymology has sought to derive the name from a lost "king's well", supposed to have been to the south-east of the parish near the border of what is now the London Borough of Redbridge. There were several medicinal springs in Chigwell Row documented by Miller Christy in his book ''History of the mineral waters and medicinal springs of the county of Essex'', published in 1910. The 18th-century historian Nathaniel Salmon stated that the "-well" element in the name derives from A ...
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Oxford
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to dom ...
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Churchill Hospital
The Churchill Hospital is a teaching hospital in Oxford, England. It is managed by the Oxford University Hospitals NHS Foundation Trust. History The original hospital on the site was built in 1940 with the intention of providing medical aid to people suffering orthopaedic injuries as a result of air raids during the Second World War. This proved unnecessary, and the building was leased to the United States Army medical services, who were relocating from Basingstoke. The new American hospital was named after Sir Winston Churchill, the then Prime Minister, and was opened by the Duchess of Kent on 27 January 1942. The US Army left the hospital at the end of the war and it was taken over by the local council and reopened as a conventional hospital in January 1946. The Churchill Hospital came under common management with the John Radcliffe Hospital in April 1993 and with the Nuffield Orthopaedic Centre in November 2011. New cancer treatment facilities were procured under a Private Fi ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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Rockefeller Foundation
The Rockefeller Foundation is an American private foundation and philanthropic medical research and arts funding organization based at 420 Fifth Avenue, New York City. The second-oldest major philanthropic institution in America, after the Carnegie Corporation, the foundation was ranked as the 39th largest U.S. foundation by total giving as of 2015. By the end of 2016, assets were tallied at $4.1 billion (unchanged from 2015), with annual grants of $173 million. According to the OECD, the foundation provided US$103.8 million for development in 2019. The foundation has given more than $14 billion in current dollars. The foundation was started by Standard Oil magnate John D. Rockefeller ("Senior") and son "Junior", and their primary business advisor, Frederick Taylor Gates, on May 14, 1913, when its charter was granted by New York. The foundation has had an international reach since the 1930s and major influence on global non-governmental organizations. The World Health Organiza ...
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Boston Children's Hospital
Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical School, and to Dana–Farber Cancer Institute. Dana–Farber and Children's jointly operate the Dana–Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital-based pediatric research program in the world. The hospital features 485 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants, children, teens, and young adults aged 0–21 throughout Massachusetts, the United States, and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center, one of t ...
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Pneumococcal Meningitis
A pneumococcal infection is an infection caused by the bacterium ''Streptococcus pneumoniae'', which is also called the pneumococcus. ''S. pneumoniae'' is a common member of the bacterial flora colonizing the nose and throat of 5–10% of healthy adults and 20–40% of healthy children. However, it is also a cause of significant disease, being a leading cause of pneumonia, bacterial meningitis, and sepsis. The World Health Organization estimates that in 2005 pneumococcal infections were responsible for the death of 1.6 million children worldwide. Infections Pneumococcal pneumonia represents 15%–50% of all episodes of community-acquired pneumonia, 30–50% of all cases of acute otitis media, and a significant proportion of bloodstream infections and bacterial meningitis.Verma R, Khanna P (2012) Pneumococcal conjugate vaccine: A newer vaccine available in India. Hum Vaccin Immunother 8(9) As estimated by WHO in 2005 it killed about 1.6 million children every year worldwide with ...
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Penicillin
Penicillins (P, PCN or PEN) are a group of β-lactam antibiotics originally obtained from ''Penicillium'' moulds, principally '' P. chrysogenum'' and '' P. rubens''. Most penicillins in clinical use are synthesised by P. chrysogenum using deep tank fermentation and then purified. A number of natural penicillins have been discovered, but only two purified compounds are in clinical use: penicillin G (intramuscular or intravenous use) and penicillin V (given by mouth). Penicillins were among the first medications to be effective against many bacterial infections caused by staphylococci and streptococci. They are still widely used today for different bacterial infections, though many types of bacteria have developed resistance following extensive use. 10% of the population claims penicillin allergies but because the frequency of positive skin test results decreases by 10% with each year of avoidance, 90% of these patients can tolerate penicillin. Additionally, those with ...
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Intrathecal
Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches the cerebrospinal fluid (CSF) and is useful in spinal anesthesia, chemotherapy, or pain management applications. This route is also used to introduce drugs that fight certain infections, particularly post-neurosurgical. The drug needs to be given this way to avoid being stopped by the blood–brain barrier. The same drug given orally must enter the blood stream and may not be able to pass out and into the brain. Drugs given by the intrathecal route often have to be compounded specially by a pharmacist or technician because they cannot contain any preservative or other potentially harmful inactive ingredients that are sometimes found in standard injectable drug preparations. The route of administration is sometimes simply referred to as "intrathecal"; however, the term is also an adjective that refers to something occurring in or ...
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Meningitis
Meningitis is acute or chronic inflammation of the protective membranes covering the brain and spinal cord, collectively called the meninges. The most common symptoms are fever, headache, and neck stiffness. Other symptoms include confusion or altered consciousness, nausea, vomiting, and an inability to tolerate light or loud noises. Young children often exhibit only nonspecific symptoms, such as irritability, drowsiness, or poor feeding. A non-blanching rash (a rash that does not fade when a glass is rolled over it) may also be present. The inflammation may be caused by infection with viruses, bacteria or other microorganisms. Non-infectious causes include malignancy (cancer), subarachnoid haemorrhage, chronic inflammatory disease (sarcoidosis) and certain drugs. Meningitis can be life-threatening because of the inflammation's proximity to the brain and spinal cord; therefore, the condition is classified as a medical emergency. A lumbar puncture, in which a needle is inserte ...
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Radcliffe Infirmary
The Radcliffe Infirmary was a hospital in central north Oxford, England, located at the southern end of Woodstock Road on the western side, backing onto Walton Street. History The initial proposals to build a hospital in Oxford were put forward at a meeting of the Radcliffe Trustees, who were administering John Radcliffe's estate valued at £4,000, in 1758. The facility was constructed on land given by Thomas Rowney, one of the two members of parliament for Oxford. The foundation stone was laid on 27 August 1761 and the new facility was officially opened on 18 October 1770. A fountain of the Greek god Triton was placed in front of the main infirmary building in 1858 and the Oxford Eye Hospital was established on the site in 1886.A brief history of the Nuffield Laboratory of Ophthalmology
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Neurosurgery
Neurosurgery or neurological surgery, known in common parlance as brain surgery, is the medical specialty concerned with the surgical treatment of disorders which affect any portion of the nervous system including the brain, spinal cord and peripheral nervous system. Education and context In different countries, there are different requirements for an individual to legally practice neurosurgery, and there are varying methods through which they must be educated. In most countries, neurosurgeon training requires a minimum period of seven years after graduating from medical school. United States In the United States, a neurosurgeon must generally complete four years of undergraduate education, four years of medical school, and seven years of residency (PGY-1-7). Most, but not all, residency programs have some component of basic science or clinical research. Neurosurgeons may pursue additional training in the form of a fellowship after residency, or, in some cases, as a senior resid ...
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