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Beckman Coulter, Inc. is a Danaher Corporation company that develops, manufactures, and markets products relevant to biomedical testing. It operates in the industries of Diagnosis, diagnostics under the brand name Beckman Coulter and life sciences under the brand name Beckman Coulter Life Sciences. The company was established in 1935 as National Technical Laboratories, and has become an international company through growth and acquisitions of other life sciences organizations. The company employs over 12,000 people, with $5.8 billion in annual sales by 2017. It is currently headquartered in Brea, California. Beckman Coulter was acquired by Danaher Corporation in 2011. History The company was founded by Caltech professor Arnold O. Beckman in 1935 as National Technical Laboratories to commercialize a pH meter that he had invented. In the 1940s, Beckman changed the name to Arnold O. Beckman, Inc. to sell oxygen analyzers, the ''Helipot'' precision potentiometer, and spectrophotomet ...
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Danaher Corporation
Danaher Corporation is an American global conglomerate founded in 1984 by brothers Steven and Mitchell Rales. Headquartered in Washington, D.C., the company designs, manufactures, and markets medical, industrial, and commercial products and services.Drummond, Bob (2 April 2004)Takeover Wizards ''New Zealand Herald''Valdez, Angela (6 June 2008)A Very Private Collection ''Washington City Paper'' Danaher was among the first companies in North America to adopt Kaizen principles, a Japanese lean manufacturing philosophy of continuous improvement and efficiency.Fox, Justin (19 May 2015)What Makes Danaher Corp. Such a Star? ''Bloomberg'' (discussing kaizen and privacy of company) The company held $78.5 billion in assets . History Early years The company's origins go back to a Massachusetts real estate investment trust organized in 1969 as DMG, Inc. In 1978, DMG, Inc. was reorganized as a Florida corporation and changed its name to Diversified Mortgage Investors, Inc. DMG had be ...
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Mountain View, Santa Clara County, California
Mountain View is a city in Santa Clara County, California, United States, part of the San Francisco Bay Area. Named for its views of the Santa Cruz Mountains, the population was 82,376 at the 2020 census. Mountain View was integral to the early history and growth of Silicon Valley, and is the location of many high technology companies. In 1956, William Shockley established Shockley Semiconductor Laboratory in Mountain View, the first company to develop silicon semiconductor devices in Silicon Valley. Mountain View houses the headquarters of many of the world's largest technology companies, including Google and Alphabet Inc., Unicode Consortium, Intuit, Applied Intuition, NASA Ames Research Center, and former or existing headquarters for Symantec, 23andMe, LinkedIn, Samsung, Quora and Synopsys. History The fertile land between the Santa Cruz Mountains and the shores of the southern San Francisco Bay once supported multiple villages of the indigenous Ohlone people. S ...
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Palo Alto, California
Palo Alto ( ; Spanish language, Spanish for ) is a charter city in northwestern Santa Clara County, California, United States, in the San Francisco Bay Area, named after a Sequoia sempervirens, coastal redwood tree known as El Palo Alto. The city of Palo Alto was incorporated in 1894 by the American industrialist Leland Stanford and his wife, Jane Stanford, when they founded Stanford University in memory of their only child, Leland Stanford Jr. Palo Alto later expanded and now borders East Palo Alto, California, East Palo Alto, Mountain View, California, Mountain View, Los Altos, California, Los Altos, Los Altos Hills, California, Los Altos Hills, Stanford, California, Stanford, Portola Valley, California, Portola Valley, and Menlo Park, California, Menlo Park. As of the 2020 United States census, the population was 68,572. Palo Alto has one of the highest costs of living in the United States, and its residents are among the most educated in the country. However, it has ...
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William Shockley
William Bradford Shockley ( ; February 13, 1910 – August 12, 1989) was an American solid-state physicist, electrical engineer, and inventor. He was the manager of a research group at Bell Labs that included John Bardeen and Walter Houser Brattain. The three scientists were jointly awarded the 1956 Nobel Prize in Physics for "their researches on semiconductors and their discovery of the transistor effect". Partly as a result of Shockley's attempts to commercialize a new transistor design in the 1950s and 1960s, California's Silicon Valley became a hotbed of electronics innovation. He recruited brilliant employees, but quickly alienated them with his autocratic and erratic management; they left and founded major companies in the industry. In his later life, while a professor of electrical engineering at Stanford University and afterward, Shockley became known as a Racism, racist and Eugenics, eugenicist. Early life and education Shockley was born to American parents in Londo ...
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California Institute Of Technology
The California Institute of Technology (branded as Caltech) is a private research university in Pasadena, California, United States. The university is responsible for many modern scientific advancements and is among a small group of institutes of technology in the United States that are devoted to the instruction of pure and applied sciences. The institution was founded as a preparatory and vocational school by Amos G. Throop in 1891 and began attracting influential scientists such as George Ellery Hale, Arthur Amos Noyes, and Robert Andrews Millikan in the early 20th century. The vocational and preparatory schools were disbanded and spun off in 1910, and the college assumed its present name in 1920. In 1934, Caltech was elected to the Association of American Universities, and the antecedents of NASA's Jet Propulsion Laboratory, which Caltech continues to manage and operate, were established between 1936 and 1943 under Theodore von Kármán. Caltech has six academic divisi ...
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Transistor
A transistor is a semiconductor device used to Electronic amplifier, amplify or electronic switch, switch electrical signals and electric power, power. It is one of the basic building blocks of modern electronics. It is composed of semiconductor material, usually with at least three terminal (electronics), terminals for connection to an electronic circuit. A voltage or Electric current, current applied to one pair of the transistor's terminals controls the current through another pair of terminals. Because the controlled (output) power can be higher than the controlling (input) power, a transistor can amplify a signal. Some transistors are packaged individually, but many more in miniature form are found embedded in integrated circuits. Because transistors are the key active components in practically all modern electronics, many people consider them one of the 20th century's greatest inventions. Physicist Julius Edgar Lilienfeld proposed the concept of a field-effect transisto ...
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Shockley Semiconductor Laboratory
Shockley Semiconductor Laboratory, later known as Shockley Transistor Corporation, was a pioneering semiconductor developer founded by William Shockley, and funded by Beckman Instruments, Inc., in 1955. It was the first high technology company, in what came to be known as Silicon Valley, to work on silicon-based semiconductor devices. In 1957, the Traitorous eight, eight leading scientists resigned, and became the core of what would later become Fairchild Semiconductor. Shockley Semiconductor never recovered from this departure; it was purchased by Clevite in 1960, then sold to ITT Corporation, ITT in 1968, and shortly after, officially closed. The company's headquarters building was repurposed as a retail store. By 2015 plans were made to demolish the site to develop a new building complex. By 2017, the site was redeveloped with new signage marking it as the "Real Birthplace of Silicon Valley." Shockley's return to California William Shockley received his undergraduate de ...
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Centrifuge
A centrifuge is a device that uses centrifugal force to subject a specimen to a specified constant force - for example, to separate various components of a fluid. This is achieved by spinning the fluid at high speed within a container, thereby separating fluids of different densities (e.g. cream from milk) or liquids from solids. It works by causing denser substances and particles to move outward in the radial direction. At the same time, objects that are less dense are displaced and moved to the centre. In a laboratory centrifuge that uses sample tubes, the radial acceleration causes denser particles to settle to the bottom of the tube, while low-density substances rise to the top. A centrifuge can be a very effective filter that separates contaminants from the main body of fluid. Industrial scale centrifuges are commonly used in manufacturing and waste processing to sediment suspended solids, or to separate immiscible liquids. An example is the cream separator found in da ...
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Ultracentrifuge
An ultracentrifuge is a centrifuge optimized for spinning a rotor at very high speeds, capable of generating acceleration as high as (approx. ). There are two kinds of ultracentrifuges, the preparative and the analytical ultracentrifuge. Both classes of instruments find important uses in molecular biology, biochemistry, and polymer science.Susan R. Mikkelsen & Eduardo Cortón. Bioanalytical Chemistry, Ch. 13. Centrifugation Methods. John Wiley & Sons, Mar 4, 2004, pp. 247-267. History In 1924 Theodor Svedberg built a centrifuge capable of generating 7,000 g (at 12,000 rpm), and called it the ultracentrifuge, to juxtapose it with the Ultramicroscope that had been developed previously. In 1925-1926 Svedberg constructed a new ultracentrifuge that permitted fields up to 100,000 g (42,000 rpm). Modern ultracentrifuges are typically classified as allowing greater than 100,000 g. Svedberg won the Nobel Prize in Chemistry in 1926 for his research on colloids and proteins using the ultrac ...
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Apollo Guidance Computer
The Apollo Guidance Computer (AGC) was a digital computer produced for the Apollo program that was installed on board each Apollo command module (CM) and Apollo Lunar Module (LM). The AGC provided computation and electronic interfaces for guidance, navigation, and control of the spacecraft. The AGC was among the first computers based on silicon integrated circuits (ICs). The computer's performance was comparable to the first generation of home computers from the late 1970s, such as the Apple II, TRS-80, and Commodore PET. At around 2 cubic feet in size, AGC held 4,100 IC packages. The AGC has a 16-bit Word (computer architecture), word length, with 15 data bits and one [ arity bit. Most of the software on the AGC is stored in a special read-only memory known as core rope memory, fashioned by weaving wires through and around magnetic cores, though a small amount of read/write core memory is available. Astronauts communicated with the AGC using a numeric display and keyboard call ...
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Real-time Simulation
Real-time simulation refers to a computer model of a physical system that can execute at the same rate as actual "wall clock" time. In other words, the computer model runs at the same rate as the actual physical system. For example, if a tank takes 10 minutes to fill in the real world, it would take 10 minutes to fill in the simulation as well. Real-time simulation occurs commonly in computer gaming, but also is important in the industrial market for operator training and off-line controller tuning. Computer languages like LabVIEW, VisSim and Simulink allow quick creation of such real-time simulations and have connections to industrial displays and programmable logic controllers via OLE for process control or digital and analog I/O cards. Several real-time simulators are available on the market including xPC Target and RT-LAB for mechatronic systems, Simulink for power electronic simulation, and RTDS for power grid simulation. Definition In a real-time simulation, the simul ...
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