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Hela Långa Dagen
HeLa () is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells are durable and prolific, allowing for extensive applications in scientific study. The line is derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a 31-year-old African American mother of five, after whom the line is named. Lacks died of cancer on October 4, 1951. The cells from Lacks's cancerous cervical tumor were taken without her knowledge, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would survive for only a few days, but cells from Lacks's tumor behaved differently. History Origin In 1951, Henrietta Lacks was admitted to the Johns Hopkins Hospital with symptoms of irregular vaginal bleeding; she was subsequently treated for cervical can ...
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Strain (biology)
In biology, a strain is a genetic variant, a subtype or a culture within a biological species. Strains are often seen as inherently artificial concepts, characterized by a specific intent for genetic isolation. This is most easily observed in microbiology where strains are derived from a single cell colony and are typically quarantined by the physical constraints of a Petri dish. Strains are also commonly referred to within virology, botany, and with rodents used in experimental studies. Microbiology and virology It has been said that "there is no universally accepted definition for the terms 'strain', ' variant', and 'isolate' in the virology community, and most virologists simply copy the usage of terms from others". A strain is a genetic variant or subtype of a microorganism such as a bacterial strain or a specific strain of a virus, or fungus. For example, a "flu strain" is a certain biological form of the influenza or "flu" virus. These flu strains are characterized ...
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Baltimore City Paper
''Baltimore City Paper'' was a free alternative weekly newspaper published in Baltimore, Maryland, United States, founded in 1977 by Russ Smith and Alan Hirsch. The most recent owner was the Baltimore Sun Media Group, which purchased the paper in 2014 from Times-Shamrock Communications, which had owned the newspaper since 1987. It was distributed on Wednesdays in distinctive yellow boxes found throughout the Baltimore area. The paper folded in 2017, due to the collapse of advertising revenue income to print media. The Media Group's closure announcement happened at the same meeting immediately after recognizing ''City Paper'' staff joining the Washington-Baltimore News Guild. History Russ Smith and Alan Hirsch started the Baltimore City Paper in May 1977 while students at Johns Hopkins University. It was originally named the ''City Squeeze'', and Smith and Hirsch published it using the offices of the Johns Hopkins student newspaper. In 1978, they took the paper out of the u ...
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University Of Colorado, Denver
The University of Colorado Denver (CU Denver) is a public research university located in downtown Denver, Colorado. It is part of the University of Colorado system. Established in 1912 as an extension of the University of Colorado Boulder, CU Denver attained university status and became an independent institution in 1973. CU Denver is classified among R1: Doctoral Universities – Very High Research Activity. The university's graduate programs award more master's degrees than any other institution in the state, serving roughly 5,000 students annually. CU Denver makes up one-third of the Auraria Campus in downtown Denver, along with the Metropolitan State University of Denver and the Community College of Denver. History University of Colorado System Anschutz Medical Campus The University of Colorado created the Department of Medicine and Surgery in September 1883 in the Old Main building on the Boulder campus. The Department of Nursing opened in 1898. By 1892, the last ...
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Philip I
Philip(p) I may refer to: * Philip I of Macedon (7th century BC) * Philip I Philadelphus (between 124 and 109 BC–83 or 75 BC) * Philip the Arab (c. 204–249), Roman Emperor * Philip I of France (1052–1108) * Philip I (archbishop of Cologne) (1130–1191) * Philip I, Count of Flanders (1143–1191) * Philip I of Namur, (1175–1212) * Philip I, Count of Boulogne (1200–1235) * Philip I, Count of Savoy (1207–1285) * Philip I, Latin Emperor (1243–1283) * Philip IV of France, aka Philip I of Navarre (1268–1314) * Philip I of Piedmont, known as Philip of Savoy (1278–1334) lord of Piedmont * Philip I, Prince of Taranto (1278–1331/2) * Philip I, Count of Auvergne (1323–1346) * Philip I, Duke of Burgundy (1346–1361) * Philipp I, Count of Nassau-Weilburg (1368–1429) * Philip I, Metropolitan of Moscow (died 1473) * Philipp I, Count of Katzenelnbogen (1402–1479) * Philip I, Duke of Brabant (1404–1430) * Philipp I, Count of Hanau-Lichtenberg (1417–1480) * ...
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Theodore Puck
Theodore Thomas Puck (September 24, 1916 – November 6, 2005) was an American geneticist born in Chicago, Illinois. He attended Chicago public schools and obtained his bachelors, masters, and doctoral degree from the University of Chicago. His PhD work was on the laws governing the impact of an electron upon an atom and his doctoral adviser was James Franck. During WW II Puck stayed at the University of Chicago. There he worked in the laboratory of Oswald H. Robertson on the study of how bacteria and viruses can spread through the air and on dust particles. After a postdoc position in the laboratory of Renato Dulbecco, Puck was recruited in 1948 to establish and chair the University of Colorado Medical School's department of biophysics. He retired from the University of Colorado Medical School in 1995 as professor emeritus, but continued to do laboratory work there until a few weeks before his death. Puck was an early pioneer of "somatic cell genetics" and single-cell plat ...
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Ultragenyx
Ultragenyx Pharmaceutical Inc. is an American biopharmaceutical company involved in the research and development of novel products for treatment of rare and ultra-rare genetic diseases for which there are typically no approved treatments and high unmet medical need. The company works with multiple drug modalities including biologics, small molecule, gene therapies, and ASO and mRNAs in the disease categories of bone, endocrine, metabolic, muscle and CNS diseases. Ultragenyx is based in Novato, CA and Brisbane, CA and has a presence in the Boston area, including a gene therapy plant under construction as of 2021. The company’s Latin American headquarters is located in Miami. Ultragenyx collaborates on product development with other companies including GeneTX, Kyowa Hakko Kirin, Mereo Biopharma and Daiichi Sankyo. Ultragenyx has three products Burosumab, Triheptanoin and Vestronidase alfa that have received FDA approval and several others currently in clinical trials. Th ...
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Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is an American life science and clinical research company. It is a global supplier of analytical instruments, clinical development solutions, specialty diagnostics, laboratory, pharmaceutical and biotechnology services. Based in Waltham, Massachusetts, Thermo Fisher was formed through the merger of Thermo Electron and Fisher Scientific in 2006. Thermo Fisher Scientific has acquired other reagent, consumable, instrumentation, and service providers, including Life Technologies Corporation (2013), Alfa Aesar (2015), Affymetrix (2016), FEI Company (2016), BD Advanced Bioprocessing (2018), and PPD (2021). , the company had a market capitalization of $202 billion. It ranked 97th on the ''Fortune'' 500 list based on its 2022 annual revenue of US$44.92 billion. History Predecessors and merger Thermo Electron was co-founded in 1956 by George N. Hatsopoulos and Peter M Nomikos. Hatsopoulos received a PhD from MIT in mechanical engineering ...
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Common Rule
The Common Rule is a 1991 rule of ethics in the United States regarding biomedical and behavioral research involving human subjects. A significant revision became effective July 2018. It governed Institutional Review Boards for oversight of human research and followed the 1975 revision of the Declaration of Helsinki; it is encapsulated in the 1991 revision to the U.S. Department of Health and Human Services Title 45 CFR 46 (Public Welfare) Subparts A, B, C and D. Subpart A. The Common Rule is the baseline standard of ethics by which any government-funded research in the US is held; nearly all U.S. academic institutions hold their researchers to these statements of rights regardless of funding. Background The Common Rule is a 1991 rule of ethics (revised in 2018) regarding biomedical and behavioral research involving human subjects in the United States. The regulations governing Institutional Review Boards for oversight of human research followed the 1975 revision of the Declara ...
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Moore V
Moore may refer to: Language * Mooré language, spoken in West Africa People * Moore (surname) ** List of people with surname Moore * Moore Crosthwaite (1907–1989), a British diplomat and ambassador * Moore Disney (1765–1846), a senior officer in the British Army * Moore Powell (died c. 1573), a Welsh politician Places Australia * Moore, Queensland, a town in the Somerset Region *Division of Moore, an electoral division in Western Australia Greenland * Moore Glacier United Kingdom * Moore, Cheshire, England United States * Moore, Idaho * Moore, Indiana * Moore, Montana * Moore, New Jersey * Moore, Oklahoma * Moore Township, Pennsylvania * Moore, South Carolina * Moore, Texas * Moore, Utah * Moore, Washington * Moore, West Virginia * Moore County, North Carolina * Moore County, Tennessee * Moore County, Texas * Moore Haven, Florida * Banning, California, formerly known as Moore City Schools Australia * Moore Theological College, Sydney, Australia Unit ...
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Supreme Court Of California
The Supreme Court of California is the Supreme court, highest and final court of appeals in the judiciary of California, courts of the U.S. state of California. It is headquartered in San Francisco at the Earl Warren Building, but it regularly holds sessions in Los Angeles and Sacramento. Its decisions are binding on all other California State court (United States), state courts. Since 1850, the court has issued many influential decisions in a variety of areas including torts, property law, property, Civil and political rights, civil and constitutional rights, and criminal law. Composition Under the original 1849 California Constitution, the Court started with a chief justice and two associate justices. The Court was expanded to five justices in 1862. Under the current 1879 constitution, the Court expanded to six associate justices and one chief justice, for the current total of seven. The justices are appointed by the Governor of California and are subject to retention electi ...
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Informed Consent
Informed consent is an applied ethics principle that a person must have sufficient information and understanding before making decisions about accepting risk. Pertinent information may include risks and benefits of treatments, alternative treatments, the patient's role in treatment, and their Right to refuse medical treatment, right to refuse treatment. In most systems, healthcare providers have a legal and ethical responsibility to ensure that a patient's consent is informed. This principle applies more broadly than healthcare intervention, for example to conduct research, to disclose a person's medical information, or to participate in high risk sporting and recreational activities. Within the United States, definitions of informed consent vary, and the standard required is generally determined by the state. As of 2016, nearly half of the states adopted a reasonable patient standard, in which the informed consent process is viewed from the patient's perspective. These standards ...
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