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Haplogroup M (mtDNA)
Haplogroup M is a human mitochondrial DNA (mtDNA) haplogroup. An enormous haplogroup spanning all the continents, the macro-haplogroup M, like its sibling the macro-haplogroup N, is a descendant of the haplogroup L3. All mtDNA haplogroups considered native outside of Africa are descendants of either haplogroup M or its sibling haplogroup N. Haplogroup M is relatively young, having a younger most recent common ancestor date than some subclades of haplogroup N such as haplogroup R. Origins There is a debate concerning the geographical origins of Haplogroup M and its sibling haplogroup N. Both lineages are thought to have been the main surviving lineages involved in the out of Africa migration (or migrations) because all indigenous lineages found outside Africa belong to haplogroup M or haplogroup N. Scientists are unsure whether the mutations that define haplogroups M and N occurred in Africa before the exit from Africa or in Asia after the exit from Africa. Determining th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Mitochondrial DNA Haplogroup
In human genetics, a human mitochondrial DNA haplogroup is a haplogroup defined by differences in human mitochondrial DNA. Haplogroups are used to represent the major branch points on the mitochondrial phylogenetic tree. Understanding the evolutionary path of the female lineage has helped population geneticists trace the matrilineal inheritance of modern humans back to human origins in Africa and the subsequent spread around the globe. The letter names of the haplogroups (not just mitochondrial DNA haplogroups) run from A to Z. As haplogroups were named in the order of their discovery, the alphabetical ordering does not have any meaning in terms of actual genetic relationships. The hypothetical woman at the root of all these groups (meaning just the mitochondrial DNA haplogroups) is the matrilineal most recent common ancestor (MRCA) for all currently living humans. She is commonly called Mitochondrial Eve. The rate at which mitochondrial DNA mutates is known as the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L3 (mtDNA)
Haplogroup L3 is a Human mitochondrial DNA haplogroup, human mitochondrial DNA (mtDNA) haplogroup. The clade has played a pivotal role in the early dispersal of anatomically modern humans. It is strongly associated with the Southern Dispersal, out-of-Africa migration of modern humans of about 70–50,000 years ago. It is inherited by all modern non-African populations, as well as by some populations in Africa. Origin Haplogroup L3 arose close to 70,000 years ago, near the time of the Southern Dispersal, recent out-of-Africa event. This dispersal originated in East Africa and expanded to West Asia, and further to South and Southeast Asia in the course of a few millennia, and some research suggests that L3 participated in this migration out of Africa. A 2007 estimate for the age of L3 suggested a range of 104–84,000 years ago. More recent analyses, including Soares et al. (2012) arrive at a more recent date, of roughly 70–60,000 years ago. Soares et al. also suggest that L3 m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup L2 (mtDNA)
Haplogroup L2 is a Human mitochondrial DNA haplogroup, human mitochondrial DNA (mtDNA) haplogroup with a widespread modern distribution, particularly in Subequatorial Africa. Its L2a subclade is a somewhat frequent and widely distributed mtDNA cluster on the continent, as well as among those in the Americas. Origin L2 is a common lineage in Africa. It is believed to have evolved between 87,000 and 107,000 years ago or approx. 90,000 YBP. Its age and widespread distribution and diversity across the continent makes its exact origin point within Africa difficult to trace with any confidence. Several L2 haplotypes observed in Guineans and other West Africa populations shared genetic matches with East Africa and North Africa. An origin for L2b, L2c, L2d and L2e in West or Central Africa seems likely. The early diversity of L2 can be observed all over the African Continent, but as we can see in Subclades section below, the highest diversity is found in West Africa. Most of subclades are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Toomas Kivisild
Toomas Kivisild (born 11 August 1969, in Tapa, Estonia) is an Estonian population geneticist. He graduated as a biologist and received his PhD in Genetics, from University of Tartu, Estonia, in 2000. Since then he has worked as a postdoctoral research fellow in the School of Medicine, at Stanford University (2002-3), Estonian Biocentre (since 2003), as the Professor of Evolutionary Biology, University of Tartu (2005-6), and as a Lecturer and Reader in Human Evolutionary Genetics in the Department of Archaeology and Anthropology at the University of Cambridge (2006-2018). From 2018 he is a professor in the Department of Human Genetics at KU Leuven KU Leuven (Katholieke Universiteit Leuven) is a Catholic research university in the city of Leuven, Leuven, Belgium. Founded in 1425, it is the oldest university in Belgium and the oldest university in the Low Countries. In addition to its mai ... and a senior researcher at the Institute of Genomics, University of Tartu. Kivisild ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetic Admixture
Genetic admixture occurs when previously isolated populations interbreed resulting in a population that is descended from multiple sources. It can occur between species, such as with hybrids, or within species, such as when geographically distant individuals migrate to new regions. It results in gene pool that is a mix of the source populations. Examples Climatic cycles facilitate genetic admixture in cold periods and genetic diversification in warm periods. Natural flooding can cause genetic admixture within populations of migrating fish species. Genetic admixture may have an important role for the success of populations that colonise a new area and interbreed with individuals of native populations. Mapping Admixture mapping is a method of gene mapping that uses a population of mixed ancestry (an admixed population) to find the genetic loci that contribute to differences in diseases or other phenotypes found between the different ancestral populations. The method is best app ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eurasian
Eurasia ( , ) is a continental area on Earth, comprising all of Europe and Asia. According to some geographers, physiographically, Eurasia is a single supercontinent. The concept of Europe and Asia as distinct continents dates back to antiquity, but their borders have historically been subject to change. For example, the ancient Greeks originally included Africa in Asia but classified Europe as separate land. Eurasia is connected to Africa at the Suez Canal, and the two are sometimes combined to describe the largest contiguous landmass on Earth, Afro-Eurasia. History Eurasia has been the host of many ancient civilizations, including those based in Mesopotamia, Egypt, the Indus Valley and China. In the Axial Age (mid- first millennium BCE), a continuous belt of civilizations stretched through the Eurasian subtropical zone from the Atlantic to the Pacific. This belt became the mainstream of world history for two millennia. New connections emerged between the subregions of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Haplogroup U (mtDNA)
Haplogroup U is a human mitochondrial DNA haplogroup (mtDNA). The clade arose from haplogroup R, likely during the early Upper Paleolithic. Its various subclades (labelled U1–U9, diverging over the course of the Upper Paleolithic) are found widely distributed across Northern and Eastern Europe, Central, Western and South Asia, as well as North Africa, the Horn of Africa, and the Canary Islands. Origins Haplogroup U descends from the haplogroup R mtDNA branch of the phylogenetic tree. The defining mutations (A11467G, A12308G, G12372A) are estimated to have arisen between 43,000 and 50,000 years ago, in the early Upper Paleolithic (around 46,530 ± 3,290 years before present, with a 95% confidence interval per Behar et al., 2012). Ancient DNA classified as belonging to the U* mitochondrial haplogroup has been recovered from human skeletal remains found in Western Siberia, which have been dated to c. 45,000 years ago. The mitogenome (33-fold coverage) of the Peştera Mu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tibet
Tibet (; ''Böd''; ), or Greater Tibet, is a region in the western part of East Asia, covering much of the Tibetan Plateau and spanning about . It is the homeland of the Tibetan people. Also resident on the plateau are other ethnic groups such as Mongols, Monpa people, Monpa, Tamang people, Tamang, Qiang people, Qiang, Sherpa people, Sherpa, Lhoba people, Lhoba, and since the 20th century Han Chinese and Hui people, Hui. Tibet is the highest region on Earth, with an average elevation of . Located in the Himalayas, the highest elevation in Tibet is Mount Everest, Earth's highest mountain, rising above sea level. The Tibetan Empire emerged in the 7th century. At its height in the 9th century, the Tibetan Empire extended far beyond the Tibetan Plateau, from the Tarim Basin and Pamirs in the west, to Yunnan and Bengal in the southeast. It then divided into a variety of territories. The bulk of western and central Tibet (Ü-Tsang) was often at least nominally unified under a ser ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Asia
Central Asia is a region of Asia consisting of Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan. The countries as a group are also colloquially referred to as the "-stans" as all have names ending with the Persian language, Persian suffix "-stan" (meaning ) in both respective native languages and most other languages. The region is bounded by the Caspian Sea to the southwest, European Russia to the northwest, China and Mongolia to the east, Afghanistan and Iran to the south, and Siberia to the north. Together, the five Central Asian countries have a total population of around million. In the pre-Islamic and early Islamic eras ( and earlier) Central Asia was inhabited predominantly by Iranian peoples, populated by Eastern Iranian-speaking Bactrians, Sogdians, Khwarezmian language, Chorasmians, and the semi-nomadic Scythians and Dahae. As the result of Turkic migration, Central Asia also became the homeland for the Kazakhs, Kyrgyzs, Volga Tatars, Tatars, Turkmens, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caucasus
The Caucasus () or Caucasia (), is a region spanning Eastern Europe and Western Asia. It is situated between the Black Sea and the Caspian Sea, comprising parts of Southern Russia, Georgia, Armenia, and Azerbaijan. The Caucasus Mountains, including the Greater Caucasus range, have conventionally been considered as a natural barrier between Europe and Asia, bisecting the Eurasian landmass. Mount Elbrus, Europe's highest mountain, is situated in the Western Caucasus area of Russia. On the southern side, the Lesser Caucasus includes the Javakheti Plateau and the Armenian highlands. The Caucasus is divided into the North Caucasus and South Caucasus, although the Western Caucasus also exists as a distinct geographic space within the North Caucasus. The Greater Caucasus mountain range in the north is mostly shared by Russia and Georgia as well as the northernmost parts of Azerbaijan. The Lesser Caucasus mountain range in the south is mostly located on the territory of sout ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Iran
Iran, officially the Islamic Republic of Iran (IRI) and also known as Persia, is a country in West Asia. It borders Iraq to the west, Turkey, Azerbaijan, and Armenia to the northwest, the Caspian Sea to the north, Turkmenistan to the northeast, Afghanistan to the east, Pakistan to the southeast, and the Gulf of Oman and the Persian Gulf to the south. With a Ethnicities in Iran, multi-ethnic population of over 92 million in an area of , Iran ranks 17th globally in both List of countries and dependencies by area, geographic size and List of countries and dependencies by population, population. It is the List of Asian countries by area, sixth-largest country entirely in Asia and one of the world's List of mountains in Iran, most mountainous countries. Officially an Islamic republic, Iran is divided into Regions of Iran, five regions with Provinces of Iran, 31 provinces. Tehran is the nation's Capital city, capital, List of cities in Iran by province, largest city and financial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Levant
The Levant ( ) is the subregion that borders the Eastern Mediterranean, Eastern Mediterranean sea to the west, and forms the core of West Asia and the political term, Middle East, ''Middle East''. In its narrowest sense, which is in use today in archaeology and other cultural contexts, it is equivalent to Cyprus and a stretch of land bordering the Mediterranean Sea in Western AsiaGasiorowski, Mark (2016). ''The Government and Politics of the Middle East and North Africa''. p. 5: "... today the term ''Levantine'' can describe shared cultural products, such as Levantine cuisine or Levantine archaeology". .Steiner & Killebrew, p9: "The general limits ..., as defined here, begin at the Plain of 'Amuq in the north and extend south until the Wâdī al-Arish, along the northern coast of Sinai. ... The western coastline and the eastern deserts set the boundaries for the Levant ... The Euphrates and the area around Jebel el-Bishrī mark the eastern boundary of the northern Levant, as d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
