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Giulio Bizzozero
Giulio Bizzozero (; 20 March 1846 – 8 April 1901) was an Italian doctor and medical researcher. He was a pioneer of histology and is credited with the coining of the term platelets and identifying their function in coagulation. Background Bizzozero was born in Varese, Lombardy to Felice and Carolina Veratti. The family were involved in the Risorgimento, an older brother Cesare fought against Austria while Carolina served as a volunteer nurse. After high school, he studied medicine at the University of Pavia, where he performed histological and histopathological research under the guidance of Paolo Mantegazza (1831-1910) and the microscopist Eusebio Oehl. In 1866 he graduated from Pavia at the age of 20. He then travelled and worked with Rudolf Virchow in Berlin and Heinrich Frey in Zurich. In 1867, he was chosen as the chief of general pathology and histology at the University of Pavia. This institute trained many important Italian researchers, such as Camillo Golgi (184 ...
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Varese
Varese ( , , or ; lmo, label=Varesino, Varés ; la, Baretium; archaic german: Väris) is a city and ''comune'' in north-western Lombardy, northern Italy, north-west of Milan. The population of Varese in 2018 has reached 80,559. It is the capital of the Province of Varese. The hinterland or exurban part of the city is called ''Varesotto''. Geography The city of Varese lies at the foot of Sacro Monte di Varese, part of the Campo dei Fiori di Varese, Campo dei Fiori mountain range, that hosts an astronomical observatory, as well as the Prealpino Geophysical Centre. The village which is in the middle of the mountain is called Santa Maria del Monte because of the medieval sanctuary, which is reached through the avenue of the chapels of the Sacred Mountain. Varese is situated on seven hills: the San Pedrino Hill, the Giubiano Hill, the Campigli Hill, the Sant'Albino Hill, the Biumo Superiore Hill, Colle di Montalbano (Villa Mirabello) and the Hill of Miogni. The city also looks ...
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Rudolf Virchow
Rudolf Ludwig Carl Virchow (; or ; 13 October 18215 September 1902) was a German physician, anthropologist, pathologist, prehistorian, biologist, writer, editor, and politician. He is known as "the father of modern pathology" and as the founder of social medicine, and to his colleagues, the "Pope of medicine". Virchow studied medicine at the Friedrich Wilhelm University under Johannes Peter Müller. While working at the Charité hospital, his investigation of the 1847–1848 typhus epidemic in Upper Silesia laid the foundation for public health in Germany, and paved his political and social careers. From it, he coined a well known aphorism: "Medicine is a social science, and politics is nothing else but medicine on a large scale". His participation in the Revolution of 1848 led to his expulsion from Charité the next year. He then published a newspaper ''Die Medizinische Reform'' (''The Medical Reform''). He took the first Chair of Pathological Anatomy at the University of W� ...
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Fibrin
Fibrin (also called Factor Ia) is a fibrous, non-globular protein involved in the clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerize. The polymerized fibrin, together with platelets, forms a hemostatic plug or clot over a wound site. When the lining of a blood vessel is broken, platelets are attracted, forming a platelet plug. These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules, which in turn convert soluble fibrinogen in the serum into fibrin at the wound site. Fibrin forms long strands of tough insoluble protein that are bound to the platelets. Factor XIII completes the cross-linking of fibrin so that it hardens and contracts. The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot. Fibrin was discovered by Marcello Malpighi in 1666. Role in disease Excessive generation of fibrin due to activation of the coagulation cascade leads to ...
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Max Schultze
Max Johann Sigismund Schultze (25 March 1825 – 16 January 1874) was a German microscopic anatomist noted for his work on cell theory. Biography Schultze was born in Freiburg im Breisgau (Baden). He studied medicine at Greifswald and Berlin, and was appointed an associate professor of anatomy at Halle in 1854. Five years later he became a full professor of anatomy and histology and director of the Anatomical Institute at the University of Bonn. He died in Bonn on 16 January 1874; his successor at the anatomical institute being Adolph von La Valette-St. George. He was the older brother of obstetrician Bernhard Sigmund Schultze (1827–1919). He founded, in 1865, and edited the important "''Archiv für mikroskopische Anatomie''", to which he contributed many papers, and he advanced the subject generally, by refining on its technical methods. His works included: *''Beiträge zur Naturgeschichte der Turbellarien'' (1851). *''Uber den Organismus der Polythalamien'' (1854). *''Bei ...
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Peptic Ulcer Disease
Peptic ulcer disease (PUD) is a break in the inner lining of the stomach, the first part of the small intestine, or sometimes the lower esophagus. An ulcer in the stomach is called a gastric ulcer, while one in the first part of the intestines is a duodenal ulcer. The most common symptoms of a duodenal ulcer are waking at night with upper abdominal pain and upper abdominal pain that improves with eating. With a gastric ulcer, the pain may worsen with eating. The pain is often described as a burning or dull ache. Other symptoms include belching, vomiting, weight loss, or poor appetite. About a third of older people have no symptoms. Complications may include bleeding, perforation, and blockage of the stomach. Bleeding occurs in as many as 15% of cases. Common causes include the bacteria '' Helicobacter pylori'' and non-steroidal anti-inflammatory drugs (NSAIDs). Other, less common causes include tobacco smoking, stress as a result of other serious health conditions, Behçe ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic r ...
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1892
Events January–March * January 1 – Ellis Island begins accommodating immigrants to the United States. * February 1 - The historic Enterprise Bar and Grill was established in Rico, Colorado. * February 27 – Rudolf Diesel applies for a patent, on his compression ignition engine (the Diesel engine). * February 29 – St. Petersburg, Florida is incorporated as a town. * March 1 – Theodoros Deligiannis ends his term as Prime Minister of Greece, and Konstantinos Konstantopoulos takes office. * March 6– 8 – "Exclusive Agreement": Rulers of the Trucial States (Abu Dhabi, Dubai, Sharjah, Ajman, Ras al-Khaimah and Umm al-Quwain) sign an agreement, by which they become ''de facto'' British protectorates. * March 11 – The first basketball game is played in public, between students and faculty at the Springfield YMCA before 200 spectators. The final score is 5–1 in favor of the students, with the only goal for the faculty being scored by Amos Alonzo Stagg. * March ...
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Microscope
A microscope () is a laboratory instrument used to examine objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using a microscope. Microscopic means being invisible to the eye unless aided by a microscope. There are many types of microscopes, and they may be grouped in different ways. One way is to describe the method an instrument uses to interact with a sample and produce images, either by sending a beam of light or electrons through a sample in its optical path, by detecting photon emissions from a sample, or by scanning across and a short distance from the surface of a sample using a probe. The most common microscope (and the first to be invented) is the optical microscope, which uses lenses to refract visible light that passed through a thinly sectioned sample to produce an observable image. Other major types of microscopes are the fluorescence microscope, electron microscope (both the ...
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Italian Senate
The Senate of the Republic ( it, Senato della Repubblica), or simply the Senate ( it, Senato), is the upper house of the bicameral Italian Parliament (the other being the Chamber of Deputies). The two houses together form a perfect bicameral system, meaning they perform identical functions, but do so separately. Pursuant to the Articles 57, 58, and 59 of the Italian Constitution, the Senate has 200 elective members, of which 196 are elected from Italian constituencies, and 4 from Italian citizens living abroad. Furthermore, there is a small number (currently 6) of senators for life (''senatori a vita''), either appointed or ''ex officio''. It was established in its current form on 8 May 1948, but previously existed during the Kingdom of Italy as ''Senato del Regno'' ( Senate of the Kingdom), itself a continuation of the ''Senato Subalpino'' (Subalpine Senate) of Sardinia established on 8 May 1848. Members of the Senate are styled ''Senator'' or ''The Honourable Senator'' (Itali ...
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Humbert I
Umberto I ( it, Umberto Rainerio Carlo Emanuele Giovanni Maria Ferdinando Eugenio di Savoia; 14 March 1844 – 29 July 1900) was King of Italy from 9 January 1878 until his assassination on 29 July 1900. Umberto's reign saw Italy attempt colonial expansion into the Horn of Africa, successfully gaining Eritrea and Somalia despite being defeated by Abyssinia at the Battle of Adwa in 1896. In 1882, he approved the Triple Alliance with the German Empire and Austria-Hungary. He was deeply loathed in leftist circles for his conservatism and support of the Bava Beccaris massacre in Milan. He was especially hated by anarchists, who attempted to assassinate him during the first year of his reign. He was killed by another anarchist, Gaetano Bresci, two years after the Bava Beccaris massacre. Youth The son of Victor Emmanuel II and Archduchess Adelaide of Austria, Umberto was born in Turin, which was then capital of The Kingdom of Piedmont-Sardinia, on 14 March 1844, his father's ...
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Pneumonia
Pneumonia is an inflammatory condition of the lung primarily affecting the small air sacs known as alveoli. Symptoms typically include some combination of productive or dry cough, chest pain, fever, and difficulty breathing. The severity of the condition is variable. Pneumonia is usually caused by infection with viruses or bacteria, and less commonly by other microorganisms. Identifying the responsible pathogen can be difficult. Diagnosis is often based on symptoms and physical examination. Chest X-rays, blood tests, and culture of the sputum may help confirm the diagnosis. The disease may be classified by where it was acquired, such as community- or hospital-acquired or healthcare-associated pneumonia. Risk factors for pneumonia include cystic fibrosis, chronic obstructive pulmonary disease (COPD), sickle cell disease, asthma, diabetes, heart failure, a history of smoking, a poor ability to cough (such as following a stroke), and a weak immune system. ...
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Carlo Forlanini
Carlo Forlanini (11 June 1847 – 26 May 1918) was a medical doctor and professor at the Universities of Turin and Pavia. He was also the inventor of artificial pneumothorax, which was the primary treatment method of pulmonary tuberculosis for the first half of the 20th century and remained in use for severe cases of tuberculosis into the 1970s. Early life Carlo Forlanini was born in Milan on 11 June 1847, the eldest of four brothers and one sister. His father, Giuseppe Forlanini, was a physician belonging to a bourgeosie family of Milan. His mother, Marianna Rossi, died of pulmonary phthisis. Forlanini attended secondary school in Como, received his pre-doctoral education at Calchi Taeggi in Milan, then attended the Borromeo College at the University of Pavia. He interrupted his medical studies in 1866 to serve under Garibaldi as part of Garibaldi's unification of Italy. Forlanini participated in the Battle of Monte Suello and the Bezzecca. After his return to Pavia he p ...
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