Gösta Pettersson (biochemist)
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Gösta Pettersson (biochemist)
Gösta Pettersson is an emeritus professor in biochemistry at Lund University, Sweden. He was born in 1937 in Varberg, Sweden. He gained his Ph.D. at Lund University in 1966 on the basis of a thesis on toluquinones (natural products), and his early research was mainly concerned with fumigatin and other products of fungal metabolism. The turning point in Pettersson's career came in the wake of a kinetic study of an enzyme from ''Aspergillus fumigatus''. This paper has had virtually no influence on the progress of biochemistry, having never been cited in half a century except for once by its author, but it marked the beginning of the work on enzymes and kinetics for which Pettersson is best known. Alcohol dehydrogenase The major experimental focus of Pettersson's work on the kinetics of enzyme-catalysed reactions was the enzyme alcohol dehydrogenase, principally the enzyme from horse liver, but to some degree from other sources, such as the insect ''Drosophila melanogaster''. Hi ...
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Varberg
Varberg () is a Urban areas in Sweden, locality and the seat of Varberg Municipality, Halland County, Sweden, with 35,782 inhabitants in 2019. Varberg and all of Halland are well known for their "typical west coast" sandy beaches. In Varberg the coast changes from wide sandy beaches to rocky terrain that continues north into the Bohuslän archipelago and as far as the North Cape. Varberg is ranked as one of Sweden’s most beautiful cities. Geography Varberg is located on the Swedish west coast and is a popular beach and surfing destination for both Sweden and Europe. It has a main landmark in the large Fortress and Castle of Varberg. Through centuries many wars between Denmark and Sweden were fought here before Southern Sweden, including Varberg, became permanently Swedish in 1658 through the Treaty of Roskilde. It is a small town with architecture mainly from the turn of the century and has several green parks such as the Society Park (Societetsparken) and the English Park. ...
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Alcohol Dehydrogenase
Alcohol dehydrogenases (ADH) () are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+) to NADH. In humans and many other animals, they serve to break down alcohols that are otherwise toxic, and they also participate in the generation of useful aldehyde, ketone, or alcohol groups during the biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. Evolution Genetic evidence from comparisons of multiple organisms showed that a glutathione-dependent formaldehyde dehydrogenase, identical to a class III alcohol dehydrogenase (ADH-3/ADH5), is presumed to be the ancestral enzyme for the entire ADH family. Early on in evolution, an effective method for eliminating both endogenous and exogenous fo ...
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People Connected To Lund University
The term "the people" refers to the public or common mass of people of a polity. As such it is a concept of human rights law, international law as well as constitutional law, particularly used for claims of popular sovereignty. In contrast, a people is any plurality of persons considered as a whole. Used in politics and law, the term "a people" refers to the collective or community of an ethnic group or nation. Concepts Legal Chapter One, Article One of the Charter of the United Nations states that "peoples" have the right to self-determination. Though the mere status as peoples and the right to self-determination, as for example in the case of Indigenous peoples (''peoples'', as in all groups of indigenous people, not merely all indigenous persons as in ''indigenous people''), does not automatically provide for independent sovereignty and therefore secession. Indeed, judge Ivor Jennings identified the inherent problems in the right of "peoples" to self-determinat ...
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Swedish Biochemists
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) Swedish Open is a tennis tournament. Swedish Open may also refer to: * Swedish Open (badminton) * Swedish Open (table tennis) * Swedish Open (squash) * Swedish Open (darts) {{disambiguation ... {{disambig Language and nationality disambiguation pages ...
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Greenhouse Effect
The greenhouse effect occurs when greenhouse gases in a planet's atmosphere insulate the planet from losing heat to space, raising its surface temperature. Surface heating can happen from an internal heat source (as in the case of Jupiter) or come from an external source, such as its host star. In the case of Earth, the Sun emits shortwave radiation (sunlight) that passes through greenhouse gases to heat the Earth's surface. In response, the Earth's surface emits outgoing longwave radiation, longwave radiation that is mostly Absorption (electromagnetic radiation), absorbed by greenhouse gases. The absorption of longwave radiation prevents it from reaching space, reducing the rate at which the Earth can cool off. Without the greenhouse effect, the Earth's average surface temperature would be as cold as . This is of course much less than the 20th century average of about . In addition to naturally present greenhouse gases, burning of fossil fuels has greenhouse gas emissions, in ...
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Global Warming
Present-day climate change includes both global warming—the ongoing increase in global average temperature—and its wider effects on Earth's climate system. Climate change in a broader sense also includes previous long-term changes to Earth's climate. The current rise in global temperatures is driven by human activities, especially fossil fuel burning since the Industrial Revolution. Fossil fuel use, deforestation, and some agricultural and industrial practices release greenhouse gases. These gases absorb some of the heat that the Earth radiates after it warms from sunlight, warming the lower atmosphere. Carbon dioxide, the primary gas driving global warming, has increased in concentration by about 50% since the pre-industrial era to levels not seen for millions of years. Climate change has an increasingly large impact on the environment. Deserts are expanding, while heat waves and wildfires are becoming more common. Amplified warming in the Arctic has c ...
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Metabolite Channelling
Metabolite channeling is the passing of the intermediary metabolic product of one enzyme directly to another enzyme or active site without its release into solution. When several consecutive enzymes of a metabolic pathway channel substrates between themselves, this is called a metabolon. Channeling can make a metabolic pathway more rapid and efficient than it would be if the enzymes were randomly distributed in the cytosol, or prevent the release of unstable intermediates. It can also protect an intermediate from being consumed by competing reactions catalyzed by other enzymes. Mechanisms for channeling Channeling can occur in several ways. One possibility, which occurs in the pyruvate dehydrogenase complex, is by a substrate being attached to a flexible arm that moves between several active sites (not very likely). Another possibility is by two active sites being connected by a tunnel through the protein and the substrate moving through the tunnel; this is seen in tryptophan syntha ...
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Judith Klinman
Judith P. Klinman (born April 17, 1941, in Philadelphia, Pennsylvania) is an American chemist, biochemist, and molecular biologist known for her work on enzyme catalysis. She became the first female professor in the physical sciences at the University of California, Berkeley in 1978, where she is now Professor of the Graduate School and Chancellor's Professor. In 2012, she was awarded the National Medal of Science by President Barack Obama. She is a member of the National Academy of Sciences, American Academy of Arts and Sciences, American Association for the Advancement of Science, and the American Philosophical Society. Early life Klinman was born April 17, 1941, in Philadelphia, Pennsylvania. When Klinman was two years old, her biological father left the family. Klinman's mother sold her house and possessions and moved with Klinman to Miami Beach, Florida, for a time, before returning to Philadelphia to find work. Klinman's mother then remarried, and so she was raised by her ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (an insect of the Order (biology), order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly", "pomace fly", or "banana fly". In the wild, ''D. melanogaster'' are attracted to rotting fruit and fermenting beverages, and are often found in orchards, kitchens and pubs. Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and Life history theory, life history evolution. ''D. melanogaster'' was the first animal to be Fruit flies in space, launched into space in 1947. As of 2017, six Nobel Prizes have been awarded to drosophilists for their work using the insect. ''Drosophila melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with on ...
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Aspergillus Fumigatus
''Aspergillus fumigatus'' is a species of fungus in the genus ''Aspergillus'', and is one of the most common ''Aspergillus'' species to cause disease in individuals with an immunodeficiency. ''Aspergillus fumigatus'', a saprotroph widespread in nature, is typically found in soil and decaying organic matter, such as compost heaps, where it plays an essential role in carbon and nitrogen recycling. Colonies of the fungus produce from conidiophores; thousands of minute grey-green conidia (2–3 μm) which readily become airborne. For many years, ''A. fumigatus'' was thought to only reproduce asexually, as neither mating nor meiosis had ever been observed. In 2008, ''A. fumigatus'' was shown to possess a fully functional sexual reproductive cycle, 145 years after its original description by Fresenius. Although ''A. fumigatus'' occurs in areas with widely different climates and environments, it displays low genetic variation and a lack of population genetic differentiation on a global s ...
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Halland County
Halland County (, ) is a county ('' län'') on the western coast of Sweden. It corresponds roughly to the cultural and historical province of Halland. The capital is Halmstad. Prince Julian, the son of Prince Carl Philip, is Duke of Halland. It borders the counties of Västra Götaland, Jönköping, Kronoberg, Scania and the sea of the Kattegat. Heraldry The County of Halland inherited its coat of arms from the province of Halland. When it is shown with a royal crown it represents the County Administrative Board. Province Counties mainly serve administrative purposes in Sweden. The culture and history of the area is to be found in its provincial counterpart Halland. The county was designed with virtually the same boundaries as the province. The major exception is a part of Hylte Municipality, which belongs to the province of Småland. Geography * Genevadsån river Administration The main aim of the County Administrative Board is to fulfil the goals set in national po ...
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Natural Products
A natural product is a natural compound or substance produced by a living organism—that is, found in nature. In the broadest sense, natural products include any substance produced by life. Natural products can also be prepared by chemical synthesis (both semisynthesis and total synthesis and have played a central role in the development of the field of organic chemistry by providing challenging synthetic targets). The term ''natural product'' has also been extended for commercial purposes to refer to cosmetics, dietary supplements, and foods produced from natural sources without added artificial ingredients. Within the field of organic chemistry, the definition of natural products is usually restricted to organic compounds isolated from natural sources that are produced by the pathways of primary or secondary metabolism. Within the field of medicinal chemistry, the definition is often further restricted to secondary metabolites. Secondary metabolites (or specialized metab ...
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