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Grande Médaille
The Grande Médaille of the French Academy of Sciences, established in 1997, is awarded annually to a researcher who has contributed decisively to the development of science. It is the most prestigious of the Academy's awards, and is awarded in a different field each year. Its creation results from the combination of the original French Academy of Sciences Lalande Prize of 1802 with the Benjamin Valz Foundation Prize in 1970 and then with another 122 foundation prizes in 1997. Winners * 2021 - Katalin Karikó, biochemistry * 2018 - Jocelyn Bell Burnell, astrophysics * 2016 - Alexander Varshavsky, biochemistry * 2015 - ''no award'' * 2014 - Joel Lebowitz, physics and mathematics * 2013 - Joan A. Steitz, biochemistry * 2012 - Adi Shamir, cryptography * 2011 - Avelino Corma Canos, chemistry * 2010 - < ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
French Academy Of Sciences
The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French scientific research. It was at the forefront of scientific developments in Europe in the 17th and 18th centuries, and is one of the earliest Academies of Sciences. Currently headed by Patrick Flandrin (President of the Academy), it is one of the five Academies of the Institut de France. History The Academy of Sciences traces its origin to Colbert's plan to create a general academy. He chose a small group of scholars who met on 22 December 1666 in the King's library, near the present-day Bibliothèque Nationals, and thereafter held twice-weekly working meetings there in the two rooms assigned to the group. The first 30 years of the Academy's existence were relatively informal, since no statutes had as yet been laid down for the institution. In contrast to its Brit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hormone Receptor
A hormone receptor is a receptor molecule that binds to a specific chemical messenger . Hormone receptors are a wide family of proteins made up of receptors for thyroid and steroid hormones, retinoids and Vitamin D, and a variety of other receptors for various ligands, such as fatty acids and prostaglandins. Hormone receptors are of mainly two classes. Receptors for peptide hormones tend to be cell surface receptors built into the plasma membrane of cells and are thus referred to as trans membrane receptors. An example of this is Actrapid. Receptors for steroid hormones are usually found within the protoplasm and are referred to as intracellular or nuclear receptors, such as testosterone. Upon hormone binding, the receptor can initiate multiple signaling pathways, which ultimately leads to changes in the behavior of the target cells. Hormonal therapy and hormone receptors play a very large part in breast cancer treatment (therapy is not limited to only breast cancer). By influenci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Langlands
Robert Phelan Langlands, (; born October 6, 1936) is a Canadian mathematician. He is best known as the founder of the Langlands program, a vast web of conjectures and results connecting representation theory and automorphic forms to the study of Galois groups in number theory, for which he received the 2018 Abel Prize. He was an emeritus professor and occupied Albert Einstein's office at the Institute for Advanced Study in Princeton, until 2020 when he retired. Career Langlands was born in New Westminster, British Columbia, Canada, in 1936 to Robert Langlands and Kathleen J Phelan. He has two younger sisters (Mary b 1938; Sally b 1941). In 1945, his family moved to White Rock, near the US border, where his parents had a building supply and construction business. He graduated from Semiahmoo Secondary School and started enrolling at the University of British Columbia at the age of 16, receiving his undergraduate degree in Mathematics in 1957; he continued at UBC to receive an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Eschenmoser
Albert Jakob Eschenmoser (born 5 August 1925) is a Swiss organic chemist, best known for his work on the synthesis of complex heterocyclic natural compounds, most notably vitamin B12. In addition to his significant contributions to the field of organic synthesis, Eschenmoser pioneered work in the Origins of Life (OoL) field with work on the synthetic pathways of artificial nucleic acids. Before retiring in 2009, Eschenmoser held tenured teaching positions at the ETH Zurich and The Skaggs Institute for Chemical Biology at The Scripps Research Institute in La Jolla, California as well as visiting professorships at the University of Chicago, Cambridge University, and Harvard. Early work and Vitamin B12 Synthesis Eschenmoser began his scientific career as a graduate student in the laboratory of Leopold Ružička, at the Eidgenossische Technische Hochschule (ETH) in Zurich. Ruzicka was a notable organic chemist himself having been awarded the Nobel Prize in Chemistry in 1939 for hi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pion
In particle physics, a pion (or a pi meson, denoted with the Greek letter pi: ) is any of three subatomic particles: , , and . Each pion consists of a quark and an antiquark and is therefore a meson. Pions are the lightest mesons and, more generally, the lightest hadrons. They are unstable, with the charged pions and decaying after a mean lifetime of 26.033 nanoseconds ( seconds), and the neutral pion decaying after a much shorter lifetime of 85 attoseconds ( seconds). Charged pions most often decay into muons and muon neutrinos, while neutral pions generally decay into gamma rays. The exchange of virtual pions, along with vector, rho and omega mesons, provides an explanation for the residual strong force between nucleons. Pions are not produced in radioactive decay, but commonly are in high-energy collisions between hadrons. Pions also result from some matter–antimatter annihilation events. All types of pions are also produced in natural pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parity Violation
In physics, a parity transformation (also called parity inversion) is the flip in the sign of ''one'' spatial coordinate. In three dimensions, it can also refer to the simultaneous flip in the sign of all three spatial coordinates (a point reflection): :\mathbf: \beginx\\y\\z\end \mapsto \begin-x\\-y\\-z\end. It can also be thought of as a test for chirality of a physical phenomenon, in that a parity inversion transforms a phenomenon into its mirror image. All fundamental interactions of elementary particles, with the exception of the weak interaction, are symmetric under parity. The weak interaction is chiral and thus provides a means for probing chirality in physics. In interactions that are symmetric under parity, such as electromagnetism in atomic and molecular physics, parity serves as a powerful controlling principle underlying quantum transitions. A matrix representation of P (in any number of dimensions) has determinant equal to −1, and hence is distinct from a rotati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Richard Garwin
Richard Lawrence Garwin (born April 19, 1928) is an American physicist, best known as the author of the first hydrogen bomb design. In 1978, Garwin was elected a member of the National Academy of Engineering for contributing to the application of the latest scientific discoveries to innovative practical engineering applications contributing to national security and economic growth. Education Garwin received his bachelor's degree from the Case Institute of Technology in 1947, and two years later his Ph.D. from the University of Chicago under the supervision of Enrico Fermi at the age of 21. Another of Fermi's students, Marvin L. Goldberger, claims that Fermi said that "Garwin was the only true genius he had ever met". Career After graduating from the University of Chicago, Garwin joined the physics faculty there and spent summers as a consultant to Los Alamos National Laboratory working on nuclear weapons. Garwin was the author of the actual design used in the first hydrogen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signalling Peptides
In signal processing, a signal is a function that conveys information about a phenomenon. Any quantity that can vary over space or time can be used as a signal to share messages between observers. The ''IEEE Transactions on Signal Processing'' includes audio, video, speech, image, sonar, and radar as examples of signal. A signal may also be defined as observable change in a quantity over space or time (a time series), even if it does not carry information. In nature, signals can be actions done by an organism to alert other organisms, ranging from the release of plant chemicals to warn nearby plants of a predator, to sounds or motions made by animals to alert other animals of food. Signaling occurs in all organisms even at cellular levels, with cell signaling. Signaling theory, in evolutionary biology, proposes that a substantial driver for evolution is the ability of animals to communicate with each other by developing ways of signaling. In human engineering, signals are typi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cellular Biology
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electron Microscopy
An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a higher resolving power than light microscopes and can reveal the structure of smaller objects. A scanning transmission electron microscope has achieved better than 50 pm resolution in annular dark-field imaging mode and magnifications of up to about 10,000,000× whereas most light microscopes are limited by diffraction to about 200 nm resolution and useful magnifications below 2000×. Electron microscopes use shaped magnetic fields to form electron optical lens systems that are analogous to the glass lenses of an optical light microscope. Electron microscopes are used to investigate the ultrastructure of a wide range of biological and inorganic specimens including microorganisms, cells, large molecules, biopsy samples, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David D
David (; , "beloved one") (traditional spelling), , ''Dāwūd''; grc-koi, Δαυΐδ, Dauíd; la, Davidus, David; gez , ዳዊት, ''Dawit''; xcl, Դաւիթ, ''Dawitʿ''; cu, Давíдъ, ''Davidŭ''; possibly meaning "beloved one". was, according to the Hebrew Bible, the third king of the United Kingdom of Israel. In the Books of Samuel, he is described as a young shepherd and harpist who gains fame by slaying Goliath, a champion of the Philistines, in southern Canaan. David becomes a favourite of Saul, the first king of Israel; he also forges a notably close friendship with Jonathan, a son of Saul. However, under the paranoia that David is seeking to usurp the throne, Saul attempts to kill David, forcing the latter to go into hiding and effectively operate as a fugitive for several years. After Saul and Jonathan are both killed in battle against the Philistines, a 30-year-old David is anointed king over all of Israel and Judah. Following his rise to power, D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Standard Model
The Standard Model of particle physics is the theory describing three of the four known fundamental forces ( electromagnetic, weak and strong interactions - excluding gravity) in the universe and classifying all known elementary particles. It was developed in stages throughout the latter half of the 20th century, through the work of many scientists worldwide, with the current formulation being finalized in the mid-1970s upon experimental confirmation of the existence of quarks. Since then, proof of the top quark (1995), the tau neutrino (2000), and the Higgs boson (2012) have added further credence to the Standard Model. In addition, the Standard Model has predicted various properties of weak neutral currents and the W and Z bosons with great accuracy. Although the Standard Model is believed to be theoretically self-consistent and has demonstrated huge successes in providing experimental predictions, it leaves some phenomena unexplained. It falls short of being a com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
