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Gero Hütter
Gero Hütter (born 18 December 1968) is a German hematologist. Hütter and his medical team transplanted bone marrow deficient in a key HIV receptor to a leukemia patient, Timothy Ray Brown, who was also infected with human immunodeficiency virus (HIV). Subsequently, the patient's circulating HIV dropped to undetectable levels. The case was widely reported in the media, and Hütter was named one of the "Berliners of the year" for 2008 by the ''Berliner Morgenpost'', a Berlin newspaper. HIV treatment In 2009, Hütter, Eckhard Thiel and others from the Charité Hospital in Berlin, Germany, published a report on the case in the ''New England Journal of Medicine''. Their patient Timothy Ray Brown, a US citizen born in Seattle, Washington, and living in Berlin, had both acute myelogenous leukemia (AML) and HIV. The physicians found a bone marrow donor with a CCR5-Δ32 mutation in both genomic copies of a gene encoding a cell-surface chemokine receptor called CCR5. Because "most o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Germany
Germany, officially the Federal Republic of Germany, is a country in Central Europe. It lies between the Baltic Sea and the North Sea to the north and the Alps to the south. Its sixteen States of Germany, constituent states have a total population of over 84 million in an area of , making it the most populous member state of the European Union. It borders Denmark to the north, Poland and the Czech Republic to the east, Austria and Switzerland to the south, and France, Luxembourg, Belgium, and the Netherlands to the west. The Capital of Germany, nation's capital and List of cities in Germany by population, most populous city is Berlin and its main financial centre is Frankfurt; the largest urban area is the Ruhr. Settlement in the territory of modern Germany began in the Lower Paleolithic, with various tribes inhabiting it from the Neolithic onward, chiefly the Celts. Various Germanic peoples, Germanic tribes have inhabited the northern parts of modern Germany since classical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Macrophage
Macrophages (; abbreviated MPhi, φ, MΦ or MP) are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris and foreign substances, which do not have proteins that are specific to healthy body cells on their surface. This self-protection method can be contrasted with that employed by Natural killer cell, Natural Killer cells. This process of engulfment and digestion is called phagocytosis; it acts to defend the host against infection and injury. Macrophages are found in essentially all tissues, where they patrol for potential pathogens by amoeboid movement. They take various forms (with various names) throughout the body (e.g., histiocytes, Kupffer cells, alveolar macrophages, microglia, and others), but all are part of the mononuclear phagocyte system. Besides phagocytosis, they play a critical role in nonspecific defense (innate immunity) and also help initiate specific defense mechanisms (adapti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1968 Births
Events January–February * January 1968, January – The I'm Backing Britain, I'm Backing Britain campaign starts spontaneously. * January 5 – Prague Spring: Alexander Dubček is chosen as leader of the Communist Party of Czechoslovakia. * January 10 – John Gorton is sworn in as 19th Prime Minister of Australia, taking over from John McEwen after being 1968 Liberal Party of Australia leadership election, elected leader of the Liberal Party of Australia, Liberal Party the previous day, following the disappearance of Harold Holt. Gorton becomes the only Australian Senate, Senator to become Prime Minister, though he immediately transfers to the Australian House of Representatives, House of Representatives through the 1968 Higgins by-election in Holt's vacant seat. * January 15 – The 1968 Belice earthquake in Sicily kills 380 and injures around 1,000. * January 21 ** Vietnam War: Battle of Khe Sanh – One of the most publicized and controversial battles of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Medical Researchers
German(s) may refer to: * Germany, the country of the Germans and German things **Germania (Roman era) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizenship in Germany, see also German nationality law **Germanic peoples (Roman era) * German diaspora * German language * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
HIV/AIDS Researchers
The human immunodeficiency virus (HIV) is a retrovirus that attacks the immune system. Without treatment, it can lead to a spectrum of conditions including acquired immunodeficiency syndrome (AIDS). It is a preventable disease. It can be managed with treatment and become a manageable chronic health condition. While there is no cure or vaccine for HIV, antiretroviral treatment can slow the course of the disease, and if used before significant disease progression, can extend the life expectancy of someone living with HIV to a nearly standard level. An HIV-positive person on treatment can expect to live a normal life, and die with the virus, not of it. Effective treatment for HIV-positive people (people living with HIV) involves a life-long regimen of medicine to suppress the virus, making the viral load undetectable. Treatment is recommended as soon as the diagnosis is made. An HIV-positive person who has an undetectable viral load as a result of long-term treatment ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Hematologists
German(s) may refer to: * Germany, the country of the Germans and German things **Germania (Roman era) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizenship in Germany, see also German nationality law **Germanic peoples (Roman era) *German diaspora * German language * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (disambiguati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Therapy
Gene therapy is Health technology, medical technology that aims to produce a therapeutic effect through the manipulation of gene expression or through altering the biological properties of living cells. The first attempt at modifying human DNA was performed in 1980, by Martin Cline, but the first successful nuclear gene transfer in humans, approved by the National Institutes of Health, was performed in May 1989. The first therapeutic use of gene transfer as well as the first direct insertion of human DNA into the nuclear genome was performed by French Anderson in a trial starting in September 1990. Between 1989 and December 2018, over 2,900 clinical trials were conducted, with more than half of them in Phases of clinical research, phase I. In 2003, Gendicine became the first gene therapy to receive regulatory approval. Since that time, further gene therapy drugs were approved, such as alipogene tiparvovec (2012), Strimvelis (2016), tisagenlecleucel (2017), voretigene neparvovec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ross Mirkarimi
Rostam Mirkarimi (born 1961) is an American politician and the former sheriff of San Francisco. Prior to being sheriff, he served on the San Francisco Board of Supervisors, where he represented District 5. Mirkarimi is a co-founder of the Green Party of California. Elected as a supervisor, Mirkarimi received national attention in 2007 when he introduced the first legislation prohibiting the use of non-biodegradable plastic bags by large supermarkets and drugstores, making San Francisco the first city to do so. In March 2010, Mirkarimi became a Democrat and he was elected sheriff in November 2011. He served from January to March 2012, at which time he was charged with domestic violence battery, child endangerment, and dissuading a witness in connection with a December 31, 2011 New Year's Eve altercation with his wife, and he was suspended from office pending an ethics investigation.Richmond, Josh (January 13, 2012"San Francisco sheriff Ross Mirkarimi to face misdemeanor cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Scientific World Journal
''The Scientific World Journal'' (formerly, ''The ScientificWorldJournal'') is a peer-reviewed scientific journal covering fields in the life sciences ranging from biomedicine to environmental sciences. It was established in 2001 and is published by Hindawi Publishing Corporation. The journal was delisted in the 2015 ''Journal Citation Reports'' (thus not receiving an impact factor) because of "anomalous citation patterns". Publication history The journal was established in 2001 and is published online and in print. From 2001 to 2011, the managing editor was Graham Lees. In 2011, the journal was acquired by Hindawi Publishing Corporation and converted to open access and to a model without an editor-in-chief. According to Institute for Scientific Information counts, the number of published items in the journal grew steadily from 141 to 227 articles per year between 2008 and 2011 and then increased over fivefold to 1,149 articles in 2011. Organization The journal was divided in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood (journal)
''Blood'' is a peer-reviewed medical journal published by the American Society of Hematology. It was established by William Dameshek in 1946. The journal changed from semimonthly (24 times annually) to weekly publication at the start of 2009. It covers clinical and basic research in all areas of hematology, including disorders of leukocytes, both benign and malignant, erythrocytes, platelets, hemostatic mechanisms, vascular biology, immunology, and hematologic oncology. Abstracting and indexing ''Blood'' is indexed and abstracted by: According to the ''Journal Citation Reports'', the journal has a 2023 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 21.1, and has a Journal Impact Factor rank of 2/97 in the Hematology category. References External l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jay Levy
Jay A. Levy (born November 21, 1938) is an American AIDS and cancer research physician. He is a professor of medicine with specialties in virology and immunology at the University of California, San Francisco (UCSF). Biography Levy was born in Wilmington, Delaware, with his twin brother, Stuart B. Levy. Levy received his B.A. degree with high honors from Wesleyan University (Connecticut) in 1960 and subsequently his M.D. from the College of Physicians and Surgeons at Columbia University in 1965. He conducted research for a year on regeneration in planaria at the Université de Paris (Paris, France) on Fulbright and French government fellowships. From 1961 to 1963, he was a Fellow in the School of International and Public Affairs, Columbia University, New York. He completed his internship and residency at the University of Pennsylvania Medical Center (Philadelphia) from 1965 to 1967. Levy was a staff associate at the National Cancer Institute (Bethesda MD) at the National ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
West Nile Virus
West Nile virus (WNV) is a single-stranded RNA virus that causes West Nile fever. It is a member of the family ''Flaviviridae'', from the genus ''Flavivirus'', which also contains the Zika virus, dengue virus, and yellow fever virus. The virus is primarily transmitted by mosquitoes, mostly species of ''Culex''. The primary host (biology), hosts of WNV are birds, so that the virus remains within a "bird–mosquito–bird" Transmission (medicine), transmission cycle. The virus is genetically related to the Japanese encephalitis family of viruses. Humans and horses both exhibit disease symptoms from the virus, and symptoms rarely occur in other animals. West Nile virus was not named directly after the Nile River, but rather, after the West_Nile_sub-region, West Nile district of Uganda where the virus was first isolated in 1937. Structure Like most other flaviviruses, WNV is an Viral envelope, enveloped virus with icosahedral symmetry. Electron microscope studies reveal a 45–5 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
