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Ficin
Ficain also known as ficin, debricin, or higueroxyl delabarre () is a proteolytic enzyme extracted from the latex sap from the stems, leaves, and unripe fruit of the American wild fig tree ''Ficus insipida''. Ficain was originally called ficin, and ficin was originally a mixture of closely related cysteine endopeptidases produced from any species of the genus ''Ficus'', before the terminology was restricted to a specific cysteine endopeptidase enzyme from a specific species. Cysteine endopeptidases are a group of enzymes that also include the more distantly related papain derived from papaya latex, bromelase (bromelain) extracted from pineapple stem, calpain, caspases, cathepsin B, and chymopapain. Cysteine endopeptidases with similar properties known generically as ficins are present in other members of the genus ''Ficus'', and many species appear to contain multiple types of these enzymes. Somewhat confusingly, the terms ficain and ficin are often treated as synonyms. Ficain is ...
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Ficus Insipida
''Ficus insipida'' is a common tropical tree in the fig genus of the family Moraceae growing in forest habitats along rivers. It ranges from Mexico to northern South America. Taxonomy The tree was described in 1806 under the scientific name ''Ficus insipida'' (literally "insipid fig") by Carl Ludwig Willdenow, having studied the herbarium specimens collected in Caracas by the gardener Franz Bredemeyer in the 1780s during the . Willdenow reports its fruit are tasteless. Incongruously, among the many species of figs to grow in the region, this species is in fact recognisable by its large and sweet figs (when ripe). In the 1960 ''Flora of Panama'', Gordon P. DeWolf Jr. lumped the species ''F. adhatodifolia'' and ''F. crassiuscula'' as synonyms of ''F. insipida'', but his taxonomic interpretation was not followed by subsequent authorities. ''Ficus'' expert Cees Berg distinguished two allopatric or almost allopatric subspecies in 1984: * ''Ficus insipida'' subsp. ''insip ...
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Ficus Glabrata
''Ficus insipida'' is a common tropical tree in the fig genus of the family Moraceae growing in forest habitats along rivers. It ranges from Mexico to northern South America. Taxonomy The tree was described in 1806 under the scientific name ''Ficus insipida'' (literally "insipid fig") by Carl Ludwig Willdenow, having studied the herbarium specimens collected in Caracas by the gardener Franz Bredemeyer in the 1780s during the . Willdenow reports its fruit are tasteless. Incongruously, among the many species of figs to grow in the region, this species is in fact recognisable by its large and sweet figs (when ripe). In the 1960 ''Flora of Panama'', Gordon P. DeWolf Jr. lumped the species ''F. adhatodifolia'' and ''F. crassiuscula'' as synonyms of ''F. insipida'', but his taxonomic interpretation was not followed by subsequent authorities. ''Ficus'' expert Cees Berg distinguished two allopatric or almost allopatric subspecies in 1984: * ''Ficus insipida'' subsp. ''insipida'' ...
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Synonym (taxonomy)
The Botanical and Zoological Codes of nomenclature treat the concept of synonymy differently. * In botanical nomenclature, a synonym is a scientific name that applies to a taxon that (now) goes by a different scientific name. For example, Linnaeus was the first to give a scientific name (under the currently used system of scientific nomenclature) to the Norway spruce, which he called ''Pinus abies''. This name is no longer in use, so it is now a synonym of the current scientific name, ''Picea abies''. * In zoology, moving a species from one genus to another results in a different binomen, but the name is considered an alternative combination rather than a synonym. The concept of synonymy in zoology is reserved for two names at the same rank that refers to a taxon at that rank - for example, the name ''Papilio prorsa'' Linnaeus, 1758 is a junior synonym of ''Papilio levana'' Linnaeus, 1758, being names for different seasonal forms of the species now referred to as ''Araschnia le ...
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Psoralen
Psoralen (also called psoralene) is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins. It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone. Psoralen occurs naturally in the seeds of ''Psoralea corylifolia'', as well as in the common fig, celery, parsley, West Indian satinwood, and in all citrus fruits. It is widely used in PUVA (psoralen + UVA) treatment for psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma; these applications are typically through the use of medications such as Methoxsalen. Many furanocoumarins are extremely toxic to fish, and some are deposited in streams in Indonesia to catch fish. Uses Psoralen is a mutagen, and is used for this purpose in molecular biology research. Psoralen intercalates into DNA and on exposure to ultraviolet (UVA) radiation can form monoadducts and covalent interstrand cross-links (ICL) w ...
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Bromelain
Bromelain is an enzyme extract derived from the stems of pineapples, although it exists in all parts of the fresh pineapple. The extract has a history of folk medicine use. As an ingredient, it is used in cosmetics, as a topical medication, and as a meat tenderizer. The term "bromelain" may refer to either of two protease enzymes extracted from the plants of the family Bromeliaceae, or it may refer to a combination of those enzymes along with other compounds produced in an extract. Bromelain enzymes are called ''fruit bromelain'' and ''stem bromelain''. Although tested in a variety of folk medicine and research models for its possible efficacy against diseases, bromelain has only one approved clinical application issued in 2012 by the European Medicines Agency a topical medication called ''NexoBrid'', used to remove dead tissue in severe skin burns. Extract components Bromelain extract is a mixture of protein-digesting (proteolytic) enzymes and several other substances in smal ...
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Phytophotodermatitis
Phytophotodermatitis, also known as berloque dermatitis or margarita photodermatitis, is a cutaneous phototoxic inflammatory reaction resulting from contact with a light-sensitizing botanical agent followed by exposure to ultraviolet light (from the sun, for instance). Symptoms include erythema, edema, blisters (Skin condition#Vesicle, vesicles and/or Skin condition#Bulla, bullae), and delayed hyperpigmentation. Heat and moisture tend to exacerbate the reaction. A reaction may be elicited in any person who has been exposed to adequate amounts of both a photosensitizing, photosensitizer and ultraviolet light. Phytophotodermatitis is not an Immunology, immunologic response; no prior exposure to the photosensitizing agent is required. The photosensitizing substances found in phototoxic plants belong to a class of chemical compounds called the furanocoumarins, which are activated by long-wavelength ultraviolet (UVA) light. The most toxic of these organic compounds are the linear furan ...
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Furanocoumarin
The furanocoumarins, or furocoumarins, are a class of organic chemical compounds produced by a variety of plants. Most of the plant species found to contain furanocoumarins belong to a handful of plant families. The families Apiaceae and Rutaceae include the largest numbers of plant species that contain furanocoumarins. The families Moraceae and Fabaceae include a few widely distributed plant species that contain furanocoumarins. Generally furanocoumarins are most abundant in plants that have flowered and in ripe seeds and fruits. (An exception is the common fig where furanocoumarins are found chiefly in the milky sap of the leaves and shoots but not the fruits. Cited in McGovern and Barkley 2000, section&nbsPhytophotodermatitis) During the early stages of plant growth, their presence is not easily detected. Structure The chemical structure of furanocoumarins consists of a furan ring fused with a coumarin. The furan ring may be fused in various ways producing several differen ...
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PUVA Therapy
PUVA (psoralen and UVA) is an ultraviolet light therapy treatment for skin diseases: eczema, psoriasis, graft-versus-host disease, vitiligo, mycosis fungoides, large plaque parapsoriasis, and cutaneous T-cell lymphoma, using the sensitizing effects of the drug psoralen. The psoralen is applied or taken orally to sensitize the skin, then the skin is exposed to UVA. Photodynamic therapy is the general use of nontoxic light-sensitive compounds that are exposed selectively to light, whereupon they become toxic to targeted malignant and other diseased cells. Still, PUVA therapy is often classified as a separate technique from photodynamic therapy. Procedure Psoralens are materials that make the skin more sensitive to UV light. They are photosensitizing agents found in plants naturally and manufactured synthetically. Psoralens are taken as pills (systemically) or can be applied directly to the skin, by soaking the skin in a solution that contains the psoralens. They allow UVA energy to ...
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Arteries
An artery (plural arteries) () is a blood vessel in humans and most animals that takes blood away from the heart to one or more parts of the body (tissues, lungs, brain etc.). Most arteries carry oxygenated blood; the two exceptions are the pulmonary and the umbilical arteries, which carry deoxygenated blood to the organs that oxygenate it (lungs and placenta, respectively). The effective arterial blood volume is that extracellular fluid which fills the arterial system. The arteries are part of the circulatory system, that is responsible for the delivery of oxygen and nutrients to all cells, as well as the removal of carbon dioxide and waste products, the maintenance of optimum blood pH, and the circulation of proteins and cells of the immune system. Arteries contrast with veins, which carry blood back towards the heart. Structure The anatomy of arteries can be separated into gross anatomy, at the macroscopic level, and microanatomy, which must be studied with a microscop ...
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Catgut Suture
Catgut suture is a type of surgical suture that is naturally degraded by the body's own proteolytic enzymes. Absorption is complete by 90 days, and full tensile strength remains for at least 7 days. This eventual disintegration makes it good for use in rapidly healing tissues and in internal structures that cannot be re-accessed for suture removal. Catgut suture has high knot-pull tensile strength and good knot security due to special excellent handling features. It is used for all surgical procedures including general closure, ophthalmic, orthopedics, obstetrics/gynecology and gastrointestinal surgery. It is absorbed faster in patients with cancer, anemia, and malnutrition. It also absorbed faster when used in the mouth and the vagina, due to the presence of microorganisms. Catgut has largely been replaced by synthetic absorbable polymers such as Vicryl and polydioxanone. It is not used at all for human surgery in some countries. In Europe and Japan, gut sutures have been banned ...
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Cultivar
A cultivar is a type of cultivated plant that people have selected for desired traits and when propagated retain those traits. Methods used to propagate cultivars include: division, root and stem cuttings, offsets, grafting, tissue culture, or carefully controlled seed production. Most cultivars arise from purposeful human manipulation, but some originate from wild plants that have distinctive characteristics. Cultivar names are chosen according to rules of the International Code of Nomenclature for Cultivated Plants (ICNCP), and not all cultivated plants qualify as cultivars. Horticulturists generally believe the word ''cultivar''''Cultivar'' () has two meanings, as explained in ''Formal definition'': it is a classification category and a taxonomic unit within the category. When referring to a taxon, the word does not apply to an individual plant but to all plants that share the unique characteristics that define the cultivar. was coined as a term meaning "cultivated variety ...
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