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François Jacob
François Jacob (; 17 June 1920 – 19 April 2013) was a French biologist who, together with Jacques Monod, originated the idea that control of enzyme levels in all cells occurs through regulation of transcription. He shared the 1965 Nobel Prize in Medicine with Jacques Monod and André Lwoff. Early years Jacob was born the only child of Simon, a merchant, and Thérèse (Franck) Jacob, in Nancy, France. An inquisitive child, he learned to read at a young age. Albert Franck, Jacob's maternal grandfather, a four-star general, was Jacob's childhood role model. At seven he entered the Lycée Carnot, where he was schooled for the next ten years; in his autobiography, he describes his impression of it: "a cage". He was antagonized by rightist youth at the Lycée Carnot around 1934. He describes his father as a "conformist in religion", while his mother and other family members important in his childhood were secular Jews; shortly after his bar mitzvah, he became an athe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nancy, France
Nancy is the Prefectures in France, prefecture of the northeastern Departments of France, French department of Meurthe-et-Moselle. It was the capital of the Duchy of Lorraine, which was Lorraine and Barrois, annexed by France under King Louis XV in 1766 and replaced by a Provinces of France, province, with Nancy maintained as capital. Following its rise to prominence in the Age of Enlightenment, it was nicknamed the "capital of Eastern France" in the late 19th century. The metropolitan area of Nancy had a population of 508,793 inhabitants as of 2021, making it the 16th-largest functional area (France), functional urban area in France and Lorraine's largest. The population of the city of Nancy proper is 104,387 (2022). The motto of the city is —a reference to the thistle, which is a symbol of Lorraine. Place Stanislas, a large square built between 1752 and 1756 by architect Emmanuel Héré under the direction of Stanislaus I of Poland to link the medieval old town of Nancy and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jewish Culture
Jewish culture is the culture of the Jewish people, from its formation in ancient times until the current age. Judaism itself is not simply a faith-based religion, but an orthopraxy and Ethnoreligious group, ethnoreligion, pertaining to deed, practice, and identity. Jewish culture covers many aspects, including religion and worldviews, literature, media, and cinema, Visual arts in Israel, art and architecture, cuisine and Jewish religious clothing, traditional dress, attitudes to gender, marriage, family, social customs and lifestyles, music and dance. Some elements of Jewish culture come from within Judaism, others from the interaction of Jews with host populations, and others still from the inner social and cultural dynamics of the community. Before the 18th century, religion dominated virtually all aspects of Jewish life, and infused culture. Since the advent of Jewish secularism, secularization, wholly Jewish secularism, secular Jewish culture emerged likewise. History T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcriptional Regulation
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA ( transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in multicellular eukaryotes, as studied in evolutionary developmental biology. The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Expression
Gene expression is the process (including its Regulation of gene expression, regulation) by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, proteins or non-coding RNA, and ultimately affect a phenotype. These products are often proteins, but in non-protein-coding genes such as Transfer RNA, transfer RNA (tRNA) and Small nuclear RNA, small nuclear RNA (snRNA), the product is a functional List of RNAs, non-coding RNA. The process of gene expression is used by all known life—eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and viruses—to generate the macromolecule, macromolecular machinery for life. In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, ''i.e.'' observable trait. The genetic information stored in DNA represents the genotype, whereas the phenotype results from the "interpretation" of that informati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bacteriology
Bacteriology is the branch and specialty of biology that studies the Morphology (biology), morphology, ecology, genetics and biochemistry of bacteria as well as many other aspects related to them. This subdivision of microbiology involves the identification, classification, and characterization of bacterial species. Because of the similarity of thinking and working with microorganisms other than bacteria, such as protozoa, fungi, and non-microorganism viruses, there has been a tendency for the field of bacteriology to extend as microbiology. The terms were formerly often used interchangeably. However, bacteriology can be classified as a distinct science. Overview Definition Bacteriology is the study of bacteria and their relation to medicine. Bacteriology evolved from physicians needing to apply the Germ theory of disease, germ theory to address the concerns relating to disease spreading in hospitals the 19th century. Identification and characterizing of bacteria being associ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tyrothricin
Tyrothricin is an antibiotic mixture which was isolated from ''Brevibacillus brevis'' by Rene Dubos in the late 1930s. It was later shown by Dubos and Rollin Hotchkiss to be a mixture of two different antibiotics: gramicidin and tyrocidine. Both gramicidin and tyrocidine are short polypeptides which disrupt the cell membranes of some, primarily Gram-positive, bacteria. Tyrothricin and its component antibiotics are too toxic to be taken internally but are sometimes used as topical antibiotics. Tyrothricin, and its component antibiotics, belongs to the pharmacologically related group of polypeptide antibiotic compounds including colistin, polymyxin B, and bacitracin Bacitracin is a polypeptide antibiotic. It is a mixture of related cyclic peptides produced by '' Bacillus licheniformis'' bacteria, that was first isolated from the variety "Tracy I" ( ATCC 10716) in 1945. These peptides disrupt Gram-positiv .... There is no cross-resistance to these three agents. Reference ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Croix De Guerre 1939–1945
Croix (French for "cross") may refer to: Belgium * Croix-lez-Rouveroy, a village in municipality of Estinnes in the province of Hainaut France * Croix, Nord, in the Nord department * Croix, Territoire de Belfort, in the Territoire de Belfort department * Croix-Caluyau, in the Nord department * Croix-Chapeau, in the Charente-Maritime department * Croix-en-Ternois, in the Pas-de-Calais department * Croix-Fonsomme, in the Aisne department * Croix-Mare, in the Seine-Maritime department * Croix-Moligneaux, in the Somme department * Canton of Croix, administrative division of the Nord department, northern France People * Croix Bethune Croix Collette Bethune ( ; born March 14, 2001) is an American professional association football, soccer player who plays as an attacking midfielder for the Washington Spirit of the National Women's Soccer League (NWSL) and the United States wom ... (born 2001), American soccer player See also * Croix Scaille, a hill plateau in the Ard ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Légion D'honneur
The National Order of the Legion of Honour ( ), formerly the Imperial Order of the Legion of Honour (), is the highest and most prestigious French national order of merit, both military and Civil society, civil. Currently consisting of five classes, it was originally established in 1802 by Napoleon, Napoleon Bonaparte, and it has been retained (with occasional slight alterations) by all later French governments and regimes. The order's motto is ' ("Honour and Fatherland"); its Seat (legal entity), seat is the Palais de la Légion d'Honneur next to the Musée d'Orsay, on the left bank of the Seine in Paris. Since 1 February 2023, the Order's grand chancellor has been retired General François Lecointre, who succeeded fellow retired General Benoît Puga in office. The order is divided into five degrees of increasing distinction: ' (Knight), ' (Officer), ' (Commander (order), Commander), ' (Grand Officer) and ' (Grand Cross). History Consulate During the French Revolution, all ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ordre De La Libération
The Order of Liberation (, ) is a French Order which was awarded to heroes of the Liberation of France during World War II. It is a worn by recipients only before the ''Légion d’Honneur'' (Legion of Honour). In the official portrait of General de Gaulle as President, he wore the grand collar of the Order and not the grand collar of the Légion d'Honneur, hence signifying the preeminence of the Order ahead of the Légion d'Honneur. Individuals (nationals and foreigners such as the Sultan of Morocco), cities and military units were awarded it upon the sole decision of De Gaulle for feats of heroism in the French Resistance, the Forces Françaises Libres and the Armée d'Afrique; and only for their deeds during World War II. To date it is the only French royal, imperial or republican chivalry order that became extinct with the death of its last member. The youngest Companion, assassinated by the Germans, was only 16 years of age. Another decoration, the '' Médaille de la R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Liberation Of France
The liberation of France () in the Second World War was accomplished through diplomacy, politics and the combined military efforts of the Allied Powers, Free French forces in London and Africa, as well as the French Resistance. Nazi Germany invaded France in May 1940. Their rapid advance through the almost undefended Ardennes caused a crisis in the French government; the French Third Republic dissolved itself in July, and handed over absolute power to Marshal Philippe Pétain, an elderly hero of World War I. Pétain signed an armistice with Germany with the north and west of France under German military occupation. Pétain, charged with calling a Constitutional Authority, instead established an authoritarian government in the spa town of Vichy, in the southern ''zone libre'' ("free zone"). Though nominally independent, Vichy France became a collaborationist regime and was little more than a Nazi client state that actively participated in Jewish deportations and aided German ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2nd Armored Division (France)
The French 2nd Armored Division (), commanded by General Philippe Leclerc de Hauteclocque, Philippe Leclerc, fought during the final phases of World War II in the Western Front (World War II), Western Front for the liberation of France. The division was formed around a core of units that had fought in the North African campaign, and re-organized into a light armored division in 1943. The division embarked in April 1944 and shipped to various ports in Britain. On 29 July 1944, bound for France, the division embarked at Southampton. During combat in 1944, the division liberated Paris, defeated a Panzer brigade during the armored clashes in Lorraine, forced the Saverne Gap and liberated Strasbourg. After taking part in the Battle of the Colmar Pocket, the division was moved west and assaulted the German-held Atlantic port of Royan, before recrossing France in April 1945 and participating in the final fighting in southern Germany, even going first into Hitler's "Eagle's Nest" (America ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
