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F Wave
In neuroscience, an F wave is one of several motor responses which may follow the direct motor response (M) evoked by electrical stimulation of peripheral motor or mixed (sensory and motor) nerves. F-waves are the second of two late voltage changes observed after stimulation is applied to the skin surface above the distal region of a nerve, in addition to the H-reflex (Hoffman's Reflex) which is a muscle reaction in response to electrical stimulation of innervating sensory fibers. Traversal of F-waves along the entire length of peripheral nerves between the spinal cord and muscle, allows for assessment of motor nerve conduction between distal stimulation sites in the arm and leg, and related motoneurons (MN's) in the cervical and lumbosacral cord. F-waves are able to assess both afferent and efferent loops of the alpha motor neuron in its entirety. As such, various properties of F-wave motor nerve conduction are analyzed in nerve conduction studies (NCS), and often used to asses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions, and its disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. Hist ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antidromic
An antidromic impulse in an axon refers to conduction opposite of the normal ( orthodromic) direction. That is, it refers to conduction along the axon away from the axon terminal(s) and towards the soma. For most neurons, their dendrites, soma, or axons are depolarized forming an action potential that moves from the starting point of the depolarization (near the cell body) along the axons of the neuron A neuron (American English), neurone (British English), or nerve cell, is an membrane potential#Cell excitability, excitable cell (biology), cell that fires electric signals called action potentials across a neural network (biology), neural net ... ( orthodromic). Antidromic activation is often induced experimentally by direct electrical stimulation of a presumed target structure. Antidromic activation is often used in a laboratory setting to confirm that a neuron being recorded from projects to the structure of interest. References Neurophysiology {{Neuroscience-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
H Reflex
The H-reflex (or Hoffmann's reflex) is a reflectory reaction of muscles after electrical stimulation of sensory fibers ( Ia afferents stemming from muscle spindles) in their innervating nerves (for example, those located behind the knee). The H-reflex test is performed using an electric stimulator, which gives usually a square-wave current of short duration and small amplitude (higher stimulations might involve alpha fibers, causing an F-wave, compromising the results), and an EMG set, to record the muscle response. That response is usually a clear wave, called H-wave, 28-35 ms after the stimulus, not to be confused with an F-wave. An M-wave, an early response, occurs 3-6 ms after the onset of stimulation. The H and F-waves are later responses. As the stimulus increases, the amplitude of the F-wave increases only slightly, and the H-wave decreases, and at supramaximal stimulus, the H-wave will disappear. The M-wave does the opposite of the H-wave. As the stimulus increases ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guillain–Barré Syndrome
Guillain–Barré syndrome (GBS) is a rapid-onset Paralysis, muscle weakness caused by the immune system damaging the peripheral nervous system. Typically, both sides of the body are involved, and the initial symptoms are changes in sensation or pain often in the back along with muscle weakness, beginning in the feet and hands, often spreading to the arms and upper body. The symptoms may develop over hours to a few weeks. During the acute phase, the disorder can be life-threatening, with about 15% of people developing respiratory system, respiratory muscle weakness requiring mechanical ventilation. Some are affected by dysautonomia, changes in the function of the autonomic nervous system, which can lead to dangerous abnormalities in heart rate and blood pressure. Although the cause is unknown, the underlying mechanism involves an autoimmune disorder in which the body's immune system mistakenly attacks the peripheral nerves and damages their myelin insulation. Sometimes this im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Millisecond
A millisecond (from '' milli-'' and second; symbol: ms) is a unit of time in the International System of Units equal to one thousandth (0.001 or 10−3 or 1/1000) of a second or 1000 microseconds. A millisecond is to one second, as one second is to approximately 16.67 minutes. A unit of 10 milliseconds may be called a centisecond, and one of 100 milliseconds a decisecond, but these names are rarely used. To help compare orders of magnitude of different times, this page lists times between 10−3 seconds and 100 seconds (1 millisecond and one second). ''See also'' times of other orders of magnitude. Examples The Apollo Guidance Computer used metric units internally, with centiseconds used for time calculation and measurement. *1 millisecond (1 ms) – cycle time for frequency 1 kHz; duration of light for typical photo flash strobe; time taken for sound wave to travel about 34 cm; repetition interval of GPS C/A PN code *1 millisecond – time taken ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Volt
The volt (symbol: V) is the unit of electric potential, Voltage#Galvani potential vs. electrochemical potential, electric potential difference (voltage), and electromotive force in the International System of Units, International System of Units (SI). Definition One volt is defined as the electric potential between two points of a electrical conductor, conducting wire when an electric current of one ampere dissipates one watt of power (physics), power between those points. It can be expressed in terms of SI base units (metre, m, kilogram, kg, second, s, and ampere, A) as : \text = \frac = \frac = \frac = \text\text^2\text^. Equivalently, it is the potential difference between two points that will impart one joule of energy per coulomb of charge that passes through it. It can be expressed in terms of SI base units (metre, m, kilogram, kg, second, s, and ampere, A) as : \text = \frac = \frac = \frac = \text\text^2\text^. It can also be expressed as amperes times ohms (curre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Renshaw Cell
Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord, and are associated in two ways with an alpha motor neuron. * They receive an excitatory collateral from the alpha neuron's axon as they emerge from the motor root, and are thus "kept informed" of how vigorously that neuron is firing. * They send an inhibitory axon to synapse with the cell body of the initial alpha neuron and/or an alpha motor neuron of the same motor pool. In this way, the Renshaw cell action represents a negative feedback mechanism. A Renshaw cell may be supplied by more than one alpha motor neuron collateral and it may synapse on multiple motor neurons. Function Although during embryonic development the Renshaw cells lack synapses from the dorsal root, prenatal and postnatal stages show the development of dorsal root originating synapses, which are functional and stimulate action potentials. But these decrease during development while acetylcholine motor axons begin to syn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyperpolarization (biology)
Hyperpolarization is a change in a cell's membrane potential that makes it more negative. Cells typically have a negative resting potential, with neuronal action potentials depolarizing the membrane. When the resting membrane potential is made more negative, it increases the minimum stimulus needed to surpass the needed threshold. Neurons naturally become hyperpolarized at the end of an action potential, which is often referred to as the relative refractory period. Relative refractory periods typically last 2 milliseconds, during which a stronger stimulus is needed to trigger another action potential. Cells can also become hyperpolarized depending on channels and receptors present on the membrane, which can have an inhibitory effect. Hyperpolarization is often caused by efflux of K+ (a cation) through K+ channels, or influx of Cl– (an anion) through Cl– channels. On the other hand, influx of cations, e.g. Na+ through Na+ channels or Ca2+ through Ca2+ cha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anterior Horn Of Spinal Cord
The grey columns are three regions of the somewhat ridge-shaped mass of grey matter in the spinal cord. These regions present as three columns: the anterior grey column, the posterior grey column, and the lateral grey column, all of which are visible in cross-section of the spinal cord. The anterior grey column is made up of alpha motor neurons, gamma motor neurons, and small neurons thought to be interneurons. It affects the Skeletal muscle, skeletal muscles. The posterior grey column receives several types of sensory information regarding touch and sensation from receptors in the skin, bones, and joints, including Somatosensory system#fine touch, fine touch, proprioception, and Oscillation, vibration. It contains the cell bodies of Second-order neuron, second-order sensory neurons and their synapses with the Pseudounipolar neuron, pseudounipolar First-order neuron, first-order sensory neurons (whose cell bodies are located within the Sensory ganglia, sensory ganglia (a.k.a. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Soma (biology)
In cellular neuroscience, the soma (: somata or somas; ), neurocyton, or cell body is the bulbous, non-process portion of a neuron or other brain cell type, containing the cell nucleus. Although it is often used to refer to neurons, it can also refer to other cell types as well, including astrocytes, oligodendrocytes, and microglia. The part of the soma without the nucleus is called perikaryon (: perikarya). There are many different specialized types of neurons, and their sizes vary from as small as about 5 micrometres to over 10 millimetres for some of the smallest and largest neurons of invertebrates, respectively. The soma of a neuron (i.e., the main part of the neuron in which the dendrites branch off of) contains many organelles, including granules called Nissl granules, which are composed largely of rough endoplasmic reticulum and free polyribosomes. The cell nucleus is a key feature of the soma. The nucleus is the source of most of the RNA that is produced in ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Compound Muscle Action Potential
The compound muscle action potential (CMAP) or compound motor action potential is an electrodiagnostic medicine investigation (electrical study of muscle function). The CMAP idealizes the summation of a group of almost simultaneous action potentials from several muscle fibers in the same area. These are usually evoked by stimulation of the motor nerve. Patients that suffer from critical illness myopathy, which is a frequent cause of weakness seen in patients in hospital intensive care unit An intensive care unit (ICU), also known as an intensive therapy unit or intensive treatment unit (ITU) or critical care unit (CCU), is a special department of a hospital or health care facility that provides intensive care medicine. An inten ...s, have prolonged compound muscle action potential. References Neurophysiology Action potentials {{med-imaging-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
