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Enzo Emanuele
Enzo Emanuele (born June 10, 1977) is an Italian clinical pathologist known for his interdisciplinary research in the field of biological psychology. He has studied the biochemical basis of romantic interpersonal attraction and identified the neurotrophin nerve growth factor (NGF) as a key biochemical mediator of falling in love. The implications of this research have been criticized in the popular press. In 2008, his genetic research, which showed an association between serotonin and dopamine receptor gene polymorphisms and certain love traits, was awarded with the International Zdenek Klein Award for Human Ethology from Charles University in Prague, Czech Republic. Emanuele is also known for his studies on biomarkers of atherosclerosis. On October 3, 2009, Enzo Emanuele was awarded by the Italian Society for the Study of Atherosclerosis (SISA), Lombardy Section, with the Giovanni Galli Prize for his scientific contributions in the field of cardiovascular biomarkers. He gradu ...
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Novara, Italy
Novara (; Novarese: ) is the capital city of the province of Novara in the Piedmont region in northwest Italy, to the west of Milan. With 101,916 inhabitants (on 1 January 2021), it is the second most populous city in Piedmont after Turin. It is an important crossroads for commercial traffic along the routes from Milan to Turin and from Genoa to Switzerland. Novara lies between the streams Agogna and Terdoppio in northeastern Piedmont, from Milan and from Turin. It is only distant from the river Ticino, which marks the border with Lombardy region. History Novara was founded around 89 BC by the Romans, when the local Gauls obtained Roman citizenship. Its name is formed from ''Nov'', meaning "new", and ''Aria'', the name the Cisalpine Gauls used for the surrounding region. Ancient ''Novaria'', which dates to the time of the Ligures and the Celts, was a municipium and was situated on the road from Vercellae (Vercelli) to (Mediolanum) Milan. Its position on perpendicular roads ( ...
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Love Styles
The colour wheel theory of love is an idea created by the Canadian psychologist John Alan Lee that describes six love styles, using several Latin and Greek words for love. First introduced in his book ''Colours of Love: An Exploration of the Ways of Loving'' (1973), Lee defines three primary, three secondary, and nine tertiary love styles, describing them in the traditional colour wheel. The three primary types are called Eros, Ludus, and Storge, and the three secondary types are called Mania, Pragma, and Agape. Eros focuses on the sexual life, Ludus on the playful life, and Storge on the serious life. For the secondary types, Mania (Eros & Ludus) is characterized by obsession and overattachment, Agape (Eros & Storge) by altruism and trust, and Pragma (Ludus & Storge) by realism and practicality. Primary types of love Eros ''Eros'' is the Greek term for romantic, passionate, or sexual love, from which the term ''erotic'' is derived. Lee describes Eros as a passionate phy ...
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Dementia
Dementia is a syndrome associated with many neurodegenerative diseases, characterized by a general decline in cognitive abilities that affects a person's ability to perform activities of daily living, everyday activities. This typically involves problems with memory, thinking, behavior, and motor control. Aside from memory impairment and a thought disorder, disruption in thought patterns, the most common symptoms of dementia include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum (measurement), continuum over several stages. Dementia is a life-limiting condition, having a significant effect on the individual, their caregivers, and their social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning and a greater cognitive decline than might be caused by the normal aging process. Several diseases and injuries to the brain, ...
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Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated blood levels of cholesterol. These lesions may lead to narrowing of the arterial walls due to buildup of atheromatous plaques. At the onset, there are usually no symptoms, but if they develop, symptoms generally begin around middle age. In severe cases, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney disorders, depending on which body part(s) the affected arteries are located in the body. The exact cause of atherosclerosis is unknown and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory biomarkers, high blood pressure, diabetes, smoking (both active and passive smoking), obesity, genetic factors, family history, lifes ...
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RAGE (receptor)
RAGE (receptor (biochemistry), receptor for advanced glycation end-product, advanced glycation end-products), also called AGER, is a 35 kilodalton transmembrane receptor of the immunoglobulin super family which was first characterized in 1992 by Neeper ''et al.'' Its name comes from its ability to bind advanced glycation end-products (advanced glycation endproduct, AGEs), which include chiefly glycoproteins, the glycans of which have been modified non-enzyme, enzymatically through the Maillard reaction. In view of its inflammatory function in innate immunity and its ability to detect a class of ligands through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility group protein B1 (HMGB1). HMGB1 is an intracellular DNA-binding protein important in chromatin remodeling which can be released by necrotic cells passively, and by active secretion from macrophages, natural killer cells ...
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Pavia, Italy
Pavia ( , ; ; ; ; ) is a town and comune of south-western Lombardy, in Northern Italy, south of Milan on the lower Ticino near its confluence with the Po. It has a population of c. 73,086. The city was a major political centre in the medieval period, being the capital of the Ostrogothic Kingdom from 540 to 553, of the Kingdom of the Lombards from 572 to 774, of the Kingdom of Italy from 774 to 1024 and seat of the Visconti court from 1365 to 1413. Pavia is the capital of the fertile province of Pavia, which is known for a variety of agricultural products, including wine, rice, cereals, and dairy products. Although there are a number of industries located in the suburbs, these tend not to disturb the peaceful atmosphere of the town. It is home to the ancient University of Pavia (founded in 1361 and recognized in 2022 by the Times Higher Education among the top 10 in Italy and among the 300 best in the world), which together with the IUSS (Institute for Advanced Studies of Pav ...
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Physician
A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the Medical education, study, Medical diagnosis, diagnosis, prognosis and therapy, treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as Specialty (medicine), specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practitioner, general practice. Medical practice properly requires both a detailed knowledge of the Discipline (academia), academic disciplines, such as anatomy and physiology, pathophysiology, underlying diseases, and their treatment, which is the science of medicine, and a decent Competence (human resources ...
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Prize
A prize is an award to be given to a person or a group of people (such as sporting teams and organizations) to recognize and reward their actions and achievements.Prize
definition 1, The Free Dictionary, Farlex, Inc. Retrieved August 7, 2009.
Official prizes often involve monetary rewards as well as the fame that comes with them. Some prizes are also associated with extravagant awarding ceremonies, such as the Academy Awards. Prizes are also given to publicize noteworthy or exemplary behaviour, and to provide incentives for improved outcomes and competitive efforts. In general, prizes are regarded in a positive light, and their winners are admired. However, many prizes, ...
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Lombardy
The Lombardy Region (; ) is an administrative regions of Italy, region of Italy that covers ; it is located in northern Italy and has a population of about 10 million people, constituting more than one-sixth of Italy's population. Lombardy is located between the Alps mountain range and tributaries of the river Po (river), Po, and includes Milan, its capital, the largest metropolitan area in the country, and among the largest in the EU. Its territory is divided into 1,502 ''comuni'' (the region with the largest number of ''comuni'' in the entire national territory), distributed among twelve administrative subdivisions (eleven Provinces of Italy, provinces plus the Metropolitan City of Milan). The region ranks first in Italy in terms of population, population density, and number of local authorities, while it is fourth in terms of surface area, after Sicily, Piedmont, and Sardinia. It is the second-most populous Region (Europe), region of the European Union (EU), and the List of ...
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Atherosclerosis
Atherosclerosis is a pattern of the disease arteriosclerosis, characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types and is driven by elevated blood levels of cholesterol. These lesions may lead to narrowing of the arterial walls due to buildup of atheromatous plaques. At the onset, there are usually no symptoms, but if they develop, symptoms generally begin around middle age. In severe cases, it can result in coronary artery disease, stroke, peripheral artery disease, or kidney disorders, depending on which body part(s) the affected arteries are located in the body. The exact cause of atherosclerosis is unknown and is proposed to be multifactorial. Risk factors include dyslipidemia, abnormal cholesterol levels, elevated levels of inflammatory biomarkers, high blood pressure, diabetes, smoking (both active and passive smoking), obesity, genetic factors, family history, lifes ...
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Italy
Italy, officially the Italian Republic, is a country in Southern Europe, Southern and Western Europe, Western Europe. It consists of Italian Peninsula, a peninsula that extends into the Mediterranean Sea, with the Alps on its northern land border, as well as List of islands of Italy, nearly 800 islands, notably Sicily and Sardinia. Italy shares land borders with France to the west; Switzerland and Austria to the north; Slovenia to the east; and the two enclaves of Vatican City and San Marino. It is the List of European countries by area, tenth-largest country in Europe by area, covering , and the third-most populous member state of the European Union, with nearly 59 million inhabitants. Italy's capital and List of cities in Italy, largest city is Rome; other major cities include Milan, Naples, Turin, Palermo, Bologna, Florence, Genoa, and Venice. The history of Italy goes back to numerous List of ancient peoples of Italy, Italic peoples—notably including the ancient Romans, ...
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Prague, Czech Republic
Prague ( ; ) is the capital and largest city of the Czech Republic and the historical capital of Bohemia. Prague, located on the Vltava River, has a population of about 1.4 million, while its metropolitan area is home to approximately 2.3 million people. Prague is a historical city with Romanesque, Gothic, Renaissance and Baroque architecture. It was the capital of the Kingdom of Bohemia and residence of several Holy Roman Emperors, most notably Charles IV (r. 1346–1378) and Rudolf II (r. 1575–1611). It was an important city to the Habsburg monarchy and Austria-Hungary. The city played major roles in the Bohemian and the Protestant Reformations, the Thirty Years' War and in 20th-century history as the capital of Czechoslovakia between the World Wars and the post-war Communist era. Prague is home to a number of cultural attractions including Prague Castle, Charles Bridge, Old Town Square with the Prague astronomical clock, the Jewish Quarter, Petř ...
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