David Macht
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David Macht
David Israel Macht (February 14, 1882 – October 14, 1961) was a pharmacologist and Doctor of Hebrew Literature, responsible for many contributions to pharmacology during the first half of the 20th century. Born in Moscow in 1882, Macht moved to Baltimore in 1892, age 10. He was awarded a bachelor's and a medical degree by Johns Hopkins University in 1905, and took postgraduate courses in Berlin, Munich and Vienna. He returned to America in 1909 to join the teaching staff at Johns Hopkins. He rose to the position of assistant professor, lecturing in pharmacology from 1912 to 1932. His grandson, Kenneth Lasson, would later report that at that time Johns Hopkins had a faculty quota limiting the number of Jewish staff that could proceed to full faculty. In 1928 Macht received the first degree of advanced research awarded at Yeshiva University, Yeshiva College, New York, being made Doctor of Rabbinic literature, Hebrew Literature. From 1933 to 1941 he served as visiting professor ...
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David Macht
David Israel Macht (February 14, 1882 – October 14, 1961) was a pharmacologist and Doctor of Hebrew Literature, responsible for many contributions to pharmacology during the first half of the 20th century. Born in Moscow in 1882, Macht moved to Baltimore in 1892, age 10. He was awarded a bachelor's and a medical degree by Johns Hopkins University in 1905, and took postgraduate courses in Berlin, Munich and Vienna. He returned to America in 1909 to join the teaching staff at Johns Hopkins. He rose to the position of assistant professor, lecturing in pharmacology from 1912 to 1932. His grandson, Kenneth Lasson, would later report that at that time Johns Hopkins had a faculty quota limiting the number of Jewish staff that could proceed to full faculty. In 1928 Macht received the first degree of advanced research awarded at Yeshiva University, Yeshiva College, New York, being made Doctor of Rabbinic literature, Hebrew Literature. From 1933 to 1941 he served as visiting professor ...
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Codeine
Codeine is an opiate and prodrug of morphine mainly used to treat pain, coughing, and diarrhea. It is also commonly used as a recreational drug. It is found naturally in the sap of the opium poppy, ''Papaver somniferum''. It is typically used to treat mild to moderate degrees of pain. Greater benefit may occur when combined with paracetamol (acetaminophen) or a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin or ibuprofen. Evidence does not support its use for acute cough suppression in children or adults. In Europe, it is not recommended as a cough medicine in those under 12 years of age. It is generally taken by mouth. It typically starts working after half an hour, with maximum effect at two hours. Its effects last for about four to six hours. Codeine exhibits abuse potential similar to other opioid medications. Common side effects include vomiting, constipation, itchiness, lightheadedness, and drowsiness. Serious side effects may include breathing difficult ...
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Root
In vascular plants, the roots are the organs of a plant that are modified to provide anchorage for the plant and take in water and nutrients into the plant body, which allows plants to grow taller and faster. They are most often below the surface of the soil, but roots can also be aerial or aerating, that is, growing up above the ground or especially above water. Function The major functions of roots are absorption of water, plant nutrition and anchoring of the plant body to the ground. Anatomy Root morphology is divided into four zones: the root cap, the apical meristem, the elongation zone, and the hair. The root cap of new roots helps the root penetrate the soil. These root caps are sloughed off as the root goes deeper creating a slimy surface that provides lubrication. The apical meristem behind the root cap produces new root cells that elongate. Then, root hairs form that absorb water and mineral nutrients from the soil. The first root in seed producing plants is the r ...
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Control Group
In the design of experiments, hypotheses are applied to experimental units in a treatment group. In comparative experiments, members of a control group receive a standard treatment, a placebo, or no treatment at all. There may be more than one treatment group, more than one control group, or both. A placebo control group can be used to support a double-blind study, in which some subjects are given an ineffective treatment (in medical studies typically a sugar pill) to minimize differences in the experiences of subjects in the different groups; this is done in a way that ensures no participant in the experiment (subject or experimenter) knows to which group each subject belongs. In such cases, a third, non-treatment control group can be used to measure the placebo effect directly, as the difference between the responses of placebo subjects and untreated subjects, perhaps paired by age group or other factors (such as being twins). For the conclusions drawn from the results of an e ...
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Lupinus Albus
''Lupinus albus'', commonly known as the white lupin or field lupine, is a member of the genus ''Lupinus'' in the family Fabaceae. It is a traditional pulse cultivated in the Mediterranean region. Description The white lupin is annual, more or less pubescent plant, 30 to 120 cm high, has a wide distribution in the Mediterranean region. White lupine is widely spread as wild plants throughout the southern Balkans, the Italian mainland region of Apulia, the islands of Sicily, Corsica, and Sardinia, and the Aegean Sea, as well as in Lebanon, Israel, Palestine, and western Anatolia. It occurs in meadows, pastures, and grassy slopes, predominantly on sandy and acid soils. It is cultivated over all the Mediterranean region and also in Egypt, Sudan, Ethiopia, Syria, Central and Western Europe, USA and South America, Tropical and Southern Africa, Russia, and Ukraine. The ancient culture of white lupin under the local name "hanchcoly" was practiced until recently in Western Georgi ...
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Phytopharmacology
Phytopharmacology is the study and practice of eradicating plant pathology originated from the ''Verbandes Deutscher Pflanzenärzte'' (1928–1939), (German Plant Physicians Society), headed by Otto Appel, known as the ''Organiser of German Plant Protection'', who initially defined the terminology of ''Phyto-Medicine'' or ''Plant Medicine''. The Deutsche Phytomedizinische Gesellschaft (German Phytomedicine Society) is the German association of phytomedicine practitioners. Academic programs in phytomedicine, such as at the University of Hohenheim The University of Hohenheim (german: Universität Hohenheim) is a campus university located in the south of Stuttgart, Germany. Founded in 1818, it is Stuttgart's oldest university. Its primary areas of specialisation had traditionally been ..., consider the interrelationships between pathogenic microorganisms and crops, disease control methods, and research programs. In 1936, the term ''phytopharmacology'' was used for the field of ...
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Psychopharmacology
Psychopharmacology (from Greek grc, ψῡχή, psȳkhē, breath, life, soul, label=none; grc, φάρμακον, pharmakon, drug, label=none; and grc, -λογία, -logia, label=none) is the scientific study of the effects drugs have on mood, sensation, thinking, behavior, judgment and evaluation, and memory. It is distinguished from neuropsychopharmacology, which emphasizes the correlation between drug-induced changes in the functioning of cells in the nervous system and changes in consciousness and behavior. The field of psychopharmacology studies a wide range of substances with various types of psychoactive properties, focusing primarily on the chemical interactions with the brain. The term "psychopharmacology" was likely first coined by David Macht in 1920. Psychoactive drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and ...
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Venom
Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a stinger, in a process called envenomation. Venom is often distinguished from poison, which is a toxin that is passively delivered by being ingested, inhaled, or absorbed through the skin, and toxungen, which is actively transferred to the external surface of another animal via a physical delivery mechanism. Venom has evolved in terrestrial and marine environments and in a wide variety of animals: both predators and prey, and both vertebrates and invertebrates. Venoms kill through the action of at least four major classes of toxin, namely necrotoxins and cytotoxins, which kill cells; neurotoxins, which affect nervous systems; myotoxins, which damage muscles; and haemotoxins, which disrupt blood clotting. Venomous animals cause tens of thousa ...
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Research
Research is "creativity, creative and systematic work undertaken to increase the stock of knowledge". It involves the collection, organization and analysis of evidence to increase understanding of a topic, characterized by a particular attentiveness to controlling sources of bias and error. These activities are characterized by accounting and controlling for biases. A research project may be an expansion on past work in the field. To test the validity of instruments, procedures, or experiments, research may replicate elements of prior projects or the project as a whole. The primary purposes of basic research (as opposed to applied research) are documentation, Discovery (observation), discovery, interpretation (philosophy), interpretation, and the research and development (R&D) of methods and systems for the advancement of human knowledge. Approaches to research depend on epistemology, epistemologies, which vary considerably both within and between humanities and sciences. ...
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Antibodies
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few vari ...
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Pemphigus
Pemphigus ( or ) is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes. The name is derived from the Greek root ''pemphix'', meaning "pustule". In pemphigus, autoantibodies form against desmoglein, which forms the "glue" that attaches adjacent epidermal cells via attachment points called desmosomes. When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes detached, a phenomenon called acantholysis. This causes blisters that slough off and turn into sores. In some cases, these blisters can cover a large area of the skin. Originally, the cause of this disease was unknown, and "pemphigus" was used to refer to any blistering disease of the skin and mucosa. In 1964, researchers found that the blood of patients with pemphigus contained antibodies to the layers of skin that separate to form the blisters. In 1971, an article investigating the autoimmune nature of this disease was published ...
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