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Daniel Colón-Ramos
Daniel Alfonso Colón-Ramos is the McConnell Duberg Professor of Neuroscience and Cell Biology at Yale University School of Medicine, where his lab studies the cell biology of the synapse during development and learning. He is also the founder of the nonprofit organization Ciencia Puerto Rico (CienciaPR), a collaborative network for people interested in science and Puerto Rico. In 2020, he was named to the National Academy of Medicine. Education & early career Colón-Ramos was born and raised in Puerto Rico, growing up between the towns of Guaynabo and Barranquitas. He studied elementary school in Colegio Mater Salvatoris and high school in Colegio San Ignacio de Loyola. He received his Bachelor of Arts degree from Harvard University in 1998. During his undergraduate career, he pursued research projects, such as studying the use of medicinal plants among indigenous Central American communities with the Smithsonian Tropical Research Institute (STRI). He then worked as a resea ...
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Hato Rey, Puerto Rico
Hato Rey is a former barrio located in the northwest part of the dissolved municipality of Río Piedras, Puerto Rico, Río Piedras. It now stretches over three Barrios of Puerto Rico, barrios, of the municipality of San Juan, Puerto Rico, San Juan, Puerto Rico: Urban landscape Its name means "king's cattle farm" (''w:es:Hato, hato''). In the 18th century, cattle would roam among the sugar cane fields in the area. Its proximity to residential areas such as Old San Juan, San Juan, Río Piedras, Puerto Rico, Río Piedras, Miramar (Santurce), Miramar made it a perfect location from where to produce what its residents would eat. The area also used to be known as ''Las Monjas'' (the nuns) due to a convent that used to be located in the area in the 19th century. The Northern portion of Hato Rey is a startling contrast between blight and poverty and ''Milla de Oro, La Milla de Oro'' (The Golden Mile), a stretch that effectively covers only one mile but that is home to the headquarters ...
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Guaynabo, Puerto Rico
Guaynabo (, ) is a city, suburb of San Juan and municipality in the northern part of Puerto Rico, located in the northern coast of the island, north of Aguas Buenas, south of Cataño, east of Bayamón, and west of San Juan. Guaynabo is spread over 9 barrios and Guaynabo Pueblo (the downtown area and the administrative center of the suburb). Guaynabo is considered, along with its neighbors – San Juan and the municipalities of Bayamón, Carolina, Cataño, Trujillo Alto, and Toa Baja – to be part of the San Juan metropolitan area. It is also part of the larger San Juan-Caguas-Guaynabo Metropolitan Statistical Area, (the largest MSA in Puerto Rico). The municipality has a land area of and a population of 89,780 as of the 2020 census. The municipality is known for being an affluent suburb of San Juan and for its former Irish heritage. The studios of WAPA-TV is located in Guaynabo. History The first European settlement in Puerto Rico, Caparra, was founded in 1508 b ...
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Glia
Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system that do not produce electrical impulses. They maintain homeostasis, form myelin in the peripheral nervous system, and provide support and protection for neurons. In the central nervous system, glial cells include oligodendrocytes, astrocytes, ependymal cells, and microglia, and in the peripheral nervous system they include Schwann cells and satellite cells. Function They have four main functions: *to surround neurons and hold them in place *to supply nutrients and oxygen to neurons *to insulate one neuron from another *to destroy pathogens and remove dead neurons. They also play a role in neurotransmission and synaptic connections, and in physiological processes such as breathing. While glia were thought to outnumber neurons by a ratio of 10:1, recent studies using newer methods and reappraisal of historical quan ...
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Synapse
In the nervous system, a synapse is a structure that permits a neuron (or nerve cell) to pass an electrical or chemical signal to another neuron or to the target effector cell. Synapses are essential to the transmission of nervous impulses from one neuron to another. Neurons are specialized to pass signals to individual target cells, and synapses are the means by which they do so. At a synapse, the plasma membrane of the signal-passing neuron (the ''presynaptic'' neuron) comes into close apposition with the membrane of the target (''postsynaptic'') cell. Both the presynaptic and postsynaptic sites contain extensive arrays of Molecular biology, molecular machinery that link the two membranes together and carry out the signaling process. In many synapses, the presynaptic part is located on an axon and the postsynaptic part is located on a dendrite or soma (biology), soma. Astrocytes also exchange information with the synaptic neurons, responding to synaptic activity and, in turn, r ...
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Caenorhabditis Elegans
''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek ''caeno-'' (recent), ''rhabditis'' (rod-like) and Latin ''elegans'' (elegant). In 1900, Maupas initially named it '' Rhabditides elegans.'' Osche placed it in the subgenus ''Caenorhabditis'' in 1952, and in 1955, Dougherty raised ''Caenorhabditis'' to the status of genus. ''C. elegans'' is an unsegmented pseudocoelomate and lacks respiratory or circulatory systems. Most of these nematodes are hermaphrodites and a few are males. Males have specialised tails for mating that include spicules. In 1963, Sydney Brenner proposed research into ''C. elegans,'' primarily in the area of neuronal development. In 1974, he began research into the molecular and developmental biology of ''C. elegans'', which has since been extensively used as a model organism. It was the first mult ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research ins ...
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Damon Runyon Cancer Research Foundation
The Damon Runyon Cancer Research Foundation (Damon Runyon) is an American not-for-profit cancer research organization focused on "discovering the talent to discover the cure". The organization states that its goals are to: "identify the best and brightest early career scientists in cancer research, accelerate the translation of scientific discoveries into new diagnostic tools and treatments, and to enable risk-taking on bold new ideas". The organization was founded in 1946 by media personality Walter Winchell in New York City, New York, under the name Damon Runyon Cancer Memorial Fund in memory of his colleague and friend Damon Runyon, a newspaperman and author. History Almost immediately after Runyon's passing on December 10, 1946, Winchell went on the air and asked his audience for contributions to cancer research: Mr. and Mrs. United States! A very dear friend of mine a great newspaperman, a great writer, and a very great guy Damon Runyon, was killed this week by Americ ...
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Drosophila
''Drosophila'' () is a genus of flies, belonging to the family Drosophilidae, whose members are often called "small fruit flies" or (less frequently) pomace flies, vinegar flies, or wine flies, a reference to the characteristic of many species to linger around overripe or rotting fruit. They should not be confused with the Tephritidae, a related family, which are also called fruit flies (sometimes referred to as "true fruit flies"); tephritids feed primarily on unripe or ripe fruit, with many species being regarded as destructive agricultural pests, especially the Mediterranean fruit fly. One species of ''Drosophila'' in particular, '' D. melanogaster'', has been heavily used in research in genetics and is a common model organism in developmental biology. The terms "fruit fly" and "''Drosophila''" are often used synonymously with ''D. melanogaster'' in modern biological literature. The entire genus, however, contains more than 1,500 species and is very diverse in appearan ...
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Apoptosis
Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes ( morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay. The average adult human loses between 50 and 70 billion cells each day due to apoptosis. For an average human child between eight and fourteen years old, approximately twenty to thirty billion cells die per day. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo apoptosis. Unlike necrosis, apoptosis produces cell fragments called apop ...
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Cell Biologist
Cell biology (also cellular biology or cytology) is a branch of biology that studies the structure, function, and behavior of cells. All living organisms are made of cells. A cell is the basic unit of life that is responsible for the living and functioning of organisms. Cell biology is the study of structural and functional units of cells. Cell biology encompasses both prokaryotic and eukaryotic cells and has many subtopics which may include the study of cell metabolism, cell communication, cell cycle, biochemistry, and cell composition. The study of cells is performed using several microscopy techniques, cell culture, and cell fractionation. These have allowed for and are currently being used for discoveries and research pertaining to how cells function, ultimately giving insight into understanding larger organisms. Knowing the components of cells and how cells work is fundamental to all biological sciences while also being essential for research in biomedical fields such as ...
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Chlamydomonas Reinhardtii
''Chlamydomonas reinhardtii'' is a single-cell green alga about 10 micrometres in diameter that swims with two flagella. It has a cell wall made of hydroxyproline-rich glycoproteins, a large cup-shaped chloroplast, a large pyrenoid, and an eyespot that senses light. ''Chlamydomonas'' species are widely distributed worldwide in soil and fresh water. ''Chlamydomonas reinhardtii'' is an especially well studied biological model organism, partly due to its ease of culturing and the ability to manipulate its genetics. When illuminated, ''C. reinhardtii'' can grow photoautotrophically, but it can also grow in the dark if supplied with organic carbon. Commercially, ''C. reinhardtii'' is of interest for producing biopharmaceuticals and biofuel, as well being a valuable research tool in making hydrogen. History The ''C. reinhardtii'' wild-type laboratory strain c137 (mt+) originates from an isolate collected near Amherst, Massachusetts, in 1945 by Gilbert M. Smith. The species' name ha ...
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Smithsonian Tropical Research Institute
The Smithsonian Tropical Research Institute (STRI, es, Instituto Smithsonian de Investigaciones Tropicales) is located in Panama and is the only bureau of the Smithsonian Institution based outside of the United States. It is dedicated to understanding the past, present, and future of tropical ecosystems and their relevance to human welfare. STRI grew out of a small field station established in 1923 on Barro Colorado Island in the Panama Canal Zone to become one of the world's leading tropical research organizations. STRI's facilities provide for long-term ecological studies in the tropics and are used by some 1,200 visiting scientists from academic and research institutions around the world every year. History Smithsonian scientists first came to Panama during the construction of the Panama Canal from 1904 to 1914. The Secretary of the Smithsonian Institution, Charles Doolittle Walcott, reached an agreement with Federico Boyd to conduct a biological inventory of the new Canal Zo ...
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