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DOXP
1-Deoxy--xylulose 5-phosphate is an intermediate in the non-mevalonate pathway. See also * DXP synthase * DXP reductoisomerase DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and 2-C-methyl-D-erythritol 4-phosphate (MEP). Image:DOXP.png, 1-Deoxy-D-xylulose 5-phosphate ... Monosaccharide derivatives Organophosphates {{biochemistry-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-mevalonate Pathway
The non-mevalonate pathway—also appearing as the mevalonate-independent pathway and the 2-''C''-methyl-D-erythritol 4-phosphate/1-deoxy-D-xylulose 5-phosphate (MEP/DOXP) pathway—is an alternative metabolic pathway for the biosynthesis of the isoprenoid precursors isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP). The currently preferred name for this pathway is the MEP pathway, since MEP is the first committed metabolite on the route to IPP. Isoprenoid precursor biosynthesis The classical mevalonate pathway (MVA pathway or HMG-CoA reductase pathway) is a metabolic pathway for the biosynthesis of isoprenoid precursors: IPP and DMAPP. The MVA pathway is present in most eukaryotes and some bacteria. IPP and DMAPP serve as the basis for the biosynthesis of isoprenoid (terpenoid) molecules used in processes as diverse as protein prenylation, cell membrane maintenance, the synthesis of hormones, protein anchoring and ''N''-glycosylation in all three domai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DXP Reductoisomerase
DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and 2-C-methyl-D-erythritol 4-phosphate (MEP). Image:DOXP.png, 1-Deoxy-D-xylulose 5-phosphate Image:MEP.png, 2-C-methyl-D-erythritol 4-phosphate It is classified under . It is normally abbreviated DXR, but it is sometimes named IspC, as the product of the ''ispC'' gene. DXR is part of the MEP pathway (nonmevalonate pathway) of isoprenoid precursor biosynthesis. DXR is inhibited by fosmidomycin. This enzyme is required for terpenoid biosynthesis in some organisms, since it is a key enzyme on the MEP pathway for the production of the isoprenoid precursors IPP and DMAPP. In ''Arabidopsis thaliana'' 1-deoxy-D-xylulose 5-phosphate reductoisomerase is the first committed enzyme of the MEP pathway for isoprenoid The terpenoids, also known as isoprenoids, are a class of naturally occurring organic chemicals derived from the 5-ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DXP Synthase
In enzymology, a 1-deoxy--xylulose-5-phosphate synthase () is an enzyme in the non-mevalonate pathway that catalyzes the chemical reaction :pyruvate + -glyceraldehyde 3-phosphate \rightleftharpoons 1-deoxy--xylulose 5-phosphate + CO2 Thus, the two substrates of this enzyme are pyruvate and -glyceraldehyde 3-phosphate, whereas its two products are 1-deoxy--xylulose 5-phosphate and CO2. This enzyme belongs to the family of transferases, specifically those transferring aldehyde or ketonic groups (transaldolases and transketolases, respectively). The systematic name of this enzyme class is pyruvate:-glyceraldehyde-3-phosphate acetaldehydetransferase (decarboxylating). Other names in common use include 1-deoxy--xylulose-5-phosphate pyruvate-lyase (carboxylating), and DXP-synthase. This enzyme participates in biosynthesis of steroids. Structural studies As of late 2007, two structures A structure is an arrangement and organization of interrelated elements in a material ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monosaccharide Derivatives
Monosaccharides (from Greek '' monos'': single, '' sacchar'': sugar), also called simple sugars, are the simplest forms of sugar and the most basic units (monomers) from which all carbohydrates are built. They are usually colorless, water- soluble, and crystalline solids. Contrary to their name (sugars), only some monosaccharides have a sweet taste. Most monosaccharides have the formula (though not all molecules with this formula are monosaccharides). Examples of monosaccharides include glucose (dextrose), fructose (levulose), and galactose. Monosaccharides are the building blocks of disaccharides (such as sucrose and lactose) and polysaccharides (such as cellulose and starch). The table sugar used in everyday vernacular is itself a disaccharide sucrose comprising one molecule of each of the two monosaccharides D-glucose and D-fructose. Each carbon atom that supports a hydroxyl group is chiral, except those at the end of the chain. This gives rise to a number of isomeric ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
