Duplicated Ureter
Duplicated ureter or duplex collecting system is a congenital condition in which the ureteric bud, the embryological origin of the ureter, splits (or arises twice), resulting in two ureters draining a single kidney. It is the most common renal abnormality, occurring in approximately 1% of the population.Siomou E. et alDuplex collecting system diagnosed during the first 6 years of life after a first urinary tract infection: a study of 63 children Journal of Urology, 2006; 175(2):678-81; discussion 681-2J. Gatti, J. Murphy, J. Williams, H. Koo, emedicine overviewUreteral Duplication, Ureteral Ectopia, and Ureterocele/ref> Pathophysiology Ureteral development begins in the human fetus around the 4th week of embryonic development. A ureteric bud, arising from the mesonephric (or Wolffian) duct, gives rise to the ureter, as well as other parts of the collective system. In the case of a duplicated ureter, the ureteric bud either splits or arises twice. In most cases, the kidney is divid ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ectopic Ureter
Ectopic ureter (or ureteral ectopia) is a medical condition where the ureter, rather than terminating at the urinary bladder, terminates at a different site. In males this site is usually the urethra, in females this is usually the urethra or vagina. It can be associated with renal dysplasia, frequent urinary tract infections, and urinary incontinence (usually continuous drip incontinence). Ectopic ureters are found in 1 of every 2000–4000 patients, and can be difficult to diagnose, but are most often seen on CT scans. Ectopic ureter is commonly a result of a duplicated renal collecting system, a duplex kidney with 2 ureters. In this case, usually one ureter drains correctly to the bladder, with the duplicated ureter presenting as ectopic. The embryology that explains the pathology of an ectopic ureter is a cephalad origin of the ureteral bud on the mesonephric duct. With an abnormally long common excretory duct, the ureter never becomes incorporated into the bladder, and, th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ureterocele
A ureterocele is a congenital abnormality found in the ureter. In this condition the distal ureter balloons at its opening into the bladder, forming a sac-like pouch. It is most often associated with a duplicated collection system, where two ureters drain their respective kidney instead of one. Simple ureterocele, where the condition involves only a single ureter, represents only twenty percent of cases. Since the advent of the ultrasound, most ureteroceles are diagnosed prenatally. The pediatric and adult conditions are often found incidentally, i.e., through diagnostic imaging performed for unrelated reasons. Classification ; Intravesical : Confined within the bladder ; Ectopic : Some part extends to the bladder neck or urethra ; Stenotic : Intravesical ureterocele with a narrow opening ; Sphincteric : Ectopic ureterocele with an orifice distal to the bladder neck ; Sphincterostenotic : Orifice is both stenotic and distal to the bladder neck ; Cecoureterocele : Ectopic ureteroc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Kidney Development
Kidney development, or nephrogenesis, describes the embryology, embryologic origins of the kidney, a major organ in the urinary system. This article covers a 3 part developmental process that is observed in most reptiles, birds and mammals, including humans. Nephrogenesis is often considered in the broader context of the development of the urinary and reproductive organs. Phases The development of the kidney proceeds through a series of successive phases, each marked by the development of a more advanced kidney: the archinephros, pronephros, mesonephros, and metanephros. The pronephros is the most immature form of kidney, while the metanephros is most developed. The metanephros persists as the definitive adult kidney. Archinephros The archinephros is considered as hypothetical or primitive kidney. Pronephros The pronephros develops in the cervical region of the embryo. During approximately day 22 of human gestation, the paired pronephri appears towards the cranial end of the int ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vesicoureteral Reflux
Vesicoureteral reflux (VUR), also known as vesicoureteric reflux, is a condition in which urine flows retrograde, or backward, from the urinary bladder, bladder into one or both ureters and then to the renal calyx or kidneys. Urine normally travels in one direction (forward, or anterograde) from the kidneys to the bladder via the ureters, with a one-way valve at the vesicoureteral (ureteral-bladder) junction preventing backflow. The valve is formed by oblique tunneling of the distal ureter through the wall of the bladder, creating a short length of ureter (1–2 cm) that can be compressed as the bladder fills. Reflux occurs if the ureter enters the bladder without sufficient tunneling, i.e., too "end-on". Signs and symptoms Most children with vesicoureteral reflux are asymptomatic. Vesicoureteral reflux may be diagnosed as a result of further evaluation of hydronephrosis, dilation of the kidney or hydroureter, ureters draining urine from the kidney while in utero as well a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urinary Tract Infection
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. Lower urinary tract infections may involve the bladder (cystitis) or urethra (urethritis) while upper urinary tract infections affect the kidney (pyelonephritis). Symptoms from a lower urinary tract infection include suprapubic pain, painful urination (dysuria), frequency and urgency of urination despite having an empty bladder. Symptoms of a kidney infection, on the other hand, are more systemic and include fever or Abdominal pain, flank pain usually in addition to the symptoms of a lower UTI. Rarely, the urine may appear Hematuria, bloody. Symptoms may be vague or non-specific at the extremities of age (i.e. in patients who are very young or old). The most common cause of infection is ''Escherichia coli'', though other bacteria or fungi may sometimes be the cause. Risk factors include female anatomy, sexual intercourse, diabetes mellitus, diabetes, obesity, catheterisation, and famil ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hydronephrosis
Hydronephrosis is the hydrostatic dilation of the renal pelvis and Renal calyx, calyces as a result of obstruction to urine flow downstream. Alternatively, hydroureter describes the dilation of the ureter, and hydronephroureter describes the dilation of the entire upper urinary tract (both the renal pelvicalyceal system and the ureter). Signs and symptoms The signs and symptoms of hydronephrosis depend upon whether the obstruction is Acute (medicine), acute or Chronic (medicine), chronic, partial or complete, unilateral or bilateral. Hydronephrosis that occurs acutely with sudden onset (as caused by a kidney stone) can cause intense pain in the flank area (between the hips and ribs) known as a renal colic. Historically, this type of pain has been described as "Dietl's crisis". Conversely, hydronephrosis that develops gradually over time will generally cause either a dull discomfort or no pain. Nausea and vomiting may also occur. An obstruction that occurs at the urethra or bla ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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African-Americans
African Americans, also known as Black Americans and formerly also called Afro-Americans, are an American racial and ethnic group that consists of Americans who have total or partial ancestry from any of the Black racial groups of Africa. African Americans constitute the second largest ethno-racial group in the U.S. after White Americans. The term "African American" generally denotes descendants of Africans enslaved in the United States. In 2023, an estimated 48.3 million people self-identified as Black, making up 14.4% of the country’s population. This marks a 33% increase since 2000, when there were 36.2 million Black people living in the U.S. African-American history began in the 16th century, with Africans being sold to European slave traders and transported across the Atlantic to the Western Hemisphere. They were sold as slaves to European colonists and put to work on plantations, particularly in the southern colonies. A few were able to achieve freedom through ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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White Americans
White Americans (sometimes also called Caucasian Americans) are Americans who identify as white people. In a more official sense, the United States Census Bureau, which collects demographic data on Americans, defines "white" as "[a] person having origins in any of the original peoples of Europe, the Middle East, or North Africa". This group constitutes the majority of the people in the United States, although their proportion of the overall population has been White demographic decline, gradually declining. As of the latest American Community Survey in 2023, the US Census Bureau estimates that 60.5% of the US population, or 202,651,650 people, are White alone, while Non-Hispanic whites, Non-Hispanic Whites make up 57.1% of the population. Overall, 72.3% of Americans identify as White alone or in combination. European Americans are by far the largest panethnic group of white Americans and have constituted the majority population of the United States since the nation's founding. M ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vulval Vestibule
The vulval vestibule (also known as the vulvar vestibule or vestibule of vagina) is the part of the vulva between the labia minora. At the innermost part are the vaginal introitus and urinary meatus. The Bartholin's and Skene's glands each have two openings to the vestibule on the inside. The outer edge, marked by a coloration difference in the tissues, is called Hart's line, named after David Berry Hart. The vestibule represents the distal end of the urogenital sinus of the embryo.''Manual of Obstetrics''. (3rd ed.). Elsevier. pp. 1–16. . Structure Structures opening in the vulval vestibule are the urethra ( urinary meatus), vagina, Bartholin's glands, and Skene's glands. The external urethral orifice is placed about 25–30 millimetres (1–1.2 in) behind the clitoris and immediately in front of that of the vagina; it usually assumes the form of a short, sagittal cleft with slightly raised margins. Nearby are the openings of the Skene's ducts. The vaginal ori ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Urethra
The urethra (: urethras or urethrae) is the tube that connects the urinary bladder to the urinary meatus, through which Placentalia, placental mammals Urination, urinate and Ejaculation, ejaculate. The external urethral sphincter is a striated muscle that allows voluntary control over urination. The Internal urethral sphincter, internal sphincter, formed by the involuntary smooth muscles lining the bladder neck and urethra, receives its nerve supply by the Sympathetic nervous system, sympathetic division of the autonomic nervous system. The internal sphincter is present both in males and females. Structure The urethra is a fibrous and muscular tube which connects the urinary bladder to the external urethral meatus. Its length differs between the sexes, because it passes through the penis in males. Male In the human male, the urethra is on average long and opens at the end of the external urethral meatus. The urethra is divided into four parts in men, named after the lo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Vagina
In mammals and other animals, the vagina (: vaginas or vaginae) is the elastic, muscular sex organ, reproductive organ of the female genital tract. In humans, it extends from the vulval vestibule to the cervix (neck of the uterus). The #Vaginal opening and hymen, vaginal introitus is normally partly covered by a thin layer of mucous membrane, mucosal tissue called the hymen. The vagina allows for Copulation (zoology), copulation and birth. It also channels Menstruation (mammal), menstrual flow, which occurs in humans and closely related primates as part of the menstrual cycle. To accommodate smoother penetration of the vagina during sexual intercourse or other sexual activity, vaginal moisture increases during sexual arousal in human females and other female mammals. This increase in moisture provides vaginal lubrication, which reduces friction. The texture of the vaginal walls creates friction for the penis during sexual intercourse and stimulates it toward ejaculation, en ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |