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Don Catlin
Donald Hardt Catlin (June 4, 1938 – January 16, 2024) was an American anti- doping scientist. He is one of the founders modern drug-testing in professional sports. Early life and education Catlin was born in New Haven, Connecticut on June 4, 1938. He earned a bachelor's degree in statistics and psychology at Yale University in 1960 and a MD degree from the University of Rochester School of Medicine and Dentistry in 1965. He interned and served in residencies at the University of Vermont and UCLA before serving in the United States Army from 1969 to 1972 during which time he worked at Walter Reed Army Medical Center. Career Catlin oversaw the testing for performance-enhancing drugs at the three most recent Olympics that were held in the United States, starting with the 1984 Summer Games in Los Angeles. He oversaw the testing for the United States Olympic Committee, the National Collegiate Athletic Association (NCAA), Major League Baseball's minor league teams, and the Natio ...
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New Haven, Connecticut
New Haven is a city of the U.S. state of Connecticut. It is located on New Haven Harbor on the northern shore of Long Island Sound. With a population of 135,081 as determined by the 2020 United States census, 2020 U.S. census, New Haven is List of municipalities in Connecticut, the third largest city in Connecticut after Bridgeport, Connecticut, Bridgeport and Stamford, Connecticut, Stamford, the largest city in the South Central Connecticut Planning Region, Connecticut, South Central Connecticut Planning Region, and the principal municipality of Greater New Haven metropolitan area, which had a total population of 864,835 in 2020. New Haven was one of the first Planned community, planned cities in the U.S. A year after its founding by English Puritans in 1638, eight streets were laid out in a four-by-four Grid plan, grid, creating the "Nine Square Plan". The central common block is New Haven Green, the New Haven Green, a square at the center of Downtown New Haven. The Green is n ...
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Major League Baseball
Major League Baseball (MLB) is a professional baseball league composed of 30 teams, divided equally between the National League (baseball), National League (NL) and the American League (AL), with 29 in the United States and 1 in Canada. MLB is one of the major professional sports leagues in the United States and Canada and is considered the premier professional baseball league in the world. Each team plays 162 games per season, with Opening Day traditionally held during the first week of April. Six teams in each league then advance to a four-round Major League Baseball postseason, postseason tournament in October, culminating in the World Series, a best-of-seven championship series between the two league champions first played in 1903. MLB is headquartered in Midtown Manhattan. Formed in 1876 and 1901, respectively, the NL and AL cemented their cooperation with the National Agreement in 1903, making MLB the oldest major professional sports league in the world. They remained le ...
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Patrick Arnold
Patrick Arnold (born 1966) is an American organic chemist known for introducing androstenedione, 1-androstenediol, and methylhexanamine into the dietary supplement market, and for creating the designer steroid tetrahydrogestrinone, also known as THG and "the clear".Creator Of 'The Clear' Imprisoned
CBS News, 04 Aug 2006, retrieved July 2007
THG, along with two other anabolic steroids that Arnold manufactured ( norbolethone and desoxymethyltestosterone (DMT)), not banned at the time of their creati ...
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The Washington Post
''The Washington Post'', locally known as ''The'' ''Post'' and, informally, ''WaPo'' or ''WP'', is an American daily newspaper published in Washington, D.C., the national capital. It is the most widely circulated newspaper in the Washington metropolitan area and has a national audience. As of 2023, the ''Post'' had 130,000 print subscribers and 2.5 million digital subscribers, both of which were the List of newspapers in the United States, third-largest among U.S. newspapers after ''The New York Times'' and ''The Wall Street Journal''. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. In 1933, financier Eugene Meyer (financier), Eugene Meyer purchased it out of bankruptcy and revived its health and reputation; this work was continued by his successors Katharine Graham, Katharine and Phil Graham, Meyer's daughter and son-in-law, respectively, who bought out several rival publications. The ''Post ...
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Anti-Doping Research Inc
In competitive sports, doping is the use of banned athletic performance-enhancing drugs (PEDs) by athletes, as a way of cheating. As stated in the World Anti-Doping Code by WADA, doping is defined as the occurrence of one or more of the anti-doping rule violations outlined in Article 2.1 through Article 2.11 of the Code. The term ''doping'' is widely used by organizations that regulate sporting competitions. The use of drugs to enhance performance is considered unethical and is prohibited by most international sports organizations, including the International Olympic Committee. Furthermore, athletes (or athletic programs) taking explicit measures to evade detection exacerbate the ethical violation with overt deception and cheating. The origins of doping in sports go back to the creation of the sport itself. From ancient usage of substances in chariot racing to more recent controversies in doping in baseball, doping in tennis, doping at the Olympic Games, and doping at the Tour ...
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United States Anti-Doping Agency
The United States Anti-Doping Agency (USADA, ) is a non-profit, non-governmental 501(c)(3) organization and the national anti-doping organization (NADO) for the United States. To protect clean competition and the integrity of sport and prevent doping in the United States with a performance-enhancing substance, the USADA provides education, leads scientific initiatives, conducts testing, and oversees the results management process. Headquartered in Colorado Springs, Colorado, USADA is a signatory to the World Anti-Doping Code, which harmonizes anti-doping practices around the world, and is widely considered the basis for the strongest and strictest anti-doping programs to prevent doping in sport. In 2001, USADA was recognized by the U.S. Congress as "the official anti-doping agency for Olympic, Pan American and Paralympic sport in the United States." While USADA is not a government entity, it is partly funded by the Office of National Drug Control Policy (ONDCP), with its re ...
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Trevor Graham
Trevor Graham (born 20 August 1963) is a Jamaican-born American former sprinter and athletics coach. Following the BALCO scandal, the US Olympic Committee barred him indefinitely from all its training sites. Athletics career Graham was part of the silver medal-winning Jamaican 4 × 400 m team at the 1988 Summer Olympics, running in the first round and semi-final, though not the final. He is a graduate from Saint Augustine's College with a degree in Business Management. Doping scandal BALCO Graham first played a critical whistleblower role in the BALCO scandal (Bay Area Laboratory Co-operative) of June 2003, anonymously sending a syringe containing the designer steroid tetrahydrogestrinone to the United States Anti-Doping Agency. The syringe started the investigation. Many others accused him of trying to wipe out a rival. Eventually the investigation came back to Graham, and he was charged with making false statements about his ties to a steroids distributor. He was conv ...
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Newsweek
''Newsweek'' is an American weekly news magazine based in New York City. Founded as a weekly print magazine in 1933, it was widely distributed during the 20th century and has had many notable editors-in-chief. It is currently co-owned by Dev Pragad, the president and chief executive officer (CEO), and Johnathan Davis, who sits on the board; each owns 50% of the company. In August 2010, revenue decline prompted Graham Holdings, the Washington Post Company to sell ''Newsweek'' to the audio pioneer Sidney Harman for one US dollar and an assumption of the magazine's liabilities. Later that year, ''Newsweek'' merged with the news and opinion website ''The Daily Beast'', forming The Newsweek Daily Beast Company, later called ''NewsBeast''. ''Newsweek'' was jointly owned by the estate of Harman and the company IAC (company), IAC. ''Newsweek'' continued to experience financial difficulties, leading to the suspension of print publication at the end of 2012. In 2013, IBT Media acquired ...
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Tetrahydrogestrinone
Tetrahydrogestrinone (THG), known by the nickname The Clear, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed for medical use. It was developed by Patrick Arnold and was used by a number of high-profile athletes such as Barry Bonds and Dwain Chambers. Non-medical uses THG was developed completely in secret by Patrick Arnold as a designer drug, on the basis that doping testers would be unlikely to detect a totally new compound. Arnold developed a chemical similar to two obscure steroids marketed by BALCO, norbolethone and desoxymethyltestosterone, which had been reported in scientific literature but never entered mass production, and the banned anabolic steroids trenbolone and gestrinone, the latter of which was used to synthesize it. In 2003, whistleblower Trevor Graham passed a spent syringe containing a small amount of the drug to the United States Anti-Doping Agency. This was then transferred to the research group of pharmaco ...
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BALCO
The Bay Area Laboratory Co-operative (BALCO) was an American company that operated from 1983 to 2003 led by founder and owner Victor Conte. In 2003, journalists Lance Williams and Mark Fainaru-Wada investigated the company's role in a drug sports scandal later referred to as the BALCO scandal. BALCO marketed tetrahydrogestrinone ("the Clear"), a then-undetected, performance-enhancing steroid developed by chemist Patrick Arnold. Conte, BALCO vice president James Valente, weight trainer Greg Anderson and coach Remi Korchemny had supplied a number of high-profile sports stars from the United States and Europe with "the Clear" and human growth hormone for several years. History Headquartered in Burlingame, California, BALCO was founded in 1984. Officially, BALCO was a service business for blood and urine analysis and food supplements. In 1988, Victor Conte offered free blood and urine tests to a group of athletes known as the ''BALCO Olympians''. He then was allowed to attend ...
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Norbolethone
Norboletone () (former proposed brand name Genabol), or norbolethone, is a synthetic and orally active anabolic–androgenic steroid (AAS) which was never marketed. It was first developed in 1966 by Wyeth Laboratories and was investigated for use as an agent to encourage weight gain and for the treatment of short stature, but was never marketed commercially because of fears that it might be toxic. It subsequently showed up in urine tests on athletes in competition in the early 2000s. Norboletone was found to have been brought to the market by the chemist Patrick Arnold, of the Bay Area Laboratory Co-operative (BALCO), an American nutritional supplement company. It is reputed to have been the active ingredient in the original formulation of the "undetectable" steroid formulation known as "The Clear" before being replaced by the more potent drug tetrahydrogestrinone. In 2002, Don Catlin, the founder and then-director of the UCLA Olympic Analytical Lab, identified norboletone for t ...
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Erythropoietin
Erythropoietin (; EPO), also known as erythropoetin, haematopoietin, or haemopoietin, is a glycoprotein cytokine secreted mainly by the kidneys in response to cellular hypoxia; it stimulates red blood cell production ( erythropoiesis) in the bone marrow. Low levels of EPO (around 10  mU/mL) are constantly secreted in sufficient quantities to compensate for normal red blood cell turnover. Common causes of cellular hypoxia resulting in elevated levels of EPO (up to 10 000 mU/mL) include any anemia, and hypoxemia due to chronic lung disease. Erythropoietin is largely synthesized by fibroblast-like type-1 interstitial cells, located primarily in the deep renal cortex in close association with the peritubular capillaries and proximal convoluted tubule; it is also produced in perisinusoidal cells in the liver. Liver production predominates in the fetal and perinatal period; renal production predominates in adulthood. It is homologous with thrombopoietin. ...
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