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Dolly (sheep)
Dolly (5 July 1996 – 14 February 2003) was a female Finnish Dorset sheep and the first mammal cloned from an adult somatic cell. She was cloned by associates of the Roslin Institute in Scotland, using the process of nuclear transfer from a cell taken from a mammary gland. Her cloning proved that a cloned organism could be produced from a mature cell from a specific body part. Contrary to popular belief, she was not the first animal to be cloned. The employment of adult somatic cells in lieu of embryonic stem cells for cloning emerged from the foundational work of John Gurdon, who cloned African clawed frogs in 1958 with this approach. The successful cloning of Dolly led to widespread advancements within stem cell research, including the discovery of induced pluripotent stem cells. Dolly lived at the Roslin Institute throughout her life and produced several lambs. She was euthanized at the age of six years due to a progressive lung disease. No cause which linked the disea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taxidermy
Taxidermy is the art of preserving an animal's body via mounting (over an armature) or stuffing, for the purpose of display or study. Animals are often, but not always, portrayed in a lifelike state. The word ''taxidermy'' describes the process of preserving the animal, but the word is also used to describe the end product, which are called taxidermy mounts or referred to simply as "taxidermy". The word ''taxidermy'' is derived from the Greek words ''taxis'' and ''derma''. ''Taxis'' means "arrangement", and ''derma'' means "skin" (the dermis). The word ''taxidermy'' translates to "arrangement of skin". Taxidermy is practiced primarily on vertebrates (mammals, birds, fish, reptiles, and less commonly on amphibians) but can also be done to larger insects and arachnids under some circumstances. Taxidermy takes on a number of forms and purposes including hunting trophies and natural history museum displays. Museums use taxidermy as a method to record species, including those th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
African Clawed Frog
The African clawed frog (''Xenopus laevis'', also known as the xenopus, African clawed toad, African claw-toed frog or the ''platanna'') is a species of African aquatic frog of the family Pipidae. Its name is derived from the three short claws on each hind foot, which it uses to tear apart its food. The word ''Xenopus'' means 'strange foot' and ''laevis'' means 'smooth'. The species is found throughout much of Sub-Saharan Africa (Nigeria and Sudan to South Africa),Weldon; du Preez; Hyatt; Muller; and Speare (2004). Origin of the Amphibian Chytrid Fungus.' Emerging Infectious Diseases 10(12). and in isolated, introduced populations in North America, South America, Europe, and Asia. All species of the family Pipidae are tongueless, toothless and completely aquatic. They use their hands to shove food in their mouths and down their throats and a hyobranchial pump to draw or suck things in their mouth. Pipidae have powerful legs for swimming and lunging after food. They also use the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blastocyst
The blastocyst is a structure formed in the early embryonic development of mammals. It possesses an inner cell mass (ICM) also known as the ''embryoblast'' which subsequently forms the embryo, and an outer layer of trophoblast cells called the trophectoderm. This layer surrounds the inner cell mass and a fluid-filled cavity known as the blastocoel. In the late blastocyst the trophectoderm is known as the trophoblast. The trophoblast gives rise to the chorion and amnion, the two fetal membranes that surround the embryo. The placenta derives from the embryonic chorion (the portion of the chorion that develops villi) and the underlying uterine tissue of the mother. The name "blastocyst" arises from the Greek ' ("a sprout") and ' ("bladder, capsule"). In other animals this is a structure consisting of an undifferentiated ball of cells and is called a blastula. In humans, blastocyst formation begins about five days after fertilization when a fluid-filled cavity opens up i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oocyte
An oocyte (, ), oöcyte, or ovocyte is a female gametocyte or germ cell involved in reproduction. In other words, it is an immature ovum, or egg cell. An oocyte is produced in a female fetus in the ovary during female gametogenesis. The female germ cells produce a primordial germ cell (PGC), which then undergoes mitosis, forming oogonia. During oogenesis, the oogonia become primary oocytes. An oocyte is a form of genetic material that can be collected for cryoconservation. Formation The formation of an oocyte is called oocytogenesis, which is a part of oogenesis. Oogenesis results in the formation of both primary oocytes during fetal period, and of secondary oocytes after it as part of ovulation. Characteristics Cytoplasm Oocytes are rich in cytoplasm, which contains yolk granules to nourish the cell early in development. Nucleus During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle. The only normal human type of secondary oocyte h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Somatic Cell Nuclear Transfer
In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. The technique consists of taking an enucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell. It is used in both therapeutic and reproductive cloning. In 1996, Dolly the sheep became famous for being the first successful case of the reproductive cloning of a mammal. In January 2018, a team of scientists in Shanghai announced the successful cloning of two female crab-eating macaques (named Zhong Zhong and Hua Hua) from foetal nuclei. "Therapeutic cloning" refers to the potential use of SCNT in regenerative medicine; this approach has been championed as an answer to the many issues concerning embryonic stem cells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types truly are. Introduction Somatic cell nuclear transfer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scientific American
''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many famous scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it. In print since 1845, it is the oldest continuously published magazine in the United States. ''Scientific American'' is owned by Springer Nature, which in turn is a subsidiary of Holtzbrinck Publishing Group. History ''Scientific American'' was founded by inventor and publisher Rufus Porter (painter), Rufus Porter in 1845 as a four-page weekly newspaper. The first issue of the large format newspaper was released August 28, 1845. Throughout its early years, much emphasis was placed on reports of what was going on at the United States Patent and Trademark Office, U.S. Patent Office. It also reported on a broad range of inventions including perpetual motion machines, an 1860 device for buoying vessels by Abraham Lincoln, and the universal joint which now can be found ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BBC News
BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadcast news organisation and generates about 120 hours of radio and television output each day, as well as online news coverage. The service maintains 50 foreign news bureaus with more than 250 correspondents around the world. Deborah Turness has been the CEO of news and current affairs since September 2022. In 2019, it was reported in an Ofcom report that the BBC spent £136m on news during the period April 2018 to March 2019. BBC News' domestic, global and online news divisions are housed within the largest live newsroom in Europe, in Broadcasting House in central London. Parliamentary coverage is produced and broadcast from studios in London. Through BBC English Regions, the BBC also has regional centres across England and national new ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Department For Environment, Food And Rural Affairs
The Department for Environment, Food and Rural Affairs (Defra) is a department of His Majesty's Government responsible for environmental protection, food production and standards, agriculture, fisheries and rural communities in the United Kingdom. Concordats set out agreed frameworks for co operation, between it and the Scottish Government, Welsh Government and Northern Ireland Executive, which have devolved responsibilities for these matters in their respective nations. Defra also leads for the United Kingdom on agricultural, fisheries and environmental matters in international negotiations on sustainable development and climate change, although a new Department of Energy and Climate Change was created on 3 October 2008 to take over the last responsibility; later transferred to the Department for Business, Energy and Industrial Strategy following Theresa May's appointment as Prime Minister in July 2016. Creation The department was formed in June 2001, under the leader ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edinburgh
Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian on the southern shore of the Firth of Forth. Edinburgh is Scotland's List of towns and cities in Scotland by population, second-most populous city, after Glasgow, and the List of cities in the United Kingdom, seventh-most populous city in the United Kingdom. Recognised as the capital of Scotland since at least the 15th century, Edinburgh is the seat of the Scottish Government, the Scottish Parliament and the Courts of Scotland, highest courts in Scotland. The city's Holyrood Palace, Palace of Holyroodhouse is the official residence of the Monarchy of the United Kingdom, British monarchy in Scotland. The city has long been a centre of education, particularly in the fields of medicine, Scots law, Scottish law, literature, philosophy, the sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Edinburgh
The University of Edinburgh ( sco, University o Edinburgh, gd, Oilthigh Dhùn Èideann; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Granted a royal charter by King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played an important role in Edinburgh becoming a chief intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the "Athens of the North." Edinburgh is ranked among the top universities in the United Kingdom and the world. Edinburgh is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2021, it had a total income of £1.176 billion, of w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ian Wilmut
Sir Ian Wilmut, OBE FRS -- FMedSci FRSE (born 7 July 1944) is an English embryologist and Chair of the Scottish Centre for Regenerative Medicine at the University of Edinburgh. He is best known as the leader of the research group that in 1996 first cloned a mammal from an adult somatic cell, a Finnish Dorset lamb named Dolly. He was appointed OBE in 1999 for services to embryo development and knighted in the 2008 New Year Honours. He together with Keith Campbell and Shinya Yamanaka jointly received the 2008 Shaw Prize for Medicine and Life Sciences "for their works on the cell differentiation in mammals." Early life and education Wilmut was born in Hampton Lucy, Warwickshire, England. Wilmut's father, Leonard Wilmut, was a mathematics teacher who suffered from diabetes for fifty years, which eventually caused him to become blind. He was a student of the former Boys' High School, in Scarborough, where his father taught. Wilmut's early desire was to embark on a naval c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
