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David Ho (scientist)
David Da-i Ho (; pinyin: ''Hé Dà-yī''; born November 3, 1952) is a Taiwanese American, Taiwanese-American HIV/AIDS research, AIDS researcher, physician, and Virology, virologist who has made a number of scientific contributions to the understanding and HAART, treatment of HIV infection. He was a pioneer of Combination therapy, combination anti-retroviral therapy instead of monotherapy, single therapy, which turned HIV from an absolute terminal disease into a chronic disease. Ho was born in Taiwan in 1952 and immigrated to the United States in 1965. After graduating from the California Institute of Technology, he earned his Doctor of Medicine (M.D.) from Harvard Medical School before receiving his clinical training at the UCLA School of Medicine and Massachusetts General Hospital. He is the founding scientific director of the Aaron Diamond AIDS Research Center and the Clyde and Helen Wu Professor of Medicine at Columbia University Vagelos College of Physicians and Surgeons, ...
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Taichung
Taichung (, Wade–Giles: '), officially Taichung City, is a special municipality (Taiwan), special municipality in central Taiwan. Taichung is Taiwan's second-largest city, with more than 2.85 million residents, making it the largest city in Central Taiwan. It serves as the core of the Taichung–Changhua metropolitan area, Taiwan's second-largest metropolitan area. Located in the Taichung Basin, the city was initially developed from several scattered hamlets helmed by the Taiwanese indigenous peoples. It was constructed to be the new capital of Taiwan Province and renamed "Taiwanfu (other), Taiwan-fu" in the late Taiwan under Qing rule, Qing dynastic era between 1887 and 1894. During the Taiwan under Japanese rule, Japanese era from 1895, the urban planning of present-day Taichung was performed and developed by the Japanese. The urban area of Taichung was organized as a Provincial city (Taiwan), provincial city from the start of ROC rule in 1945 until 25 December 2010, ...
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Time (magazine)
''Time'' (stylized in all caps as ''TIME'') is an American news magazine based in New York City. It was published Weekly newspaper, weekly for nearly a century. Starting in March 2020, it transitioned to every other week. It was first published in New York City on March 3, 1923, and for many years it was run by its influential co-founder, Henry Luce. A European edition (''Time Europe'', formerly known as ''Time Atlantic'') is published in London and also covers the Middle East, Africa, and, since 2003, Latin America. An Asian edition (''Time Asia'') is based in Hong Kong. The South Pacific edition, which covers Australia, New Zealand, and the Pacific Islands, is based in Sydney. Since 2018, ''Time'' has been owned by Salesforce founder Marc Benioff, who acquired it from Meredith Corporation. Benioff currently publishes the magazine through the company Time USA, LLC. History 20th century ''Time'' has been based in New York City since its first issue published on March 3, 1923 ...
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Columbia University Vagelos College Of Physicians And Surgeons
The Columbia University College of Physicians and Surgeons (officially known as Columbia University Roy and Diana Vagelos College of Physicians and Surgeons) is the medical school of Columbia University, located at the Columbia University Irving Medical Center in the Washington Heights neighborhood of Manhattan. Founded in 1767 by Samuel Bard as the medical department of King's College (now Columbia University), the College of Physicians and Surgeons was the first medical school in the Thirteen Colonies to award the Doctor of Medicine (MD) degree. Beginning in 1993, the College of Physicians and Surgeons was also the first U.S. medical school to hold a white coat ceremony. Following a gift of $250 million from Roy and Diana Vagelos in 2017, the school became the first medical school in the nation to replace loans with scholarships for all students who qualify for financial aid when it did so in 2018. Columbia is affiliated with NewYork-Presbyterian Hospital. Students additi ...
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Aaron Diamond AIDS Research Center
Aaron Diamond AIDS Research Center, often abbreviated as ADARC, is a United States medical research institution dedicated to finding a cure for HIV/AIDS. It is headed by scientist Dr. David Ho, who was the 1996 Time magazine Person of the Year, and is located in New York City. Opening in 1991, the center was the brainchild of the Aaron Diamond Foundation headed by his widow Irene Diamond, the New York City Department of Health, the Public Health Research Institute and New York University School of Medicine. It became affiliated with Rockefeller University in 1996, and became part of Columbia University's medical school, Columbia University Vagelos College of Physicians and Surgeons, in 2019. One is the introduction of combination antiretroviral therapy to combat HIV drug resistance and hence prevent progression to fatal full-blown AIDS. David Ho and his team presented their remarkable clinical trial results at the International AIDS Conference 1996. This marked a turning point ...
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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is a teaching hospital located in the West End neighborhood of Boston, Massachusetts. It is the original and largest clinical education and research facility of Harvard Medical School/Harvard University, and houses the world's largest hospital-based research program with an annual research budget of more than $1.2 billion in 2021. It is the third-oldest general hospital in the United States with a patient capacity of 999 beds. Along with Brigham and Women's Hospital, Mass General is a founding member of Mass General Brigham, formerly known as Partners HealthCare, the largest healthcare provider in Massachusetts. History Founded in 1811, the original hospital was designed by the famous American architect Charles Bulfinch. It is the third-oldest general hospital in the United States; only Pennsylvania Hospital (1751) and NewYork-Presbyterian Hospital's predecessor New York Hospital (1771) are older. John Warren, Profess ...
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UCLA School Of Medicine
The UCLA School of Medicine (also known as the David Geffen School of Medicine at UCLA) is the accredited medical school of the University of California, Los Angeles. Founded in 1951, it is the second medical school in the University of California system after the UCSF School of Medicine. History Founding Dating back to its affiliation with the University of California in 1873, the UCSF School of Medicine was the only public medical school in California. This made sense in the late 19th century when most of California's population lived in Northern California and Southern California was a lightly populated desert. It no longer made sense by the 1940s, after Los Angeles had overtaken San Francisco to become the leading metropolis on the West Coast of the United States. Dr. Elmer Belt was instrumental in lobbying for the establishment of the School. Therefore, in 1945, the Board of Regents voted to establish a medical school at UCLA. In 1947, Stafford L. Warren was appoi ...
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Harvard Medical School
Harvard Medical School (HMS) is the medical school of Harvard University and is located in the Longwood Medical and Academic Area, Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is the third oldest medical school in the United States. It provides patient care, medical education, and research training through its 15 clinical affiliates and research institutes, including Massachusetts General Hospital (MGH), Boston Children's Hospital, Dana–Farber Cancer Institute, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Mount Auburn Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, Spaulding Rehabilitation Hospital, and others. Harvard Medical School also partners with newer entities such as Harvard Catalyst, Broad Institute , Broad Institute of MIT and Harvard, Harvard Stem Cell Institute, the Center for Primary Care, and Wyss Institute for Biologically Inspired Engineering. History Harvard ...
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Clinical Medicine (journal)
''Clinical Medicine'' is a bimonthly peer-reviewed medical journal published by the Royal College of Physicians. It was established in 1966 as the ''Journal of the Royal College of Physicians of London''. It carried both names between 1998 and 2000, and since 2001 it has appeared as ''Clinical Medicine''. The editor-in-chief is Prof Anton Emmanuel. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2018 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 2.046, ranking it 58th out of 156 journals in the category "Medicine, General & Internal". References External links * {{Official website, http://www.rcplondon.ac.uk/resources/clinical-medicine-journal Royal College of Physician ...
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Chronic Disease
A chronic condition (also known as chronic disease or chronic illness) is a health condition or disease that is persistent or otherwise long-lasting in its effects or a disease that comes with time. The term ''chronic'' is often applied when the course of the disease lasts for more than three months. Common chronic diseases include diabetes, functional gastrointestinal disorder, eczema, arthritis, asthma, chronic obstructive pulmonary disease, autoimmune diseases, genetic disorders and some viral diseases such as hepatitis C and acquired immunodeficiency syndrome. An illness which is lifelong because it ends in death is a terminal illness. It is possible and not unexpected for an illness to change in definition from terminal to chronic as medicine progresses. Diabetes and HIV for example were once terminal yet are now considered chronic, due to the availability of insulin for diabetics and daily drug treatment for individuals with HIV, which allow these individuals to ...
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Terminal Disease
Terminal illness or end-stage disease is a disease that cannot be cured or adequately treated and is expected to result in the death of the patient. This term is more commonly used for progressive diseases such as cancer, rather than fatal injury. In popular use, it indicates a disease that will progress until death with near absolute certainty, regardless of treatment. A patient who has such an illness may be referred to as a terminal patient, terminally ill or simply as being terminal. There is no standardized life expectancy for a patient to be considered terminal, although it is generally months or less. An illness which is lifelong but not fatal is called a ''chronic condition''. Terminal patients have options for disease management after diagnosis. Examples include caregiving, continued treatment, palliative and hospice care, and physician-assisted suicide. Decisions regarding management are made by the patient and their family, although medical professionals may offer re ...
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Combination Therapy
In mathematics, a combination is a selection of items from a set that has distinct members, such that the order of selection does not matter (unlike permutations). For example, given three fruits, say an apple, an orange and a pear, there are three combinations of two that can be drawn from this set: an apple and a pear; an apple and an orange; or a pear and an orange. More formally, a ''k''-combination of a set ''S'' is a subset of ''k'' distinct elements of ''S''. So, two combinations are identical if and only if each combination has the same members. (The arrangement of the members in each set does not matter.) If the set has ''n'' elements, the number of ''k''-combinations, denoted by C(n,k) or C^n_k, is equal to the binomial coefficient \binom nk = \frac, which can be written using factorials as \textstyle\frac whenever k\leq n, and which is zero when k>n. This formula can be derived from the fact that each ''k''-combination of a set ''S'' of ''n'' members has k! permu ...
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