Daniel E. Koshland, Jr.
Daniel Edward Koshland Jr. (March 30, 1920July 23, 2007) was an American biochemist. He reorganized the study of biology at the University of California, Berkeley, and was the editor of the leading U.S. science journal, ''Science'', from 1985 to 1995. He was a member of the United States National Academy of Sciences, the American Academy of Arts and Sciences, and the American Philosophical Society. Early life Koshland was born to a Jewish family, the son of Daniel E. Koshland Sr. and Eleanor (), daughter of the Haas family patriarch Abraham Haas.Butler Koshland Fellowships: "Daniel E. Koshland Sr. retrieved April 21, 2014 His great-grandfather was wool merchant Simon Koshland. He had two si ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lafayette, California
Lafayette (formerly La Fayette) is a city in Contra Costa County, California, United States. As of 2020, the city's population was 25,391. It was named after the Marquis de Lafayette, a French military officer of the American Revolutionary War. Pronunciation The pronunciation of the "''fay''" in Lafayette can vary among local residents. Common pronunciations include: * (rhymes with the word "fee") * (rhymes with the words "eye" and "bye") * (rhymes with the word "pay") History Before the colonization of the region by Spain, Lafayette and its vicinity were inhabited by the Saclan tribe of the indigenous Bay Miwok. Ohlone also populated some of the areas along Lafayette Creek.''Draft Environmental Impact Report for the East Area Service Center'', Earth Metrics Incorporated, prepared for the East Bay Municipal Utility District, May 1989 The indigenous inhabitants' first contact with Europeans was in the late 18th century with the founding of Catholic missions in t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Simon Koshland
Simon Koshland (1825–1896) was a Bavarian-born American businessman, and wool merchant. He is the patriarch of the Koshland and Haas family of San Francisco.The Jews of San Francisco, by Martin A. Meyer, Ph.D., Emanu-El, San Francisco, June 1916 Biography Simon Koshland was born in Ichenhausen, Kingdom of Bavaria in 1825. In 1850, he immigrated to Sacramento via Panama with his older brother where they opened a general merchandise store. In 1862, he moved to San Francisco after his store was burned down in a flood where he and his brother opened a wool house named ''Koshland Brothers''. The company eventually morphed into ''Koshland & Sons'' and became the leading wool house in America. Koshland retired in the 1890s; his sons and sons-in-law continued the family business. Personal life Koshland married Rosina Franenthal of Philadelphia; they had 8 children: Isidore, Joseph, Marcus, Henrietta, Caroline, Frances, Montefiore, Abraham, and Jesse. His daughter Frances married A ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rockefeller University
The Rockefeller University is a Private university, private Medical research, biomedical Research university, research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is Carnegie Classification of Institutions of Higher Education, classified as a "Special Focus – Research Institution". Rockefeller is the oldest biomedical research institute in the United States. The university is located on the Upper East Side of Manhattan, between 63rd and 68th streets on York Avenue / Sutton Place, York Avenue. Richard P. Lifton became the university's eleventh president on September 1, 2016. The Rockefeller University Press publishes the ''Journal of Experimental Medicine'', the ''Journal of Cell Biology'', and ''The Journal of General Physiology''. In 2018, the faculty included 82 tenured and tenure-track members, including 37 members of the National Academy of Scienc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brookhaven National Laboratory
Brookhaven National Laboratory (BNL) is a United States Department of Energy national laboratories, United States Department of Energy national laboratory located in Upton, New York, a hamlet of the Brookhaven, New York, Town of Brookhaven. It was formally established in 1947 at the site of Camp Upton, a former List of United States Army installations, U.S. Army base on Long Island. Located approximately 60 miles east of New York City, it is managed by Stony Brook University and Battelle Memorial Institute. Research at BNL includes nuclear and high energy physics, energy science and technology, environmental and bioscience, nanoscience, and national security. The 5,300 acre campus contains several large research facilities, including the Relativistic Heavy Ion Collider and National Synchrotron Light Source II. Seven Nobel Prizes have been awarded for work conducted at Brookhaven Lab. Overview BNL operations are overseen by a Department of Energy Site office, is staffed by approx ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Enzyme Kinetics
Enzyme kinetics is the study of the rates of enzyme catalysis, enzyme-catalysed chemical reactions. In enzyme kinetics, the reaction rate is measured and the effects of varying the conditions of the reaction are investigated. Studying an enzyme's chemical kinetics, kinetics in this way can reveal the catalytic mechanism of this enzyme, its role in metabolism, how its activity is controlled, and how a drug or a modifier (Enzyme inhibitor, inhibitor or Enzyme activator, activator) might affect the rate. An enzyme (E) is a protein molecule that serves as a biological catalyst to facilitate and accelerate a chemical reaction in the body. It does this through binding of another molecule, its Substrate (biochemistry), substrate (S), which the enzyme acts upon to form the desired product. The substrate binds to the active site of the enzyme to produce an enzyme-substrate complex ES, and is transformed into an enzyme-product complex EP and from there to product P, via a transition state ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the science, scientific study of the structure, properties, and reactions of organic compounds and organic matter, organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes Physical property, physical and Chemical property, chemical properties, and evaluation of Reactivity (chemistry), chemical reactivity to understand their behavior. The study of organic reactions includes the organic synthesis, chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical (in silico) study. The range of chemicals studied chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Manhattan Project
The Manhattan Project was a research and development program undertaken during World War II to produce the first nuclear weapons. It was led by the United States in collaboration with the United Kingdom and Canada. From 1942 to 1946, the project was directed by Major General Leslie Groves of the United States Army Corps of Engineers, U.S. Army Corps of Engineers. Nuclear physicist J. Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the bombs. The Army program was designated the Manhattan District, as its first headquarters were in Manhattan; the name gradually superseded the official codename, Development of Substitute Materials, for the entire project. The project absorbed its earlier British counterpart, Tube Alloys, and subsumed the program from the American civilian Office of Scientific Research and Development. The Manhattan Project employed nearly 130,000 people at its peak and cost nearly US$2 billion (equivalent to about $ b ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Phillips Exeter Academy
Phillips Exeter Academy (often called Exeter or PEA) is an Independent school, independent, co-educational, college-preparatory school in Exeter, New Hampshire. Established in 1781, it is America's sixth-oldest boarding school and educates an estimated 1,100 boarding and day students in grades 9 to 12, as well as postgraduate year, postgraduate students. Exeter is one of the nation's wealthiest boarding schools, with a financial endowment of $1.6 billion as of June 2024, and houses the Phillips Exeter Academy Library, world's largest high school library. The academy admits students on a Need-blind admission, need-blind basis and offers free tuition to students with family incomes under $125,000. Its List of Phillips Exeter Academy people, list of notable alumni includes U.S. president Franklin Pierce, U.S. senator Daniel Webster, Facebook founder Mark Zuckerberg, and three Nobel Prize recipients. History Origins Phillips Exeter Academy was established in 1781 by John Philli ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sinclair Lewis
Harry Sinclair Lewis (February 7, 1885 – January 10, 1951) was an American novelist, short-story writer, and playwright. In 1930 Nobel Prize in Literature, 1930, he became the first author from the United States (and the first from the Americas) to receive the Nobel Prize in Literature, which was awarded "for his vigorous and graphic art of description and his ability to create, with wit and humor, new types of characters." Lewis wrote six popular novels: ''Main Street (novel), Main Street'' (1920), ''Babbitt (novel), Babbitt'' (1922), ''Arrowsmith (novel), Arrowsmith'' (1925), ''Elmer Gantry'' (1927), ''Dodsworth (novel), Dodsworth'' (1929), and ''It Can't Happen Here'' (1935). Several of his notable works were critical of American capitalism and economic materialism, materialism during the interwar period. Lewis is respected for his strong characterizations of modern working women. H. L. Mencken wrote of him, "[If] there was ever a novelist among us with an authentic call to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Arrowsmith (novel)
''Arrowsmith'' is a novel by American author Sinclair Lewis, first published in 1925. It won the 1926 Pulitzer Prize (which Lewis declined). Lewis was greatly assisted in its preparation by science writer Paul de Kruif, who received 25% of the royalties on sales, although Lewis was listed as the sole author. ''Arrowsmith'' is an early major novel dealing with the culture of science. It was written in the period after the reforms of medical education flowing from the Flexner Report on ''Medical Education in the United States and Canada: A Report to the Carnegie Foundation for the Advancement of Teaching'', 1910, which had called on medical schools in the United States to adhere to mainstream science in their teaching and research. The book was adapted by Hollywood as '' Arrowsmith'' in 1931, starring Ronald Colman and Helen Hayes. Plot ''Arrowsmith'' tells the story of bright and scientifically minded Martin Arrowsmith of Elk Mills, Winnemac (the same fictional state in which ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Paul De Kruif
Paul Henry de Kruif (, rhyming with "life") (March 2, 1890 – February 28, 1971) was an American microbiologist and writer. Publishing as Paul de Kruif, he is known for his 1926 book, ''Microbe Hunters''. This book was not only a bestseller for a lengthy period after publication, but has remained high on lists of recommended reading for science and has been an inspiration for many aspiring physicians and scientists. Biography Early life De Kruif was born March 2, 1890, in Zeeland, Michigan. In 1912, he graduated from the University of Michigan with a bachelor's degree, and he remained there to obtain a Ph.D., which was granted in 1916. He immediately entered service as a private in Mexico on the Pancho Villa Expedition and afterwards served as a lieutenant and a captain in World War I in France. Because of his service in the Sanitary Corps, he had occasional contacts with leading French biologists of the period. Career After returning to the University of Michigan as an assista ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |