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Daniel Djakiew
Daniel Djakiew (born 1956 in Newcastle, Australia) is a scholar, researcher, teacher, and tenured full professor in the Department of Biochemistry and Molecular & Cellular Biology, School of Medicine, Georgetown University, Washington DC. Research At University of Newcastle (1978–1983), he conducted research on the evolution of the male reproductive tract as revealed by monotreme mammals. These studies showed that periurethral glands in the male monotreme represent a rudimentary disseminate prostate (prostate evolution in monotreme mammals),Djakiew, D. (1978). Studies of the Male Reproductive Tract of the Echidna (Tachyglossus aculeatus) with particular emphasis on the Epididymis. Honors Thesis, University of Newcastle, Australia. and that the monotreme epididymis has many similarities to that of reptiles compared with scrotal mammals (epididymis evolution from reptiles to mammals).Djakiew, D. & Jones R.C. (1981). Structural differentiation of the male genital ducts of the ech ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Newcastle, New South Wales
Newcastle ( ; Awabakal: ) is a metropolitan area and the second most populated city in the state of New South Wales, Australia. It includes the Newcastle and Lake Macquarie local government areas, and is the hub of the Greater Newcastle area, which includes most parts of the local government areas of City of Newcastle, City of Lake Macquarie, City of Cessnock, City of Maitland and Port Stephens Council. Located at the mouth of the Hunter River, it is the predominant city within the Hunter Region. Famous for its coal, Newcastle is the largest coal exporting harbour in the world, exporting 159.9 million tonnes of coal in 2017. Beyond the city, the Hunter Region possesses large coal deposits. Geologically, the area is located in the central-eastern part of the Sydney Basin. History Aboriginal history Newcastle and the lower Hunter Region were traditionally occupied by the Awabakal and Worimi Aboriginal people, who called the area Malubimba. Based on Aboriginal lang ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Low-affinity Nerve Growth Factor Receptor
The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR bound other neurotrophins equally well as nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3, Brain-derived neurotrophic factor, and Neurotrophin-4. All neurotrophins bind to p75NTR. This also includes the immature pro-neurotrophin forms. Neurotrophic factor receptors, including p75NTR, are responsible for ensuring a proper density to target ratio of developing neurons, refining broader maps in development into precise connections. p75NTR is involved in pathways that promote neuronal survival and neuronal death. Receptor family p75NTR is a member of the tumor necrosis factor receptor superfamily. p75NTR/LNGFR was the first member of this large family of receptors to be characterized, that now contains about 25 receptors, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Georgetown University Medical Center Faculty
Georgetown or George Town may refer to: Places Africa *George, South Africa, formerly known as Georgetown * Janjanbureh, Gambia, formerly known as Georgetown *Georgetown, Ascension Island, main settlement of the British territory of Ascension Island Asia *Georgetown, Allahabad, India *George Town, Chennai, India *George Town, Penang, capital city of the Malaysian state of Penang Europe * Georgetown, Blaenau Gwent, now part of the town of Tredegar in Wales * Georgetown, Dumfries and Galloway, a location in Dumfries and Galloway, Scotland *Es Castell in Minorca, Spain, originally called Georgetown North and Central America Canada *Georgetown, Alberta * Georgetown, Newfoundland and Labrador *Georgetown, Ontario *Georgetown, Prince Edward Island Caribbean *George Town, Bahamas, a village in Exuma District, Bahamas * George Town, Belize, a village in Stann Creek District, Belize *George Town, Cayman Islands, the capital city on Grand Cayman * Georgetown, Saint Vincent and the Grena ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Newcastle (Australia) Alumni , a university in New South Wales, Australia
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University of Newcastle can refer to: * Newcastle University, a university in the United Kingdom * University of Newcastle (Australia) The University of Newcastle (UON), informally known as Newcastle University, is a public university in Newcastle, New South Wales, Australia. Established in 1965, it has a primary campus in the Newcastle suburb of Callaghan. The university als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Newcastle, New South Wales
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1956 Births
Events January * January 1 – The Anglo-Egyptian Condominium ends in Sudan. * January 8 – Operation Auca: Five U.S. evangelical Christian missionaries, Nate Saint, Roger Youderian, Ed McCully, Jim Elliot and Pete Fleming, are killed for trespassing by the Huaorani people of Ecuador, shortly after making contact with them. * January 16 – Egyptian leader Gamal Abdel Nasser vows to reconquer Palestine. * January 25– 26 – Finnish troops reoccupy Porkkala, after Soviet troops vacate its military base. Civilians can return February 4. * January 26 – The 1956 Winter Olympics open in Cortina d'Ampezzo, Italy. February * February 11 – British spies Guy Burgess and Donald Maclean resurface in the Soviet Union, after being missing for 5 years. * February 14– 25 – The 20th Congress of the Communist Party of the Soviet Union is held in Moscow. * February 16 – The 1956 World Figure Skating Championships open in Garmisch, West Germany. * February 22 – Elvis P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
George Mason University
George Mason University (George Mason, Mason, or GMU) is a public research university in Fairfax County, Virginia with an independent City of Fairfax, Virginia postal address in the Washington, D.C. Metropolitan Area. The university was originally founded in 1949 as a Northern Virginia regional branch of the University of Virginia. Named after Founding Father of the United States George Mason in 1959, it became an independent university in 1972. The school has since grown into the largest public university in the Commonwealth of Virginia. Mason operates four campuses in Virginia (Fairfax, Arlington, Front Royal, and Prince William), as well as a campus in Incheon, South Korea. The flagship campus is in Fairfax. The university is classified among "R1: Doctoral Universities – Very high research activity". Two professors were awarded the Nobel Memorial Prize in Economics during their time at George Mason University: James M. Buchanan in 1986 and Vernon L. Smith in 200 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Angers
The University of Angers (french: Université d'Angers; UA) is a public university in western France, with campuses in Angers, Cholet, and Saumur. It forms part of thAngers-Le Mans University Community History The University of Angers was initially established during the 11th century as the ''School of Angers''. It became known as the ''University of Angers'' in 1337 and was the fifth largest university in France at the time. The university existed until 1793 when all universities in France were closed. Nearly 2 centuries later, the university was reestablished in 1971 after a regrouping of several preexisting higher education establishments. It would go on to add additional campuses in Cholet and Saumur in 1987 and 2004, respectively. Today, the University of Angers counts more than 25,000 students across all campuses. Academics The University of Angers offers bachelors, vocational bachelors, masters, and doctoral degrees across its 8 faculties and institutes: *Faculty of Tou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Oxford
The University of Oxford is a collegiate research university in Oxford, England. There is evidence of teaching as early as 1096, making it the oldest university in the English-speaking world and the world's second-oldest university in continuous operation. It grew rapidly from 1167 when Henry II banned English students from attending the University of Paris. After disputes between students and Oxford townsfolk in 1209, some academics fled north-east to Cambridge where they established what became the University of Cambridge. The two English ancient universities share many common features and are jointly referred to as ''Oxbridge''. Both are ranked among the most prestigious universities in the world. The university is made up of thirty-nine semi-autonomous constituent colleges, five permanent private halls, and a range of academic departments which are organised into four divisions. All the colleges are self-governing institutions within the university, each controlling ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apoptosis
Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes ( morphology) and death. These changes include blebbing, cell shrinkage, nuclear fragmentation, chromatin condensation, DNA fragmentation, and mRNA decay. The average adult human loses between 50 and 70 billion cells each day due to apoptosis. For an average human child between eight and fourteen years old, approximately twenty to thirty billion cells die per day. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis is a highly regulated and controlled process that confers advantages during an organism's life cycle. For example, the separation of fingers and toes in a developing human embryo occurs because cells between the digits undergo apoptosis. Unlike necrosis, apoptosis produces cell fragments called apopt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nonsteroidal Anti-inflammatory Drug
Non-steroidal anti-inflammatory drugs (NSAID) are members of a therapeutic drug class which reduces pain, decreases inflammation, decreases fever, and prevents blood clots. Side effects depend on the specific drug, its dose and duration of use, but largely include an increased risk of gastrointestinal ulcers and bleeds, heart attack, and kidney disease. The term ''non-steroidal'', common from around 1960, distinguishes these drugs from corticosteroids, which during the 1950s had acquired a bad reputation due to overuse and side-effect problems after their initial introduction in 1948. NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (the COX-1 and COX-2 isoenzymes). In cells, these enzymes are involved in the synthesis of key biological mediators, namely prostaglandins, which are involved in inflammation, and thromboxanes, which are involved in blood clotting. There are two general types of NSAIDs available: non-selective, and COX-2 selective. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotrophin
Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death – allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to ''form'' neurons. Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis. Terminology According to the United States National Library of Medicine's medica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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