Carl Axel Gemzell
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Carl Axel Gemzell
Carl Axel Gemzell (January 4, 1910 in Motala, Sweden – February 11, 2007 in Norrtälje, Sweden) was a Swedish medical doctor and pioneer in reproductive endocrinology. Life Gemzell studied medicine at the Karolinska Institute and was registered as a physician in 1940. After training in surgery and obstetrics and gynecology he studied experimental endocrinology at the Wenner-Gren Institute and received his PhD in 1948. Subsequently, he worked at the Institute for Experimental Biology of the University of California, Berkeley before returning to Sweden. He became professor in Ob-Gyn at the Uppsala University Faculty of Medicine. After his mandatory retirement in Sweden in 1975, he moved to the USA where he continued to work at SUNY Downstate Medical Center, Brooklyn, New York, and later at the University of Puerto Rico in San Juan before he retired in Florida and, after the death of his wife, returned to Sweden. Work Gemzell developed methods to extract the human growth hormon ...
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Motala
Motala () is a locality and the seat of Motala Municipality, Östergötland County, Sweden with 29,823 inhabitants (41,956 in the entire municipality) in 2010. It is the third largest city of Östergötland, following Linköping and Norrköping. Motala is situated on the eastern shore of Lake Vättern and is regarded as the main centre of both the Göta Canal and the surrounding lake region. History Motala Church dates from the 13th century. For several centuries, Motala remained a small village, mainly regarded as a stopping post on the road to the nearby town of Vadstena, one of the cultural centres of medieval Sweden. However, King Gustav Vasa had a manor house built at Motala and later Queen Kristina had a summer residence built at the spa resort of Medevi, 20 km north of the town. When the Göta Canal was built in the early 19th century, Motala became an important town for the trade on the canal. The builder of the canal, Baltzar von Platen, has his grave beside it ...
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Cadaver
A cadaver or corpse is a dead human body that is used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue to repair a defect in a living human being. Students in medical school study and dissect cadavers as a part of their education. Others who study cadavers include archaeologists and arts students. The term ''cadaver'' is used in courts of law (and, to a lesser extent, also by media outlets such as newspapers) to refer to a dead body, as well as by recovery teams searching for bodies in natural disasters. The word comes from the Latin word ''cadere'' ("to fall"). Related terms include ''cadaverous'' (resembling a cadaver) and ''cadaveric spasm'' (a muscle spasm causing a dead body to twitch or jerk). A cadaver graft (also called “postmortem graft”) is the grafting of tissue from a dead body onto a living human to repair a defect or disfigurement. Cadavers can be observed for their sta ...
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Swedish Obstetricians
Swedish or ' may refer to: Anything from or related to Sweden, a country in Northern Europe. Or, specifically: * Swedish language, a North Germanic language spoken primarily in Sweden and Finland ** Swedish alphabet, the official alphabet used by the Swedish language * Swedish people or Swedes, persons with a Swedish ancestral or ethnic identity ** A national or citizen of Sweden, see demographics of Sweden ** Culture of Sweden * Swedish cuisine See also * * Swedish Church (other) * Swedish Institute (other) * Swedish invasion (other) * Swedish Open (other) Swedish Open is a tennis tournament. Swedish Open may also refer to: *Swedish Open (badminton) * Swedish Open (table tennis) *Swedish Open (squash) *Swedish Open (darts) The Swedish Open is a darts tournament established in 1969, held in Malm ... {{disambig Language and nationality disambiguation pages ...
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Stockholm
Stockholm () is the Capital city, capital and List of urban areas in Sweden by population, largest city of Sweden as well as the List of urban areas in the Nordic countries, largest urban area in Scandinavia. Approximately 980,000 people live in the Stockholm Municipality, municipality, with 1.6 million in the Stockholm urban area, urban area, and 2.4 million in the Metropolitan Stockholm, metropolitan area. The city stretches across fourteen islands where Mälaren, Lake Mälaren flows into the Baltic Sea. Outside the city to the east, and along the coast, is the island chain of the Stockholm archipelago. The area has been settled since the Stone Age, in the 6th millennium BC, and was founded as a city in 1252 by Swedish statesman Birger Jarl. It is also the county seat of Stockholm County. For several hundred years, Stockholm was the capital of Finland as well (), which then was a part of Sweden. The population of the municipality of Stockholm is expected to reach o ...
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Moderna Museet
Moderna Museet ("the Museum of Modern Art"), Stockholm, Sweden, is a state museum for modern and contemporary art located on the island of Skeppsholmen in central Stockholm, opened in 1958. In 2009, the museum opened a new branch in Malmö in the south of Sweden, Moderna Museet Malmö. History The museum was opened in 9May 1958. In 2009, the museum opened a new branch in the building previously known as Rooseum in Malmö. Directors * 1958–1973: Pontus Hultén * 1973–1977: Philip von Schantz * 1977–1979: Karin Lindegren * 1980–1989: Olle Granath * 1989–1995: Björn Springfeldt * 1996–2001: David Elliott * 2001–2010: Lars Nittve * 2010–2018: Daniel Birnbaum * 2018–2019: Ann-Sofi Noring (acting) * 2019–present: Gitte Ørskou Collection The museum houses Swedish and international modern and contemporary art, including pieces by Pablo Picasso and Salvador Dalí and a model of the Tatlin's Tower. The museum's collection includes also key works by arti ...
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Pregnancy Test
A pregnancy test is used to determine whether a female is pregnant or not. The two primary methods are testing for the female pregnancy hormone (human chorionic gonadotropin (hCG)) in blood or urine using a pregnancy test kit, and scanning with ultrasonography. Testing blood for hCG results in the earliest detection of pregnancy. Almost all pregnant women will have a positive urine pregnancy test one week after the first day of a missed menstrual period. Types Human chorionic gonadotropin (hCG) Identified in the early 20th century, human chorionic gonadotropin (hCG) is a glycoprotein hormone that rises quickly in the first few weeks of pregnancy, typically reaching a peak at 8- to 10-weeks gestational age. hCG is produced by what will become the placenta. hCG testing can be performed with a blood ( serum) sample (typically done in a medical facility) or with urine (which can be performed in a medical facility or at home). The assays used to detect the presence of hCG in b ...
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Creutzfeldt–Jakob Disease
Creutzfeldt–Jakob disease (CJD), also known as subacute spongiform encephalopathy or neurocognitive disorder due to prion disease, is an invariably fatal degenerative brain disorder. Early symptoms include memory problems, behavioral changes, poor coordination, and visual disturbances. Later symptoms include dementia, involuntary movements, blindness, weakness, and coma. About 70% of people die within a year of diagnosis. The name Creutzfeldt–Jakob disease was introduced by Walther Spielmeyer in 1922, after the German neurologists Hans Gerhard Creutzfeldt and Alfons Maria Jakob. CJD is caused by a type of abnormal protein known as a prion. Infectious prions are misfolded proteins that can cause normally folded proteins to also become misfolded. About 85% of cases of CJD occur for unknown reasons, while about 7.5% of cases are inherited in an autosomal dominant manner. Exposure to brain or spinal tissue from an infected person may also result in spread. There is no evid ...
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Pergonal
Menotropin (also called human menopausal gonadotropin or hMG) is a hormonally active medication for the treatment of fertility disturbances. Frequently the plural is used as the medication is a mixture of gonadotropins. Menotropins are extracted from the urine of postmenopausal women. Description and usage Urine of postmenopausal women reflects the hypergonadotropic state of menopause -levels of follicle stimulating hormone (FSH) and luteinizing hormone (LH) are high - and contain a mixture of these gonadotropins. Other protein substances may be present, including small amounts of human chorionic gonadotropin (hCG). In 1949 Piero Donini found a relatively simple method to extract gonadotropins from urine of postmenopausal women. Menotropins were successfully introduced into clinical use by Bruno Lunenfeld in 1961. While earlier menotropin medications contained FSH and LH at a 1:1 ratio, the recognition that it is FSH that is critical for follicle stimulation has led to developmen ...
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Serono
Serono was a biotechnology company headquartered in Geneva, Switzerland. It was acquired by the German pharmaceutical company Merck in 2006. The company was founded as the Serono Pharmacological Institute by Cesare Serono in 1906 in Rome, Italy. A key step in its development was the discovery of a method of extracting urinary gonadotropins by Dr. Piero Donini. Serono was incorporated in 1987 and the holding company, Ares-Serono S.A., changed its name to Serono S.A. in May 2000. Serono develops and markets pharmaceuticals in the fields of reproductive health, multiple sclerosis, growth & metabolism and dermatology. The eight biotechnology products are available in four core therapeutic areas: neurology for the treatment of relapsing forms of multiple sclerosis, reproductive health for treatments of infertility, dermatology, where Serono has launched biologics in Europe for moderate-to-severe psoriasis, and growth and metabolism for treatments for HIV-associated wasting and g ...
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Ovarian Hyperstimulation Syndrome
Ovarian hyperstimulation syndrome (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in other women in very rare cases. Most cases are mild, but rarely the condition is severe and can lead to serious illness or death. Signs and symptoms Symptoms are set into 3 categories: mild, moderate, and severe. Mild symptoms include abdominal bloating and feeling of fullness, nausea, diarrhea, and slight weight gain. Moderate symptoms include excessive weight gain (weight gain of greater than 2 pounds per day), increased abdominal girth, vomiting, diarrhea, darker urine, decreased urine output, excessive thirst, and skin and/or hair feeling dry (in addition to mild symptoms). Severe symptoms are fullness/bloating above the waist, shortness of breath, pleural effusion, urination significantly darker or has ceased, calf and chest pains, marked abdominal bloating or distention, and lower abdominal pains (in addition to mild and mod ...
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Multiple Pregnancy
A multiple birth is the culmination of one multiple pregnancy, wherein the mother gives birth to two or more babies. A term most applicable to vertebrate species, multiple births occur in most kinds of mammals, with varying frequencies. Such births are often named according to the number of offspring, as in ''twins'' and ''triplets''. In non-humans, the whole group may also be referred to as a ''litter'', and multiple births may be more common than single births. Multiple births in humans are the exception and can be exceptionally rare in the largest mammals. A multiple pregnancy may be the result of the fertilization of a single egg that then splits to create identical fetuses, or it may be the result of the fertilization of multiple eggs that create fraternal ("non-identical") fetuses, or it may be a combination of these factors. A multiple pregnancy from a single zygote is called ''monozygotic'', from two zygotes is called ''dizygotic'', or from three or more zygotes is calle ...
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Follicle-stimulating Hormone
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland and regulates the development, growth, pubertal maturation, and reproductive processes of the body. FSH and luteinizing hormone (LH) work together in the reproductive system. Structure FSH is a 35.5 kDa glycoprotein heterodimer, consisting of two polypeptide units, alpha and beta. Its structure is similar to those of luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The alpha subunits of the glycoproteins LH, FSH, TSH, and hCG are identical and consist of 96 amino acids, while the beta subunits vary. Both subunits are required for biological activity. FSH has a beta subunit of 111 amino acids (FSH β), which confers its specific biologic action, and is responsible for interaction with the follicle-stimulating hormone receptor. The sugar port ...
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