IARC Group 1 Carcinogens
   HOME





IARC Group 1 Carcinogens
IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). This category is used when there is sufficient evidence of carcinogenicity in humans. Exceptionally, an agent ( chemical mixture) may be placed in this category when evidence of carcinogenicity in humans is less than sufficient, but when there is sufficient evidence of carcinogenicity in experimental animals and strong evidence in exposed humans that the agent (mixture) acts through a relevant mechanism of carcinogenicity. This list focuses on the hazard linked to the agents. This means that while carcinogens are capable of causing cancer, it does not take their risk into account, which is the probability of causing a cancer, given the level of exposure to this carcinogen. The list is up to date as of January 2024. Agents Infectious conditions Viruses *Human immunodeficiency viru ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Chemical Mixture
In chemistry, a mixture is a material made up of two or more different chemical substances which can be separated by physical method. It is an impure substance made up of 2 or more elements or compounds mechanically mixed together in any proportion. A mixture is the physical combination of two or more substances in which the identities are retained and are mixed in the form of Solution (chemistry), solutions, Suspension (chemistry), suspensions or colloids. Mixtures are one product of mechanically blending or mixing chemical substances such as chemical element, elements and Compound (chemistry), compounds, without chemical bonding or other chemical change, so that each ingredient substance retains its own chemical properties and makeup. Despite the fact that there are no chemical changes to its constituents, the physical properties of a mixture, such as its melting point, may differ from those of the components. Some mixtures can be separation process, separated into their compone ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Acetaldehyde
Acetaldehyde (IUPAC systematic name ethanal) is an organic compound, organic chemical compound with the chemical formula, formula , sometimes abbreviated as . It is a colorless liquid or gas, boiling near room temperature. It is one of the most important aldehydes, occurring widely in nature and being produced on a large scale in industry. Acetaldehyde occurs naturally in coffee, bread, and ripe fruit, and is produced by plants. It is also produced by the partial oxidation of ethanol by the liver enzyme alcohol dehydrogenase and is a contributing cause of hangover after alcohol (drug), alcohol consumption. Pathways of exposure include air, water, land, or groundwater, as well as drink and smoke. Consumption of disulfiram inhibits acetaldehyde dehydrogenase, the enzyme responsible for the metabolism of acetaldehyde, thereby causing it to build up in the body. International Agency for Research on Cancer, The International Agency for Research on Cancer (IARC) has listed acetaldehyde ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Crocidolite
Riebeckite is a sodium-rich member of the amphibole group of silicate minerals, chemical formula Na2(Fe2+3Fe3+2)Si8O22(OH)2. It forms a solid solution series with magnesioriebeckite. It crystallizes in the monoclinic system, usually as long prismatic crystals showing a diamond-shaped cross section, but also in fibrous, bladed, acicular, columnar, and radiating forms. Its Mohs hardness is 5.0–6.0, and its specific gravity is 3.0–3.4. Cleavage is perfect, two directions in the shape of a diamond; fracture is uneven, splintery. It is often translucent to nearly opaque. Name and discovery Riebeckite was first described in 1888 for an occurrence on Socotra Island, Aden Governorate, Yemen, and named for German explorer Emil Riebeck (1853–1885). The mineral is also known as crocidolite. Occurrence Riebeckite typically forms dark-blue elongated to fibrous crystals in highly alkali granites, syenites, rarely in felsic volcanics, granite pegmatites and schist. It occurs in banded ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Chrysotile
Chrysotile or white asbestos is the most commonly encountered form of asbestos, accounting for approximately 95% of the asbestos in the United StatesOccupational Safety and Health Administration, U.S. Department of Labor (2007)29 C.F.R. 1910.1001 Appendix J. and a similar proportion in other countries.Institut national de recherche sur la sécurité (1997).Amiante." ''Fiches toxicologiques.'' n° 167. (in French) It is a soft, fibrous silicate mineral in the serpentine subgroup of phyllosilicates; as such, it is distinct from other asbestiform minerals in the amphibole group. Its idealized chemical formula is Mg( Si O)( OH). The material has physical properties which make it desirable for inclusion in building materials, but poses serious health risks when dispersed into air and inhaled. Polytypes Three polytypes of chrysotile are known. These are very difficult to distinguish in hand specimens, and polarized light microscopy must normally be used. Some older publ ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Anthophyllite
Anthophyllite is an orthorhombic amphibole mineral: ☐Mg2Mg5Si8O22(OH)2 (☐ is for a vacancy, a point defect in the crystal structure), magnesium iron inosilicate hydroxide. Anthophyllite is polymorphic with cummingtonite. Some forms of anthophyllite are lamellar or fibrous and are classed as asbestos. The name is derived from the Latin word ''anthophyllum'', meaning ''clove'', an allusion to the most common color of the mineral. The Anthophyllite crystal is characterized by its perfect cleavage along directions 126 degrees and 54 degrees. Occurrence Anthophyllite is the product of metamorphism of magnesium-rich rocks, especially ultrabasic igneous rocks and impure dolomitic shales. It also forms as a retrograde product rimming relict orthopyroxenes and olivine, and as an accessory mineral in cordierite-bearing gneisses and schists. Anthophyllite also occurs as a retrograde metamorphic mineral derived from ultramafic rocks along with serpentinite. Occurrence in ultramaf ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Amosite
Grunerite is a mineral of the amphibole group of minerals with formula Fe7 Si8 O22( OH)2. It is the iron endmember of the grunerite- cummingtonite series. It forms as fibrous, columnar or massive aggregates of crystals. The crystals are monoclinic prismatic. The luster is glassy to pearly with colors ranging from green, brown to dark grey. The Mohs hardness is 5 to 6 and the specific gravity is 3.4 to 3.5. It was discovered in 1853 and named after Emmanuel-Louis Gruner (1809–1883), the Swiss-French chemist who first analysed it. Amosite (fibrous grunerite) Amosite is a rare asbestiform variety of grunerite that was mined as asbestos Asbestos ( ) is a group of naturally occurring, Toxicity, toxic, carcinogenic and fibrous silicate minerals. There are six types, all of which are composed of long and thin fibrous Crystal habit, crystals, each fibre (particulate with length su ... predominantly in the eastern part of the Transvaal Province of South Africa. The origin of t ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Actinolite
Actinolite is an amphibole silicate mineral with the chemical formula . Etymology The name ''actinolite'' is derived from the Greek word ''aktis'' (), meaning "beam" or "ray", because of the mineral's fibrous nature. Mineralogy Actinolite is an intermediate member in a solid-solution series between magnesium-rich tremolite, , and iron-rich ferro-actinolite, . Mg and Fe ions can be freely exchanged in the crystal structure. Like tremolite, asbestiform actinolite is regulated as asbestos. Occurrence Actinolite is commonly found in metamorphic rocks, such as contact aureoles surrounding cooled intrusive igneous rocks. It also occurs as a product of metamorphism of magnesium-rich limestones. The old mineral name ''uralite'' is at times applied to an alteration product of primary pyroxene by a mixture composed largely of actinolite. The metamorphosed gabbro or diabase rock bodies, referred to as epidiorite, contain a considerable amount of this ''uralitic'' alteration. F ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Asbestos
Asbestos ( ) is a group of naturally occurring, Toxicity, toxic, carcinogenic and fibrous silicate minerals. There are six types, all of which are composed of long and thin fibrous Crystal habit, crystals, each fibre (particulate with length substantially greater than width) being composed of many microscopic "fibrils" that can be released into the atmosphere by Abrasion (mechanical), abrasion and other processes. Inhalation of asbestos fibres can lead to various dangerous lung conditions, including mesothelioma, asbestosis, and lung cancer. As a result of these health effects, asbestos is considered a serious Health hazard, health and safety hazard. Archaeological studies have found evidence of asbestos being used as far back as the Stone Age to strengthen ceramic pots, but large-scale mining began at the end of the 19th century when manufacturers and builders began using asbestos for its desirable physical properties. Asbestos is an excellent Thermal insulation, thermal and In ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


Inorganic Compounds By Element
Although most compounds are referred to by their IUPAC systematic names (following IUPAC nomenclature), traditional names have also been kept where they are in wide use or of significant historical interests. A Ac * Actinium(III) chloride – * Actinium(III) fluoride – * Actinium(III) oxide – * Actinium(III) sulfide - * Actinium(III) nitrate - * Actinium(III) bromide - * Actinium(III) hydroxide - * Actinium(III) iodide - * Actinium(III) phosphate - Al * Aluminium antimonide – AlSb * Aluminium arsenate – * Aluminium arsenide – AlAs * Aluminium diboride – * Aluminium bromide – * Aluminium carbide – * Aluminium iodide – * Aluminium nitride – AlN * Aluminium oxide – * Aluminium phosphide – AlP * Aluminium chloride – * Aluminium fluoride – * Aluminium hydroxide – * Aluminium nitrate – * Aluminium sulfide – * Aluminium sulfate – * Aluminium potassium sulfate – Am * Americium(II) bromide − * ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Arsenic
Arsenic is a chemical element; it has Symbol (chemistry), symbol As and atomic number 33. It is a metalloid and one of the pnictogens, and therefore shares many properties with its group 15 neighbors phosphorus and antimony. Arsenic is notoriously toxic. It occurs naturally in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. It has various Allotropes of arsenic, allotropes, but only the grey form, which has a metallic appearance, is important to industry. The primary use of arsenic is in alloys of lead (for example, in car batteries and ammunition). Arsenic is also a common n-type dopant in semiconductor electronic devices, and a component of the III–V compound semiconductor gallium arsenide. Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining with the increasing recognition of the persistent tox ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

Aristolochic Acid
Aristolochic acids () are a family of carcinogenic, mutagenic, and nephrotoxic phytochemicals commonly found in the flowering plant family Aristolochiaceae (birthworts). Aristolochic acid (AA) I is the most abundant one. The family Aristolochiaceae includes the genera ''Aristolochia'' (birthwort) and ''Asarum'' (wild ginger), which are both commonly used in Chinese herbal medicine. Despite the host plants having a long history of use in traditional medicine, modern clinical research suggests aristolochic acids cause kidney and liver cancer. The FDA has issued warnings regarding consumption of AA-containing supplements. History Early medical uses Birthwort plants, and the aristolochic acids they contain, were quite common in ancient Greek and Roman medical texts, well-established as an herb there by the fifth century BC. Birthworts appeared in Ayurvedic texts by 400 AD, and in Chinese texts later in the fifth century. In these ancient times, it was used to treat kidney and urina ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]  


picture info

4-Aminobiphenyl
4-Aminobiphenyl (4-ABP) is an organic compound with the formula C6H5C6H4NH2. It is an amine derivative of biphenyl. It is a colorless solid, although aged samples can appear colored. 4-Aminobiphenyl was commonly used in the past as a rubber antioxidant and an intermediate for dyes. Exposure to this aryl-amine can happen through contact with chemical dyes and from inhalation of cigarette smoke. Researches showed that 4-aminobiphenyl is responsible for bladder cancer in humans and dogs by damaging DNA. Due to its carcinogenic effects, commercial production of 4-aminobiphenyl ceased in the United States in the 1950s. Synthesis and reactivity Like other aniline derivatives, 4-aminobiphenyl is weakly Base (chemistry), basic. It is prepared by reduction of 4-Nitrobiphenyl, 4-nitrobiphenyl: : Together with other isomers, 4-nitrobiphenyl is obtained by nitration of biphenyl. 4-Aminobiphenyl can in principle be obtained by reduction of 4-azidobiphenyl with diphosphorus tetraiodide (P2I4). ...
[...More Info...]      
[...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]